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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TMEM185A Gene

protein-coding GIFtS: 48
GCID: GC0XM148678

transmembrane protein 185A

(Previous names: chromosome X open reading frame 13, family with sequence...)
(Previous symbols: CXorf13, FAM11A)

Explore 6 diseases affiliated with
TMEM185A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Transmembrane Protein 185A¹ ²		Chromosome X Open Reading Frame 13¹
FAM11A¹ ² ³ ⁵		Ee3¹
CXorf13¹ ² ³		Fragile Site, Folic Acid Type, Rare, Fra(X)(Q28) F²
Family With Sequence Similarity 11, Member A¹ ²		Protein FAM11A³
FRAXF² ⁵

External Ids:	HGNC: 17125¹	Entrez Gene: 84548²	Ensembl: ENSG00000155984⁷	OMIM: 300031⁵	UniProtKB: Q8NFB2³

Export aliases for TMEM185A gene to outside databases

Previous GC identifers: GC0XM148487 GC0XM137631

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TMEM185A:

The protein encoded by this gene is predicted to be a transmembrane protein, but this has not been experimentally

determined. This gene is better known for localizing to the CpG island of the fragile site FRAXF. The 5-prime

untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem

CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional

silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear

phenotypic manner. Two transcript variants encoding different isoforms have been found for this gene.(provided by

RefSeq, Mar 2010)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000023.10 NC_018934.1 NT_011681.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TMEM185A gene promoter:
POU2F2 (Oct-2.1) Oct-B1 oct-B3 oct-B2 FOXD1 POU2F2 POU2F2C POU2F1 POU2F1a POU2F2B
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMEM185A promoter sequence

Search SABiosciences Chromatin IP Primers for TMEM185A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM185A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28

TMEM185A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM185A gene location

GeneLoc information about chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XM148678: view genomic region (about GC identifiers)

Start:	148,678,216 bp from pter	End:	148,713,568 bp from pter
Size:	35,353 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: T185A_HUMAN, Q8NFB2 (See protein sequence)

Recommended Name: Transmembrane protein 185A

Size: 350 amino acids; 40647 Da

Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Sequence caution: Sequence=AAH13793.1; Type=Erroneous initiation;

Secondary accessions: B3KTZ3 Q3SYH1 Q96CW3 Q96KE8

Explore the universe of human proteins at neXtProt for TMEM185A: NX_Q8NFB2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NFB2

TMEM185A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001167563.1 NP_115897.1

ENSEMBL proteins:

ENSP00000429207 ENSP00000359449 ENSP00000427814 ENSP00000429625 ENSP00000427766

ENSP00000428852 ENSP00000428659 ENSP00000443119

Human Recombinant Protein Products:

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	Uscn Proteins for TMEM185A

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

TMEM185A for ontologies About GeneDecksing

TMEM185A Antibody Products:

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Assay Products for TMEM185A:

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	GenScript Custom Assay Services for TMEM185A
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	Uscn ELISAs and CLIAs for TMEM185A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TMEM185A for domains About GeneDecksing

1 InterPro domain/family:

IPR019396 TM_Fragile-X-F-assoc

Graphical View of Domain Structure for InterPro Entry Q8NFB2

ProtoNet protein and cluster: Q8NFB2

UniProtKB/Swiss-Prot: T185A_HUMAN, Q8NFB2

Similarity: Belongs to the TMEM185 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone: TMEM185A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM185A
		8 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM185A:
		hsa-miR-100* hsa-miR-548p hsa-let-7a-2* hsa-miR-466 hsa-let-7g* hsa-miR-3915 hsa-miR-3662 hsa-miR-3941

		SwitchGear 3'UTR luciferase reporter plasmid: TMEM185A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for TMEM185A

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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM185A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TMEM185A
		Search LifeMap BioReagents cell lines for TMEM185A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM185A

1 GenomeRNAi human phenotype for TMEM185A:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TMEM185A

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for TMEM185A (ENSP00000359449⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GBF1	ENSP00000359000⁴	STRING: ENSP00000359000

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMEM185A
Search CenterWatch for drugs/clinical trials and news about TMEM185A / T185A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TMEM185A gene (2 alternative transcripts):

NM_001174092.1 NM_032508.2

Unigene Cluster for TMEM185A:

Transmembrane protein 185A

Hs.522172 [show with all ESTs]

Unigene Representative Sequence: AK128688

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000513505 ENST00000316916(uc022cgl.1) ENST00000519015 ENST00000502858

ENST00000502618 ENST00000507237(uc004fdp.4) ENST00000502900 ENST00000517359

ENST00000511776 ENST00000536359(uc011mxp.2 uc004fdo.3)

miRNA Products:		OriGene 3'-UTR Clone: TMEM185A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM185A
		8 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM185A:
		hsa-miR-100* hsa-miR-548p hsa-let-7a-2* hsa-miR-466 hsa-let-7g* hsa-miR-3915 hsa-miR-3662 hsa-miR-3941

		SwitchGear 3'UTR luciferase reporter plasmid: TMEM185A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM185A (see all 3) OriGene siRNA: TMEM185A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM185A

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM185A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM185A (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): TMEM185A (NM_032508)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM185A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM185A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM185A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TMEM185A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM185A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM185A

Additional cDNA sequence:

AF353675.1 AF530473.1 AK096308.1 AK097391.1 AK128688.1 AK297335.1 BC013793.1 BC022405.1

BC103820.1 BC103821.1 BC103822.1

11 DOTS entries:

DT.100022373 DT.95091770 DT.100761713 DT.100761714 DT.100642382 DT.91666793 DT.95260135 DT.100673794

DT.311496 DT.121288557 DT.102826238

24/91 AceView cDNA sequences (see all 91):

AK096308 NM_032508 AI694721 BE326400 CD557648 AA350736 AA340539 AF530473

BF724625 BX279896 AI078112 BQ224383 BE327053 BF445184 BM469272 AF353675

BC013793 BE218960 BE045420 BE348698 BM458996 BE552442 F11108 AI338920

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM185A (see all 6) About this scheme

ExUns:	1	^	2a	·	2b	^	3	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	^	7	^	8a	·	8b
SP1:															-
SP2:							-		-		-				-
SP3:			-		-		-		-		-		-		-
SP4:
SP5:

ECgene alternative splicing isoforms for TMEM185A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMEM185A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAATAAAAG

About this image

TMEM185A expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TMEM185A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM185A

SOURCE GeneReport for Unigene cluster: Hs.522172

SABiosciences Custom PCR Arrays for TMEM185A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM185A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TMEM185A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM185A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM185A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM185A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TMEM185A gene from 6/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	BC023829^{1 , 5}	cDNA sequence BC023829^{1, 5}	90.79(n)¹ 99.69(a)¹		X (36.04 cM)⁵ 236848¹ NM_001033328.2¹ NP_001028500.1¹ 70459753⁵
chicken (Gallus gallus)	Aves	TMEM185A¹	transmembrane protein 185A	82.1(n) 95.71(a)		422391 XM_420360.3 XP_420360.3
lizard (Anolis carolinensis)	Reptilia	TMEM185A⁶	--	94(a)	1 ↔ 1	GL343310.1(1062948-1066391)
zebrafish (Danio rerio)	Actinopterygii	zgc:63572¹	zgc:63572	76.29(n) 88(a)		393409 NM_200437.1 NP_956731.1
fruit fly (Drosophila melanogaster)	Insecta	CG14194⁶	--	43(a)	1 → many	X(19087600-19090080)
worm (Caenorhabditis elegans)	Secernentea	CELE_Y116A8C.9¹	Protein Y116A8C.9	50.38(n) 41.97(a)		178473 NM_070609.3 NP_503010.2

ENSEMBL Gene Tree for TMEM185A (if available)
TreeFam Gene Tree for TMEM185A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TMEM185A gene

TMEM185B²

2 SIMAP similar genes for TMEM185A using alignment to 10 protein entries: T185A_HUMAN (see all proteins):

FAM11A TMEM185B

TMEM185A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr X pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186408209^1,2		--	148678073(+)	`CTCATC/TCTAAA`	3	--	ds500¹ us2k¹		0	--	--	--	--
rs147716632^1,2		--	148678802(+)	`CCGTTC/GTGGCA`	3	--	ut3¹ us2k¹		0	--	--	--	--
rs142482822^1,2		--	148678807(+)	`CTGGCA/GGTAGC`	3	--	us2k¹ ut3¹		0	--	--	--	--
rs199844446^1,2		--	148680435(+)	`CGGGT-/CCTGGCC`	2	--	int¹		0	--	--	--	--
rs394928^1,2	F	--	148683015(-)	`CTGTGC/TGAATC`	2	--	int¹		1		MN	184
rs141656902^1,2	C,	--	148683898(+)	`ATTTC-/ATTTT AATTT`	2	--	int¹		0	--	--	--	--
rs190243730^1,2		--	148683997(+)	`CCCCAA/GAGATT`	2	--	int¹		0	--	--	--	--
rs148934738^1,2		--	148684222(+)	`ATAGGC/TTTCCT`	2	--	int¹		0	--	--	--	--
rs143645058^1,2		--	148684295(+)	`GAGGAC/TGAAGG`	2	--	int¹		0	--	--	--	--
rs182456130^1,2		--	148684302(+)	`AAGGGC/TAGAAA`	2	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TMEM185A (148678216 - 148713568 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for TMEM185A
4 Indels: 83827 83826 29284 97061

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM185A

DNA2.0 Custom Variant and Variant Library Synthesis for TMEM185A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TMEM185A for disorders           About GeneDecksing

OMIM gene information: 300031    OMIM disorders: --

6 diseases for TMEM185A:    About MalaCards

pervasive developmental disorder fragile x syndrome atypical autism intellectual disability

mental disorders neuronitis

4 diseases from the University of Copenhagen DISEASES database for TMEM185A:

Intellectual disability Fragile X syndrome Atypical autism dentatorubral-pallidoluysian atrophy

Export disorders for TMEM185A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TMEM185A gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with TMEM185A)

Utopia: connect your pdf to the dynamic
world of online information

A novel gene, FAM11A, associated with the FRAXF CpG island is transcriptionally silent in FRAXF full mutation. (PubMed id 12404111)^{1, 2, 3, 9} Shaw M.A.... Gecz J. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor. (PubMed id 15525354)¹ Maurer M.H....Schneider A. (2004)
Genetic and neurological evaluation in a sample of individuals with pervasive developmental disorders. (PubMed id 12806492)¹ Steiner C.E....Marques-de-Faria A.P. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Population genetics of the FRAXE and FRAXF GCC repeat s, and a novel CGG repeat, in Xq28. (PubMed id 9415475)¹ Ritchie R.J....Davies K.E. (1997)
Lack of expansion of triplet repeats in the FMR1, FRA XE, and FRAXF loci in male multiplex families with autism and pervasive develop mental disorders. (PubMed id 8844091)¹ Holden J.J....White B.N. (1996)
Trinucleotide repeats at the FRAXF locus: frequency a nd distribution in the general population. (PubMed id 8844097)¹ Holden J.J....White B.N. (1996)
Isolation of a GCC repeat showing expansion in FRAXF, a fragile site distal to FRAXA and FRAXE. (PubMed id 7874164)¹ Parrish J.E....Nelson D.L. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84548	HGNC: 17125	AceView: FAM11A	Ensembl:ENSG00000155984	euGenes: HUgn84548
ECgene: TMEM185A	H-InvDB: TMEM185A

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TMEM185A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TMEM185A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for TMEM185A gene:
Search GeneIP for patents involving TMEM185A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM185A		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM185A
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMEM185A
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	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM185A

	GenScript Custom Purified and Recombinant Proteins Services for TMEM185A		GenScript cDNA clones with any tag delivered in your preferred vector for TMEM185A
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM185A

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM185A

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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TMEM185A Gene

transmembrane protein 185A

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TMEM185A Gene

transmembrane protein 185A

Aliasesfor TMEM185A gene

Summariesfor TMEM185A gene

Genomic Viewsfor TMEM185A gene

Proteinsfor TMEM185A gene

Protein Domains /Familiesfor TMEM185A gene

Functionfor TMEM185A gene

Pathways & Interactionsfor TMEM185A gene

Drugs & Compoundsfor TMEM185A gene

Transcriptsfor TMEM185A gene

Expression for TMEM185A gene

Orthologsfor TMEM185A gene

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Genomic Variantsfor TMEM185A gene

Disorders / Diseasesfor TMEM185A gene

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External Searches for TMEM185A gene

Genome Databases showing TMEM185A gene

Other Databases showing TMEM185A gene

Specialized Databases showing TMEM185A gene

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Aliases
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Summaries
for TMEM185A gene

Genomic Views
for TMEM185A gene

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for TMEM185A gene

Protein Domains /
Families
for TMEM185A gene

Function
for TMEM185A gene

Pathways & Interactions
for TMEM185A gene

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for TMEM185A gene

Transcripts
for TMEM185A gene

Expression
for TMEM185A gene

Orthologs
for TMEM185A gene

Paralogs
for TMEM185A gene

Genomic Variants
for TMEM185A gene

Disorders / Diseases
for TMEM185A gene

Publications
for TMEM185A gene

Intellectual Property
for TMEM185A gene

Products
for TMEM185A gene