Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM179 Gene

Aliases for TMEM179 Gene

  • Transmembrane Protein 179 2 3
  • Transmembrane Protein 179A 3 4
  • C14orf90 3 4
  • TMEM179A 3 4
  • Chromosome 14 Open Reading Frame 90 2

External Ids for TMEM179 Gene

Previous HGNC Symbols for TMEM179 Gene

  • C14orf90

Previous GeneCards Identifiers for TMEM179 Gene

  • GC14M104132
  • GC14M105061
  • GC14M085256
  • GC14M104942

Summaries for TMEM179 Gene

GeneCards Summary for TMEM179 Gene

TMEM179 (Transmembrane Protein 179) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM179 Gene

Genomics for TMEM179 Gene

Regulatory Elements for TMEM179 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM179 Gene

Start:
104,474,678 bp from pter
End:
104,605,647 bp from pter
Size:
130,970 bases
Orientation:
Minus strand

Genomic View for TMEM179 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM179 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM179 Gene

Proteins for TMEM179 Gene

  • Protein details for TMEM179 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZVK1-T179A_HUMAN
    Recommended name:
    Transmembrane protein 179
    Protein Accession:
    Q6ZVK1
    Secondary Accessions:

    Protein attributes for TMEM179 Gene

    Size:
    233 amino acids
    Molecular mass:
    26378 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM179 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM179 Gene

Proteomics data for TMEM179 Gene at MOPED

Post-translational modifications for TMEM179 Gene

  • Glycosylation at Asn51
  • Modification sites at PhosphoSitePlus

Other Protein References for TMEM179 Gene

No data available for DME Specific Peptides for TMEM179 Gene

Domains for TMEM179 Gene

Protein Domains for TMEM179 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM179 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZVK1

UniProtKB/Swiss-Prot:

T179A_HUMAN :
  • Q6ZVK1
Family:
  • Belongs to the TMEM179 family.
genes like me logo Genes that share domains with TMEM179: view

No data available for Gene Families for TMEM179 Gene

Function for TMEM179 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM179

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM179 Gene

Localization for TMEM179 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM179 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM179 Gene COMPARTMENTS Subcellular localization image for TMEM179 gene
Compartment Confidence
extracellular 2
plasma membrane 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for TMEM179 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM179: view

Pathways for TMEM179 Gene

SuperPathways for TMEM179 Gene

No Data Available

Interacting Proteins for TMEM179 Gene

Gene Ontology (GO) - Biological Process for TMEM179 Gene

None

No data available for Pathways by source for TMEM179 Gene

Transcripts for TMEM179 Gene

Unigene Clusters for TMEM179 Gene

Transmembrane protein 179:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM179

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TMEM179
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM179 Gene

No ASD Table

Relevant External Links for TMEM179 Gene

GeneLoc Exon Structure for
TMEM179
ECgene alternative splicing isoforms for
TMEM179

Expression for TMEM179 Gene

mRNA expression in normal human tissues for TMEM179 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM179 Gene

This gene is overexpressed in Pituitary (7.9), Brain - Cortex (4.5), Brain - Putamen (basal ganglia) (4.4), Brain - Hypothalamus (4.3), and Brain - Frontal Cortex (BA9) (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for TMEM179 Gene

SOURCE GeneReport for Unigene cluster for TMEM179 Gene Hs.655004

genes like me logo Genes that share expressions with TMEM179: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TMEM179 Gene

Orthologs for TMEM179 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM179 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM179 35
  • 99.24 (n)
  • 98.86 (a)
TMEM179 36
  • 77 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM179 35
  • 93.53 (n)
  • 95.69 (a)
TMEM179 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM179 35
  • 92.74 (n)
  • 93.78 (a)
TMEM179 36
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem179 35
  • 89.7 (n)
  • 93.56 (a)
Tmem179 16
Tmem179 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM179 36
  • 52 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM179 36
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem179 35
  • 89.56 (n)
  • 93.13 (a)
chicken
(Gallus gallus)
Aves TMEM179 35
  • 79.02 (n)
  • 83.19 (a)
TMEM179 36
  • 62 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM179 36
  • 61 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem179 35
  • 73.13 (n)
  • 76.29 (a)
zebrafish
(Danio rerio)
Actinopterygii CABZ01084273.1 36
  • 50 (a)
OneToMany
LOC100537383 35
  • 68.1 (n)
  • 66.38 (a)
tmem179 36
  • 50 (a)
OneToMany
TMEM179 (2 of 3) 36
  • 33 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004210 35
  • 46.94 (n)
  • 30.94 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13603 35
  • 50.24 (n)
  • 29.95 (a)
CG13603 36
  • 22 (a)
OneToOne
Species with no ortholog for TMEM179:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM179 Gene

ENSEMBL:
Gene Tree for TMEM179 (if available)
TreeFam:
Gene Tree for TMEM179 (if available)

Paralogs for TMEM179 Gene

No data available for Paralogs for TMEM179 Gene

Variants for TMEM179 Gene

Sequence variations from dbSNP and Humsavar for TMEM179 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1135470 -- 104,591,036(-) GGGGA(C/T)TGGGC utr-variant-3-prime
rs1135471 -- 104,590,958(-) TGCTT(C/T)TGAGA utr-variant-3-prime
rs3803312 -- 104,605,478(-) GATTT(C/G)CATCT upstream-variant-2KB
rs3803313 -- 104,604,454(-) TTCCT(A/C)TGCAA synonymous-codon, reference
rs3803314 -- 104,595,081(-) CCCCA(C/T)CCAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM179 Gene

Variant ID Type Subtype PubMed ID
nsv902372 CNV Loss 21882294
nsv902373 CNV Loss 21882294
nsv470676 CNV Loss 18288195
nsv456445 CNV Loss 19166990
dgv2007n71 CNV Gain 21882294
nsv902376 CNV Gain 21882294
nsv902377 CNV Gain 21882294

Relevant External Links for TMEM179 Gene

HapMap Linkage Disequilibrium report
TMEM179

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM179 Gene

Disorders for TMEM179 Gene

No disorders were found for TMEM179 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM179 Gene

Publications for TMEM179 Gene

  1. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for TMEM179 Gene

Sources for TMEM179 Gene

Back to Top

Content