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Aliases for TMEM144 Gene

Aliases for TMEM144 Gene

  • Transmembrane Protein 144 2 3 5

External Ids for TMEM144 Gene

Previous GeneCards Identifiers for TMEM144 Gene

  • GC04P159351
  • GC04P159131
  • GC04P154882

Summaries for TMEM144 Gene

GeneCards Summary for TMEM144 Gene

TMEM144 (Transmembrane Protein 144) is a Protein Coding gene. GO annotations related to this gene include carbohydrate transmembrane transporter activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM144 Gene

Genomics for TMEM144 Gene

Regulatory Elements for TMEM144 Gene

Genomic Location for TMEM144 Gene

Chromosome:
4
Start:
158,201,604 bp from pter
End:
158,255,411 bp from pter
Size:
53,808 bases
Orientation:
Plus strand

Genomic View for TMEM144 Gene

Genes around TMEM144 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM144 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM144 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM144 Gene

Proteins for TMEM144 Gene

  • Protein details for TMEM144 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z5S9-TM144_HUMAN
    Recommended name:
    Transmembrane protein 144
    Protein Accession:
    Q7Z5S9
    Secondary Accessions:
    • D3DP24
    • Q49A05
    • Q9NUT3

    Protein attributes for TMEM144 Gene

    Size:
    345 amino acids
    Molecular mass:
    37653 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM144 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM144 Gene

Proteomics data for TMEM144 Gene at MOPED

Post-translational modifications for TMEM144 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM144 Gene

Domains & Families for TMEM144 Gene

Protein Domains for TMEM144 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM144 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7Z5S9

UniProtKB/Swiss-Prot:

TM144_HUMAN :
  • Belongs to the TMEM144 family.
Family:
  • Belongs to the TMEM144 family.
genes like me logo Genes that share domains with TMEM144: view

No data available for Gene Families for TMEM144 Gene

Function for TMEM144 Gene

genes like me logo Genes that share phenotypes with TMEM144: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM144 Gene

Localization for TMEM144 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM144 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM144 Gene COMPARTMENTS Subcellular localization image for TMEM144 gene
Compartment Confidence
mitochondrion 3
plasma membrane 3

No data available for Gene Ontology (GO) - Cellular Components for TMEM144 Gene

Pathways & Interactions for TMEM144 Gene

SuperPathways for TMEM144 Gene

No Data Available

Interacting Proteins for TMEM144 Gene

Gene Ontology (GO) - Biological Process for TMEM144 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM144 Gene

Drugs & Compounds for TMEM144 Gene

No Compound Related Data Available

Transcripts for TMEM144 Gene

Unigene Clusters for TMEM144 Gene

Transmembrane protein 144:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM144 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a ·
SP1: - - - - - - -
SP2: - - - - - - - -
SP3: - - - - -
SP4: - - - - -
SP5: -
SP6: - - - - -
SP7: - - - -
SP8: - - -
SP9: - - - - - -
SP10:
SP11: - - - -
SP12: - - - -
SP13: - -

ExUns: 14b ^ 15
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for TMEM144 Gene

GeneLoc Exon Structure for
TMEM144
ECgene alternative splicing isoforms for
TMEM144

Expression for TMEM144 Gene

mRNA expression in normal human tissues for TMEM144 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM144 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x12.0), Brain - Substantia nigra (x6.7), and Brain - Hippocampus (x4.7).

SOURCE GeneReport for Unigene cluster for TMEM144 Gene Hs.176227

genes like me logo Genes that share expression patterns with TMEM144: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMEM144 Gene

Orthologs for TMEM144 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM144 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM144 35
  • 89.37 (n)
  • 88.99 (a)
TMEM144 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM144 35
  • 91.3 (n)
  • 90.43 (a)
TMEM144 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem144 35
  • 83.19 (n)
  • 86.67 (a)
Tmem144 16
Tmem144 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TMEM144 35
  • 99.23 (n)
  • 99.13 (a)
TMEM144 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem144 35
  • 83.57 (n)
  • 87.25 (a)
oppossum
(Monodelphis domestica)
Mammalia TMEM144 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM144 36
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM144 35
  • 73.47 (n)
  • 69.1 (a)
TMEM144 36
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM144 36
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.16658 35
tmem144 35
  • 69.59 (n)
  • 69.59 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem144a 35
  • 64.32 (n)
  • 65.4 (a)
tmem144a 36
  • 57 (a)
OneToMany
tmem144b 36
  • 50 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea R144.6 35
  • 51.81 (n)
  • 42.77 (a)
F49C12.6 36
  • 33 (a)
OneToMany
K07F5.12 36
  • 30 (a)
OneToMany
R144.6 36
  • 39 (a)
OneToMany
T19A6.4 36
  • 34 (a)
OneToMany
W02D3.4 36
  • 39 (a)
OneToMany
W06A7.4 36
  • 32 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4465 36
  • 41 (a)
OneToOne
Species with no ortholog for TMEM144:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM144 Gene

ENSEMBL:
Gene Tree for TMEM144 (if available)
TreeFam:
Gene Tree for TMEM144 (if available)

Paralogs for TMEM144 Gene

No data available for Paralogs for TMEM144 Gene

Variants for TMEM144 Gene

Sequence variations from dbSNP and Humsavar for TMEM144 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs34277853 - 158,232,957(-) TGGTA(C/T)CCATG reference, missense
rs1328924 -- 158,248,323(+) gctgt(C/T)tggga intron-variant
rs1360066 -- 158,254,462(+) TTTAA(A/G)AAAAC utr-variant-3-prime
rs1360067 -- 158,254,688(+) TTTGA(A/G)ATAAC utr-variant-3-prime
rs1410786 -- 158,221,670(-) CCAGG(A/G)AAGGC intron-variant

Variation tolerance for TMEM144 Gene

Residual Variation Intolerance Score: 33.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.33; 41.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM144 Gene

HapMap Linkage Disequilibrium report
TMEM144

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM144 Gene

Disorders for TMEM144 Gene

Relevant External Links for TMEM144

Genetic Association Database (GAD)
TMEM144
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM144

No disorders were found for TMEM144 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM144 Gene

Publications for TMEM144 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for TMEM144 Gene

Sources for TMEM144 Gene

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