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Aliases for TMEM161B Gene

Aliases for TMEM161B Gene

  • Transmembrane Protein 161B 2 3
  • FLB3342 3
  • PRO1313 3

External Ids for TMEM161B Gene

Summaries for TMEM161B Gene

GeneCards Summary for TMEM161B Gene

TMEM161B (Transmembrane Protein 161B) is a Protein Coding gene. An important paralog of this gene is TMEM161A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM161B Gene

Genomics for TMEM161B Gene

Genomic Location for TMEM161B Gene

Start:
88,189,633 bp from pter
End:
88,269,476 bp from pter
Size:
79,844 bases
Orientation:
Minus strand

Genomic View for TMEM161B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM161B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM161B Gene

Regulatory Elements for TMEM161B Gene

Proteins for TMEM161B Gene

  • Protein details for TMEM161B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NDZ6-T161B_HUMAN
    Recommended name:
    Transmembrane protein 161B
    Protein Accession:
    Q8NDZ6
    Secondary Accessions:
    • Q5CZH7
    • Q6UWQ6

    Protein attributes for TMEM161B Gene

    Size:
    487 amino acids
    Molecular mass:
    55482 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM161B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM161B Gene

Proteomics data for TMEM161B Gene at MOPED

Post-translational modifications for TMEM161B Gene

  • Glycosylation at Asn34, Asn135, and Asn203

No data available for DME Specific Peptides for TMEM161B Gene

Domains for TMEM161B Gene

Protein Domains for TMEM161B Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

T161B_HUMAN
Family:
  • Belongs to the TMEM161 family.:
    • Q8NDZ6
genes like me logo Genes that share domains with TMEM161B: view

No data available for Gene Families for TMEM161B Gene

Function for TMEM161B Gene

Gene Ontology (GO) - Molecular Function for TMEM161B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
genes like me logo Genes that share ontologies with TMEM161B: view

Phenotypes for TMEM161B Gene

MGI mutant phenotypes for TMEM161B:
inferred from 1 alleles
GenomeRNAi human phenotypes for TMEM161B:
genes like me logo Genes that share phenotypes with TMEM161B: view

miRNA for TMEM161B Gene

miRTarBase miRNAs that target TMEM161B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM161B Gene

Localization for TMEM161B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM161B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM161B Gene COMPARTMENTS Subcellular localization image for TMEM161B gene
Compartment Confidence
plasma membrane 2

Gene Ontology (GO) - Cellular Components for TMEM161B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM161B: view

Pathways for TMEM161B Gene

SuperPathways for TMEM161B Gene

No Data Available

Interacting Proteins for TMEM161B Gene

Gene Ontology (GO) - Biological Process for TMEM161B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015074 DNA integration --
genes like me logo Genes that share ontologies with TMEM161B: view

No data available for Pathways by source for TMEM161B Gene

Transcripts for TMEM161B Gene

Unigene Clusters for TMEM161B Gene

Transmembrane protein 161B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM161B Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c
SP1: - -
SP2: - - -
SP3:
SP4:
SP5:

Relevant External Links for TMEM161B Gene

GeneLoc Exon Structure for
TMEM161B
ECgene alternative splicing isoforms for
TMEM161B

Expression for TMEM161B Gene

mRNA expression in normal human tissues for TMEM161B Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for TMEM161B Gene

SOURCE GeneReport for Unigene cluster for TMEM161B Gene Hs.379972

genes like me logo Genes that share expressions with TMEM161B: view

Orthologs for TMEM161B Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM161B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM161B 36
  • 99.79 (n)
  • 100 (a)
TMEM161B 37
  • 88 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM161B 36
  • 95 (n)
  • 97.13 (a)
TMEM161B 37
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM161B 36
  • 95.89 (n)
  • 97.74 (a)
TMEM161B 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem161b 36
  • 91.31 (n)
  • 95.07 (a)
Tmem161b 16
Tmem161b 37
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM161B 37
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM161B 37
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem161b 36
  • 91.3 (n)
  • 95.13 (a)
chicken
(Gallus gallus)
Aves TMEM161B 36
  • 83.54 (n)
  • 89.3 (a)
TMEM161B 37
  • 90 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM161B 37
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.15030 36
tmem161b 36
  • 78.14 (n)
  • 84.95 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6252 36
zebrafish
(Danio rerio)
Actinopterygii tmem161b 36
  • 69.44 (n)
  • 77.96 (a)
tmem161b 37
  • 77 (a)
OneToOne
wufc31d04 36
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004945 36
  • 50.41 (n)
  • 44.63 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7638 36
  • 48.87 (n)
  • 41.86 (a)
CG7638 37
  • 40 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y87G2A.13 36
  • 42.73 (n)
  • 29.75 (a)
Y87G2A.13 37
  • 27 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 41 (a)
OneToMany
Species with no ortholog for TMEM161B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM161B Gene

ENSEMBL:
Gene Tree for TMEM161B (if available)
TreeFam:
Gene Tree for TMEM161B (if available)

Paralogs for TMEM161B Gene

Paralogs for TMEM161B Gene

Selected SIMAP similar genes for TMEM161B Gene using alignment to 8 proteins:

Pseudogenes.org Pseudogenes for TMEM161B Gene

genes like me logo Genes that share paralogs with TMEM161B: view

Variants for TMEM161B Gene

Sequence variations from dbSNP and Humsavar for TMEM161B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs33698 -- 88,259,575(-) TCTTA(A/G)GCCTG intron-variant
rs33699 -- 88,195,728(-) AAACA(A/G)TAAAA intron-variant, utr-variant-3-prime, nc-transcript-variant
rs33700 -- 88,195,091(+) AAAGA(C/T)TCTGA intron-variant, downstream-variant-500B
rs33701 -- 88,194,959(+) TTGAA(C/T)GTTTC intron-variant, downstream-variant-500B
rs33702 -- 88,194,847(+) GAAAA(A/G)ACAAA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TMEM161B Gene

Variant ID Type Subtype PubMed ID
nsv830384 CNV Gain 17160897
nsv830385 CNV Gain 17160897

Relevant External Links for TMEM161B Gene

HapMap Linkage Disequilibrium report
TMEM161B

Disorders for TMEM161B Gene

Relevant External Links for TMEM161B

Genetic Association Database (GAD)
TMEM161B
Human Genome Epidemiology (HuGE) Navigator
TMEM161B
genes like me logo Genes that share disorders with TMEM161B: view

No data available for UniProtKB/Swiss-Prot for TMEM161B Gene

Publications for TMEM161B Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  5. Genetic loci for retinal arteriolar microcirculation. (PMID: 23776548) Sim X. … Wong T.Y. (PLoS ONE 2013) 3

Products for TMEM161B Gene

  • antibodies-online peptides for TMEM161B
  • antibodies-online antibodies for TMEM161B
  • antibodies-online kits for TMEM161B

Sources for TMEM161B Gene

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