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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM155 Gene

protein-coding   GIFtS: 35
GCID: GC04M122680

transmembrane protein 155
  Search for TMEM155
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TMEM155    

Aliases
for TMEM155 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Transmembrane Protein 1551 2
FLJ308341
Protein TMEM1552

External Ids:    HGNC: 264181   Entrez Gene: 1323322   Ensembl: ENSG000001641127   UniProtKB: Q4W5P63   

Export aliases for TMEM155 gene to outside databases

Previous GC identifers: GC04M122899 GC04M118407


Summaries
for TMEM155 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for TMEM155 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM155 gene promoter:
         TBP   Nkx3-1 v4   AML1a   Egr-1   AP-4   IRF-2   CP2   IRF-7A   MRF-2   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMEM155 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMEM155

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM155


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q27   Ensembl cytogenetic band:  4q27   HGNC cytogenetic band: 4q27

TMEM155 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM155 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M122680:  view genomic region     (about GC identifiers)

Start:
 122,680,085 bp from pter      End:
 122,686,582 bp from pter
Size:
 6,498 bases      Orientation:
 minus strand

Proteins
for TMEM155 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TM155_HUMAN, Q4W5P6 (See protein sequence)
Recommended Name: Protein TMEM155 precursor  
Size: 130 amino acids; 14221 Da
Subcellular location: Secreted (Potential)
Secondary accessions: D3DNW9 Q96NI2

Explore the universe of human proteins at neXtProt for TMEM155: NX_Q4W5P6

TMEM155 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_689612.2  
ENSEMBL proteins: 
 ENSP00000377919   ENSP00000336987   ENSP00000377917   ENSP00000422869  

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Uscn Proteins for TMEM155

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region IEA--


TMEM155 for ontologies           About GeneDecksing



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Uscn ELISAs and CLIAs for TMEM155

Protein Domains /
Families
for TMEM155 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q4W5P6


Function
for TMEM155 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
miRNA
Products:    		 OriGene 3'-UTR Clone: TMEM155
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM155
8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM155 (see all 12):
hsa-miR-34c-3p hsa-miR-3671 hsa-miR-1290 hsa-miR-767-3p hsa-miR-646 hsa-miR-4294 hsa-miR-182* hsa-miR-629*
SwitchGear 3'UTR luciferase reporter plasmid: TMEM155 3' UTR sequence
Inhib. RNA
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Gene Editing
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Clone
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Cell Line
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Search LifeMap BioReagents cell lines for TMEM155

In Situ Assay
Products:   
 		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM155


Pathways & Interactions
for TMEM155 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM155

Drugs & Compounds
for TMEM155 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMEM155
Search CenterWatch for drugs/clinical trials and news about TMEM155 / TM155 

Transcripts
for TMEM155 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for TMEM155 gene: 
NM_152399.2  

Unigene Cluster for TMEM155:

Transmembrane protein 155
Hs.27524  [show with all ESTs]
Unigene Representative Sequence: BC059365
8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000394396 ENST00000461198 ENST00000337677(uc003idx.1) ENST00000394394
ENST00000513254 ENST00000514885 ENST00000505198 ENST00000506551

miRNA
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8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM155 (see all 12):
hsa-miR-34c-3p hsa-miR-3671 hsa-miR-1290 hsa-miR-767-3p hsa-miR-646 hsa-miR-4294 hsa-miR-182* hsa-miR-629*
SwitchGear 3'UTR luciferase reporter plasmid: TMEM155 3' UTR sequence
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM155
OriGene shRNA RFP: TMEM155
OriGene siRNA: TMEM155
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Clone
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Primer
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Browse OriGene validated miRNA SYBR primer pairs
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM155
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM155

Additional cDNA sequence: 

AK055396.1 AK310583.1 BC047657.1 BC059365.1 

6 DOTS entries:

DT.210340  DT.121237542  DT.91962243  DT.100702327  DT.121237546  DT.91977739 

24/38 AceView cDNA sequences (see all 38):

BI757990 CR608317 AA699314 Z39835 AA693810 H10362 BQ011176 AW594645 
BX359598 AI184773 AL575833 AK055396 AA972788 NM_152399 BC059365 Z43772 
BC047657 BE552284 AW188040 N93749 BF673779 AI221736 BX327247 BX359599 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM155    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
SP1:              -                 -                     
SP2:                                                      


ECgene alternative splicing isoforms for TMEM155

Expression
for TMEM155 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMEM155 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGAAATGGC

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image

TMEM155 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
Stem Cell Differentiation: 2 LifeMap Cells 
NameCategory
PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
Line H9 (WA09) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See TMEM155 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM155

SOURCE GeneReport for Unigene cluster: Hs.27524
    SABiosciences Custom PCR Arrays for TMEM155
Primer
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM155
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM155
In Situ
Assay Products: 
 		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM155

Orthologs
for TMEM155 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
   --

ENSEMBL Gene Tree for TMEM155 (if available)
TreeFam Gene Tree for TMEM155 (if available) 

Paralogs
for TMEM155 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for TMEM155 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM155
DNA2.0 Custom Variant and Variant Library Synthesis for TMEM155

Disorders / Diseases
for TMEM155 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
   --

Publications
for TMEM155 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for TMEM155 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TMEM155)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

External Searches for TMEM155 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing TMEM155 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 132332 HGNC: 26418 AceView: FLJ30834 Ensembl:ENSG00000164112 euGenes: HUgn132332
ECgene: TMEM155 H-InvDB: TMEM155

Other Databases showing TMEM155 gene

(According to HUGE)
About This Section
   --

Specialized Databases showing TMEM155 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for TMEM155 Pharmacogenomics, SNPs, Pathways

Intellectual Property
for TMEM155 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for TMEM155 gene:
Search GeneIP for patents involving TMEM155

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for TMEM155 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section

 
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