Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM191B Gene

Aliases for TMEM191B Gene

  • Transmembrane Protein 191B 2 3

External Ids for TMEM191B Gene

Previous GeneCards Identifiers for TMEM191B Gene

  • GC22P018757
  • GC22P020379
  • GC22P004856
  • GC22P020381
  • GC22P020383

Summaries for TMEM191B Gene

GeneCards Summary for TMEM191B Gene

TMEM191B (Transmembrane Protein 191B) is a Protein Coding gene. An important paralog of this gene is TMEM191C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM191B Gene

Genomics for TMEM191B Gene

Regulatory Elements for TMEM191B Gene

Genomic Location for TMEM191B Gene

Start:
18,527,802 bp from pter
End:
18,530,573 bp from pter
Size:
2,772 bases
Orientation:
Plus strand

Genomic View for TMEM191B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM191B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM191B Gene

Proteins for TMEM191B Gene

  • Protein details for TMEM191B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7N4-T191B_HUMAN
    Recommended name:
    Transmembrane protein 191B
    Protein Accession:
    P0C7N4
    Secondary Accessions:
    • A0A087WXW8

    Protein attributes for TMEM191B Gene

    Size:
    346 amino acids
    Molecular mass:
    39065 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM191B Gene

Proteomics data for TMEM191B Gene at MOPED

Post-translational modifications for TMEM191B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM191B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM191B Gene

Domains for TMEM191B Gene

Protein Domains for TMEM191B Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TMEM191B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7N4

UniProtKB/Swiss-Prot:

T191B_HUMAN :
  • P0C7N4
Family:
  • Belongs to the TMEM191 family.
genes like me logo Genes that share domains with TMEM191B: view

No data available for Gene Families for TMEM191B Gene

Function for TMEM191B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM191B Gene

Localization for TMEM191B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM191B Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM191B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM191B: view

No data available for Subcellular locations from COMPARTMENTS for TMEM191B Gene

Pathways for TMEM191B Gene

SuperPathways for TMEM191B Gene

No Data Available

Interacting Proteins for TMEM191B Gene

Gene Ontology (GO) - Biological Process for TMEM191B Gene

None

No data available for Pathways by source for TMEM191B Gene

Transcripts for TMEM191B Gene

mRNA/cDNA for TMEM191B Gene

(2) REFSEQ mRNAs :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM191B Gene

No ASD Table

Relevant External Links for TMEM191B Gene

GeneLoc Exon Structure for
TMEM191B
ECgene alternative splicing isoforms for
TMEM191B

Expression for TMEM191B Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for TMEM191B Gene

Orthologs for TMEM191B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TMEM191B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM191C 35
  • 97.21 (n)
  • 96.53 (a)
Species with no ortholog for TMEM191B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM191B Gene

ENSEMBL:
Gene Tree for TMEM191B (if available)
TreeFam:
Gene Tree for TMEM191B (if available)

Paralogs for TMEM191B Gene

Paralogs for TMEM191B Gene

Selected SIMAP similar genes for TMEM191B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMEM191B: view

Variants for TMEM191B Gene

Sequence variations from dbSNP and Humsavar for TMEM191B Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs2909302 -- 18,528,726(+) GGGTG(A/G)GGCAG intron-variant
rs2930761 -- 18,529,038(+) GGAAC(C/T)GCAGA reference, missense
rs2930762 -- 18,529,904(+) CCGGG(A/C)TGGGC intron-variant
rs55698413 -- 18,529,098(+) GGTGC(C/T)TGAGC intron-variant
rs56006201 -- 18,529,199(+) GTGGG(C/T)GGGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM191B Gene

Variant ID Type Subtype PubMed ID
nsv435744 CNV Deletion 17901297
dgv16n31 CNV Duplication 19718026
nsv518950 CNV Gain 19592680
esv33990 CNV Loss 17666407
nsv820540 CNV Duplication 20802225
esv26930 CNV Gain+Loss 19812545
dgv4865n71 CNV Gain 21882294
nsv914377 CNV Gain 21882294
nsv510803 CNV Loss 20534489
nsv914378 CNV Gain 21882294
dgv4866n71 CNV Gain 21882294
nsv511636 CNV Loss 21212237

Relevant External Links for TMEM191B Gene

HapMap Linkage Disequilibrium report
TMEM191B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM191B Gene

Disorders for TMEM191B Gene

No disorders were found for TMEM191B Gene.

No data available for UniProtKB/Swiss-Prot for TMEM191B Gene

Publications for TMEM191B Gene

  1. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for TMEM191B Gene

Sources for TMEM191B Gene

Back to Top

Content