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TMEM132A Gene

protein-coding   GIFtS: 49
GCID: GC11P060691

Transmembrane Protein 132A

(Previous names: heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)...)
(Previous symbol: HSPA5BP1)
  Search for TMEM132A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 132A1 2     Glucose-Regulated Protein, 78kDa2
HSPA5BP11 2 3     GRP78-Binding Protein2
Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) Binding
Protein 11 2
     Heat Shock 70kDa Protein 5 Binding Protein 12
HSPA5-Binding Protein 12 3     KIAA15833
GBP2     

External Ids:    HGNC: 310921   Entrez Gene: 549722   Ensembl: ENSG000000061187   UniProtKB: Q24JP53   

Export aliases for TMEM132A gene to outside databases

Previous GC identifers: GC11P060449 GC11P057038


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TMEM132A Gene:
This gene encodes a protein that is highly similar to the rat Grp78-binding protein (GBP). Alternatively spliced
transcript variants encoding different isoforms have been described. (provided by RefSeq, Jul 2008)

GeneCards Summary for TMEM132A Gene:
TMEM132A (transmembrane protein 132A) is a protein-coding gene. An important paralog of this gene is TMEM132D.

UniProtKB/Swiss-Prot: T132A_HUMAN, Q24JP5
Function: May play a role in embryonic and postnatal development of the brain. Increased resistance to cell death
induced by serum starvation in cultured cells. Regulates cAMP-induced GFAP gene expression via STAT3
phosphorylation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM132A gene promoter:
         CREB   deltaCREB   Olf-1   HNF-4alpha2   AP-4   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM132A promoter sequence
   Search Chromatin IP Primers for TMEM132A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM132A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.2   Ensembl cytogenetic band:  11q12.2   HGNC cytogenetic band: 11q12.2

TMEM132A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM132A gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P060691:  view genomic region     (about GC identifiers)

Start:
60,691,913 bp from pter      End:
60,704,631 bp from pter
Size:
12,719 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: T132A_HUMAN, Q24JP5 (See protein sequence)
Recommended Name: Transmembrane protein 132A precursor  
Size: 1023 amino acids; 110110 Da
Subunit: Interacts with HSPA5/GRP78 (By similarity)
Sequence caution: Sequence=BAB13409.1; Type=Erroneous initiation; Sequence=BAB14613.1; Type=Erroneous initiation;
Secondary accessions: Q69YU7 Q86VZ8 Q86W97 Q9H8K3 Q9HCI9 Q9NWY0
Alternative splicing: 4 isoforms:  Q24JP5-1   Q24JP5-2   Q24JP5-3   Q24JP5-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM132A: NX_Q24JP5

Explore proteomics data for TMEM132A at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn280, Ser800, Thr805
  • Modification sites at PhosphoSitePlus

  • See TMEM132A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_060340.2  NP_821174.1  

    ENSEMBL proteins: 
     ENSP00000442754   ENSP00000405823   ENSP00000005286   ENSP00000439717   ENSP00000437848  
     ENSP00000439716  

    TMEM132A Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for TMEM132A 

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    Search eBioscience for ELISAs for TMEM132A 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026307 TMEM132

    Graphical View of Domain Structure for InterPro Entry Q24JP5

    ProtoNet protein and cluster: Q24JP5

    UniProtKB/Swiss-Prot: T132A_HUMAN, Q24JP5
    Similarity: Belongs to the TMEM132 family


    Find genes that share domains with TMEM132A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: T132A_HUMAN, Q24JP5
    Function: May play a role in embryonic and postnatal development of the brain. Increased resistance to cell death
    induced by serum starvation in cultured cells. Regulates cAMP-induced GFAP gene expression via STAT3
    phosphorylation (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with TMEM132A           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Tmem132a (no phenotypes)

    Find genes that share phenotypes with TMEM132A           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM132A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM132A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM132A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM132A

    miRNA
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    miRTarBase miRNAs that target TMEM132A:
    hsa-mir-26b-5p (MIRT029146), hsa-mir-615-3p (MIRT039799)

    Block miRNA regulation of human, mouse, rat TMEM132A using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate TMEM132A:
    hsa-miR-203 hsa-miR-522 hsa-miR-218-1* hsa-miR-29a hsa-miR-29c hsa-miR-224* hsa-miR-890 hsa-miR-29b
    SwitchGear 3'UTR luciferase reporter plasmidTMEM132A 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TMEM132A

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM132A (NM_178031)
    Sino Biological Human cDNA Clone for TMEM132A
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM132A

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM132A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    T132A_HUMAN, Q24JP5: Golgi apparatus membrane; Single-pass type I membrane protein (By similarity). Endoplasmic
    reticulum membrane; Single-pass type I membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    golgi apparatus5
    plasma membrane3
    extracellular1
    lysosome1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005575cellular_component ND--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM132A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including TMEM132A: 
              Epithelial to Mesenchymal Transition (EMT) in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for TMEM132A

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for TMEM132A (Q24JP53 ENSP000000052864) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSPA5P110213, ENSP000003241734I2D: score=2 STRING: ENSP00000324173
    GSK3BP498413, ENSP000003248064I2D: score=1 STRING: ENSP00000324806
    MEGF10Q96KG73, ENSP000002744734I2D: score=2 STRING: ENSP00000274473
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with TMEM132A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM132A (T132A)

    1 HMDB Compound for TMEM132A    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cyclic AMPCyclic AMP (see all 19)60-92-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM132A gene (2 alternative transcripts): 
    NM_017870.3  NM_178031.2  

    Unigene Cluster for TMEM132A:

    Transmembrane protein 132A
    Hs.118552  [show with all ESTs]
    Unigene Representative Sequence: NM_017870
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000537065 ENST00000544065 ENST00000453848 ENST00000005286(uc001nqi.3 uc001nqj.3)
    ENST00000543732 ENST00000540276 ENST00000537110 ENST00000534983(uc001nqk.3)
    ENST00000544098(uc001nql.1) ENST00000536409 ENST00000539899 ENST00000536928
    ENST00000538090 ENST00000540112 ENST00000535480
    miRNA
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    Block miRNA regulation of human, mouse, rat TMEM132A using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate TMEM132A:
    hsa-miR-203 hsa-miR-522 hsa-miR-218-1* hsa-miR-29a hsa-miR-29c hsa-miR-224* hsa-miR-890 hsa-miR-29b
    SwitchGear 3'UTR luciferase reporter plasmidTMEM132A 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TMEM132A
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM132A (NM_178031)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM132A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM132A
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM132A
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM132A
      QuantiFast Probe-based Assays in human, mouse, rat TMEM132A

    Additional mRNA sequence: 

    AK000546.1 AK023577.1 AL359557.2 BC028106.1 BC032059.1 BC114569.1 

    16 DOTS entries:

    DT.110955  DT.91825116  DT.100695860  DT.100774980  DT.100881895  DT.120716106  DT.100753315  DT.100881892 
    DT.101983069  DT.102837369  DT.40260627  DT.95132088  DT.100802774  DT.92008579  DT.92425645  DT.95191935 

    Selected AceView cDNA sequences (see all 265):

    AW238793 CA397294 CD671423 BX374511 BM722879 AL359557 AW014505 NM_017870 
    BE856556 AK023577 AI582247 BM557905 BE839497 BM927994 AI582351 BU079170 
    BQ637400 BM991527 BU078886 BM126439 AW079423 BM679069 AI923012 BI822680 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM132A (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c ^ 13a ·
    SP1:                    -     -     -     -     -     -     -                                                     -                 -     -                     
    SP2:                    -     -     -     -     -     -     -                                                     -                 -     -                     
    SP3:                                                                                                                                                            
    SP4:              -     -     -     -     -     -     -     -                                                                                                   
    SP5:                                                                                                                                                            

    ExUns: 13b · 13c ^ 14
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for TMEM132A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM132A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCTTATTT
    TMEM132A Expression
    About this image


    TMEM132A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Smooth Muscle (Muscoskeletal System)
    TMEM132A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM132A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.118552
        Pathway & Disease-focused RT2 Profiler PCR Array including TMEM132A: 
              Epithelial to Mesenchymal Transition (EMT) in human mouse rat

    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM132A
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    QuantiFast Probe-based Assays in human, mouse, rat TMEM132A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM132A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TMEM132A gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem132a1 , 5 transmembrane protein 132A1, 5 83.68(n)1
    86.82(a)1
      19 (7.26 cM)5
    981701  NM_133804.21  NP_598565.21 
     108578225 
    chicken
    (Gallus gallus)
    Aves --
    --
    Uncharacterized protein
    67(a)
    56(a)
    1 ↔ many
    1 ↔ many
    AADN03014841.1(2-1115)
    AADN03025400.1(1-1166)
    lizard
    (Anolis carolinensis)
    Reptilia TMEM132A6
    transmembrane protein 132A
    50(a)
    1 ↔ 1
    GL343235.1(410221-436627)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem132a1 transmembrane protein 132A 46.93(n)
    37.75(a)
      100491977  XM_002942114.2  XP_002942160.1 
    zebrafish
    (Danio rerio)
    Actinopterygii TMEM132A6
    transmembrane protein 132A
    23(a)
    1 ↔ 1
    1(45441383-45452806) ENSDARG00000089439
    fruit fly
    (Drosophila melanogaster)
    Insecta CG144466
    --
    18(a)
    1 → many
    X(6119680-6127199)
    worm
    (Caenorhabditis elegans)
    Secernentea Y71H2AM.106
    Protein Y71H2AM.10 (Y71H2AM.10) mRNA, complete cds...
    16(a)
    1 → many
    III(2707737-2716277) WBGene00022175


    ENSEMBL Gene Tree for TMEM132A (if available)
    TreeFam Gene Tree for TMEM132A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM132A gene
    TMEM132D2  TMEM132C2  TMEM132B2  TMEM132E2  
    3 SIMAP similar genes for TMEM132A using alignment to 5 protein entries:     T132A_HUMAN (see all proteins):
    TMEM132C    TMEM132B    TMEM132D

    Find genes that share paralogs with TMEM132A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM132A (see all 351)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1391462651,2
    --60691460(+) TAAGCA/GCTGCA 2 -- us2k10--------
    rs734930471,2
    C,F--60691473(+) ACGCTG/CCCCAG 2 -- us2k11Minor allele frequency- C:0.16WA 118
    rs734930501,2
    C,F--60691652(+) TCTGAC/TTCAGG 2 -- us2k12Minor allele frequency- T:0.17WA 120
    rs1495893591,2
    --60691688(+) CTTGT-/GGGGGG 2 -- us2k10--------
    rs1117421791,2
    C,F--60691694(+) GGGGGT/GGGGTG 2 -- us2k12Minor allele frequency- G:0.17WA 120
    rs1499422121,2
    --60691841(+) CGCCTA/GAGCGC 2 -- us2k10--------
    rs1133404701,2
    F--60691985(+) GGCGGT/CGGCGG 2 -- ut511Minor allele frequency- C:0.00CSA 1
    rs1114986951,2
    C--60692062(+) ACTGGG/TGCCAC 2 -- ut511Minor allele frequency- T:0.50WA 2
    rs1412743001,2
    --60692491(+) CAGCCA/CGGGCA 2 -- int10--------
    rs1913511271,2
    --60692537(+) GTCATC/TCCCAC 2 -- int10--------

    HapMap Linkage Disequilibrium report for TMEM132A (60691913 - 60704631 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TMEM132A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv897601CNV Loss21882294
    nsv897599CNV Loss21882294
    nsv897600CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM132A gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with TMEM132A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Cloning and characterization of a novel GRP78-binding protein in the rat brain. (PubMed id 12514190)1, 3 Oh-hashi K....Tanaka M. (J. Biol. Chem. 2003)
    4. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (EMBO J. 2013)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. GRP78-binding protein regulates cAMP-induced glial fibrillary acidic protein expression in rat C6 glioblastoma cells. (PubMed id 16806201)1 Oh-hashi K....Kiuchi K. (FEBS Lett. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54972 HGNC: 31092 AceView: HSPA5BP1 Ensembl:ENSG00000006118 euGenes: HUgn54972
    ECgene: TMEM132A H-InvDB: TMEM132A

    (According to HUGE)
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    HUGE: KIAA1583

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TMEM132A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM132A gene:
    Search GeneIP for patents involving TMEM132A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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