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Aliases for TMEM183A Gene

Aliases for TMEM183A Gene

  • Transmembrane Protein 183A 2 3
  • C1orf37 3 4
  • Chromosome 1 Open Reading Frame 37 2

External Ids for TMEM183A Gene

Previous HGNC Symbols for TMEM183A Gene

  • C1orf37

Previous GeneCards Identifiers for TMEM183A Gene

  • GC01P201245

Summaries for TMEM183A Gene

GeneCards Summary for TMEM183A Gene

TMEM183A (Transmembrane Protein 183A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM183A Gene

Genomics for TMEM183A Gene

Regulatory Elements for TMEM183A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM183A Gene

203,007,386 bp from pter
203,024,848 bp from pter
17,463 bases
Plus strand

Genomic View for TMEM183A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM183A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM183A Gene

Proteins for TMEM183A Gene

  • Protein details for TMEM183A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 183A
    Protein Accession:
    Secondary Accessions:
    • A8K5W1
    • Q6NW15
    • Q96E06

    Protein attributes for TMEM183A Gene

    376 amino acids
    Molecular mass:
    42826 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM183A Gene


neXtProt entry for TMEM183A Gene

Proteomics data for TMEM183A Gene at MOPED

Post-translational modifications for TMEM183A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM183A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM183A Gene

Domains for TMEM183A Gene

Protein Domains for TMEM183A Gene


Suggested Antigen Peptide Sequences for TMEM183A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TMEM183 family.
  • Belongs to the TMEM183 family.
genes like me logo Genes that share domains with TMEM183A: view

No data available for Gene Families for TMEM183A Gene

Function for TMEM183A Gene

Gene Ontology (GO) - Molecular Function for TMEM183A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM183A: view

Animal Model Products

CRISPR Products

miRNA for TMEM183A Gene

miRTarBase miRNAs that target TMEM183A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM183A Gene

Localization for TMEM183A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM183A Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM183A Gene COMPARTMENTS Subcellular localization image for TMEM183A gene
Compartment Confidence
cytosol 2
nucleus 2
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for TMEM183A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM183A: view

Pathways for TMEM183A Gene

SuperPathways for TMEM183A Gene

No Data Available

Interacting Proteins for TMEM183A Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000356211 Q8IXX5-T183A_HUMAN for TMEM183A Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for TMEM183A Gene


No data available for Pathways by source for TMEM183A Gene

Transcripts for TMEM183A Gene

Unigene Clusters for TMEM183A Gene

Transmembrane protein 183A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM183A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM183A Gene

No ASD Table

Relevant External Links for TMEM183A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM183A Gene

mRNA expression in normal human tissues for TMEM183A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for TMEM183A Gene Hs.497443

genes like me logo Genes that share expressions with TMEM183A: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for TMEM183A Gene

Orthologs for TMEM183A Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM183A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC534797 35
  • 94.5 (n)
  • 95.74 (a)
TMEM183 36
  • 95 (a)
(Canis familiaris)
Mammalia TMEM183A 35
  • 94.15 (n)
  • 97.34 (a)
TMEM183A 36
  • 97 (a)
(Mus musculus)
Mammalia Tmem183a 35
  • 91.11 (n)
  • 93.6 (a)
Tmem183a 16
Tmem183a 36
  • 94 (a)
(Pan troglodytes)
Mammalia TMEM183A 35
  • 99.82 (n)
  • 100 (a)
TMEM183A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Tmem183a 35
  • 92.11 (n)
  • 94.68 (a)
(Monodelphis domestica)
Mammalia TMEM183A 36
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM183A 36
  • 87 (a)
(Gallus gallus)
Aves TMEM183A 35
  • 78.97 (n)
  • 84.85 (a)
TMEM183A 36
  • 76 (a)
(Anolis carolinensis)
Reptilia TMEM183A 36
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.10764 35
tmem183a 35
  • 64.04 (n)
  • 65.45 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.18610 35
(Danio rerio)
Actinopterygii tmem183a 35
  • 65.83 (n)
  • 68.07 (a)
tmem183a 36
  • 68 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13905 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004102 35
  • 43.91 (n)
  • 35.68 (a)
fruit fly
(Drosophila melanogaster)
Insecta fsd 36
  • 21 (a)
Species with no ortholog for TMEM183A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM183A Gene

Gene Tree for TMEM183A (if available)
Gene Tree for TMEM183A (if available)

Paralogs for TMEM183A Gene

(1) SIMAP similar genes for TMEM183A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMEM183A: view

No data available for Paralogs for TMEM183A Gene

Variants for TMEM183A Gene

Sequence variations from dbSNP and Humsavar for TMEM183A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs782784 -- 203,019,612(-) taaat(A/G)tattG intron-variant
rs782785 -- 203,018,878(-) aagag(A/G)gtctt intron-variant
rs782786 -- 203,018,853(-) cccct(G/T)ttggc intron-variant
rs782787 -- 203,018,668(-) gttac(C/T)cagaa intron-variant
rs782788 -- 203,018,642(-) tagca(A/G)cacaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM183A Gene

Variant ID Type Subtype PubMed ID
nsv832370 CNV Loss 17160897
nsv4132 CNV Insertion 18451855

Relevant External Links for TMEM183A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM183A Gene

Disorders for TMEM183A Gene

Relevant External Links for TMEM183A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for TMEM183A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for TMEM183A Gene

Publications for TMEM183A Gene

  1. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PMID: 19536175) Ehret G.B. … Chakravarti A. (Eur. J. Hum. Genet. 2009) 3 48
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup. (PMID: 16644869) Yu H. … Wang W. (Hum. Mol. Genet. 2006) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 3

Products for TMEM183A Gene

Sources for TMEM183A Gene

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