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Aliases for TMEM184A Gene

Aliases for TMEM184A Gene

  • Transmembrane Protein 184A 2 3 5

External Ids for TMEM184A Gene

Previous GeneCards Identifiers for TMEM184A Gene

  • GC07M001551
  • GC07M001502
  • GC07M001581

Summaries for TMEM184A Gene

GeneCards Summary for TMEM184A Gene

TMEM184A (Transmembrane Protein 184A) is a Protein Coding gene. An important paralog of this gene is TMEM184C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM184A Gene

Genomics for TMEM184A Gene

Regulatory Elements for TMEM184A Gene

Enhancers for TMEM184A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM184A on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM184A Gene

1,542,235 bp from pter
1,560,821 bp from pter
18,587 bases
Minus strand

Genomic View for TMEM184A Gene

Genes around TMEM184A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM184A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM184A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM184A Gene

Proteins for TMEM184A Gene

  • Protein details for TMEM184A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 184A
    Protein Accession:
    Secondary Accessions:
    • Q8TBQ6

    Protein attributes for TMEM184A Gene

    413 amino acids
    Molecular mass:
    45777 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC86522.2; Type=Miscellaneous discrepancy; Note=Probable cloning artifact. Aberrant splice sites.; Evidence={ECO:0000305};

neXtProt entry for TMEM184A Gene

Proteomics data for TMEM184A Gene at MOPED

Post-translational modifications for TMEM184A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM184A Gene

Antibody Products

No data available for DME Specific Peptides for TMEM184A Gene

Domains & Families for TMEM184A Gene

Protein Domains for TMEM184A Gene


Suggested Antigen Peptide Sequences for TMEM184A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TMEM184 family.
  • Belongs to the TMEM184 family.
genes like me logo Genes that share domains with TMEM184A: view

No data available for Gene Families for TMEM184A Gene

Function for TMEM184A Gene

Phenotypes for TMEM184A Gene

GenomeRNAi human phenotypes for TMEM184A:
genes like me logo Genes that share phenotypes with TMEM184A: view

Animal Model Products

CRISPR Products

miRNA for TMEM184A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM184A Gene

Localization for TMEM184A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM184A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM184A Gene COMPARTMENTS Subcellular localization image for TMEM184A gene
Compartment Confidence
endosome 3
plasma membrane 3
nucleus 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for TMEM184A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005768 endosome ISS --
GO:0030667 secretory granule membrane ISS --
GO:0048471 perinuclear region of cytoplasm ISS --
genes like me logo Genes that share ontologies with TMEM184A: view

Pathways & Interactions for TMEM184A Gene

SuperPathways for TMEM184A Gene

No Data Available

Interacting Proteins for TMEM184A Gene

Gene Ontology (GO) - Biological Process for TMEM184A Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM184A Gene

Drugs & Compounds for TMEM184A Gene

No Compound Related Data Available

Transcripts for TMEM184A Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM184A Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ·
SP1: - - - - -
SP2: - - -
SP3: - - - - - - -
SP4: - - - - -
SP5: - -
SP6: -
SP7: -
SP11: - -

ExUns: 14c

Relevant External Links for TMEM184A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM184A Gene

mRNA expression in normal human tissues for TMEM184A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM184A Gene

This gene is overexpressed in Esophagus - Mucosa (x11.7), Vagina (x4.4), and Skin - Not Sun Exposed (Suprapubic) (x4.1).

Protein differential expression in normal tissues from HIPED for TMEM184A Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM184A Gene

SOURCE GeneReport for Unigene cluster for TMEM184A Gene Hs.592174

genes like me logo Genes that share expression patterns with TMEM184A: view

Protein tissue co-expression partners for TMEM184A Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for TMEM184A Gene

Orthologs for TMEM184A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TMEM184A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM184A 35
  • 85.53 (n)
  • 82.38 (a)
TMEM184A 36
  • 75 (a)
(Canis familiaris)
Mammalia TMEM184A 35
  • 87.73 (n)
  • 85.47 (a)
TMEM184A 36
  • 82 (a)
(Mus musculus)
Mammalia Tmem184a 35
  • 81.47 (n)
  • 82.28 (a)
Tmem184a 16
Gm26938 36
  • 54 (a)
(Rattus norvegicus)
Mammalia Tmem184a 35
  • 81.15 (n)
  • 83.01 (a)
(Monodelphis domestica)
Mammalia TMEM184A 36
  • 68 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM184A 36
  • 68 (a)
(Gallus gallus)
Aves TMEM184A 35
  • 79.18 (n)
  • 77.75 (a)
TMEM184A 36
  • 69 (a)
(Anolis carolinensis)
Reptilia TMEM184A 36
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem184a 35
  • 70.15 (n)
  • 76.14 (a)
(Danio rerio)
Actinopterygii tmem184a 35
  • 72.6 (n)
  • 73.15 (a)
wufi16g03 35
tmem184a 36
  • 64 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12004 36
  • 46 (a)
(Caenorhabditis elegans)
Secernentea F40E10.6 36
  • 51 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 21 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G26740 35
  • 50.77 (n)
  • 45.36 (a)
(Oryza sativa)
Liliopsida Os07g0244300 35
  • 50.83 (n)
  • 41.58 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 58 (a)
Species with no ortholog for TMEM184A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM184A Gene

Gene Tree for TMEM184A (if available)
Gene Tree for TMEM184A (if available)

Paralogs for TMEM184A Gene

Paralogs for TMEM184A Gene

(3) SIMAP similar genes for TMEM184A Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with TMEM184A: view

Variants for TMEM184A Gene

Sequence variations from dbSNP and Humsavar for TMEM184A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs3779607 - 1,547,026(+) GCCGC(C/T)GGGGT downstream-variant-500B, reference, missense
rs17852421 - 1,555,432(+) AGTTC(A/G)CTGAC reference, missense, utr-variant-5-prime
rs892523 -- 1,543,652(+) GAGAC(A/G)GTATC utr-variant-3-prime
rs1124669 -- 1,546,603(+) CACTC(A/G)CAGCT utr-variant-3-prime
rs1124871 -- 1,549,132(+) GGTGC(A/G)CTGTG intron-variant, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for TMEM184A Gene

Variant ID Type Subtype PubMed ID
nsv887128 CNV Loss 21882294
nsv471182 CNV Loss 18288195
dgv2045e1 CNV Complex 17122850
dgv7090n71 CNV Loss 21882294
dgv7093n71 CNV Loss 21882294
dgv7095n71 CNV Loss 21882294
nsv464247 CNV Loss 19166990
dgv7098n71 CNV Loss 21882294
nsv823970 CNV Gain 20364138
nsv887218 CNV Gain+Loss 21882294
nsv887219 CNV Loss 21882294
dgv7100n71 CNV Loss 21882294
nsv887221 CNV Gain 21882294
nsv830879 CNV Gain+Loss 17160897
nsv830880 CNV Loss 17160897
nsv887224 CNV Loss 21882294
dgv7101n71 CNV Loss 21882294
dgv7102n71 CNV Loss 21882294
nsv5615 CNV Loss 18451855
nsv887231 CNV Loss 21882294
nsv887232 CNV Loss 21882294
nsv887233 CNV Loss 21882294
nsv823974 CNV Loss 20364138
nsv482100 CNV Gain 20164927
esv2733773 CNV Deletion 23290073
nsv823975 CNV Loss 20364138
nsv823977 CNV Gain 20364138

Variation tolerance for TMEM184A Gene

Residual Variation Intolerance Score: 98.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.14; 69.35% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TMEM184A Gene

Disorders for TMEM184A Gene

Relevant External Links for TMEM184A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TMEM184A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM184A Gene

Publications for TMEM184A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for TMEM184A Gene

Sources for TMEM184A Gene