External Ids for TMEM189 Gene
Co-transcription of this gene and the neighboring downstream gene (ubiquitin-conjugating enzyme E2 variant 1) generates a rare read-through transcript, which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The protein encoded by this individual gene lacks a UEV1 domain but includes three transmembrane regions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
GeneCards Summary for TMEM189 Gene
TMEM189 (Transmembrane Protein 189) is a Protein Coding gene. Among its related pathways are PI-3K cascade and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is TMEM189-UBE2V1.