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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM138 Gene

protein-coding   GIFtS: 45
GCID: GC11P061129

Transmembrane Protein 138

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Transmembrane Protein 1381 2

External Ids:    HGNC: 269441   Entrez Gene: 515242   Ensembl: ENSG000001494837   OMIM: 6144595   UniProtKB: Q9NPI03   
ORGUL members:         
NONCODE14:n408276      

Export aliases for TMEM138 gene to outside databases

Previous GC identifers: GC11P060887 GC11P057458


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TMEM138 Gene:
This gene encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes
short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the
neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental
disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Mar
2012)

GeneCards Summary for TMEM138 Gene: 
TMEM138 (transmembrane protein 138) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with TMEM138 include tmem138-related joubert syndrome, and apraxia.

UniProtKB/Swiss-Prot: TM138_HUMAN, Q9NPI0
Function: Required for ciliogenesis

Gene Wiki entry for TMEM138 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM138 gene promoter:
         NF-1   NF-kappaB   YY1   CREB   deltaCREB   NF-kappaB2   STAT3   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM138 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMEM138

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM138


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.2   Ensembl cytogenetic band:  11q12.2   HGNC cytogenetic band: 11q12.2

TMEM138 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM138 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P061129:  view genomic region     (about GC identifiers)

Start:
61,129,473 bp from pter      End:
61,136,981 bp from pter
Size:
7,509 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TM138_HUMAN, Q9NPI0 (See protein sequence)
Recommended Name: Transmembrane protein 138  
Size: 162 amino acids; 19262 Da
Subcellular location: Vacuole membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes to
vesicles en route to the base of cilium
Miscellaneous: TMEM138 and TMEM216 genes are adjacent and are aligned in a head-to-tail configuration. They share
some cis regulatory region and display coordinated expression. Genes were joined by chromoaomal rearrangement at
the amphiboan to reptile evolutionary transition around 340 million years ago (PubMed:22282472)
Sequence caution: Sequence=CAI46174.1; Type=Frameshift; Positions=101;
Secondary accessions: A6NGA7 B4E044 Q5JPE1
Alternative splicing: 3 isoforms:  Q9NPI0-1   Q9NPI0-2   Q9NPI0-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM138: NX_Q9NPI0

Explore proteomics data for TMEM138 at MOPED 

TMEM138 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

TMEM138 Protein Expression

REFSEQ proteins: NP_057548.1  
ENSEMBL proteins: 
 ENSP00000278826   ENSP00000445792   ENSP00000371206  

Human Recombinant Protein Products for TMEM138: 
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OriGene Protein Over-expression Lysate for TMEM138
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Novus Biologicals TMEM138 Protein
Novus Biologicals TMEM138 Lysate
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Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for TMEM138 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005774vacuolar membrane IEA--
GO:0005929cilium IDA--
GO:0016021integral to membrane IEA--

TMEM138 for ontologies           About GeneDecksing



TMEM138 Antibody Products: 
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LSBio Antibodies in human, mouse, rat for TMEM138 

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Cloud-Clone Corp. ELISAs for TMEM138 
Cloud-Clone Corp. CLIAs for TMEM138


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro protein domain:
 IPR024133 TM_138

Graphical View of Domain Structure for InterPro Entry Q9NPI0

ProtoNet protein and cluster: Q9NPI0

UniProtKB/Swiss-Prot: TM138_HUMAN, Q9NPI0
Similarity: Belongs to the TMEM138 family


TMEM138 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: TM138_HUMAN, Q9NPI0
Function: Required for ciliogenesis

Animal Models:

   inGenious Targeting Laboratory - Custom generated mouse model solutions for TMEM138 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMEM138

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM138 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM138 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM138
5 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM138:
hsa-miR-3163 hsa-miR-1252 hsa-miR-4302 hsa-miR-340 hsa-miR-1248
SwitchGear 3'UTR luciferase reporter plasmidTMEM138 3' UTR sequence
Inhib. RNA
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Gene Editing
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Sirion Biotech Customized adenovirus for overexpression of TMEM138

Clone
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OriGene clones in human, mouse for TMEM138 (see all 7)
OriGene ORF clones in mouse, rat for TMEM138
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: TMEM138 (NM_016464)
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM138
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM138
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Cell Line
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Search LifeMap BioReagents cell lines for TMEM138
In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM138


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM138

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0042384cilium assembly IMP--

TMEM138 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMEM138 (TM138)

Search CenterWatch for drugs/clinical trials and news about TMEM138 / TM138

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TMEM138 gene: 
NM_016464.4  

Unigene Cluster for TMEM138:

Transmembrane protein 138
Hs.406530  [show with all ESTs]
Unigene Representative Sequence: AL832879
12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000278826(uc021qke.1 uc001nrl.2) ENST00000534963 ENST00000543594
ENST00000542946 ENST00000540194 ENST00000507563(uc010rli.2) ENST00000423772
ENST00000451389 ENST00000545420 ENST00000381787 ENST00000539776 ENST00000543833

miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM138
5 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM138:
hsa-miR-3163 hsa-miR-1252 hsa-miR-4302 hsa-miR-340 hsa-miR-1248
SwitchGear 3'UTR luciferase reporter plasmidTMEM138 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for TMEM138
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM138
Clone
Products:
     
OriGene clones in human, mouse for TMEM138 (see all 7)
OriGene ORF clones in mouse, rat for TMEM138
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: TMEM138 (NM_016464)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM138
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM138
Sirion Biotech Customized lentivirus for stable overexpression of TMEM138 
                     Customized lentivirus expression plasmids for stable overexpression of TMEM138 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for TMEM138
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM138
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM138
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM138
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM138

Additional mRNA sequence: 

AF151030.1 AF151032.1 AK027724.1 AK307371.1 AL832879.1 BC005201.1 NR_028473.1 

24 DOTS entries:

DT.97860343  DT.418132  DT.100879116  DT.97820214  DT.100879131  DT.100879111  DT.100879120  DT.100879128 
DT.40280039  DT.102839521  DT.91767868  DT.95126757  DT.100867732  DT.100879122  DT.100879126  DT.120694348 
DT.120694414  DT.100715194  DT.120694328  DT.120694312  DT.120694425  DT.453250  DT.95126755  DT.120694196 

24/305 AceView cDNA sequences (see all 305):

BX362853 BM663427 BI061739 AA565986 CD366255 C20821 CA487416 CA454789 
BI063556 CD742673 CD671256 CD105386 CD368121 BQ421457 BG109406 AI927381 
CR596588 AF151032 AA253341 BM708169 CR602992 AI804016 N39763 AI076123 

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM138 (see all 11)    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d
SP1:                                -     -           -     -           -     -                                       
SP2:                                -     -           -     -           -     -                                       
SP3:                                -     -           -     -           -     -                                       
SP4:                                -     -           -     -           -     -                                       
SP5:                                -     -           -     -           -                                             


ECgene alternative splicing isoforms for TMEM138

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMEM138 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGCAAACAGC
TMEM138 Expression
About this image


See TMEM138 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM138

SOURCE GeneReport for Unigene cluster: Hs.406530
    SABiosciences Custom PCR Arrays for TMEM138
Primer
Products:
OriGene qPCR primer pairs and template standards for TMEM138
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM138
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM138
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM138
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM138
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM138

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TMEM138 gene from 7/17 species (see all 17)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tmem1381 , 5 transmembrane protein 1381, 5 89.71(n)1
91.98(a)1
  19 (6.60 cM)5
729821  NM_028411.31  NP_082687.11 
 105708855 
chicken
(Gallus gallus)
Aves TMEM1381 transmembrane protein 138 79.09(n)
83.23(a)
  426323  XM_423984.3  XP_423984.3 
lizard
(Anolis carolinensis)
Reptilia TMEM1386
Uncharacterized protein
83(a)
1 ↔ 1
GL343235.1(838946-844877)
African clawed frog
(Xenopus laevis)
Amphibia Xl.323862 Xenopus laevis transcribed sequence with weak similarity more 76.48(n)    BJ615922.1 
zebrafish
(Danio rerio)
Actinopterygii tmem1381 transmembrane protein 138 67.49(n)
67.9(a)
  100332440  XM_002666770.1  XP_002666816.1 
fruit fly
(Drosophila melanogaster)
Insecta CG139991 CG13999 46.27(n)
32.89(a)
  33826  NM_135128.3  NP_608972.1 
worm
(Caenorhabditis elegans)
Secernentea F10B5.91 Protein F10B5.9 45.51(n)
31.41(a)
  3565047  NM_001026903.1  NP_001022074.1 


ENSEMBL Gene Tree for TMEM138 (if available)
TreeFam Gene Tree for TMEM138 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/180 SNPs in TMEM138 are shown (see all 180)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0670604
Joubert syndrome 16 (JBTS16)4--see VAR_0670602 A T mis40--------
VAR_0670614
Joubert syndrome 16 (JBTS16)4--see VAR_0670612 A V mis40--------
VAR_0670624
Joubert syndrome 16 (JBTS16)4--see VAR_0670622 Y C mis40--------
VAR_0670594
Joubert syndrome 16 (JBTS16)4--see VAR_0670592 H R mis40--------
rs1506339441,2
--61047803(+) AGAGAC/TAGACT 2 -- us2k10--------
rs1388390731,2
C--61047908(+) GGCATC/GCACCT 2 -- us2k10--------
rs1919672241,2
--61048043(+) ACAAAA/CCAAAA 2 -- us2k10--------
rs1842301671,2
--61048198(+) TCCAGA/GTAGTA 2 -- us2k10--------
rs1493476431,2
--61048247(+) CTATGA/TCATCA 2 -- us2k10--------
rs1877343651,2
--61048321(+) AGTAAC/TATTTA 2 -- us2k10--------

HapMap Linkage Disequilibrium report for TMEM138 (61129473 - 61136981 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for TMEM138: --

Human Gene Mutation Database (HGMD): TMEM138
SABiosciences Cancer Mutation PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing TMEM138
DNA2.0 Custom Variant and Variant Library Synthesis for TMEM138

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 614459    OMIM disorders: --

UniProtKB/Swiss-Prot: TM138_HUMAN, Q9NPI0
  • Joubert syndrome 16 (JBTS16) [MIM:614465]: An autosomal recessive disorder characterized by oculomotor
    apraxia, variable coloboma, and rare kidney involvement. Neuroradiologically, it is characterized by an
    abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth
    sign). Additional variable features include retinal dystrophy and polydactyly. Note=The disease is caused by
    mutations affecting the gene represented in this entry

  • 8 diseases for TMEM138:    About MalaCards
    tmem138-related joubert syndrome    apraxia    joubert syndrome    joubert syndrome and related disorders
    hypotonia    cerebellar ataxia    ataxia    retinitis


    TMEM138 for disorders           About GeneDecksing


    Export disorders for TMEM138 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM138 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TMEM138)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. (PubMed id 22282472)1, 2 Lee J.H.... Gleeson J.G. (2012)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    4. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    5. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Joubert Syndrome (PubMed id 20301500)1 Parisi M. and Glass I. (1993)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51524 HGNC: 26944 AceView: HSPC196 Ensembl:ENSG00000149483 euGenes: HUgn51524
    ECgene: TMEM138 H-InvDB: TMEM138

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM138 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMEM138 gene:
    Search GeneIP for patents involving TMEM138

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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