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Aliases for TMEM155 Gene

Aliases for TMEM155 Gene

  • Transmembrane Protein 155 2 3 5

External Ids for TMEM155 Gene

Previous GeneCards Identifiers for TMEM155 Gene

  • GC04M122899
  • GC04M122680
  • GC04M118407

Summaries for TMEM155 Gene

GeneCards Summary for TMEM155 Gene

TMEM155 (Transmembrane Protein 155) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM155 Gene

Genomics for TMEM155 Gene

Regulatory Elements for TMEM155 Gene

Enhancers for TMEM155 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F121788 1.1 Ensembl ENCODE 24.1 -24.5 -24528 3.3 PKNOX1 ATF1 ARNT SIN3A FEZF1 GATA2 FOS JUNB NCOA1 REST TMEM155 PP12613 CCNA2 BBS7 EXOSC9
GH04F121783 0.5 Ensembl ENCODE 12.5 -19.1 -19112 3.6 PKNOX1 JUN SIN3A CEBPG ZNF316 EED RCOR1 TRIM24 EGR2 JUNB TMEM155 PP12613 BBS7 EXOSC9
GH04F121794 1 Ensembl ENCODE 11.7 -29.7 -29749 2.5 ATF1 PKNOX1 ARNT ZFP64 ZNF2 GATA2 KLF7 NFYC JUNB NCOA1 TMEM155 PP12613 CCNA2 BBS7 EXOSC9
GH04F121727 0.8 Ensembl ENCODE 11.4 +37.7 37652 2.3 JUND ZFP3 BHLHE40 CEBPB FOS KDM1A MAFK ANXA5 TMEM155 PP12613 QRFPR
GH04F121717 0.5 ENCODE 11.4 +48.0 48002 1.6 RAD21 NR2F2 ANXA5 PP12613 TMEM155
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TMEM155 on UCSC Golden Path with GeneCards custom track

Promoters for TMEM155 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001434745 1041 1599 MAZ RNF2 CBX2 SP2 ZBTB8A HIC1 GLIS2 ZFHX2 ZBTB26 EZH2

Genomic Location for TMEM155 Gene

Chromosome:
4
Start:
121,758,930 bp from pter
End:
121,766,042 bp from pter
Size:
7,113 bases
Orientation:
Minus strand

Genomic View for TMEM155 Gene

Genes around TMEM155 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM155 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM155 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM155 Gene

Proteins for TMEM155 Gene

  • Protein details for TMEM155 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4W5P6-TM155_HUMAN
    Recommended name:
    Protein TMEM155
    Protein Accession:
    Q4W5P6
    Secondary Accessions:
    • D3DNW9
    • Q96NI2

    Protein attributes for TMEM155 Gene

    Size:
    130 amino acids
    Molecular mass:
    14221 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM155 Gene

Post-translational modifications for TMEM155 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMEM155 Gene

Domains & Families for TMEM155 Gene

Protein Domains for TMEM155 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TMEM155 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM155: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM155 Gene

Function for TMEM155 Gene

Animal Model Products

miRNA for TMEM155 Gene

miRTarBase miRNAs that target TMEM155

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM155 Gene

Localization for TMEM155 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM155 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM155 Gene COMPARTMENTS Subcellular localization image for TMEM155 gene
Compartment Confidence
extracellular 5

Gene Ontology (GO) - Cellular Components for TMEM155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with TMEM155: view

Pathways & Interactions for TMEM155 Gene

SuperPathways for TMEM155 Gene

No Data Available

Interacting Proteins for TMEM155 Gene

Selected Interacting proteins: Q4W5P6-TM155_HUMAN for TMEM155 Gene via IID

Symbol External ID(s) Details
LMBR1
TMEM259

Gene Ontology (GO) - Biological Process for TMEM155 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM155 Gene

Transcripts for TMEM155 Gene

Unigene Clusters for TMEM155 Gene

Transmembrane protein 155:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM155 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
SP1: - -
SP2:

Relevant External Links for TMEM155 Gene

GeneLoc Exon Structure for
TMEM155
ECgene alternative splicing isoforms for
TMEM155

Expression for TMEM155 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TMEM155 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM155 Gene

This gene is overexpressed in Brain - Cortex (x13.9), Brain - Frontal Cortex (BA9) (x13.3), and Brain - Anterior cingulate cortex (BA24) (x12.6).

NURSA nuclear receptor signaling pathways regulating expression of TMEM155 Gene:

TMEM155

SOURCE GeneReport for Unigene cluster for TMEM155 Gene:

Hs.27524
genes like me logo Genes that share expression patterns with TMEM155: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TMEM155 Gene

Orthologs for TMEM155 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM155 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM155 34
  • 98.72 (n)
dog
(Canis familiaris)
Mammalia TMEM155 34
  • 85 (n)
cow
(Bos Taurus)
Mammalia LOC100337022 34
  • 84.11 (n)
Species where no ortholog for TMEM155 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM155 Gene

ENSEMBL:
Gene Tree for TMEM155 (if available)
TreeFam:
Gene Tree for TMEM155 (if available)

Paralogs for TMEM155 Gene

No data available for Paralogs for TMEM155 Gene

Variants for TMEM155 Gene

Sequence variations from dbSNP and Humsavar for TMEM155 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs10025131 -- 121,765,435(+) AGTCT(C/T)CCAGG nc-transcript-variant, upstream-variant-2KB
rs10470915 -- 121,762,910(+) ACAAC(C/T)ATAAT intron-variant, upstream-variant-2KB
rs10471016 -- 121,762,914(+) CTATA(A/C)TTGCT intron-variant, upstream-variant-2KB
rs10577662 -- 121,761,124(+) CAAAC(-/AA)AAAAA intron-variant
rs111670964 -- 121,760,510(+) GCCAC(C/G/T)TTAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM155 Gene

Variant ID Type Subtype PubMed ID
nsv508309 CNV deletion 20534489
nsv595357 CNV loss 21841781
nsv997539 CNV gain 25217958

Variation tolerance for TMEM155 Gene

Residual Variation Intolerance Score: 89.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.72; 32.66% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM155 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM155

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM155 Gene

Disorders for TMEM155 Gene

Relevant External Links for TMEM155

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM155

No disorders were found for TMEM155 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM155 Gene

Publications for TMEM155 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for TMEM155 Gene

Sources for TMEM155 Gene

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