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Aliases for TMEM133 Gene

Aliases for TMEM133 Gene

  • Transmembrane Protein 133 2 3 5
  • AD031 3

External Ids for TMEM133 Gene

Previous GeneCards Identifiers for TMEM133 Gene

  • GC11P100371
  • GC11P100862
  • GC11P096799

Summaries for TMEM133 Gene

Entrez Gene Summary for TMEM133 Gene

  • There is evidence that this intronless gene is transcribed but the protein is predicted. The gene function is unknown. [provided by RefSeq, Jul 2008]

GeneCards Summary for TMEM133 Gene

TMEM133 (Transmembrane Protein 133) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM133 Gene

Genomics for TMEM133 Gene

Regulatory Elements for TMEM133 Gene

Enhancers for TMEM133 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM133 on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM133 Gene

100,991,989 bp from pter
100,993,941 bp from pter
1,953 bases
Plus strand

Genomic View for TMEM133 Gene

Genes around TMEM133 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM133 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM133 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM133 Gene

Proteins for TMEM133 Gene

  • Protein details for TMEM133 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 133
    Protein Accession:

    Protein attributes for TMEM133 Gene

    129 amino acids
    Molecular mass:
    14539 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM133 Gene

Proteomics data for TMEM133 Gene at MOPED

Post-translational modifications for TMEM133 Gene

No Post-translational modifications

Other Protein References for TMEM133 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM133 Gene

Domains & Families for TMEM133 Gene

Protein Domains for TMEM133 Gene


Suggested Antigen Peptide Sequences for TMEM133 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM133: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM133 Gene

Function for TMEM133 Gene

genes like me logo Genes that share phenotypes with TMEM133: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM133 Gene

Localization for TMEM133 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM133 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM133 Gene COMPARTMENTS Subcellular localization image for TMEM133 gene
Compartment Confidence
extracellular 3
cytosol 2
mitochondrion 1
nucleus 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for TMEM133 Gene

Pathways & Interactions for TMEM133 Gene

SuperPathways for TMEM133 Gene

No Data Available

Interacting Proteins for TMEM133 Gene

Gene Ontology (GO) - Biological Process for TMEM133 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM133 Gene

Drugs & Compounds for TMEM133 Gene

No Compound Related Data Available

Transcripts for TMEM133 Gene

mRNA/cDNA for TMEM133 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(78) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM133 Gene

Transmembrane protein 133:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM133 Gene

No ASD Table

Relevant External Links for TMEM133 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM133 Gene

mRNA expression in normal human tissues for TMEM133 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for TMEM133 Gene Hs.44004

genes like me logo Genes that share expression patterns with TMEM133: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMEM133 Gene

Orthologs for TMEM133 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TMEM133 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TMEM133 35
  • 98.97 (n)
  • 96.9 (a)
TMEM133 36
  • 97 (a)
Species with no ortholog for TMEM133:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM133 Gene

Gene Tree for TMEM133 (if available)
Gene Tree for TMEM133 (if available)

Paralogs for TMEM133 Gene

No data available for Paralogs for TMEM133 Gene

Variants for TMEM133 Gene

Sequence variations from dbSNP and Humsavar for TMEM133 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs535443 -- 100,992,925(+) AGAGA(C/T)GCCAA utr-variant-3-prime
rs1047624 -- 100,993,002(+) AAAAA(C/G)CAGAG utr-variant-3-prime
rs2105673 -- 100,992,886(-) ATGGG(A/C)TGGGC utr-variant-3-prime
rs61995873 -- 100,992,588(+) GTCTC(A/C)ATTTC reference, missense
rs61995874 -- 100,992,366(+) ACGAA(A/G)AAGAA reference, missense

Variation tolerance for TMEM133 Gene

Residual Variation Intolerance Score: 71.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.03; 50.25% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for TMEM133 Gene

Disorders for TMEM133 Gene

Relevant External Links for TMEM133

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TMEM133 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM133 Gene

Publications for TMEM133 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. (PMID: 21909110) Wain L.V. … van Duijn C.M. (Nat. Genet. 2011) 3
  4. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. (PMID: 21909115) . … Johnson T. (Nature 2011) 3

Products for TMEM133 Gene

Sources for TMEM133 Gene