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Aliases for TMEM167A Gene

Aliases for TMEM167A Gene

  • Transmembrane Protein 167A 2 3 4
  • Transmembrane Protein 167 2 3 4
  • TMEM167 3 4
  • Protein Kish-A 3

External Ids for TMEM167A Gene

Previous HGNC Symbols for TMEM167A Gene

  • TMEM167

Previous GeneCards Identifiers for TMEM167A Gene

  • GC05M082388
  • GC05M077557
  • GC05M082348

Summaries for TMEM167A Gene

GeneCards Summary for TMEM167A Gene

TMEM167A (Transmembrane Protein 167A) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TMEM167A Gene

  • Involved in the early part of the secretory pathway.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM167A Gene

Genomics for TMEM167A Gene

Regulatory Elements for TMEM167A Gene

Genomic Location for TMEM167A Gene

Start:
83,052,846 bp from pter
End:
83,077,863 bp from pter
Size:
25,018 bases
Orientation:
Minus strand

Genomic View for TMEM167A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM167A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM167A Gene

Proteins for TMEM167A Gene

  • Protein details for TMEM167A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBQ9-KISHA_HUMAN
    Recommended name:
    Protein kish-A
    Protein Accession:
    Q8TBQ9
    Secondary Accessions:
    • Q0P692

    Protein attributes for TMEM167A Gene

    Size:
    72 amino acids
    Molecular mass:
    8060 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM167A Gene

Proteomics data for TMEM167A Gene at MOPED

Post-translational modifications for TMEM167A Gene

Other Protein References for TMEM167A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM167A Gene

Domains for TMEM167A Gene

Protein Domains for TMEM167A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM167A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TBQ9

UniProtKB/Swiss-Prot:

KISHA_HUMAN :
  • Belongs to the KISH family.
Family:
  • Belongs to the KISH family.
genes like me logo Genes that share domains with TMEM167A: view

No data available for Gene Families for TMEM167A Gene

Function for TMEM167A Gene

Molecular function for TMEM167A Gene

UniProtKB/Swiss-Prot Function:
Involved in the early part of the secretory pathway.

Phenotypes for TMEM167A Gene

MGI mutant phenotypes for TMEM167A:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with TMEM167A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM167A

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM167A Gene

Localization for TMEM167A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM167A Gene

Golgi apparatus membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM167A Gene COMPARTMENTS Subcellular localization image for TMEM167A gene
Compartment Confidence
golgi apparatus 5
extracellular 3

Gene Ontology (GO) - Cellular Components for TMEM167A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005794 Golgi apparatus --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM167A: view

Pathways for TMEM167A Gene

SuperPathways for TMEM167A Gene

No Data Available

Interacting Proteins for TMEM167A Gene

Gene Ontology (GO) - Biological Process for TMEM167A Gene

None

No data available for Pathways by source for TMEM167A Gene

Transcripts for TMEM167A Gene

Unigene Clusters for TMEM167A Gene

Transmembrane protein 167A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM167A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM167A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b
SP1: -
SP2:
SP3: - - -

Relevant External Links for TMEM167A Gene

GeneLoc Exon Structure for
TMEM167A
ECgene alternative splicing isoforms for
TMEM167A

Expression for TMEM167A Gene

mRNA expression in normal human tissues for TMEM167A Gene

Protein differential expression in normal tissues for TMEM167A Gene

This gene is overexpressed in Nasal epithelium (37.2) and Bone (6.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM167A Gene

SOURCE GeneReport for Unigene cluster for TMEM167A Gene Hs.355606

genes like me logo Genes that share expressions with TMEM167A: view

Expression partners for TMEM167A Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM167A Gene

Orthologs for TMEM167A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TMEM167A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM167A 35
  • 96.3 (n)
  • 100 (a)
TMEM167A 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM167A 35
  • 97.22 (n)
  • 98.61 (a)
TMEM167A 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem167 35
  • 93.06 (n)
  • 97.22 (a)
Tmem167 16
Tmem167 36
  • 97 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC100609777 35
  • 99.07 (n)
  • 97.22 (a)
-- 36
  • 97 (a)
OneToMany
-- 36
  • 100 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Tmem167a 35
  • 93.52 (n)
  • 95.83 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 93 (a)
OneToMany
-- 36
  • 97 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM167A 36
  • 94 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM167A 35
  • 84.72 (n)
  • 95.83 (a)
TMEM167A 36
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM167A 36
  • 93 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.6388 35
tmem167a 35
  • 81.94 (n)
  • 87.5 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15832 35
zebrafish
(Danio rerio)
Actinopterygii tmem167a 35
  • 75.93 (n)
  • 90.28 (a)
wufa97d03 35
tmem167a 36
  • 41 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5180 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002087 35
  • 64.29 (n)
  • 77.14 (a)
fruit fly
(Drosophila melanogaster)
Insecta ksh 35
  • 65.24 (n)
  • 74.29 (a)
ksh 36
  • 72 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes KSH1 36
  • 63 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.7895 35
bread mold
(Neurospora crassa)
Ascomycetes NCU03465 35
  • 62.05 (n)
  • 70.77 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 78 (a)
OneToOne
Species with no ortholog for TMEM167A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM167A Gene

ENSEMBL:
Gene Tree for TMEM167A (if available)
TreeFam:
Gene Tree for TMEM167A (if available)

Paralogs for TMEM167A Gene

(1) SIMAP similar genes for TMEM167A Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for TMEM167A Gene

genes like me logo Genes that share paralogs with TMEM167A: view

No data available for Paralogs for TMEM167A Gene

Variants for TMEM167A Gene

Sequence variations from dbSNP and Humsavar for TMEM167A Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs1583 -- 83,052,403(-) AGCAT(A/T)GTCCA downstream-variant-500B
rs7891 -- 83,053,558(-) ACTAC(C/T)CAAGG utr-variant-3-prime
rs27493 -- 83,054,372(-) ATTGG(C/T)TTCAG utr-variant-3-prime
rs255561 -- 83,054,991(-) ACCAC(G/T)GAATC utr-variant-3-prime
rs1044363 -- 83,053,123(-) TACCA(A/G)CATTG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for TMEM167A Gene

Variant ID Type Subtype PubMed ID
nsv882242 CNV Loss 21882294
nsv511108 CNV Complex 20534489

Relevant External Links for TMEM167A Gene

HapMap Linkage Disequilibrium report
TMEM167A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM167A Gene

Disorders for TMEM167A Gene

Relevant External Links for TMEM167A

Genetic Association Database (GAD)
TMEM167A
Human Genome Epidemiology (HuGE) Navigator
TMEM167A

No disorders were found for TMEM167A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for TMEM167A Gene

Publications for TMEM167A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Phenylmethanesulfonyl fluoride elicits and intensifies the clinical expression of neuropathic insults. (PMID: 1316117) Moretto A. … Lotti M. (Arch. Toxicol. 1992) 2 3
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for TMEM167A Gene

Sources for TMEM167A Gene

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