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Aliases for TMEM151A Gene

Aliases for TMEM151A Gene

  • Transmembrane Protein 151A 2 3 5
  • Transmembrane Protein 151 2 3
  • TMEM151 3 4

External Ids for TMEM151A Gene

Previous HGNC Symbols for TMEM151A Gene

  • TMEM151

Previous GeneCards Identifiers for TMEM151A Gene

  • GC11P065819
  • GC11P066059
  • GC11P062384

Summaries for TMEM151A Gene

GeneCards Summary for TMEM151A Gene

TMEM151A (Transmembrane Protein 151A) is a Protein Coding gene. An important paralog of this gene is ENSG00000272442.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM151A Gene

Genomics for TMEM151A Gene

Regulatory Elements for TMEM151A Gene

Enhancers for TMEM151A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM151A on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM151A Gene

Chromosome:
11
Start:
66,291,870 bp from pter
End:
66,296,664 bp from pter
Size:
4,795 bases
Orientation:
Plus strand

Genomic View for TMEM151A Gene

Genes around TMEM151A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM151A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM151A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM151A Gene

Proteins for TMEM151A Gene

  • Protein details for TMEM151A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4L1-T151A_HUMAN
    Recommended name:
    Transmembrane protein 151A
    Protein Accession:
    Q8N4L1
    Secondary Accessions:
    • Q8ND14

    Protein attributes for TMEM151A Gene

    Size:
    468 amino acids
    Molecular mass:
    51278 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM151A Gene

Proteomics data for TMEM151A Gene at MOPED

Post-translational modifications for TMEM151A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM151A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM151A Gene

Domains & Families for TMEM151A Gene

Protein Domains for TMEM151A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM151A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N4L1

UniProtKB/Swiss-Prot:

T151A_HUMAN :
  • Belongs to the TMEM151 family.
Family:
  • Belongs to the TMEM151 family.
genes like me logo Genes that share domains with TMEM151A: view

No data available for Gene Families for TMEM151A Gene

Function for TMEM151A Gene

genes like me logo Genes that share phenotypes with TMEM151A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM151A Gene

Localization for TMEM151A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM151A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM151A Gene COMPARTMENTS Subcellular localization image for TMEM151A gene
Compartment Confidence
plasma membrane 3
peroxisome 2

No data available for Gene Ontology (GO) - Cellular Components for TMEM151A Gene

Pathways & Interactions for TMEM151A Gene

SuperPathways for TMEM151A Gene

No Data Available

Interacting Proteins for TMEM151A Gene

Gene Ontology (GO) - Biological Process for TMEM151A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM151A Gene

Drugs & Compounds for TMEM151A Gene

No Compound Related Data Available

Transcripts for TMEM151A Gene

mRNA/cDNA for TMEM151A Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(41) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM151A Gene

Transmembrane protein 151A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM151A Gene

No ASD Table

Relevant External Links for TMEM151A Gene

GeneLoc Exon Structure for
TMEM151A
ECgene alternative splicing isoforms for
TMEM151A

Expression for TMEM151A Gene

mRNA expression in normal human tissues for TMEM151A Gene

mRNA differential expression in normal tissues according to GTEx for TMEM151A Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x9.5), Brain - Substantia nigra (x5.9), Brain - Hippocampus (x4.9), and Brain - Cortex (x4.2).

Protein differential expression in normal tissues from HIPED for TMEM151A Gene

This gene is overexpressed in Spinal cord (39.2) and Colon (22.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM151A Gene



SOURCE GeneReport for Unigene cluster for TMEM151A Gene Hs.399779

genes like me logo Genes that share expression patterns with TMEM151A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMEM151A Gene

Orthologs for TMEM151A Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM151A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM151A 35
  • 93.02 (n)
  • 98.29 (a)
TMEM151A 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC483713 35
  • 91.45 (n)
  • 97.65 (a)
TMEM151A 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem151a 35
  • 86.89 (n)
  • 97.44 (a)
Tmem151a 16
Tmem151a 36
  • 97 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TMEM151A 35
  • 99.64 (n)
  • 100 (a)
TMEM151A 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100911978 35
  • 86.47 (n)
  • 97.44 (a)
oppossum
(Monodelphis domestica)
Mammalia TMEM151A 36
  • 89 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii Dr.14563 35
LOC793560 35
  • 63.8 (n)
  • 64.2 (a)
tmem151a 36
  • 42 (a)
OneToMany
TMEM151A (1 of 2) 36
  • 43 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ZK1067.4 35
  • 42.99 (n)
  • 40.24 (a)
ZK1067.4 36
  • 28 (a)
OneToMany
Species with no ortholog for TMEM151A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TMEM151A Gene

ENSEMBL:
Gene Tree for TMEM151A (if available)
TreeFam:
Gene Tree for TMEM151A (if available)

Paralogs for TMEM151A Gene

Paralogs for TMEM151A Gene

(1) SIMAP similar genes for TMEM151A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMEM151A: view

Variants for TMEM151A Gene

Sequence variations from dbSNP and Humsavar for TMEM151A Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs560577 -- 66,296,655(+) AGGTA(C/T)GGAAT utr-variant-3-prime
rs1938916 -- 66,292,830(-) AGGGA(A/C)TCACT intron-variant
rs11602619 -- 66,295,473(+) CTGGG(C/G)GCTGG reference, synonymous-codon
rs112089750 -- 66,291,677(+) ACCAG(C/T)TCAAG upstream-variant-2KB
rs112148750 -- 66,295,266(+) GCCAC(A/G)GTGGA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for TMEM151A Gene

Variant ID Type Subtype PubMed ID
dgv1187n71 CNV Loss 21882294
nsv897772 CNV Loss 21882294
dgv1188n71 CNV Loss 21882294
nsv897779 CNV Loss 21882294
esv32849 CNV Gain 17666407

Variation tolerance for TMEM151A Gene

Gene Damage Index Score: 1.18; 23.73% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TMEM151A Gene

Disorders for TMEM151A Gene

Relevant External Links for TMEM151A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM151A

No disorders were found for TMEM151A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM151A Gene

Publications for TMEM151A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) (Nat. Genet. 2011) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for TMEM151A Gene

Sources for TMEM151A Gene

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