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Aliases for TMEM184A Gene

Aliases for TMEM184A Gene

  • Transmembrane Protein 184A 2 3

External Ids for TMEM184A Gene

Previous GeneCards Identifiers for TMEM184A Gene

  • GC07M001551
  • GC07M001502
  • GC07M001581

Summaries for TMEM184A Gene

GeneCards Summary for TMEM184A Gene

TMEM184A (Transmembrane Protein 184A) is a Protein Coding gene. An important paralog of this gene is TMEM184C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM184A Gene

Genomics for TMEM184A Gene

Regulatory Elements for TMEM184A Gene

Genomic Location for TMEM184A Gene

Start:
1,542,235 bp from pter
End:
1,560,821 bp from pter
Size:
18,587 bases
Orientation:
Minus strand

Genomic View for TMEM184A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM184A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM184A Gene

Proteins for TMEM184A Gene

  • Protein details for TMEM184A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZMB5-T184A_HUMAN
    Recommended name:
    Transmembrane protein 184A
    Protein Accession:
    Q6ZMB5
    Secondary Accessions:
    • Q8TBQ6

    Protein attributes for TMEM184A Gene

    Size:
    413 amino acids
    Molecular mass:
    45777 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC86522.2; Type=Miscellaneous discrepancy; Note=Probable cloning artifact. Aberrant splice sites.; Evidence={ECO:0000305};

neXtProt entry for TMEM184A Gene

Proteomics data for TMEM184A Gene at MOPED

Post-translational modifications for TMEM184A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM184A Gene

No data available for DME Specific Peptides for TMEM184A Gene

Domains for TMEM184A Gene

Protein Domains for TMEM184A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM184A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZMB5

UniProtKB/Swiss-Prot:

T184A_HUMAN :
  • Q6ZMB5
Family:
  • Belongs to the TMEM184 family.
genes like me logo Genes that share domains with TMEM184A: view

No data available for Gene Families for TMEM184A Gene

Function for TMEM184A Gene

Phenotypes for TMEM184A Gene

GenomeRNAi human phenotypes for TMEM184A:
genes like me logo Genes that share phenotypes with TMEM184A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM184A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM184A Gene

Localization for TMEM184A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM184A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM184A Gene COMPARTMENTS Subcellular localization image for TMEM184A gene
Compartment Confidence
plasma membrane 3
endosome 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for TMEM184A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0031901 early endosome membrane IEA --
genes like me logo Genes that share ontologies with TMEM184A: view

Pathways for TMEM184A Gene

SuperPathways for TMEM184A Gene

No Data Available

Interacting Proteins for TMEM184A Gene

Gene Ontology (GO) - Biological Process for TMEM184A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0018992 germ-line sex determination IEA --
GO:0032880 regulation of protein localization IEA --
GO:0051046 regulation of secretion IEA --
genes like me logo Genes that share ontologies with TMEM184A: view

No data available for Pathways by source for TMEM184A Gene

Transcripts for TMEM184A Gene

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM184A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM184A Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ·
SP1: - - - - -
SP2: - - -
SP3: - - - - - - -
SP4: - - - - -
SP5: - -
SP6: -
SP7: -
SP8:
SP9:
SP10:
SP11: - -

ExUns: 14c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:

Relevant External Links for TMEM184A Gene

GeneLoc Exon Structure for
TMEM184A
ECgene alternative splicing isoforms for
TMEM184A

Expression for TMEM184A Gene

mRNA expression in normal human tissues for TMEM184A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM184A Gene

This gene is overexpressed in Esophagus - Mucosa (11.7), Vagina (4.4), and Skin - Not Sun Exposed (Suprapubic) (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM184A Gene

SOURCE GeneReport for Unigene cluster for TMEM184A Gene Hs.592174

genes like me logo Genes that share expressions with TMEM184A: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TMEM184A Gene

Orthologs for TMEM184A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TMEM184A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM184A 35
  • 85.53 (n)
  • 82.38 (a)
TMEM184A 36
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM184A 35
  • 87.73 (n)
  • 85.47 (a)
TMEM184A 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm26938 36
  • 54 (a)
OneToOne
Tmem184a 35
  • 81.47 (n)
  • 82.28 (a)
Tmem184a 16
oppossum
(Monodelphis domestica)
Mammalia TMEM184A 36
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM184A 36
  • 68 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem184a 35
  • 81.15 (n)
  • 83.01 (a)
chicken
(Gallus gallus)
Aves TMEM184A 35
  • 79.18 (n)
  • 77.75 (a)
TMEM184A 36
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM184A 36
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem184a 35
  • 70.15 (n)
  • 76.14 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem184a 35
  • 72.6 (n)
  • 73.15 (a)
tmem184a 36
  • 64 (a)
OneToOne
wufi16g03 35
fruit fly
(Drosophila melanogaster)
Insecta CG12004 36
  • 46 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F40E10.6 36
  • 51 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 21 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G26740 35
  • 50.77 (n)
  • 45.36 (a)
rice
(Oryza sativa)
Liliopsida Os07g0244300 35
  • 50.83 (n)
  • 41.58 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 58 (a)
OneToMany
Species with no ortholog for TMEM184A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM184A Gene

ENSEMBL:
Gene Tree for TMEM184A (if available)
TreeFam:
Gene Tree for TMEM184A (if available)

Paralogs for TMEM184A Gene

Paralogs for TMEM184A Gene

Selected SIMAP similar genes for TMEM184A Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with TMEM184A: view

Variants for TMEM184A Gene

Sequence variations from dbSNP and Humsavar for TMEM184A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs751413 -- 1,546,964(+) TCCTC(C/T)GAGGG synonymous-codon, reference, missense
rs892523 -- 1,543,652(+) GAGAC(A/G)GTATC utr-variant-3-prime
rs1124669 -- 1,546,603(+) CACTC(A/G)CAGCT utr-variant-3-prime
rs1124871 -- 1,549,132(+) GGTGC(A/G)CTGTG intron-variant, reference, synonymous-codon
rs1140270 -- 1,551,888(+) ctgaa(A/G)gtgcg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM184A Gene

Variant ID Type Subtype PubMed ID
nsv887128 CNV Loss 21882294
nsv471182 CNV Loss 18288195
dgv2045e1 CNV Complex 17122850
dgv7090n71 CNV Loss 21882294
dgv7093n71 CNV Loss 21882294
dgv7095n71 CNV Loss 21882294
nsv464247 CNV Loss 19166990
dgv7098n71 CNV Loss 21882294
nsv823970 CNV Gain 20364138
nsv887218 CNV Gain+Loss 21882294
nsv887219 CNV Loss 21882294
dgv7100n71 CNV Loss 21882294
nsv887221 CNV Gain 21882294
nsv830879 CNV Gain+Loss 17160897
nsv830880 CNV Loss 17160897
nsv887224 CNV Loss 21882294
dgv7101n71 CNV Loss 21882294
dgv7102n71 CNV Loss 21882294
nsv5615 CNV Loss 18451855
nsv887231 CNV Loss 21882294
nsv887232 CNV Loss 21882294
nsv887233 CNV Loss 21882294
nsv823974 CNV Loss 20364138
nsv482100 CNV Gain 20164927
esv2733773 CNV Deletion 23290073
nsv823975 CNV Loss 20364138
nsv823977 CNV Gain 20364138

Relevant External Links for TMEM184A Gene

HapMap Linkage Disequilibrium report
TMEM184A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM184A Gene

Disorders for TMEM184A Gene

No disorders were found for TMEM184A Gene.

No data available for UniProtKB/Swiss-Prot for TMEM184A Gene

Publications for TMEM184A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for TMEM184A Gene

  • antibodies-online peptides for TMEM184A
  • antibodies-online antibodies for TMEM184A
  • antibodies-online kits for TMEM184A

Sources for TMEM184A Gene

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