Aliases for TMEM158 Gene
Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]
GeneCards Summary for TMEM158 Gene
TMEM158 (Transmembrane Protein 158 (Gene/Pseudogene)) is a Protein Coding gene. Diseases associated with TMEM158 include Brain Injury. Gene Ontology (GO) annotations related to this gene include peptide binding.
UniProtKB/Swiss-Prot for TMEM158 Gene
Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide.