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TMEM14B Gene

protein-coding   GIFtS: 43
GCID: GC06P010747

Transmembrane Protein 14B

  Search for TMEM14B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 14B1 2

External Ids:    HGNC: 213841   Entrez Gene: 818532   Ensembl: ENSG000001372107   UniProtKB: Q9NUH83   

Export aliases for TMEM14B gene to outside databases

Previous GC identifers: GC06P010810 GC06P010856 GC06P010624


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM14B Gene:
TMEM14B (transmembrane protein 14B) is a protein-coding gene. An important paralog of this gene is TMEM14A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM14B gene promoter:
         Bach1   Pax-6   Lmo2   POU2F1   POU2F1b   POU2F1a   Sox9   POU2F1c   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM14B promoter sequence
   Search Chromatin IP Primers for TMEM14B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM14B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p25.1-p23   Ensembl cytogenetic band:  6p24.2   HGNC cytogenetic band: 6p25.1-p23

TMEM14B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM14B gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P010747:  view genomic region     (about GC identifiers)

Start:
10,747,992 bp from pter      End:
10,852,986 bp from pter
Size:
104,995 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TM14B_HUMAN, Q9NUH8 (See protein sequence)
Recommended Name: Transmembrane protein 14B  
Size: 114 amino acids; 12078 Da
Secondary accessions: Q5THN7 Q5THN8 Q96IX7 Q9BVN8
Alternative splicing: 2 isoforms:  Q9NUH8-1   Q9NUH8-2   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for TMEM14B: NX_Q9NUH8

Explore proteomics data for TMEM14B at MOPED


See TMEM14B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (5 alternative transcripts): 
NP_001121183.1  NP_001273413.1  NP_001273417.1  NP_001273418.1  NP_112231.3  

ENSEMBL proteins: 
 ENSP00000368858   ENSP00000417416   ENSP00000419208   ENSP00000417095   ENSP00000419156  
 ENSP00000418334   ENSP00000418730   ENSP00000368845   ENSP00000419806   ENSP00000420580  
 ENSP00000420172   ENSP00000420658   ENSP00000418927   ENSP00000419731  

TMEM14B Human Recombinant Protein Products:

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Novus Biologicals TMEM14B Lysate
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Cloud-Clone Corp. Proteins for TMEM14B

 
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ThermoFisher Antibodies for TMEM14B
LSBio Antibodies in human, mouse, rat for TMEM14B

TMEM14B Assay Products:

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Cloud-Clone Corp. ELISAs for TMEM14B
Cloud-Clone Corp. CLIAs for TMEM14B
Search eBioscience for ELISAs for TMEM14B 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR005349 UPF0136_TM

Graphical View of Domain Structure for InterPro Entry Q9NUH8

ProtoNet protein and cluster: Q9NUH8

1 Blocks protein domain: IPB005349 Protein of unknown function UPF0136

UniProtKB/Swiss-Prot: TM14B_HUMAN, Q9NUH8
Similarity: Belongs to the UPF0136 (TMEM14) family


Find genes that share domains with TMEM14B           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Phenotypes:
     4 GenomeRNAi human phenotypes for TMEM14B:
 Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Increased gamma-H2AX phosphory 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM14B
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM14B
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM14B

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat TMEM14B using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate TMEM14B:
hsa-miR-3145-3p
SwitchGear 3'UTR luciferase reporter plasmidTMEM14B 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for TMEM14B
Predesigned siRNA for gene silencing in human, mouse, rat TMEM14B

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for TMEM14B

Clone
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OriGene clones in human, mouse for TMEM14B (see all 11)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): TMEM14B (NM_030969)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM14B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM14B

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM14B


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
TM14B_HUMAN, Q9NUH8: Membrane; Multi-pass membrane protein (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular2
endoplasmic reticulum1
mitochondrion1
nucleus1
peroxisome1
plasma membrane1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016020membrane ----
GO:0016021integral component of membrane IEA--

Find genes that share ontologies with TMEM14B           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM14B
Interactions:

    Search GeneGlobe Interaction Network for TMEM14B

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

Selected Interacting proteins for TMEM14B (Q9NUH83 ENSP000003688584) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
InteractantInteraction Details
GeneCardExternal ID(s)
AGTRAPQ6RW133I2D: score=1 
CREB3O438893I2D: score=1 
KHDRBS2Q5VWX13I2D: score=1 
MID2Q9UJV33I2D: score=1 
PPP2R3BQ9Y5P83I2D: score=1 
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for TMEM14B (TM14B)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for TMEM14B gene (5 alternative transcripts): 
NM_001127711.2  NM_001286484.1  NM_001286488.1  NM_001286489.1  NM_030969.4  

Unigene Cluster for TMEM14B:

Transmembrane protein 14B
Hs.95600  [show with all ESTs]
Unigene Representative Sequence: AK311340
Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
ENST00000379542(uc003mzk.4 uc010jor.3) ENST00000473166 ENST00000463448(uc010jos.1)
ENST00000460341 ENST00000480194 ENST00000491103 ENST00000473807 ENST00000492297
ENST00000461342 ENST00000475942 ENST00000379530 ENST00000463100 ENST00000473276
ENST00000481240 ENST00000467317 ENST00000478732 ENST00000486421 ENST00000467229

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat TMEM14B using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate TMEM14B:
hsa-miR-3145-3p
SwitchGear 3'UTR luciferase reporter plasmidTMEM14B 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for TMEM14B
Predesigned siRNA for gene silencing in human, mouse, rat TMEM14B
Clone
Products:
     
OriGene clones in human, mouse for TMEM14B (see all 11)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): TMEM14B (NM_030969)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM14B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM14B
Primer
Products:
    
OriGene qPCR primer pairs and template standards for TMEM14B
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM14B
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat TMEM14B
  QuantiTect SYBR Green Assays in human, mouse, rat TMEM14B
  QuantiFast Probe-based Assays in human, mouse, rat TMEM14B

Additional mRNA sequence: 

AK291883.1 AK294152.1 AK311340.1 BC001033.1 BC007080.1 BC013913.1 BC071660.1 

21 DOTS entries:

DT.87017216  DT.99960630  DT.121397398  DT.121397466  DT.95262805  DT.121397496  DT.100033338  DT.100796494 
DT.102834849  DT.121397367  DT.121397404  DT.121397454  DT.121397539  DT.75104796  DT.95356477  DT.121397502 
DT.40245627  DT.75164572  DT.87017218  DT.91838838  DT.92452626 

Selected AceView cDNA sequences (see all 663):

AW439156 AW162019 BF440052 BQ272210 CB130241 BM887873 BU947678 BU948332 
BQ935722 CR594179 AA120782 AI873685 CD367082 AI419601 BC002496 BU782977 
AI142474 BE732828 CB136963 AA831991 CR618403 BM661517 BC010086 BQ007519 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM14B (see all 8)    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b
SP1:                                -                                             
SP2:                                -                 -     -     -               
SP3:                                -     -                                       
SP4:                          -     -                                             
SP5:                                -     -           -     -     -               


ECgene alternative splicing isoforms for TMEM14B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TMEM14B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGCTTATTGA
TMEM14B Expression
About this image

TMEM14B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

TMEM14B Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.95600
    Custom PCR Arrays for TMEM14B
Primer
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QuantiTect SYBR Green Assays in human, mouse, rat TMEM14B
QuantiFast Probe-based Assays in human, mouse, rat TMEM14B
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM14B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for TMEM14B gene from Selected species (see all 9)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
62(a)
1 → many
GL343209.1(2583459-2588653)
zebrafish
(Danio rerio)
Actinopterygii tmem14ca6
tmem14cb6
transmembrane protein 14Cb
58(a)
46(a)
many ↔ many
many ↔ many
24(8536095-8541428) ENSDARG00000075180
24(37626127-37633312) ENSDARG00000079272
fruit fly
(Drosophila melanogaster)
Insecta CG55326
--
39(a)
1 → many
2R(19640264-19640929)
        Species with no ortholog for TMEM14B

ENSEMBL Gene Tree for TMEM14B (if available)
TreeFam Gene Tree for TMEM14B (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for TMEM14B gene
TMEM14A2  TMEM14C2  
Selected SIMAP similar genes for TMEM14B using alignment to 9 protein entries:     TM14B_HUMAN (see all proteins) (see all similar genes):
NRAMP1    HECW1    MEFV    FAM3A    RUFY1    ZNF737
EDRF1    TMEM14D    CERS5    NEK4    RBMS2    ZNF28
ZNF738    AEBP2    AURA2    DCTN5    ZNF212    AGBL3

Find genes that share paralogs with TMEM14B           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for TMEM14B (see all 223)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs603891481,2
C,F--10745998(+) CCAATG/AAATAT 2 -- us2k14Minor allele frequency- A:0.24WA CSA 123
rs588186261,2
C,F--10746008(+) TGATCC/TAGAAG 2 -- us2k14Minor allele frequency- T:0.24WA CSA 123
rs592198501,2
C--10746047(+) ATAGGT/CGGTTT 2 -- us2k12Minor allele frequency- C:0.33WA CSA 3
rs1409443071,2
C--10746049(+) GGCGG-/GTTTTT
TTTTTTTTT
TTTTT
2 -- cds10--------
rs602815571,2
--10746050(+) GGCGGG/TTTTTT 2 -- us2k10--------
rs1137429381,2
C--10746050(+) GGCGG-/TTTTTTT 2 -- us2k11Minor allele frequency- TT:0.00CSA 2
rs1930563311,2
--10746118(+) ACCTAC/TAAAAT 2 -- us2k10--------
rs1382063331,2
F--10749913(+) GGATCG/ATTGGC 4 /I /V mis11Minor allele frequency- A:0.00NA 4550
rs2020703101,2
C--10749953(+) ACTTAA/GCCTCT 2 -- int10--------
rs1869104701,2
--10750007(+) CCTGAC/GAAGCA 2 -- int10--------

HapMap Linkage Disequilibrium report for TMEM14B (10747992 - 10852986 bp)

Structural Variations
     Database of Genomic Variants (DGV) 5 variations for TMEM14B:    About this table    
Variant IDTypeSubtypePubMed ID
esv2731586CNV Deletion23290073
esv2663502CNV Deletion23128226
esv2677566CNV Deletion23128226
nsv462631CNV Gain19166990
nsv470800CNV Gain18288195

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing TMEM14B
DNA2.0 Custom Variant and Variant Library Synthesis for TMEM14B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for TMEM14B gene integrated from 10 sources:
(articles sorted by number of sources associating them with TMEM14B)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  6. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
  7. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (Nature 2003)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 81853 HGNC: 21384 AceView: TMEM14CandTMEM14B Ensembl:ENSG00000137210 euGenes: HUgn81853
ECgene: TMEM14B H-InvDB: TMEM14B

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TMEM14B Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TMEM14B gene:
Search GeneIP for patents involving TMEM14B

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM14B  
 OriGene qPCR primer pairs and template standards for TMEM14B   OriGene Protein Over-expression Lysate for TMEM14B  
 OriGene MassSpec something-or-other for TMEM14B   OriGene clones in human, mouse for TMEM14B  
 OriGene qSTAR qPCR primer pairs in human, mouse for TMEM14B   OriGene Purified Protein for TMEM14B  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for TMEM14B   OriGene Custom Protein Services for TMEM14B  

 
 
 Block miRNA regulation of human, mouse, rat TMEM14B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM14B
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM14B Predesigned siRNA for gene silencing in human, mouse, rat TMEM14B
 QuantiFast Probe-based Assays in human, mouse, rat TMEM14B QuantiTect SYBR Green Assays in human, mouse, rat TMEM14B
 Custom PCR Arrays for TMEM14B Search Chromatin IP Primers for TMEM14B
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat TMEM14B  Search GeneGlobe Interaction Network for TMEM14B
 Regulatory tfbs in TMEM14B promoter
 GenScript Custom Purified and Recombinant Proteins Services for TMEM14B GenScript cDNA clones with any tag delivered in your preferred vector for TMEM14B
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 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
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 Search Tocris compounds for TMEM14B (TM14B)
 Browse Sino Biological Proteins
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 Protein Production Services
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 TMEM14B lysates
 Search for Antibodies for TMEM14B at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for TMEM14B
 Custom Antibody / Protein Production Service
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for TMEM14B
 Antibodies for TMEM14B
 ELISAs for TMEM14B
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 Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM14B
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM14B
 SwitchGear 3'UTR luciferase reporter plasmids for TMEM14B
 SwitchGear Promoter luciferase reporter plasmids for TMEM14B
 ThermoFisher Antibodies for TMEM14B
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM14B
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM14B
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM14B
 LSBio Antibodies in human, mouse, rat for TMEM14B
Customized transgenic rodents for:
 Humanization
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 Tissue-specific gene expresssion
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 Browse compounds at ApexBio
 Search Addgene for plasmids for TMEM14B
  Search eBioscience for proteins for TMEM14B
  Search eBioscience for elisas for TMEM14B
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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