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Aliases for TMEM191C Gene

Aliases for TMEM191C Gene

  • Transmembrane Protein 191C 2 3
  • KB-1323B2.6 3

External Ids for TMEM191C Gene

Previous GeneCards Identifiers for TMEM191C Gene

  • GC22P020151
  • GC22P021821
  • GC22P021825

Summaries for TMEM191C Gene

GeneCards Summary for TMEM191C Gene

TMEM191C (Transmembrane Protein 191C) is a Protein Coding gene. An important paralog of this gene is TMEM191B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM191C Gene

Genomics for TMEM191C Gene

Regulatory Elements for TMEM191C Gene

Genomic Location for TMEM191C Gene

Start:
21,466,423 bp from pter
End:
21,471,269 bp from pter
Size:
4,847 bases
Orientation:
Plus strand

Genomic View for TMEM191C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM191C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM191C Gene

Proteins for TMEM191C Gene

  • Protein details for TMEM191C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGB0-T191C_HUMAN
    Recommended name:
    Transmembrane protein 191C
    Protein Accession:
    A6NGB0
    Secondary Accessions:

    Protein attributes for TMEM191C Gene

    Size:
    347 amino acids
    Molecular mass:
    39292 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM191C Gene

Proteomics data for TMEM191C Gene at MOPED

Post-translational modifications for TMEM191C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM191C Gene

REFSEQ proteins:

No data available for DME Specific Peptides for TMEM191C Gene

Domains for TMEM191C Gene

Protein Domains for TMEM191C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM191C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NGB0

UniProtKB/Swiss-Prot:

T191C_HUMAN :
  • A6NGB0
Family:
  • Belongs to the TMEM191 family.
genes like me logo Genes that share domains with TMEM191C: view

No data available for Gene Families for TMEM191C Gene

Function for TMEM191C Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM191C Gene

Localization for TMEM191C Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM191C Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM191C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM191C: view

No data available for Subcellular locations from COMPARTMENTS for TMEM191C Gene

Pathways for TMEM191C Gene

SuperPathways for TMEM191C Gene

No Data Available

Interacting Proteins for TMEM191C Gene

Gene Ontology (GO) - Biological Process for TMEM191C Gene

None

No data available for Pathways by source for TMEM191C Gene

Transcripts for TMEM191C Gene

mRNA/cDNA for TMEM191C Gene

(3) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(18) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM191C Gene

Transmembrane protein 191C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM191C

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM191C Gene

No ASD Table

Relevant External Links for TMEM191C Gene

GeneLoc Exon Structure for
TMEM191C
ECgene alternative splicing isoforms for
TMEM191C

Expression for TMEM191C Gene

mRNA expression in normal human tissues for TMEM191C Gene

mRNA differential expression in normal tissues according to GTEx for TMEM191C Gene

This gene is overexpressed in Testis (11.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM191C Gene

SOURCE GeneReport for Unigene cluster for TMEM191C Gene Hs.376511

genes like me logo Genes that share expressions with TMEM191C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM191C Gene

Orthologs for TMEM191C Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TMEM191C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM191C 35
  • 96.83 (n)
  • 95.97 (a)
Species with no ortholog for TMEM191C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM191C Gene

ENSEMBL:
Gene Tree for TMEM191C (if available)
TreeFam:
Gene Tree for TMEM191C (if available)

Paralogs for TMEM191C Gene

Paralogs for TMEM191C Gene

genes like me logo Genes that share paralogs with TMEM191C: view

Variants for TMEM191C Gene

Sequence variations from dbSNP and Humsavar for TMEM191C Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs395295 -- 21,468,455(+) GAGGT(C/G)TTTAG intron-variant
rs430214 -- 21,468,436(+) GGTGC(C/T)TGAGC intron-variant
rs430858 -- 21,468,537(+) GTGGG(C/T)GGGGC intron-variant
rs444588 -- 21,468,547(+) CGGGG(A/G)ATGTG intron-variant
rs452545 -- 21,468,485(+) TGAGC(G/T)GGGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM191C Gene

Variant ID Type Subtype PubMed ID
nsv436864 CNV Insertion 17901297
nsv914437 CNV Gain 21882294
dgv4875n71 CNV Gain 21882294
nsv7350 OTHER Inversion 18451855
nsv428386 CNV Loss 18775914
nsv914448 CNV Loss 21882294
dgv4878n71 CNV Gain 21882294
nsv469545 CNV Gain 16826518
nsv471596 CNV Gain+Loss 15918152
nsv511071 OTHER Inversion 20534489
nsv442791 CNV CNV 18776908
dgv4879n71 CNV Loss 21882294
nsv914457 CNV Loss 21882294
nsv914458 CNV Loss 21882294
nsv834145 CNV Loss 17160897
dgv4880n71 CNV Gain 21882294
nsv914461 CNV Gain 21882294
nsv914462 CNV Gain 21882294
esv2678291 CNV Deletion 23128226
esv25508 CNV Gain+Loss 19812545

Relevant External Links for TMEM191C Gene

HapMap Linkage Disequilibrium report
TMEM191C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM191C Gene

Disorders for TMEM191C Gene

No disorders were found for TMEM191C Gene.

No data available for UniProtKB/Swiss-Prot for TMEM191C Gene

Publications for TMEM191C Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 4

Products for TMEM191C Gene

Sources for TMEM191C Gene

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