Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM139 Gene

protein-coding   GIFtS: 41
GCID: GC07P142977

Transmembrane Protein 139

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 1391 2

External Ids:    HGNC: 220581   Entrez Gene: 1359322   Ensembl: ENSG000001788267   UniProtKB: Q8IV313   

Export aliases for TMEM139 gene to outside databases

Previous GC identifers: GC07P142687 GC07P137319


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM139 Gene:
TMEM139 (transmembrane protein 139) is a protein-coding gene. Diseases associated with TMEM139 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM139 gene promoter:
         SRF   TBP   AML1a   SRF (504 AA)   Meis-1b   E47   TFIID   Meis-1a   ZIC2/Zic2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TMEM139 promoter sequence
   Search Chromatin IP Primers for TMEM139

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM139


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q34   Ensembl cytogenetic band:  7q34   HGNC cytogenetic band: 7q34

TMEM139 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM139 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P142977:  view genomic region     (about GC identifiers)

Start:
142,977,050 bp from pter      End:
142,985,141 bp from pter
Size:
8,092 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 142,384,156-142,387,257     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TM139_HUMAN, Q8IV31 (See protein sequence)
Recommended Name: Transmembrane protein 139 precursor  
Size: 216 amino acids; 23729 Da
Sequence caution: Sequence=AAH16719.1; Type=Erroneous initiation;
Secondary accessions: B2RCL5 D3DXD4 Q6ZME2 Q8NC22 Q96AU8

Explore the universe of human proteins at neXtProt for TMEM139: NX_Q8IV31

Explore proteomics data for TMEM139 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMEM139 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001229702.1  NP_001229703.1  NP_001229704.1  NP_001269805.1  NP_001269806.1  NP_699176.1  

    ENSEMBL proteins: 
     ENSP00000386879   ENSP00000352284   ENSP00000386335   ENSP00000387044   ENSP00000386564  

    TMEM139 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMEM139
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM139
    GenScript Custom Purified and Recombinant Proteins Services for TMEM139
    Novus Biologicals TMEM139 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM139

    TMEM139 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM139
    Novus Biologicals TMEM139 Antibodies
    Abcam antibodies for TMEM139
    Cloud-Clone Corp. Antibodies for TMEM139
    Search ThermoFisher Antibodies for TMEM139
    LSBio Antibodies in human, mouse, rat for TMEM139

    TMEM139 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM139
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM139
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM139
    Cloud-Clone Corp. CLIAs for TMEM139


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus

    ProtoNet protein and cluster: Q8IV31


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 MGI phenotypic allele for Tmem139 (no phenotypes)

    TMEM139 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tmem139tm1Lex for TMEM139

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM139
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM139

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM139
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM139

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TMEM139 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate TMEM139:
    hsa-miR-642b hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidTMEM139 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM139
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM139

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM139

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM139 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM139
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM139 (NM_153345)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM139
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM139

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM139
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM139 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM139


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TM139_HUMAN, Q8IV31: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    plasma membrane2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    TMEM139 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM139
    Interactions:

        Search GeneGlobe Interaction Network for TMEM139

    1 Interacting protein for TMEM139 (Q8IV312, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMURF2Q9HAU42, 3MINT-61803 I2D: score=3 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM139 (TM139)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM139 gene (6 alternative transcripts): 
    NM_001242773.2  NM_001242774.2  NM_001242775.2  NM_001282876.1  NM_001282877.1  NM_153345.3  

    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409102 ENST00000487419 ENST00000359333(uc022aoc.1 uc010lov.3 uc003wck.4 uc003wcn.3 uc022aod.1 uc003wcm.3)
    ENST00000480421 ENST00000409244 ENST00000409541 ENST00000410004(uc003wcl.3)
    ENST00000482420 ENST00000471161
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM139 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate TMEM139:
    hsa-miR-642b hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidTMEM139 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM139
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM139
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM139 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM139
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM139 (NM_153345)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM139
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM139
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM139
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM139
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM139
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM139
      QuantiFast Probe-based Assays in human, mouse, rat TMEM139

    Selected AceView cDNA sequences (see all 92):

    BM818467 AY358781 AL549843 AW058583 AI984393 AK075067 CB142336 CB241413 
    AW138330 BC035517 BE018738 BM719883 CB156055 BC048333 BC035888 CD674062 
    BM995528 BM676746 CA439205 BI772441 AW614080 NM_153345 AA872608 BG402914 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM139 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e
    SP1:                    -                                                   
    SP2:                    -           -                                       
    SP3:        -     -     -     -     -                                       
    SP4:                    -           -     -                                 
    SP5:                                -                                       


    ECgene alternative splicing isoforms for TMEM139

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM139 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCCTCCCC
    TMEM139 Expression
    About this image

    TMEM139 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM139 Protein Expression
        Custom PCR Arrays for TMEM139
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM139
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM139
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM139
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM139
    QuantiFast Probe-based Assays in human, mouse, rat TMEM139
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM139

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM139 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1391 , 5 transmembrane protein 1391, 5 72.96(n)1
    58.02(a)1
      6 (20.54 cM)5
    1092181  NM_175408.41  NP_780617.21 
     422619705 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM1396
    transmembrane protein 139
    31(a)
    1 ↔ 1
    GL343381.1(11550-33962)


    ENSEMBL Gene Tree for TMEM139 (if available)
    TreeFam Gene Tree for TMEM139 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM139 (see all 60)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1930096451,2
    --142980071(+) TTGAGC/TGAAAT 7 -- us2k10--------
    rs1389140621,2
    C--142980180(+) AATAAC/GGTCTT 7 -- us2k10--------
    rs10059261,2
    C,H--142980267(-) ACTGTC/TCACAT 7 -- us2k15Minor allele frequency- T:0.00NS EA NA 418
    rs284780731,2
    C,F--142980292(+) TAAACG/ATTTTA 7 -- us2k11Minor allele frequency- A:0.04WA 118
    rs2010998141,2
    --142980382(+) ACAAA-/TGCAATTT 7 -- us2k10--------
    rs1420454631,2
    --142980615(+) CCCACA/CACTCA 7 -- us2k10--------
    rs1504191611,2
    --142980686(+) ATTCAC/TATGTT 7 -- us2k10--------
    rs1138194061,2
    F--142980690(+) ATATGC/TTAACT 7 -- us2k11Minor allele frequency- T:0.00CSA 1
    rs1496075031,2
    --142980873(+) GCTATC/TGATCT 7 -- us2k10--------
    rs1836541141,2
    --142980936(+) CCACTA/GCAGAC 7 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM139 (142977050 - 142985141 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TMEM139:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv831169CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM139
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM139

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    3 diseases for TMEM139:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    parkinson's disease


    TMEM139 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TMEM139
    Human Genome Epidemiology (HuGE) Navigator: TMEM139 (1 document)

    Export disorders for TMEM139 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM139 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with TMEM139)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    8. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (Biochem. Biophys. Res. Commun. 2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)1 Kim J.M.... Kim N.S. (DNA Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 135932 HGNC: 22058 AceView: FLJ90586 Ensembl:ENSG00000178826 euGenes: HUgn135932
    ECgene: TMEM139 H-InvDB: TMEM139

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM139 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM139 gene:
    Search GeneIP for patents involving TMEM139

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM139  
     OriGene qPCR primer pairs and template standards for TMEM139   OriGene Protein Over-expression Lysate for TMEM139  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM139  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM139   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM139   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM139   OriGene Custom Protein Services for TMEM139  

     
     
     Block miRNA regulation of human, mouse, rat TMEM139 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM139
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM139 Predesigned siRNA for gene silencing in human, mouse, rat TMEM139
     QuantiFast Probe-based Assays in human, mouse, rat TMEM139 QuantiTect SYBR Green Assays in human, mouse, rat TMEM139
     Custom PCR Arrays for TMEM139 Search Chromatin IP Primers for TMEM139
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM139  Search GeneGlobe Interaction Network for TMEM139
     Regulatory tfbs in TMEM139 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM139 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM139
     GenScript Custom Assay Services for TMEM139 GenScript Custom overexpressing Cell Line Services for TMEM139
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM139 (TM139)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM139 antibodies
     TMEM139 lysates
     Antibodies for TMEM139
     See all of Abcam's Antibodies, Kits and Proteins for TMEM139
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM139
     Antibodies for TMEM139
     ELISAs for TMEM139
     CLIAs for TMEM139



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM139
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM139
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM139
     SwitchGear Promoter luciferase reporter plasmids for TMEM139
     Search ThermoFisher Antibodies for TMEM139
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM139
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM139
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM139
     LSBio Antibodies in human, mouse, rat for TMEM139
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM139 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4