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Aliases for TMEM144 Gene

Aliases for TMEM144 Gene

  • Transmembrane Protein 144 2 3

External Ids for TMEM144 Gene

Previous GeneCards Identifiers for TMEM144 Gene

  • GC04P159351
  • GC04P159131
  • GC04P154882

Summaries for TMEM144 Gene

GeneCards Summary for TMEM144 Gene

TMEM144 (Transmembrane Protein 144) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM144 Gene

Genomics for TMEM144 Gene

Regulatory Elements for TMEM144 Gene

Genomic Location for TMEM144 Gene

Start:
158,201,597 bp from pter
End:
158,255,411 bp from pter
Size:
53,815 bases
Orientation:
Plus strand

Genomic View for TMEM144 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM144 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM144 Gene

Proteins for TMEM144 Gene

  • Protein details for TMEM144 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z5S9-TM144_HUMAN
    Recommended name:
    Transmembrane protein 144
    Protein Accession:
    Q7Z5S9
    Secondary Accessions:
    • D3DP24
    • Q49A05
    • Q9NUT3

    Protein attributes for TMEM144 Gene

    Size:
    345 amino acids
    Molecular mass:
    37653 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM144 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM144 Gene

Proteomics data for TMEM144 Gene at MOPED

Post-translational modifications for TMEM144 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM144 Gene

Domains for TMEM144 Gene

Protein Domains for TMEM144 Gene

Suggested Antigen Peptide Sequences for TMEM144 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7Z5S9

UniProtKB/Swiss-Prot:

TM144_HUMAN :
  • Q7Z5S9
Family:
  • Belongs to the TMEM144 family.
genes like me logo Genes that share domains with TMEM144: view

No data available for Gene Families for TMEM144 Gene

Function for TMEM144 Gene

Gene Ontology (GO) - Molecular Function for TMEM144 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015144 carbohydrate transmembrane transporter activity --
genes like me logo Genes that share ontologies with TMEM144: view

Phenotypes for TMEM144 Gene

GenomeRNAi human phenotypes for TMEM144:
genes like me logo Genes that share phenotypes with TMEM144: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM144 Gene

Localization for TMEM144 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM144 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM144 Gene COMPARTMENTS Subcellular localization image for TMEM144 gene
Compartment Confidence
plasma membrane 3
nucleus 1

Gene Ontology (GO) - Cellular Components for TMEM144 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM144: view

Pathways for TMEM144 Gene

SuperPathways for TMEM144 Gene

No Data Available

Interacting Proteins for TMEM144 Gene

Gene Ontology (GO) - Biological Process for TMEM144 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0034219 carbohydrate transmembrane transport --
genes like me logo Genes that share ontologies with TMEM144: view

No data available for Pathways by source for TMEM144 Gene

Transcripts for TMEM144 Gene

Unigene Clusters for TMEM144 Gene

Transmembrane protein 144:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM144

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM144 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a ·
SP1: - - - - - - -
SP2: - - - - - - - -
SP3: - - - - -
SP4: - - - - -
SP5: -
SP6: - - - - -
SP7: - - - -
SP8: - - -
SP9: - - - - - -
SP10:
SP11: - - - -
SP12: - - - -
SP13: - -

ExUns: 14b ^ 15
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for TMEM144 Gene

GeneLoc Exon Structure for
TMEM144
ECgene alternative splicing isoforms for
TMEM144

Expression for TMEM144 Gene

mRNA expression in normal human tissues for TMEM144 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM144 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (12.0), Brain - Substantia nigra (6.7), and Brain - Hippocampus (4.7).

SOURCE GeneReport for Unigene cluster for TMEM144 Gene Hs.176227

genes like me logo Genes that share expressions with TMEM144: view

In Situ Assay Products

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for TMEM144 Gene

Orthologs for TMEM144 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM144 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM144 35
  • 99.23 (n)
  • 99.13 (a)
TMEM144 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM144 35
  • 89.37 (n)
  • 88.99 (a)
TMEM144 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM144 35
  • 91.3 (n)
  • 90.43 (a)
TMEM144 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem144 35
  • 83.19 (n)
  • 86.67 (a)
Tmem144 16
Tmem144 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM144 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM144 36
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem144 35
  • 83.57 (n)
  • 87.25 (a)
chicken
(Gallus gallus)
Aves TMEM144 35
  • 73.47 (n)
  • 69.1 (a)
TMEM144 36
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM144 36
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.16658 35
tmem144 35
  • 69.59 (n)
  • 69.59 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem144a 35
  • 64.32 (n)
  • 65.4 (a)
tmem144a 36
  • 57 (a)
OneToMany
tmem144b 36
  • 50 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F49C12.6 36
  • 33 (a)
OneToMany
K07F5.12 36
  • 30 (a)
OneToMany
R144.6 35
  • 51.81 (n)
  • 42.77 (a)
R144.6 36
  • 39 (a)
OneToMany
T19A6.4 36
  • 34 (a)
OneToMany
W02D3.4 36
  • 39 (a)
OneToMany
W06A7.4 36
  • 32 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4465 36
  • 41 (a)
OneToOne
Species with no ortholog for TMEM144:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM144 Gene

ENSEMBL:
Gene Tree for TMEM144 (if available)
TreeFam:
Gene Tree for TMEM144 (if available)

Paralogs for TMEM144 Gene

No data available for Paralogs for TMEM144 Gene

Variants for TMEM144 Gene

Sequence variations from dbSNP and Humsavar for TMEM144 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs1047725 -- 158,254,957(+) TAGTT(A/C)AAATC utr-variant-3-prime
rs1328924 -- 158,248,323(+) gctgt(C/T)tggga intron-variant
rs1360066 -- 158,254,462(+) TTTAA(A/G)AAAAC utr-variant-3-prime
rs1360067 -- 158,254,688(+) TTTGA(A/G)ATAAC utr-variant-3-prime
rs1410786 -- 158,221,670(-) CCAGG(A/G)AAGGC intron-variant

Relevant External Links for TMEM144 Gene

HapMap Linkage Disequilibrium report
TMEM144

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM144 Gene

Disorders for TMEM144 Gene

Relevant External Links for TMEM144

Genetic Association Database (GAD)
TMEM144
genes like me logo Genes that share disorders with TMEM144: view

No data available for UniProtKB/Swiss-Prot for TMEM144 Gene

Publications for TMEM144 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Genome-wide association with diabetes-related traits in the Framingham Heart Study. (PMID: 17903298) Meigs J.B. … Dupuis J. (BMC Med. Genet. 2007) 48
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TMEM144 Gene

  • antibodies-online peptides for TMEM144
  • antibodies-online antibodies for TMEM144
  • antibodies-online kits for TMEM144

Sources for TMEM144 Gene

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