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TMEM159 Gene

protein-coding   GIFtS: 47
GCID: GC16P021169

Transmembrane Protein 159

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 1591 2 3
PROMETHIN2
promethin2

External Ids:    HGNC: 301361   Entrez Gene: 571462   Ensembl: ENSG000000116387   OMIM: 6113045   UniProtKB: Q96B963   

Export aliases for TMEM159 gene to outside databases

Previous GC identifers: GC16P021078 GC16P019705


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM159 Gene:
TMEM159 (transmembrane protein 159) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_187260.1  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM159 gene promoter:
         p53   Pax-6   Brachyury   HNF-3beta   POU2F1   POU2F1a   POU2F1b   IRF-7A   PPAR-gamma2   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM159 promoter sequence
   Search Chromatin IP Primers for TMEM159

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM159


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12   Ensembl cytogenetic band:  16p12.3   HGNC cytogenetic band: 16p12.2

TMEM159 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM159 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P021169:  view genomic region     (about GC identifiers)

Start:
21,169,698 bp from pter      End:
21,191,937 bp from pter
Size:
22,240 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TM159_HUMAN, Q96B96 (See protein sequence)
Recommended Name: Promethin  
Size: 161 amino acids; 17522 Da
Secondary accessions: A6NMA9 O00323

Explore the universe of human proteins at neXtProt for TMEM159: NX_Q96B96

Explore proteomics data for TMEM159 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn29, Asn141
  • Modification sites at PhosphoSitePlus

  • See TMEM159 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065155.3  
    ENSEMBL proteins: 
     ENSP00000461828   ENSP00000233047   ENSP00000459481   ENSP00000261388   ENSP00000409879  
     ENSP00000460687   ENSP00000461826   ENSP00000460102  

    TMEM159 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for TMEM159
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    Novus Biologicals TMEM159 Protein
    Novus Biologicals TMEM159 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM159

     
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    antibodies-online proteins for TMEM159 

     
    antibodies-online peptides for TMEM159

    TMEM159 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Search for Antibodies for TMEM159 at Abcam
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    Search antibodies-online for antibodies for TMEM159 

    TMEM159 Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM159
    Cloud-Clone Corp. CLIAs for TMEM159
    Search eBioscience for ELISAs for TMEM159 
    antibodies-online kits for TMEM159 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q96B96

    UniProtKB/Swiss-Prot: TM159_HUMAN, Q96B96
    Similarity: Belongs to the TMEM159 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TMEM159

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM159:
    hsa-mir-335-5p (MIRT018893)

    Block miRNA regulation of human, mouse, rat TMEM159 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM159 (see all 13):
    hsa-miR-301b hsa-miR-519c-3p hsa-miR-301a hsa-miR-519a hsa-miR-3666 hsa-miR-519b-3p hsa-miR-421 hsa-miR-19b
    SwitchGear 3'UTR luciferase reporter plasmidTMEM159 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM159
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM159

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for TMEM159

    Clone
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    OriGene clones in human, mouse for TMEM159 (see all 6)
    OriGene ORF clones in mouse, rat for TMEM159
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM159 (NM_020422)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM159
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM159

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM159 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM159


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM159_HUMAN, Q96B96: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM159           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM159
    Interactions:

        Search GeneGlobe Interaction Network for TMEM159

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for TMEM159 (Q96B962, 3 ENSP000002330474) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PARP2Q9UGN52, 3, ENSP000002504164MINT-8202219 I2D: score=1 STRING: ENSP00000250416
    CACFD1Q9UGQ23I2D: score=1 
    PSMA1P257863I2D: score=1 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM159 (TM159)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM159 gene: 
    NM_020422.4  

    Unigene Cluster for TMEM159:

    Transmembrane protein 159
    Hs.258212  [show with all ESTs]
    Unigene Representative Sequence: NM_020422
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000573487 ENST00000233047(uc002dig.4 uc010vbf.2 uc002dih.4)
    ENST00000572258 ENST00000574092 ENST00000261388(uc002dif.4) ENST00000451578
    ENST00000572599 ENST00000577162 ENST00000573688
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM159 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM159 (see all 13):
    hsa-miR-301b hsa-miR-519c-3p hsa-miR-301a hsa-miR-519a hsa-miR-3666 hsa-miR-519b-3p hsa-miR-421 hsa-miR-19b
    SwitchGear 3'UTR luciferase reporter plasmidTMEM159 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM159
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM159
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM159 (see all 6)
    OriGene ORF clones in mouse, rat for TMEM159
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM159 (NM_020422)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM159
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM159
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM159
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM159
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM159
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM159
      QuantiFast Probe-based Assays in human, mouse, rat TMEM159

    Additional mRNA sequence: 

    AF070596.1 AK074667.1 AK293557.1 AY212918.1 BC015812.1 BX647512.1 

    8 DOTS entries:

    DT.114285  DT.100788617  DT.91737345  DT.100788620  DT.91737361  DT.100788619  DT.100732754  DT.91737359 

    Selected AceView cDNA sequences (see all 151):

    AA905252 BU947538 BX282506 BM924035 AA953509 CB158506 AI291803 AA947241 
    AW405043 Z38799 BF940501 AA804885 BF449015 BU789678 BQ953550 BX339274 
    AA807413 AW575176 AI937296 BE464166 AW027752 BX390573 BX399988 BE892932 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM159 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f
    SP1:                          -                                   -                                       
    SP2:                          -           -                       -                                       
    SP3:                                      -                       -                                       
    SP4:                                                                                                      
    SP5:                          -           -                 -     -                                       


    ECgene alternative splicing isoforms for TMEM159

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM159 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAAACAAAA
    TMEM159 Expression
    About this image


    TMEM159 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass
     
     Ovary (Reproductive System)
     
     Esophagus (Gastrointestinal Tract)
    TMEM159 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM159 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.258212

    UniProtKB/Swiss-Prot: TM159_HUMAN, Q96B96
    Tissue specificity: Expressed at high levels in the heart and skeletal muscle. Expressed at low levels in kidney,
    small intestine, lung and liver

        Custom PCR Arrays for TMEM159
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    QuantiFast Probe-based Assays in human, mouse, rat TMEM159
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM159

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM159 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1591 , 5 transmembrane protein 1591, 5 79.54(n)1
    71.52(a)1
      7 (64.37 cM)5
    2338061  NM_145586.11  NP_663561.11 
     1201023765 
    chicken
    (Gallus gallus)
    Aves TMEM1591 transmembrane protein 159 58.84(n)
    48.48(a)
      427005  XM_424607.4  XP_424607.3 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM1596
    transmembrane protein 159
    39(a)
    1 ↔ 1
    GL343402.1(908639-917393)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004869251 promethin-A-like 56.98(n)
    47.97(a)
      100486925  XM_002931959.2  XP_002932005.1 


    ENSEMBL Gene Tree for TMEM159 (if available)
    TreeFam Gene Tree for TMEM159 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM159 (see all 382)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1417539161,2
    C--21172805(+) ATCTTC/TCAGGC 1 -- int10--------
    rs1179188351,2
    C,F--21172885(+) GCACAC/TAATAC 1 -- int11Minor allele frequency- T:0.02NA 120
    rs1173003291,2
    C,F--21172889(+) ACAATA/GCTTCC 1 -- int11Minor allele frequency- G:0.02NA 120
    rs1500478721,2
    C--21172947(+) ATGCAA/GTTCTT 1 -- int10--------
    rs1881821411,2
    C--21173106(+) GGTCCC/GATAGA 1 -- int10--------
    rs125973301,2
    C,F,H--21173117(+) aatatG/Aatgtg 1 -- int17Minor allele frequency- A:0.10NS EA NA 662
    rs123860361,2
    C,F,H--21173137(+) tgtaaC/Tttaga 1 -- int122Minor allele frequency- T:0.44NS EA NA WA CSA 2344
    rs1929809911,2
    --21173208(+) GCATAG/TTGGCT 1 -- int10--------
    rs1453993671,2
    C--21173325(+) ATTACC/TAAAAT 1 -- int10--------
    rs1829127431,2
    --21173409(+) GAGGCA/GGAGGT 1 -- int10--------

    HapMap Linkage Disequilibrium report for TMEM159 (21169698 - 21191937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TMEM159:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv436835CNV Insertion17901297
    esv33128CNV Loss17666407
    esv33636CNV Loss17666407
    nsv457444CNV Loss19166990
    nsv833166CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM159
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM159

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611304    OMIM disorders: --


    Find genes that share disorders with TMEM159           About GenesLikeMe

    Genetic Association Database (GAD): TMEM159
    Human Genome Epidemiology (HuGE) Navigator: TMEM159 (1 document)

    Export disorders for TMEM159 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM159 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with TMEM159)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of promethin and PGLP as two novel up-regulated genes in PPARgamma1-induced adipogenic mouse liver. (PubMed id 15589683)1, 2, 3 Yu S.... Reddy J.K. (Biochimie 2004)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (Genome Res. 1997)
    4. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)
    5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. Large-scale identification of human genes implicated in epidermal barrier function. (PubMed id 17562024)1 Toulza E.... Guerrin M. (Genome Biol. 2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57146 HGNC: 30136 AceView: LOC57146 Ensembl:ENSG00000011638 euGenes: HUgn57146
    ECgene: TMEM159 H-InvDB: TMEM159

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM159 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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