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Aliases for TMEM134 Gene

Aliases for TMEM134 Gene

  • Transmembrane Protein 134 2 3

External Ids for TMEM134 Gene

Summaries for TMEM134 Gene

GeneCards Summary for TMEM134 Gene

TMEM134 (Transmembrane Protein 134) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM134 Gene

Genomics for TMEM134 Gene

Genomic Location for TMEM134 Gene

Start:
67,461,710 bp from pter
End:
67,469,277 bp from pter
Size:
7,568 bases
Orientation:
Minus strand

Genomic View for TMEM134 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM134 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM134 Gene

Regulatory Elements for TMEM134 Gene

Proteins for TMEM134 Gene

  • Protein details for TMEM134 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H6X4-TM134_HUMAN
    Recommended name:
    Transmembrane protein 134
    Protein Accession:
    Q9H6X4
    Secondary Accessions:
    • Q08AK4
    • Q6PJN3

    Protein attributes for TMEM134 Gene

    Size:
    195 amino acids
    Molecular mass:
    21586 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM134 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM134 Gene

Proteomics data for TMEM134 Gene at MOPED

Post-translational modifications for TMEM134 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM134 Gene

Domains for TMEM134 Gene

Protein Domains for TMEM134 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

TM134_HUMAN
Family:
  • Belongs to the TMEM134/TMEM230 family.:
    • Q9H6X4
genes like me logo Genes that share domains with TMEM134: view

No data available for Gene Families for TMEM134 Gene

Function for TMEM134 Gene

Phenotypes for TMEM134 Gene

genes like me logo Genes that share phenotypes with TMEM134: view

miRNA for TMEM134 Gene

miRTarBase miRNAs that target TMEM134

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM134 Gene

Localization for TMEM134 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM134 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM134 Gene COMPARTMENTS Subcellular localization image for TMEM134 gene
Compartment Confidence
plasma membrane 3
cytosol 1

Gene Ontology (GO) - Cellular Components for TMEM134 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM134: view

Pathways for TMEM134 Gene

SuperPathways for TMEM134 Gene

No Data Available

Interacting Proteins for TMEM134 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000312615%0d%0a9606.ENSP00000328182%0d%0a9606.ENSP00000378426%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000312615 for TMEM134 Gene via STRING

Gene Ontology (GO) - Biological Process for TMEM134 Gene

None

No data available for Pathways by source for TMEM134 Gene

Transcripts for TMEM134 Gene

Unigene Clusters for TMEM134 Gene

Transmembrane protein 134:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM134 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b ·
SP1: - - - - - - - - - -
SP2: - - - - - - - -
SP3: - - - - - - - - -
SP4: - - - - - - - - - - -
SP5: - - - - - - - - - -
SP6: - - - - - - - - - - -
SP7: - - - - - - - - - - -
SP8: - - - - - - - - -
SP9: - - - - - - -
SP10: - - - - - - -
SP11: - - - -
SP12: - - - - - - - - -
SP13: - - -
SP14: - -
SP15: - - - - - - - - - - - - -
SP16: - - - -
SP17: - - -
SP18: - -
SP19:
SP20: -

ExUns: 8c · 8d · 8e · 8f · 8g · 8h · 8i
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:

Relevant External Links for TMEM134 Gene

GeneLoc Exon Structure for
TMEM134
ECgene alternative splicing isoforms for
TMEM134

Expression for TMEM134 Gene

mRNA expression in normal human tissues for TMEM134 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM134 Gene

SOURCE GeneReport for Unigene cluster for TMEM134 Gene Hs.288761

genes like me logo Genes that share expressions with TMEM134: view

Orthologs for TMEM134 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM134 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM134 36
  • 100 (n)
  • 100 (a)
TMEM134 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM134 36
  • 92.41 (n)
  • 93.33 (a)
TMEM134 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM134 36
  • 93.73 (n)
  • 92.47 (a)
TMEM134 37
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem134 36
  • 90.94 (n)
  • 93.33 (a)
Tmem134 16
oppossum
(Monodelphis domestica)
Mammalia TMEM134 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem134 36
  • 89.23 (n)
  • 92.31 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem134 36
  • 56.74 (n)
  • 57.45 (a)
tmem134 37
  • 51 (a)
OneToOne
zgc64040 36
fruit fly
(Drosophila melanogaster)
Insecta CG12025 37
  • 31 (a)
OneToOne
Species with no ortholog for TMEM134:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM134 Gene

ENSEMBL:
Gene Tree for TMEM134 (if available)
TreeFam:
Gene Tree for TMEM134 (if available)

Paralogs for TMEM134 Gene

Selected SIMAP similar genes for TMEM134 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with TMEM134: view

No data available for Paralogs for TMEM134 Gene

Variants for TMEM134 Gene

Sequence variations from dbSNP and Humsavar for TMEM134 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs949250 -- 67,466,807(+) TCTGA(C/G)CAATG intron-variant
rs949257 -- 67,466,388(+) TATGA(G/T)GGGGG intron-variant
rs1047149 -- 67,464,416(+) CGGCC(A/C)GAGAA utr-variant-3-prime, nc-transcript-variant
rs1062732 -- 67,464,641(+) TAGAA(A/G)AACTG reference, synonymous-codon, nc-transcript-variant
rs1628442 -- 67,471,161(+) CGCAC(C/T)GTCAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TMEM134 Gene

Variant ID Type Subtype PubMed ID
nsv897797 CNV Loss 21882294
nsv897801 CNV Loss 21882294
dgv1193n71 CNV Loss 21882294
dgv1194n71 CNV Loss 21882294
nsv521723 CNV Loss 19592680
nsv468604 CNV Loss 19166990
nsv527056 CNV Loss 19592680
esv2422195 CNV Duplication 17116639

Relevant External Links for TMEM134 Gene

HapMap Linkage Disequilibrium report
TMEM134

Disorders for TMEM134 Gene

Relevant External Links for TMEM134

Genetic Association Database (GAD)
TMEM134
genes like me logo Genes that share disorders with TMEM134: view

No data available for UniProtKB/Swiss-Prot for TMEM134 Gene

Publications for TMEM134 Gene

  1. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 3
  2. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for TMEM134 Gene

Sources for TMEM134 Gene

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