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Aliases for TMEM150C Gene

Aliases for TMEM150C Gene

  • Transmembrane Protein 150C 2 3

External Ids for TMEM150C Gene

Previous GeneCards Identifiers for TMEM150C Gene

  • GC04M083625
  • GC04M083405
  • GC04M079146

Summaries for TMEM150C Gene

GeneCards Summary for TMEM150C Gene

TMEM150C (Transmembrane Protein 150C) is a Protein Coding gene. An important paralog of this gene is TMEM150B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM150C Gene

Genomics for TMEM150C Gene

Genomic Location for TMEM150C Gene

Start:
82,483,170 bp from pter
End:
82,562,357 bp from pter
Size:
79,188 bases
Orientation:
Minus strand

Genomic View for TMEM150C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM150C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM150C Gene

No data available for Regulatory Elements for TMEM150C Gene

Proteins for TMEM150C Gene

  • Protein details for TMEM150C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B9EJG8-T150C_HUMAN
    Recommended name:
    Transmembrane protein 150C
    Protein Accession:
    B9EJG8
    Secondary Accessions:
    • B7Z4J5
    • B7Z4L3
    • B7Z692
    • B7Z6X6

    Protein attributes for TMEM150C Gene

    Size:
    249 amino acids
    Molecular mass:
    27887 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAH12581.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM150C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM150C Gene

Proteomics data for TMEM150C Gene at MOPED

Post-translational modifications for TMEM150C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM150C Gene

No data available for DME Specific Peptides for TMEM150C Gene

Domains for TMEM150C Gene

Protein Domains for TMEM150C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM150C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B9EJG8

UniProtKB/Swiss-Prot:

T150C_HUMAN :
  • B9EJG8
Family:
  • Belongs to the DRAM/TMEM150 family.
genes like me logo Genes that share domains with TMEM150C: view

No data available for Gene Families for TMEM150C Gene

Function for TMEM150C Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM150C Gene

Localization for TMEM150C Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM150C Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM150C Gene COMPARTMENTS Subcellular localization image for TMEM150C gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM150C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005764 lysosome IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM150C: view

Pathways for TMEM150C Gene

SuperPathways for TMEM150C Gene

No Data Available

Interacting Proteins for TMEM150C Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000403438%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000403438 for TMEM150C Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for TMEM150C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030262 apoptotic nuclear changes IBA --
genes like me logo Genes that share ontologies with TMEM150C: view

No data available for Pathways by source for TMEM150C Gene

Transcripts for TMEM150C Gene

mRNA/cDNA for TMEM150C Gene

Unigene Clusters for TMEM150C Gene

Transmembrane protein 150C:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM150C

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TMEM150C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM150C Gene

No ASD Table

Relevant External Links for TMEM150C Gene

GeneLoc Exon Structure for
TMEM150C
ECgene alternative splicing isoforms for
TMEM150C

Expression for TMEM150C Gene

mRNA expression in normal human tissues for TMEM150C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM150C Gene

This gene is overexpressed in Adrenal Gland (5.2).

SOURCE GeneReport for Unigene cluster for TMEM150C Gene Hs.507676

genes like me logo Genes that share expressions with TMEM150C: view

In Situ Assay Products

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for TMEM150C Gene

Orthologs for TMEM150C Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM150C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM150C 35
  • 100 (n)
  • 100 (a)
TMEM150C 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM150C 35
  • 93.31 (n)
  • 97.59 (a)
TMEM150C 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM150C 35
  • 93.98 (n)
  • 98.39 (a)
TMEM150C 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem150c 35
  • 87.28 (n)
  • 95.98 (a)
Tmem150c 16
Tmem150c 36
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM150C 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM150C 36
  • 87 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem150c 35
  • 88.09 (n)
  • 96.79 (a)
chicken
(Gallus gallus)
Aves TMEM150C 35
  • 80.19 (n)
  • 90.76 (a)
TMEM150C 36
  • 91 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM150C 36
  • 85 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem150c 35
  • 73.92 (n)
  • 76.61 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem150c 35
  • 68.43 (n)
  • 66.67 (a)
tmem150c 36
  • 67 (a)
OneToOne
Species with no ortholog for TMEM150C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM150C Gene

ENSEMBL:
Gene Tree for TMEM150C (if available)
TreeFam:
Gene Tree for TMEM150C (if available)

Paralogs for TMEM150C Gene

Paralogs for TMEM150C Gene

Selected SIMAP similar genes for TMEM150C Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TMEM150C: view

Variants for TMEM150C Gene

Sequence variations from dbSNP and Humsavar for TMEM150C Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs869169 -- 82,498,759(+) CAGGG(C/G/T)AACAG intron-variant
rs873931 -- 82,500,743(-) TGTAT(A/G)CTTTT intron-variant
rs953186 -- 82,512,253(-) GTCTC(A/G)TGGTT intron-variant
rs1316596 -- 82,529,918(-) AACCA(C/T)AAAAT intron-variant
rs1543163 -- 82,490,482(+) AACAG(A/C)AGGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM150C Gene

Variant ID Type Subtype PubMed ID
nsv829988 CNV Loss 17160897
nsv829989 CNV Loss 17160897
esv28726 CNV Loss 19812545

Relevant External Links for TMEM150C Gene

HapMap Linkage Disequilibrium report
TMEM150C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM150C Gene

Disorders for TMEM150C Gene

No disorders were found for TMEM150C Gene.

No data available for UniProtKB/Swiss-Prot for TMEM150C Gene

Publications for TMEM150C Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMEM150C Gene

Sources for TMEM150C Gene

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