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Aliases for TMEM167A Gene

Aliases for TMEM167A Gene

  • Transmembrane Protein 167A 2 3 4
  • Transmembrane Protein 167 2 3 4
  • TMEM167 3 4
  • Protein Kish-A 3

External Ids for TMEM167A Gene

Previous Symbols for TMEM167A Gene

  • TMEM167

Summaries for TMEM167A Gene

GeneCards Summary for TMEM167A Gene

TMEM167A (Transmembrane Protein 167A) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TMEM167A Gene

  • Involved in the early part of the secretory pathway.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM167A Gene

Genomics for TMEM167A Gene

Genomic Location for TMEM167A Gene

Start:
83,052,846 bp from pter
End:
83,077,863 bp from pter
Size:
25,018 bases
Orientation:
Minus strand

Genomic View for TMEM167A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM167A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM167A Gene

Regulatory Elements for TMEM167A Gene

Proteins for TMEM167A Gene

  • Protein details for TMEM167A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBQ9-KISHA_HUMAN
    Recommended name:
    Protein kish-A
    Protein Accession:
    Q8TBQ9
    Secondary Accessions:
    • Q0P692

    Protein attributes for TMEM167A Gene

    Size:
    72 amino acids
    Molecular mass:
    8060 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM167A Gene

Proteomics data for TMEM167A Gene at MOPED

Post-translational modifications for TMEM167A Gene

Other Protein References for TMEM167A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM167A Gene

Domains for TMEM167A Gene

Protein Domains for TMEM167A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

KISHA_HUMAN
Family:
  • Belongs to the KISH family.:
    • Q8TBQ9
genes like me logo Genes that share domains with TMEM167A: view

No data available for Gene Families for TMEM167A Gene

Function for TMEM167A Gene

Molecular function for TMEM167A Gene

UniProtKB/Swiss-Prot Function: Involved in the early part of the secretory pathway.

Phenotypes for TMEM167A Gene

MGI mutant phenotypes for TMEM167A:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with TMEM167A: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM167A Gene

Localization for TMEM167A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM167A Gene

Golgi apparatus membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM167A Gene COMPARTMENTS Subcellular localization image for TMEM167A gene
Compartment Confidence
golgi apparatus 5
extracellular 3

Gene Ontology (GO) - Cellular Components for TMEM167A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005794 Golgi apparatus --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM167A: view

Pathways for TMEM167A Gene

SuperPathways for TMEM167A Gene

No Data Available

Interacting Proteins for TMEM167A Gene

Gene Ontology (GO) - Biological Process for TMEM167A Gene

None

No data available for Pathways by source for TMEM167A Gene

Transcripts for TMEM167A Gene

Unigene Clusters for TMEM167A Gene

Transmembrane protein 167A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM167A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b
SP1: -
SP2:
SP3: - - -

Relevant External Links for TMEM167A Gene

GeneLoc Exon Structure for
TMEM167A
ECgene alternative splicing isoforms for
TMEM167A

Expression for TMEM167A Gene

mRNA expression in normal human tissues for TMEM167A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM167A Gene

SOURCE GeneReport for Unigene cluster for TMEM167A Gene Hs.355606

genes like me logo Genes that share expressions with TMEM167A: view

Orthologs for TMEM167A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TMEM167A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 97 (a)
OneToMany
-- 37
  • 100 (a)
OneToMany
LOC100609777 36
  • 99.07 (n)
  • 97.22 (a)
cow
(Bos Taurus)
Mammalia TMEM167A 36
  • 96.3 (n)
  • 100 (a)
TMEM167A 37
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM167A 36
  • 97.22 (n)
  • 98.61 (a)
TMEM167A 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem167 36
  • 93.06 (n)
  • 97.22 (a)
Tmem167 16
Tmem167 37
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 93 (a)
OneToMany
-- 37
  • 97 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM167A 37
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem167a 36
  • 93.52 (n)
  • 95.83 (a)
chicken
(Gallus gallus)
Aves TMEM167A 36
  • 84.72 (n)
  • 95.83 (a)
TMEM167A 37
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM167A 37
  • 93 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.15832 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.6388 36
tmem167a 36
  • 81.94 (n)
  • 87.5 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5180 36
zebrafish
(Danio rerio)
Actinopterygii tmem167a 36
  • 75.93 (n)
  • 90.28 (a)
tmem167a 37
  • 41 (a)
OneToOne
wufa97d03 36
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002087 36
  • 64.29 (n)
  • 77.14 (a)
fruit fly
(Drosophila melanogaster)
Insecta ksh 36
  • 65.24 (n)
  • 74.29 (a)
ksh 37
  • 72 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes KSH1 37
  • 63 (a)
OneToOne
bread mold
(Neurospora crassa)
Ascomycetes NCU03465 36
  • 62.05 (n)
  • 70.77 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.7895 36
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 78 (a)
OneToOne
Species with no ortholog for TMEM167A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM167A Gene

ENSEMBL:
Gene Tree for TMEM167A (if available)
TreeFam:
Gene Tree for TMEM167A (if available)

Paralogs for TMEM167A Gene

Selected SIMAP similar genes for TMEM167A Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for TMEM167A Gene

genes like me logo Genes that share paralogs with TMEM167A: view

No data available for Paralogs for TMEM167A Gene

Variants for TMEM167A Gene

Sequence variations from dbSNP and Humsavar for TMEM167A Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs1583 -- 83,052,403(-) AGCAT(A/T)GTCCA downstream-variant-500B
rs7891 -- 83,053,558(-) ACTAC(C/T)CAAGG utr-variant-3-prime
rs27493 -- 83,054,372(-) ATTGG(C/T)TTCAG utr-variant-3-prime
rs255561 -- 83,054,991(-) ACCAC(G/T)GAATC utr-variant-3-prime
rs1044363 -- 83,053,123(-) TACCA(A/G)CATTG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for TMEM167A Gene

Variant ID Type Subtype PubMed ID
nsv882242 CNV Loss 21882294
nsv511108 CNV Complex 20534489

Relevant External Links for TMEM167A Gene

HapMap Linkage Disequilibrium report
TMEM167A

Disorders for TMEM167A Gene

Relevant External Links for TMEM167A

Genetic Association Database (GAD)
TMEM167A
Human Genome Epidemiology (HuGE) Navigator
TMEM167A
genes like me logo Genes that share disorders with TMEM167A: view

No data available for UniProtKB/Swiss-Prot for TMEM167A Gene

Publications for TMEM167A Gene

  1. Phenylmethanesulfonyl fluoride elicits and intensifies the clinical expression of neuropathic insults. (PMID: 1316117) Moretto A. … Lotti M. (Arch. Toxicol. 1992) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PMID: 21085059) Israni A. … Oetting W.S. (Transplantation 2010) 49

Products for TMEM167A Gene

Sources for TMEM167A Gene

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