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Aliases for TMEM160 Gene

Aliases for TMEM160 Gene

  • Transmembrane Protein 160 2 3 5

External Ids for TMEM160 Gene

Previous GeneCards Identifiers for TMEM160 Gene

  • GC19M052242
  • GC19M047549
  • GC19M043973

Summaries for TMEM160 Gene

GeneCards Summary for TMEM160 Gene

TMEM160 (Transmembrane Protein 160) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM160 Gene

Genomics for TMEM160 Gene

Regulatory Elements for TMEM160 Gene

Enhancers for TMEM160 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G047093 2 FANTOM5 Ensembl ENCODE dbSUPER 11.9 -48.2 -48212 7.6 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 MCM3 SP3 NFYC TMEM160 SAE1 PNMA8A GC19P047078
GH19G046859 2.1 FANTOM5 Ensembl ENCODE dbSUPER 10.7 +185.4 185350 8.5 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF263 SP3 NFYC ZC3H4 ARHGAP35 SLC1A5 TMEM160 CCDC9 EHD2 SAE1 AP2S1 PNMA8A PNMA8B
GH19G047105 1.9 FANTOM5 ENCODE dbSUPER 11.4 -61.5 -61513 9.2 MLX CREB3L1 AGO1 FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF263 SP3 C5AR2 PRKD2 DHX34 ZC3H4 CCDC9 SNORD23 TMEM160 PPP5D1 C5AR1 ENSG00000268746
GH19G046983 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.4 +63.7 63679 2.5 HNRNPUL1 PKNOX1 FOXA2 ATF1 MLX ARID4B SIN3A DMAP1 ZNF48 YY1 ARHGAP35 TMEM160 AP2S1 FKRP STRN4 ZC3H4 C5AR1 DHX34 CCDC9 GC19P047005
GH19G046980 1.6 Ensembl ENCODE dbSUPER 11.1 +66.7 66713 2.2 HDGF CREB3L1 AGO1 SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF143 ZNF207 ARHGAP35 NOP53-AS1 ZC3H4 TMEM160 GC19P047005 GC19P046965 PIR46184
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TMEM160 on UCSC Golden Path with GeneCards custom track

Promoters for TMEM160 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000110493 284 1801 HDGF PKNOX1 FOXA2 CREB3L1 ARNT AGO1 WRNIP1 ARID4B SIN3A DMAP1

Genomic Location for TMEM160 Gene

Chromosome:
19
Start:
47,045,907 bp from pter
End:
47,048,784 bp from pter
Size:
2,878 bases
Orientation:
Minus strand

Genomic View for TMEM160 Gene

Genes around TMEM160 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM160 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM160 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM160 Gene

Proteins for TMEM160 Gene

  • Protein details for TMEM160 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX00-TM160_HUMAN
    Recommended name:
    Transmembrane protein 160
    Protein Accession:
    Q9NX00
    Secondary Accessions:
    • Q9BU41

    Protein attributes for TMEM160 Gene

    Size:
    188 amino acids
    Molecular mass:
    19658 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM160 Gene

Post-translational modifications for TMEM160 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM160 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM160 Gene

Domains & Families for TMEM160 Gene

Protein Domains for TMEM160 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM160 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NX00

UniProtKB/Swiss-Prot:

TM160_HUMAN :
  • Belongs to the TMEM160 family.
Family:
  • Belongs to the TMEM160 family.
genes like me logo Genes that share domains with TMEM160: view

No data available for Gene Families for TMEM160 Gene

Function for TMEM160 Gene

genes like me logo Genes that share phenotypes with TMEM160: view

Animal Model Products

CRISPR Products

miRNA for TMEM160 Gene

miRTarBase miRNAs that target TMEM160

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM160 Gene

Localization for TMEM160 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM160 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM160 gene
Compartment Confidence
mitochondrion 3
peroxisome 1
nucleus 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM160: view

Pathways & Interactions for TMEM160 Gene

SuperPathways for TMEM160 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMEM160 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM160 Gene

Drugs & Compounds for TMEM160 Gene

No Compound Related Data Available

Transcripts for TMEM160 Gene

mRNA/cDNA for TMEM160 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(75) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM160 Gene

Transmembrane protein 160:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM160 Gene

No ASD Table

Relevant External Links for TMEM160 Gene

GeneLoc Exon Structure for
TMEM160
ECgene alternative splicing isoforms for
TMEM160

Expression for TMEM160 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMEM160 Gene

Protein differential expression in normal tissues from HIPED for TMEM160 Gene

This gene is overexpressed in Nasal epithelium (64.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TMEM160 Gene



Protein tissue co-expression partners for TMEM160 Gene

NURSA nuclear receptor signaling pathways regulating expression of TMEM160 Gene:

TMEM160

SOURCE GeneReport for Unigene cluster for TMEM160 Gene:

Hs.105606

Evidence on tissue expression from TISSUES for TMEM160 Gene

  • Lung(4.1)
genes like me logo Genes that share expression patterns with TMEM160: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM160 Gene

Orthologs for TMEM160 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM160 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM160 34 35
  • 99.29 (n)
dog
(Canis familiaris)
Mammalia TMEM160 34 35
  • 89.18 (n)
cow
(Bos Taurus)
Mammalia TMEM160 34 35
  • 88.3 (n)
rat
(Rattus norvegicus)
Mammalia Tmem160 34
  • 85.11 (n)
mouse
(Mus musculus)
Mammalia Tmem160 34 16 35
  • 84.4 (n)
oppossum
(Monodelphis domestica)
Mammalia TMEM160 35
  • 68 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii tmem160 34 35
  • 58.52 (n)
Dr.17783 34
Species where no ortholog for TMEM160 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM160 Gene

ENSEMBL:
Gene Tree for TMEM160 (if available)
TreeFam:
Gene Tree for TMEM160 (if available)

Paralogs for TMEM160 Gene

Pseudogenes.org Pseudogenes for TMEM160 Gene

genes like me logo Genes that share paralogs with TMEM160: view

No data available for Paralogs for TMEM160 Gene

Variants for TMEM160 Gene

Sequence variations from dbSNP and Humsavar for TMEM160 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000184865 -- 47,047,148(+) GAGGT(G/T)GCAGC intron-variant
rs1000700398 -- 47,049,447(+) CTAAC(C/T)CATTC upstream-variant-2KB
rs1000767991 -- 47,048,475(+) GCGAA(A/G)CCCCG upstream-variant-2KB, reference, missense
rs1000980952 -- 47,048,125(+) CCTCT(C/T)CCCAC intron-variant, upstream-variant-2KB
rs1001112783 -- 47,049,726(+) TGAGG(C/T)GGGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TMEM160 Gene

Variant ID Type Subtype PubMed ID
nsv2512 CNV insertion 18451855

Variation tolerance for TMEM160 Gene

Gene Damage Index Score: 4.05; 60.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM160 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM160

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM160 Gene

Disorders for TMEM160 Gene

Relevant External Links for TMEM160

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM160

No disorders were found for TMEM160 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM160 Gene

Publications for TMEM160 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64

Products for TMEM160 Gene

Sources for TMEM160 Gene

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