Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM14A Gene

protein-coding   GIFtS: 46
GCID: GC06P052535

Transmembrane Protein 14A

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane Protein 14A1 2
C6orf732 3

External Ids:    HGNC: 210761   Entrez Gene: 289782   Ensembl: ENSG000000960927   UniProtKB: Q9Y6G13   

Export aliases for TMEM14A gene to outside databases

Previous GC identifers: GC06P052538 GC06P052582 GC06P052643 GC06P052367


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TMEM14A Gene: 
TMEM14A (transmembrane protein 14A) is a protein-coding gene. Diseases associated with TMEM14A include juvenile myoclonic epilepsy, and idiopathic generalized epilepsy. An important paralog of this gene is TMEM14B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM14A gene promoter:
         Oct-B1   POU2F2 (Oct-2.1)   oct-B2   oct-B3   POU2F2   POU2F2C   SRY   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM14A promoter sequence
   Search SABiosciences Chromatin IP Primers for TMEM14A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM14A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.2   Ensembl cytogenetic band:  6p12.2   HGNC cytogenetic band: 6p12.3

TMEM14A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM14A gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P052535:  view genomic region     (about GC identifiers)

Start:
52,535,884 bp from pter      End:
52,551,386 bp from pter
Size:
15,503 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TM14A_HUMAN, Q9Y6G1 (See protein sequence)
Recommended Name: Transmembrane protein 14A  
Size: 99 amino acids; 10712 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
2 PDB 3D structures from and Proteopedia for TMEM14A:
2LOO (3D)        2LOP (3D)    
Secondary accessions: B2R552

Explore the universe of human proteins at neXtProt for TMEM14A: NX_Q9Y6G1

Explore proteomics data for TMEM14A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y6G1

  • TMEM14A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMEM14A Protein Expression
    REFSEQ proteins: NP_054770.1  
    ENSEMBL proteins: 
     ENSP00000211314  

    Human Recombinant Protein Products for TMEM14A: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TMEM14A
    GenScript Custom Purified and Recombinant Proteins Services for TMEM14A
    Novus Biologicals TMEM14A Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM14A 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    TMEM14A for ontologies           About GeneDecksing



    TMEM14A Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM14A
    GenScript Custom Superior Antibodies Services for TMEM14A
    Novus Biologicals TMEM14A Antibody
    Search for Antibodies for TMEM14A at Abcam
    Cloud-Clone Corp. Antibodies for TMEM14A 
    Search ThermoFisher Antibodies for TMEM14A
    Search LSBio for Antibodies for TMEM14A 

    Assay Products for TMEM14A: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM14A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM14A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM14A 
    Cloud-Clone Corp. CLIAs for TMEM14A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR005349 UPF0136_TM

    Graphical View of Domain Structure for InterPro Entry Q9Y6G1

    ProtoNet protein and cluster: Q9Y6G1

    1 Blocks protein domain: IPB005349 Protein of unknown function UPF0136

    UniProtKB/Swiss-Prot: TM14A_HUMAN, Q9Y6G1
    Similarity: Belongs to the UPF0136 (TMEM14) family


    TMEM14A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMEM14A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMEM14A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM14A 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM14A 

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM14A:
    hsa-mir-373 (MIRT002540)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM14A
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM14A:
    hsa-miR-200c hsa-miR-429 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidTMEM14A 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMEM14A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM14A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM14A
    Sirion Biotech Customized adenovirus for overexpression of TMEM14A

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TMEM14A (see all 7)
    OriGene ORF clones in mouse, rat for TMEM14A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM14A (NM_014051)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM14A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM14A
    Sirion Biotech Customized lentivirus for stable overexpression of TMEM14A 
                         Customized lentivirus expression plasmids for stable overexpression of TMEM14A 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM14A
    Search LifeMap BioReagents cell lines for TMEM14A
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM14A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM14A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for TMEM14A (Q9Y6G13 ENSP000002113144) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREB3O438893I2D: score=1 
    USP18Q9UMW83I2D: score=1 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM14A (TM14A)

    Search CenterWatch for drugs/clinical trials and news about TMEM14A / TM14A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMEM14A gene: 
    NM_014051.3  

    Unigene Cluster for TMEM14A:

    Transmembrane protein 14A
    Hs.94896  [show with all ESTs]
    Unigene Representative Sequence: BF690886
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000211314(uc003pax.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM14A
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM14A:
    hsa-miR-200c hsa-miR-429 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidTMEM14A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMEM14A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM14A
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM14A (see all 7)
    OriGene ORF clones in mouse, rat for TMEM14A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM14A (NM_014051)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM14A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM14A
    Sirion Biotech Customized lentivirus for stable overexpression of TMEM14A 
                         Customized lentivirus expression plasmids for stable overexpression of TMEM14A 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM14A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM14A
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM14A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM14A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM14A

    Additional mRNA sequence: 

    AF239771.1 AK312063.1 BC015097.1 BC019328.1 

    10 DOTS entries:

    DT.91685505  DT.213523  DT.100660623  DT.92435606  DT.40118615  DT.100817795  DT.92435604  DT.95180552 
    DT.95316963  DT.97782406 

    24/160 AceView cDNA sequences (see all 160):

    AI928977 BM785286 AI358016 BX103663 AA029044 CA943679 CR618706 AA811461 
    BQ014279 BE296549 AI358762 BU737656 AI263509 CD370335 BU734097 BC019328 
    CA448163 BM806629 AA883614 AA379956 AW273267 CA867953 BI850372 BF435730 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM14A (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c
    SP1:                                -                       -     -                           
    SP2:                                                        -     -                           
    SP3:                                -     -                 -     -                           
    SP4:                          -     -     -                 -     -                           
    SP5:                                                                                          


    ECgene alternative splicing isoforms for TMEM14A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMEM14A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTCAAGTAA
    TMEM14A Expression
    About this image


    See TMEM14A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMEM14A

    SOURCE GeneReport for Unigene cluster: Hs.94896
        SABiosciences Custom PCR Arrays for TMEM14A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM14A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM14A
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM14A
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM14A
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM14A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM14A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TMEM14A gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem14a1 , 5 transmembrane protein 14A1, 5 89.56(n)1
    92.93(a)1
      1 (6.50 cM)5
    757121  NM_029398.21  NP_083674.21 
     212185755 
    chicken
    (Gallus gallus)
    Aves TMEM14A1 transmembrane protein 14A 67.34(n)
    64.65(a)
      421897  XM_419915.3  XP_419915.3 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM14A6
    Uncharacterized protein
    63(a)
    1 ↔ 1
    1(151855291-151860151)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480349732   -- 74.7(n)    48034973 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1630801 zgc:163080 57.29(n)
    51.04(a)
      799515  NM_001082933.2  NP_001076402.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG55326
    --
    40(a)
    1 → many
    2R(19640264-19640929)


    ENSEMBL Gene Tree for TMEM14A (if available)
    TreeFam Gene Tree for TMEM14A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TMEM14A gene
    TMEM14B2  TMEM14C2  
    3 SIMAP similar genes for TMEM14A using alignment to 2 protein entries:     TM14A_HUMAN (see all proteins):
    TMEM14C    TMEM14B    TMEM14D

    TMEM14A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/409 SNPs in TMEM14A are shown (see all 409)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs717997541,2
    C--52461241(+) ACAAC-/AAAAA 
            
    AAAAA
    1 -- int10--------
    rs73413271,2
    C,H--52534480(+) GGAGAG/CAAGGT 1 -- us2k1 trp34Minor allele frequency- C:0.00NS EA 420
    rs759720041,2
    C,F--52534496(+) GGCTGG/AGGTAA 1 -- us2k11Minor allele frequency- A:0.06NA 120
    rs1488857781,2
    C--52534497(+) GCTGGA/GGTAAG 1 -- us2k10--------
    rs1160126441,2
    F--52534605(+) CAACTC/GTTCTG 1 -- us2k11Minor allele frequency- G:0.04WA 118
    rs1423203011,2
    --52534610(+) CTTCTA/GTGAAT 1 -- us2k10--------
    rs7673081,2
    C,F,H--52534645(-) AAGTTG/AGTCCT 1 -- us2k122Minor allele frequency- A:0.27NS EA NA WA 2526
    rs7673101,2
    H--52534673(-) TATAAC/TTACAT 1 -- us2k14Minor allele frequency- T:0.00NS EA 420
    rs1890666591,2
    --52534683(+) ATTACG/TTCCCT 1 -- us2k10--------
    rs121924451,2
    F--52534701(+) TTTTAC/TGCACA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM14A (52535884 - 52551386 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TMEM14A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv269679CNV Insertion20981092
    esv273125CNV Insertion20981092
    nsv462945CNV Loss19166990
    nsv470818CNV Loss18288195
    nsv830663CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM14A
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM14A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for TMEM14A:    About MalaCards
    juvenile myoclonic epilepsy    idiopathic generalized epilepsy    intrahepatic cholangiocarcinoma    cholangiocarcinoma

    1 disease from the University of Copenhagen DISEASES database for TMEM14A:
    Idiopathic generalized epilepsy

    TMEM14A for disorders           About GeneDecksing

    Genetic Association Database (GAD): TMEM14A

    Export disorders for TMEM14A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM14A gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with TMEM14A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    3. Identifying protein partners of CLN8, an ER-resident p rotein involved in neuronal ceroid lipofuscinosis. (PubMed id 23142642)1 Passantino R....Guarneri P. (2013)
    4. Facile backbone structure determination of human membrane proteins by NMR spectroscopy. (PubMed id 22609626)2 Klammt C.... Choe S. (2012)
    5. TMEM14A inhibits N-(4-hydroxyphenyl)retinamide-induce d apoptosis through the stabilization of mitochondrial membrane potential. (PubMed id 21723035)1 Woo I.S....Seo H.G. (2011)
    6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    8. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (2007)
    9. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 28978 HGNC: 21076 AceView: TMEM14A Ensembl:ENSG00000096092 euGenes: HUgn28978
    ECgene: TMEM14A H-InvDB: TMEM14A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM14A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMEM14A gene:
    Search GeneIP for patents involving TMEM14A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM14A  
     OriGene qPCR primer pairs and template standards for TMEM14A   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM14A  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM14A   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM14A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM14A   OriGene Custom Protein Services for TMEM14A  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMEM14A
     QIAGEN SeqTarget long-range PCR primers for resequencing TMEM14A
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM14A
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM14A
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM14A
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM14A
     GenScript Custom Purified and Recombinant Proteins Services for TMEM14A GenScript cDNA clones with any tag delivered in your preferred vector for TMEM14A
     GenScript Custom Assay Services for TMEM14A GenScript Custom Superior Antibodies Services for TMEM14A
     GenScript Custom overexpressing Cell Line Services for TMEM14A CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TMEM14A promoter
     Search Chromatin IP Primers for TMEM14A
     RT2 qPCR Primer Assay in human, mouse, rat TMEM14A
     Search GNC Networks for TMEM14A
     SABiosciences Custom PCR Arrays for TMEM14A
     Search Tocris compounds for TMEM14A (TM14A)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TMEM14A antibodies
     TMEM14A proteins
     Search for Antibodies for TMEM14A at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TMEM14A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for TMEM14A
     Antibodies for TMEM14A
     ELISAs for TMEM14A
     CLIAs for TMEM14A
     Search LifeMap BioReagents cell lines for TMEM14A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM14A
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM14A
     SwitchGear Promoter luciferase reporter plasmids for TMEM14A
     Search ThermoFisher Antibodies for TMEM14A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM14A
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TMEM14A
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMEM14A
    Customized:
     lentivirus for stable overexpression of TMEM14A
     lentivirus expression plasmids for stable overexpression of TMEM14A
     adenovirus for overexpression of TMEM14A
     Search LSBio for Antibodies for TMEM14A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM14A gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4