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Aliases for TMEM14EP Gene

Aliases for TMEM14EP Gene

  • Transmembrane Protein 14E, Pseudogene 2 3 5
  • TMEM14E 3 4
  • Transmembrane Protein 14E 2

External Ids for TMEM14EP Gene

Previous HGNC Symbols for TMEM14EP Gene

  • TMEM14E

Summaries for TMEM14EP Gene

GeneCards Summary for TMEM14EP Gene

TMEM14EP (Transmembrane Protein 14E, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM14EP Gene

Genomics for TMEM14EP Gene

Regulatory Elements for TMEM14EP Gene

Enhancers for TMEM14EP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G152381 1.8 FANTOM5 Ensembl ENCODE dbSUPER 17 -43.5 -43462 5.5 PKNOX1 ATF1 FOXA2 YY1 TBX21 KAT8 ZNF592 RCOR2 NBN ASH2L TMEM14EP MBNL1 GC03P152450
GH03G152374 1.5 Ensembl ENCODE dbSUPER 20.2 -35.3 -35311 4.2 HDGF PKNOX1 SIN3A CBX5 ZNF207 JUNB NCOA1 TBX21 SMARCB1 MEF2D TMEM14EP MBNL1 GC03P152450
GH03G152314 1.5 Ensembl ENCODE dbSUPER 19.8 +21.3 21326 9.9 PKNOX1 FOXA2 ATF1 ARNT ZBTB7B YY1 TCF12 CBX5 GATA2 ZNF143 TMEM14EP MBNL1-AS1 MBNL1 LOC105374162 GC03M152329
GH03G152297 1.3 ENCODE dbSUPER 19.3 +41.7 41653 2.9 PKNOX1 ATF1 FOXA2 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 TMEM14EP MBNL1-AS1 MBNL1 LOC105374162
GH03G152305 1.4 Ensembl ENCODE dbSUPER 17.7 +32.5 32546 5.0 HNRNPUL1 RAD21 RARA ZNF121 GATA4 POLR3A FOS RCOR1 MBD2 SREBF1 TMEM14EP MBNL1-AS1 MBNL1 LOC105374162
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TMEM14EP on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM14EP Gene

Chromosome:
3
Start:
152,339,695 bp from pter
End:
152,340,990 bp from pter
Size:
1,296 bases
Orientation:
Minus strand

Genomic View for TMEM14EP Gene

Genes around TMEM14EP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM14EP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM14EP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM14EP Gene

Proteins for TMEM14EP Gene

  • Protein details for TMEM14EP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UXP3-TM14E_HUMAN
    Recommended name:
    Transmembrane protein 14EP
    Protein Accession:
    Q6UXP3

    Protein attributes for TMEM14EP Gene

    Size:
    125 amino acids
    Molecular mass:
    13608 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM14EP Gene

Post-translational modifications for TMEM14EP Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMEM14EP Gene

Domains & Families for TMEM14EP Gene

Protein Domains for TMEM14EP Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM14EP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6UXP3

UniProtKB/Swiss-Prot:

TM14E_HUMAN :
  • Belongs to the TMEM14 family.
Family:
  • Belongs to the TMEM14 family.
genes like me logo Genes that share domains with TMEM14EP: view

No data available for Gene Families for TMEM14EP Gene

Function for TMEM14EP Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM14EP Gene

Localization for TMEM14EP Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM14EP Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM14EP gene
Compartment Confidence
extracellular 3
mitochondrion 1
nucleus 1
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for TMEM14EP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM14EP: view

Pathways & Interactions for TMEM14EP Gene

SuperPathways for TMEM14EP Gene

No Data Available

Interacting Proteins for TMEM14EP Gene

Gene Ontology (GO) - Biological Process for TMEM14EP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM14EP Gene

Drugs & Compounds for TMEM14EP Gene

No Compound Related Data Available

Transcripts for TMEM14EP Gene

mRNA/cDNA for TMEM14EP Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM14EP Gene

No ASD Table

Relevant External Links for TMEM14EP Gene

GeneLoc Exon Structure for
TMEM14EP
ECgene alternative splicing isoforms for
TMEM14EP

Expression for TMEM14EP Gene

NURSA nuclear receptor signaling pathways regulating expression of TMEM14EP Gene:

TMEM14EP
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM14EP Gene

Orthologs for TMEM14EP Gene

Evolution for TMEM14EP Gene

ENSEMBL:
Gene Tree for TMEM14EP (if available)
TreeFam:
Gene Tree for TMEM14EP (if available)

No data available for Orthologs for TMEM14EP Gene

Paralogs for TMEM14EP Gene

No data available for Paralogs for TMEM14EP Gene

Variants for TMEM14EP Gene

Sequence variations from dbSNP and Humsavar for TMEM14EP Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1001976098 -- 152,342,807(+) TAACT(A/C)CACAT intron-variant, upstream-variant-2KB
rs1002840389 -- 152,341,574(+) CCATT(G/T)TTTCC intron-variant, upstream-variant-2KB
rs1003882800 -- 152,341,226(+) GTGGC(A/T)CAGTC intron-variant, upstream-variant-2KB
rs1006229427 -- 152,341,148(+) TTCAT(A/G)TATAA intron-variant, upstream-variant-2KB
rs1006630196 -- 152,340,916(+) CTTCT(A/G)ATTCT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM14EP Gene

Variant ID Type Subtype PubMed ID
nsv483030 CNV gain 15286789
nsv954493 CNV duplication 24416366

Variation tolerance for TMEM14EP Gene

Residual Variation Intolerance Score: 80.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.27; 40.72% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM14EP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM14EP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM14EP Gene

Disorders for TMEM14EP Gene

Relevant External Links for TMEM14EP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM14EP
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM14EP

No disorders were found for TMEM14EP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM14EP Gene

Publications for TMEM14EP Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4 64
  2. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 64

Products for TMEM14EP Gene

Sources for TMEM14EP Gene

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