Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM19 Gene

Aliases for TMEM19 Gene

  • Transmembrane Protein 19 2 3
  • TMEM195 6
  • AGMO 6

External Ids for TMEM19 Gene

Previous GeneCards Identifiers for TMEM19 Gene

  • GC12P070367
  • GC12P070368
  • GC12P072079
  • GC12P069128

Summaries for TMEM19 Gene

GeneCards Summary for TMEM19 Gene

TMEM19 (Transmembrane Protein 19) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM19 Gene

Genomics for TMEM19 Gene

Regulatory Elements for TMEM19 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM19 Gene

Start:
71,686,087 bp from pter
End:
71,705,046 bp from pter
Size:
18,960 bases
Orientation:
Plus strand

Genomic View for TMEM19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM19 Gene

Proteins for TMEM19 Gene

  • Protein details for TMEM19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96HH6-TMM19_HUMAN
    Recommended name:
    Transmembrane protein 19
    Protein Accession:
    Q96HH6
    Secondary Accessions:
    • B2RDL2
    • Q53FY3
    • Q9NV41

    Protein attributes for TMEM19 Gene

    Size:
    336 amino acids
    Molecular mass:
    36392 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM19 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM19 Gene

Proteomics data for TMEM19 Gene at MOPED

Post-translational modifications for TMEM19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM19 Gene

No data available for DME Specific Peptides for TMEM19 Gene

Domains for TMEM19 Gene

Protein Domains for TMEM19 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96HH6

UniProtKB/Swiss-Prot:

TMM19_HUMAN :
  • Q96HH6
Family:
  • Belongs to the TMEM19 family.
genes like me logo Genes that share domains with TMEM19: view

No data available for Gene Families for TMEM19 Gene

Function for TMEM19 Gene

Gene Ontology (GO) - Molecular Function for TMEM19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with TMEM19: view

Phenotypes for TMEM19 Gene

GenomeRNAi human phenotypes for TMEM19:
genes like me logo Genes that share phenotypes with TMEM19: view

Animal Model Products

CRISPR Products

miRNA for TMEM19 Gene

miRTarBase miRNAs that target TMEM19

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM19 Gene

Localization for TMEM19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM19 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM19 Gene COMPARTMENTS Subcellular localization image for TMEM19 gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM19: view

Pathways for TMEM19 Gene

SuperPathways for TMEM19 Gene

No Data Available

Interacting Proteins for TMEM19 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000266673%0d%0a9606.ENSP00000354032%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: Q96HH6-TMM19_HUMAN ENSP00000266673 for TMEM19 Gene via MINT STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for TMEM19 Gene

None

No data available for Pathways by source for TMEM19 Gene

Transcripts for TMEM19 Gene

Unigene Clusters for TMEM19 Gene

Transmembrane protein 19:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM19

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TMEM19

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM19 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8
SP1: -
SP2:
SP3: -

Relevant External Links for TMEM19 Gene

GeneLoc Exon Structure for
TMEM19
ECgene alternative splicing isoforms for
TMEM19

Expression for TMEM19 Gene

mRNA expression in normal human tissues for TMEM19 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TMEM19 Gene

SOURCE GeneReport for Unigene cluster for TMEM19 Gene Hs.644802

genes like me logo Genes that share expressions with TMEM19: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM19 Gene

Orthologs for TMEM19 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TMEM19 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM19 35
  • 99.6 (n)
  • 98.81 (a)
TMEM19 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM19 35
  • 88.26 (n)
  • 88.36 (a)
TMEM19 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM19 35
  • 90 (n)
  • 94.48 (a)
TMEM19 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem19 35
  • 83.98 (n)
  • 87.46 (a)
Tmem19 16
Tmem19 36
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM19 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 86 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Tmem19 35
  • 86.56 (n)
  • 89.06 (a)
chicken
(Gallus gallus)
Aves TMEM19 35
  • 72.24 (n)
  • 74.93 (a)
TMEM19 36
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM19 36
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.11046 35
tmem19 35
  • 73.13 (n)
  • 78.21 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13441 35
zebrafish
(Danio rerio)
Actinopterygii tmem19 35
  • 64.69 (n)
  • 66.36 (a)
tmem19 36
  • 69 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012271 35
  • 53.8 (n)
  • 49.82 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10171 35
  • 51.22 (n)
  • 47.3 (a)
CG10171 36
  • 45 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G19930 35
  • 48.74 (n)
  • 41.52 (a)
rice
(Oryza sativa)
Liliopsida Os01g0507300 35
  • 44.32 (n)
  • 36.7 (a)
Species with no ortholog for TMEM19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM19 Gene

ENSEMBL:
Gene Tree for TMEM19 (if available)
TreeFam:
Gene Tree for TMEM19 (if available)

Paralogs for TMEM19 Gene

No data available for Paralogs for TMEM19 Gene

Variants for TMEM19 Gene

Sequence variations from dbSNP and Humsavar for TMEM19 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1043780 -- 71,703,559(+) TGGGG(A/T)AGTAC utr-variant-3-prime
rs1043781 -- 71,703,638(+) AAAAA(C/G)TAATA utr-variant-3-prime
rs1048897 -- 71,701,179(+) TCTAG(C/T)GAAAG utr-variant-3-prime
rs1880893 -- 71,704,338(-) ACTAG(A/T)CCTTT downstream-variant-500B
rs2013933 -- 71,702,461(-) gtgca(C/T)gcctg utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for TMEM19 Gene

Variant ID Type Subtype PubMed ID
nsv832451 CNV Loss 17160897
nsv524634 CNV Loss 19592680

Relevant External Links for TMEM19 Gene

HapMap Linkage Disequilibrium report
TMEM19

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM19 Gene

Disorders for TMEM19 Gene

No disorders were found for TMEM19 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM19 Gene

Publications for TMEM19 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for TMEM19 Gene

Sources for TMEM19 Gene

Back to Top

Content