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Aliases for TMEM171 Gene

Aliases for TMEM171 Gene

  • Transmembrane Protein 171 2 3
  • Proline-Rich Protein PRP2 3
  • Prp2 3

External Ids for TMEM171 Gene

Previous GeneCards Identifiers for TMEM171 Gene

  • GC05P072454
  • GC05P067622

Summaries for TMEM171 Gene

GeneCards Summary for TMEM171 Gene

TMEM171 (Transmembrane Protein 171) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM171 Gene

Genomics for TMEM171 Gene

Regulatory Elements for TMEM171 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM171 Gene

Start:
73,114,461 bp from pter
End:
73,131,936 bp from pter
Size:
17,476 bases
Orientation:
Plus strand

Genomic View for TMEM171 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM171 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM171 Gene

Proteins for TMEM171 Gene

  • Protein details for TMEM171 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WVE6-TM171_HUMAN
    Recommended name:
    Transmembrane protein 171
    Protein Accession:
    Q8WVE6
    Secondary Accessions:
    • Q8N0S1
    • Q8TDT7

    Protein attributes for TMEM171 Gene

    Size:
    324 amino acids
    Molecular mass:
    34760 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB89327.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM171 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM171 Gene

Proteomics data for TMEM171 Gene at MOPED

Post-translational modifications for TMEM171 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM171 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM171 Gene

Domains for TMEM171 Gene

Protein Domains for TMEM171 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM171 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM171: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM171 Gene

Function for TMEM171 Gene

Gene Ontology (GO) - Molecular Function for TMEM171 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM171: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM171

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM171 Gene

Localization for TMEM171 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM171 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM171 Gene COMPARTMENTS Subcellular localization image for TMEM171 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM171 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM171: view

Pathways for TMEM171 Gene

SuperPathways for TMEM171 Gene

No Data Available

Interacting Proteins for TMEM171 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000415030%0d%0a9606.ENSP00000383820%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000415030 Q8WVE6-TM171_HUMAN for TMEM171 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for TMEM171 Gene

None

No data available for Pathways by source for TMEM171 Gene

Transcripts for TMEM171 Gene

mRNA/cDNA for TMEM171 Gene

Unigene Clusters for TMEM171 Gene

Transmembrane protein 171:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM171

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM171 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4
SP1:
SP2:

Relevant External Links for TMEM171 Gene

GeneLoc Exon Structure for
TMEM171
ECgene alternative splicing isoforms for
TMEM171

Expression for TMEM171 Gene

mRNA expression in normal human tissues for TMEM171 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM171 Gene

This gene is overexpressed in Colon - Transverse (13.7), Stomach (8.4), Thyroid (5.6), Spleen (4.8), Small Intestine - Terminal Ileum (4.8), and Kidney - Cortex (4.1).

SOURCE GeneReport for Unigene cluster for TMEM171 Gene Hs.162246

genes like me logo Genes that share expressions with TMEM171: view

In Situ Assay Products

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for TMEM171 Gene

Orthologs for TMEM171 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM171 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM171 35
  • 99.59 (n)
  • 99.69 (a)
TMEM171 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM171 35
  • 81.36 (n)
  • 79.87 (a)
TMEM171 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM171 35
  • 76.38 (n)
  • 74.61 (a)
TMEM171 36
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem171 35
  • 78.3 (n)
  • 74.77 (a)
Tmem171 16
Tmem171 36
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM171 36
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM171 36
  • 67 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem171 35
  • 79.13 (n)
  • 75.08 (a)
chicken
(Gallus gallus)
Aves TMEM171 35
  • 58.31 (n)
  • 47.91 (a)
TMEM171 36
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM171 36
  • 49 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.25760 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.19439 35
tmem171 35
  • 59.49 (n)
  • 55.5 (a)
Species with no ortholog for TMEM171:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM171 Gene

ENSEMBL:
Gene Tree for TMEM171 (if available)
TreeFam:
Gene Tree for TMEM171 (if available)

Paralogs for TMEM171 Gene

No data available for Paralogs for TMEM171 Gene

Variants for TMEM171 Gene

Sequence variations from dbSNP and Humsavar for TMEM171 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs481619 -- 73,116,775(+) ctgaa(A/G)ctcct intron-variant
rs513130 -- 73,124,512(+) TAAAA(C/T)GAGCA intron-variant
rs556535 -- 73,121,814(+) GGGCC(A/T)CAGTC intron-variant
rs570888 -- 73,126,191(+) TGATT(A/G)GCCTG intron-variant
rs586623 -- 73,129,250(-) caatg(A/G)gaaac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM171 Gene

Variant ID Type Subtype PubMed ID
nsv830344 CNV Gain+Loss 17160897

Relevant External Links for TMEM171 Gene

HapMap Linkage Disequilibrium report
TMEM171

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM171 Gene

Disorders for TMEM171 Gene

Relevant External Links for TMEM171

Human Genome Epidemiology (HuGE) Navigator
TMEM171
genes like me logo Genes that share disorders with TMEM171: view

No data available for UniProtKB/Swiss-Prot for TMEM171 Gene

Publications for TMEM171 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S. … Mitaku S. (FEBS Lett. 2002) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for TMEM171 Gene

Sources for TMEM171 Gene

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