Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM170A Gene

protein-coding   GIFtS: 46
GCID: GC16M075476

Transmembrane Protein 170A

(Previous name: transmembrane protein 170)
(Previous symbol: TMEM170)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 170A1 2
TMEM1701 2 3
Transmembrane Protein 1701 2

External Ids:    HGNC: 295771   Entrez Gene: 1244912   Ensembl: ENSG000001668227   UniProtKB: Q8WVE73   

Export aliases for TMEM170A gene to outside databases

Previous GC identifers: GC16M074039 GC16M061232


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM170A Gene:
TMEM170A (transmembrane protein 170A) is a protein-coding gene. Diseases associated with TMEM170A include coronary artery disease, and malaria. An important paralog of this gene is TMEM170B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000016.10  NT_010498.16  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM170A gene promoter:
         STAT5B   NF-1   Lmo2   CUTL1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   Arnt   Chx10   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM170A promoter sequence
   Search Chromatin IP Primers for TMEM170A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM170A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.1   Ensembl cytogenetic band:  16q23.1   HGNC cytogenetic band: 16q23.1

TMEM170A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM170A gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M075476:  view genomic region     (about GC identifiers)

Start:
75,476,952 bp from pter      End:
75,499,395 bp from pter
Size:
22,444 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: T170A_HUMAN, Q8WVE7 (See protein sequence)
Recommended Name: Transmembrane protein 170A  
Size: 144 amino acids; 15250 Da
Secondary accessions: B2R4R3 B4DPS4 D3DUK2 Q7Z6F3
Alternative splicing: 2 isoforms:  Q8WVE7-1   Q8WVE7-2   

Explore the universe of human proteins at neXtProt for TMEM170A: NX_Q8WVE7

Explore proteomics data for TMEM170A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys23
  • Glycosylation2 at Asn30, Asn36
  • Modification sites at PhosphoSitePlus

  • See TMEM170A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_660297.1  
    ENSEMBL proteins: 
     ENSP00000350230   ENSP00000454552   ENSP00000455491   ENSP00000454404   ENSP00000456509  
     ENSP00000456194   ENSP00000455938  

    TMEM170A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMEM170A
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM170A
    GenScript Custom Purified and Recombinant Proteins Services for TMEM170A
    Novus Biologicals TMEM170A Protein
    Novus Biologicals TMEM170A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM170A

    TMEM170A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM170A
    Novus Biologicals TMEM170A Antibody
    Search for Antibodies for TMEM170A at Abcam
    Cloud-Clone Corp. Antibodies for TMEM170A
    Search ThermoFisher Antibodies for TMEM170A
    Search LSBio for Antibodies for TMEM170A

    TMEM170A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM170A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM170A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM170A
    Cloud-Clone Corp. CLIAs for TMEM170A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR019334 Transmembrane_pr_170

    Graphical View of Domain Structure for InterPro Entry Q8WVE7

    ProtoNet protein and cluster: Q8WVE7

    UniProtKB/Swiss-Prot: T170A_HUMAN, Q8WVE7
    Similarity: Belongs to the TMEM170 family


    TMEM170A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 GenomeRNAi human phenotype for TMEM170A:
     Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM170A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM170A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM170A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM170A

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM170A:
    hsa-mir-375 (MIRT019829)

    Block miRNA regulation of human, mouse, rat TMEM170A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TMEM170A
    SwitchGear 3'UTR luciferase reporter plasmidTMEM170A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM170A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM170A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM170A

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM170A (see all 6)
    OriGene ORF clones in mouse, rat for TMEM170A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM170A (NM_145254)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM170A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM170A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM170A
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM170A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM170A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    T170A_HUMAN, Q8WVE7: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    TMEM170A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM170A
    Interactions:

        Search GeneGlobe Interaction Network for TMEM170A

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TMEM170A (ENSP000003502304) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IDH3BENSP000003702234STRING: ENSP00000370223
    IDH3GENSP000002179014STRING: ENSP00000217901
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM170A (T170A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM170A gene: 
    NM_145254.1  

    Unigene Cluster for TMEM170A:

    Transmembrane protein 170A
    Hs.487510  [show with all ESTs]
    Unigene Representative Sequence: BX648484
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000357613(uc002feb.3 uc002fec.3) ENST00000568559(uc002fed.1 uc002fee.1)
    ENST00000569540 ENST00000561878 ENST00000567796 ENST00000566980 ENST00000569276

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM170A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TMEM170A
    SwitchGear 3'UTR luciferase reporter plasmidTMEM170A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM170A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM170A
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM170A (see all 6)
    OriGene ORF clones in mouse, rat for TMEM170A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM170A (NM_145254)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM170A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM170A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM170A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM170A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM170A
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM170A
      QuantiFast Probe-based Assays in human, mouse, rat TMEM170A

    Additional mRNA sequence: 

    AK094930.1 AK298475.1 AK311919.1 AY302139.1 BC018082.1 BC031860.1 BX647432.1 BX648429.1 
    BX648484.1 

    16 DOTS entries:

    DT.110533  DT.99954833  DT.308494  DT.412326  DT.424679  DT.100774917  DT.120669658  DT.120669709 
    DT.95112285  DT.92432493  DT.101975064  DT.100774915  DT.102840376  DT.97784450  DT.120669650  DT.120669768 

    Selected AceView cDNA sequences (see all 163):

    BG681520 AI376622 AA702611 AA348459 BQ423692 AI917687 AI886060 AI337404 
    AA348460 BX503857 AA877133 AI890125 AA886733 BX473419 BG199544 CA950584 
    AI376117 AY302139 BQ931868 AW028583 BG535486 BG180967 CK300903 BG194813 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM170A (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d · 7e
    SP1:                                                              -                                 
    SP2:                    -     -     -     -     -           -     -                                 
    SP3:                          -     -     -     -           -     -                                 
    SP4:                          -     -     -     -                 -                                 
    SP5:                                -     -     -                 -                                 


    ECgene alternative splicing isoforms for TMEM170A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM170A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATATTCTAA
    TMEM170A Expression
    About this image


    TMEM170A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
    TMEM170A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM170A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.487510
        Custom PCR Arrays for TMEM170A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM170A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM170A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM170A
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM170A
    QuantiFast Probe-based Assays in human, mouse, rat TMEM170A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM170A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for TMEM170A gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1701 , 5 transmembrane protein 1701, 5 91.9(n)1
    95.83(a)1
      8 (58.08 cM)5
    668171  NM_025781.21  NP_080057.11 
     1118648985 
    chicken
    (Gallus gallus)
    Aves TMEM170A1 transmembrane protein 170A 77.86(n)
    86.72(a)
      770531  NM_001080880.1  NP_001074349.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    69(a)
    1 → many
    GL343751.1(19940-23310)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem170a1 transmembrane protein 170A 73.13(n)
    88.37(a)
      100135226  NM_001113923.1  NP_001107395.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem170a1 transmembrane protein 170A 59.9(n)
    66.41(a)
      393662  NM_200689.1  NP_956983.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG123411 CG12341 52.91(n)
    51.38(a)
      36137  NM_136768.2  NP_610612.1 


    ENSEMBL Gene Tree for TMEM170A (if available)
    TreeFam Gene Tree for TMEM170A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMEM170A gene
    TMEM170B2  ENSG000002617172  
    1 SIMAP similar gene for TMEM170A using alignment to 5 protein entries:     T170A_HUMAN (see all proteins):
    TMEM170B

    TMEM170A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM170A (see all 507)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1929437821,2
    --61231908(+) TGATAA/CCCAAT 1 -- int10--------
    rs1169819121,2
    F--61232031(+) TATACC/GAAAGT 1 -- int11Minor allele frequency- G:0.03NA 120
    rs1392988151,2
    --61232069(+) TAAAGA/TATCTT 1 -- int10--------
    rs424711,2
    C,F,O,H--61232082(+) GTGTGC/TCTCAA 1 -- int114Minor allele frequency- T:0.03NS EA NA 1994
    rs1844299351,2
    --61232230(+) TAGCTA/GGCTTA 1 -- int10--------
    rs781286521,2
    F--61232366(+) ACCAAA/GGCCAC 1 -- int11Minor allele frequency- G:0.05WA 118
    rs1889907731,2
    --61232584(+) CAAAAC/TATGCG 1 -- ut310--------
    rs1500166831,2
    --61232637(+) CCCCAC/GAGACA 1 -- ut310--------
    rs15401,2
    C,F,O,A--61232659(+) GCTTGA/C/GGTAAA 2 -- ut318MN EA NA CSA WA 2050
    rs4515891,2
    C,F,O,A,H--61232689(+) TAAATT/CAAATA 1 -- ut3121Minor allele frequency- C:0.12NS EA NA WA CSA 2021

    HapMap Linkage Disequilibrium report for TMEM170A (75476952 - 75499395 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TMEM170A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2714709CNV Deletion23290073
    nsv525955CNV Loss19592680
    nsv521596CNV Loss19592680
    nsv457521CNV Gain19166990
    dgv902e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM170A
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM170A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    2 diseases for TMEM170A:    
    About MalaCards
    coronary artery disease    malaria


    TMEM170A for disorders           About GeneDecksing

    Genetic Association Database (GAD): TMEM170A
    Human Genome Epidemiology (HuGE) Navigator: TMEM170A (1 document)

    Export disorders for TMEM170A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM170A gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with TMEM170A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. (PubMed id 19844255)1, 4 Dastani Z....Genest J. (Eur. J. Hum. Genet. 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. (PubMed id 23152477)1 Gertow K....Hamsten A. (Circ Cardiovasc Genet 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 124491 HGNC: 29577 AceView: LOC124491 Ensembl:ENSG00000166822 euGenes: HUgn124491
    ECgene: TMEM170A H-InvDB: TMEM170A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM170A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM170A gene:
    Search GeneIP for patents involving TMEM170A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM170A  
     OriGene qPCR primer pairs and template standards for TMEM170A   OriGene Protein Over-expression Lysate for TMEM170A  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM170A  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM170A   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM170A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM170A   OriGene Custom Protein Services for TMEM170A  

     
     
     Block miRNA regulation of human, mouse, rat TMEM170A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM170A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM170A Predesigned siRNA for gene silencing in human, mouse, rat TMEM170A
     QuantiFast Probe-based Assays in human, mouse, rat TMEM170A QuantiTect SYBR Green Assays in human, mouse, rat TMEM170A
     Custom PCR Arrays for TMEM170A Search Chromatin IP Primers for TMEM170A
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM170A  Search GeneGlobe Interaction Network for TMEM170A
     Regulatory tfbs in TMEM170A promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM170A GenScript cDNA clones with any tag delivered in your preferred vector for TMEM170A
     GenScript Custom Assay Services for TMEM170A GenScript Custom overexpressing Cell Line Services for TMEM170A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM170A (T170A)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM170A antibodies
     TMEM170A proteins
     TMEM170A lysates
     Search for Antibodies for TMEM170A at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TMEM170A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM170A
     Antibodies for TMEM170A
     ELISAs for TMEM170A
     CLIAs for TMEM170A



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM170A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM170A
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM170A
     SwitchGear Promoter luciferase reporter plasmids for TMEM170A
     Search ThermoFisher Antibodies for TMEM170A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM170A
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM170A
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM170A
     Search LSBio for Antibodies for TMEM170A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM170A gene at Home site.
    Version: 3.12.162 20 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4