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Aliases for TMEM150A Gene

Aliases for TMEM150A Gene

  • Transmembrane Protein 150A 2 3
  • Transmembrane Protein 150 2 3 4
  • TMEM150 3 4
  • Fasting-Inducible Integral Membrane Protein TM6P1 3
  • TM6P1 3

External Ids for TMEM150A Gene

Previous Symbols for TMEM150A Gene

  • TMEM150

Summaries for TMEM150A Gene

GeneCards Summary for TMEM150A Gene

TMEM150A (Transmembrane Protein 150A) is a Protein Coding gene. An important paralog of this gene is TMEM150B.

UniProtKB/Swiss-Prot for TMEM150A Gene

  • Possible role in fasting-induced catabolism.

Gene Wiki entry for TMEM150A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM150A Gene

Genomics for TMEM150A Gene

Genomic Location for TMEM150A Gene

Start:
85,598,547 bp from pter
End:
85,603,196 bp from pter
Size:
4,650 bases
Orientation:
Minus strand

Genomic View for TMEM150A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM150A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM150A Gene

No data available for Regulatory Elements for TMEM150A Gene

Proteins for TMEM150A Gene

  • Protein details for TMEM150A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86TG1-T150A_HUMAN
    Recommended name:
    Transmembrane protein 150A
    Protein Accession:
    Q86TG1
    Secondary Accessions:
    • A8K764
    • B7WPQ9
    • D6W5L2
    • Q8N2R6

    Protein attributes for TMEM150A Gene

    Size:
    271 amino acids
    Molecular mass:
    28835 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM150A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM150A Gene

Proteomics data for TMEM150A Gene at MOPED

Post-translational modifications for TMEM150A Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn37 and Asn41

Other Protein References for TMEM150A Gene

No data available for DME Specific Peptides for TMEM150A Gene

Domains for TMEM150A Gene

Protein Domains for TMEM150A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

T150A_HUMAN
Family:
  • Belongs to the DRAM/TMEM150 family.:
    • Q86TG1
genes like me logo Genes that share domains with TMEM150A: view

No data available for Gene Families for TMEM150A Gene

Function for TMEM150A Gene

Molecular function for TMEM150A Gene

UniProtKB/Swiss-Prot Function: Possible role in fasting-induced catabolism.

Gene Ontology (GO) - Molecular Function for TMEM150A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM150A: view

Phenotypes for TMEM150A Gene

GenomeRNAi human phenotypes for TMEM150A:
genes like me logo Genes that share phenotypes with TMEM150A: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM150A Gene

Localization for TMEM150A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM150A Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM150A Gene COMPARTMENTS Subcellular localization image for TMEM150A gene
Compartment Confidence
plasma membrane 5
nucleus 1

Gene Ontology (GO) - Cellular Components for TMEM150A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005764 lysosome IBA --
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM150A: view

Pathways for TMEM150A Gene

SuperPathways for TMEM150A Gene

No Data Available

Interacting Proteins for TMEM150A Gene

Gene Ontology (GO) - Biological Process for TMEM150A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009056 catabolic process IEA --
GO:0030262 apoptotic nuclear changes IBA --
genes like me logo Genes that share ontologies with TMEM150A: view

No data available for Pathways by source for TMEM150A Gene

Transcripts for TMEM150A Gene

Unigene Clusters for TMEM150A Gene

Transmembrane protein 150A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM150A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b · 11c · 11d · 11e
SP1: - - - - - - - - -
SP2: - - - - - - - - - -
SP3: - - - - - - -
SP4: - - - - - -
SP5: - - - -
SP6: - - - - - -
SP7: - - - -
SP8: - - - - - -
SP9: - - - - - -
SP10: - - - -
SP11: - - - - - - -
SP12: - - - -
SP13: - - - - -
SP14: - -

Relevant External Links for TMEM150A Gene

GeneLoc Exon Structure for
TMEM150A
ECgene alternative splicing isoforms for
TMEM150A

Expression for TMEM150A Gene

mRNA expression in normal human tissues for TMEM150A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TMEM150A Gene

SOURCE GeneReport for Unigene cluster for TMEM150A Gene Hs.591559

genes like me logo Genes that share expressions with TMEM150A: view

Orthologs for TMEM150A Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM150A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM150A 36
  • 99.63 (n)
  • 100 (a)
TMEM150A 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM150A 36
  • 88.31 (n)
  • 92.62 (a)
TMEM150A 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM150A 36
  • 89.91 (n)
  • 90.77 (a)
TMEM150A 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem150a 36
  • 89.05 (n)
  • 91.51 (a)
Tmem150a 16
Tmem150a 37
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM150A 37
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM150A 37
  • 84 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem150a 36
  • 89.54 (n)
  • 92.25 (a)
chicken
(Gallus gallus)
Aves TMEM150A 37
  • 55 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM150A 37
  • 78 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.15465 36
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem150a 36
  • 70.23 (n)
  • 70.11 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem150a 37
  • 64 (a)
OneToMany
TMEM150A (1 of 4) 37
  • 64 (a)
OneToMany
TMEM150A (2 of 4) 37
  • 30 (a)
OneToMany
TMEM150A (4 of 4) 37
  • 53 (a)
OneToMany
zgc66242 36
zgc:66242 36
  • 68.27 (n)
  • 69.74 (a)
Species with no ortholog for TMEM150A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM150A Gene

ENSEMBL:
Gene Tree for TMEM150A (if available)
TreeFam:
Gene Tree for TMEM150A (if available)

Paralogs for TMEM150A Gene

Paralogs for TMEM150A Gene

genes like me logo Genes that share paralogs with TMEM150A: view

Variants for TMEM150A Gene

Sequence variations from dbSNP and Humsavar for TMEM150A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs10302 -- 85,598,452(+) CACTC(A/G)GCACT downstream-variant-500B
rs1044157 -- 85,599,111(-) CCCAC(C/T)TCAAC reference, missense, nc-transcript-variant
rs1044158 -- 85,599,009(-) TATTT(C/T)GTACC utr-variant-3-prime, nc-transcript-variant
rs3198089 -- 85,598,214(+) CTTTT(C/T)GCTCC downstream-variant-500B
rs6718028 -- 85,600,638(+) TCGGG(A/C)AACCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM150A Gene

Variant ID Type Subtype PubMed ID
dgv4202n71 CNV Loss 21882294

Relevant External Links for TMEM150A Gene

HapMap Linkage Disequilibrium report
TMEM150A

Disorders for TMEM150A Gene

No disorders were found for TMEM150A Gene.

No data available for UniProtKB/Swiss-Prot for TMEM150A Gene

Publications for TMEM150A Gene

  1. Identification of a new gene (rat TM6P1) encoding a fasting-inducible, integral membrane protein with six transmembrane domains. (PMID: 10858565) Zhang J. … Underwood L.E. (Biochim. Biophys. Acta 2000) 2 3
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3

Products for TMEM150A Gene

Sources for TMEM150A Gene

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