Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms of Use
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
GeneCards Plus
- Premium Tools
  
  Learn more

Set Analyses:

VarElect

Advanced Search

TMEM129 Gene

protein-coding GIFtS: 46
GCID: GC04M001717

Transmembrane Protein 129

See related disease
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 129¹ ²
D4S2561E²

External Ids:	HGNC: 25137¹	Entrez Gene: 92305²	Ensembl: ENSG00000168936⁷	UniProtKB: A0AVI4³

Export aliases for TMEM129 gene to outside databases

Previous GC identifers: GC04M001687 GC04M001660

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM129 Gene:

TMEM129 (transmembrane protein 129) is a protein-coding gene. Diseases associated with TMEM129 include malaria.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus

RefSeq DNA sequence:

NC_000004.12 NT_006051.19 NC_018915.2

Regulatory elements:

Regulatory transcription factor binding sites in the TMEM129 gene promoter:
GR p53 GR-beta GR-alpha Nkx2-5 NF-E2 NF-E2 p45
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMEM129 promoter sequence

Search Chromatin IP Primers for TMEM129

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM129

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3 Ensembl cytogenetic band: 4p16.3 HGNC cytogenetic band: 4p16.3

TMEM129 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM129 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M001717: view genomic region (about GC identifiers)

Start:	1,717,679 bp from pter	End:	1,723,085 bp from pter
Size:	5,407 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TM129_HUMAN, A0AVI4 (See protein sequence)

Recommended Name: Transmembrane protein 129 precursor

Size: 362 amino acids; 40464 Da

Secondary accessions: A6NH49 A6NI98 D3DVP8

Alternative splicing: 2 isoforms: A0AVI4-1 A0AVI4-2

Explore the universe of human proteins at neXtProt for TMEM129: NX_A0AVI4

Explore proteomics data for TMEM129 at MOPED

Post-translational modifications:

Glycosylation² at Asn229

Modification sites at PhosphoSitePlus

See TMEM129 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_001120738.1 NP_612394.1

ENSEMBL proteins:

ENSP00000305243 ENSP00000372394 ENSP00000417412 ENSP00000417259 ENSP00000441812

TMEM129 Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for TMEM129 OriGene Custom MassSpec OriGene Custom Protein Services for TMEM129
	GenScript Custom Purified and Recombinant Proteins Services for TMEM129
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for TMEM129

TMEM129 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for TMEM129
	Novus Biologicals TMEM129 Antibody
	Search for Antibodies for TMEM129 at Abcam
	Cloud-Clone Corp. Antibodies for TMEM129
	Search ThermoFisher Antibodies for TMEM129
	Search LSBio for Antibodies for TMEM129

TMEM129 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for TMEM129
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for TMEM129
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for TMEM129 Cloud-Clone Corp. CLIAs for TMEM129

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

1 InterPro protein domain:

IPR018801 Tmpp129

Graphical View of Domain Structure for InterPro Entry A0AVI4

ProtoNet protein and cluster: A0AVI4

UniProtKB/Swiss-Prot: TM129_HUMAN, A0AVI4

Similarity: Belongs to the TMEM129 family

TMEM129 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

TMEM129 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for TMEM129:

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM129

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM129

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM129

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM129

miRNA Products:		miRTarBase miRNAs that target TMEM129: hsa-mir-324-5p (MIRT043184)

		Block miRNA regulation of human, mouse, rat TMEM129 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate TMEM129 (see all 11):
		hsa-miR-3163 hsa-miR-3690 hsa-miR-3910 hsa-miR-378b hsa-miR-422a hsa-miR-124 hsa-miR-506 hsa-miR-378c

		SwitchGear 3'UTR luciferase reporter plasmid: TMEM129 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for TMEM129
		Predesigned siRNA for gene silencing in human, mouse, rat TMEM129

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for TMEM129

Clone Products:		OriGene clones in human, mouse for TMEM129 (see all 12) OriGene ORF clones in mouse, rat for TMEM129 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): TMEM129 (NM_001127266)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM129
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM129

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TMEM129
		Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM129

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM129

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot

TM129_HUMAN, A0AVI4: Membrane; Multi-pass membrane protein (Potential)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
plasma membrane	3
extracellular	2
lysosome	1

About this image

Gene Ontology (GO): 2 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--
GO:0016021	integral component of membrane	IEA	--

TMEM129 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for TMEM129
Interactions:

Search GeneGlobe Interaction Network for TMEM129

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for TMEM129 (ENSP00000372394⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

Gene Ontology (GO): 1 biological process term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

TMEM129 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for TMEM129 (TM129)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for TMEM129 gene (2 alternative transcripts):

NM_001127266.1 NM_138385.3

Unigene Cluster for TMEM129:

Transmembrane protein 129

Hs.518562 [show with all ESTs]

Unigene Representative Sequence: NM_001127266

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000303277(uc003gdm.3) ENST00000382936(uc010iby.3 uc003gdn.3)

ENST00000460722 ENST00000476253 ENST00000480360 ENST00000536901

miRNA Products:		Block miRNA regulation of human, mouse, rat TMEM129 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate TMEM129 (see all 11):
		hsa-miR-3163 hsa-miR-3690 hsa-miR-3910 hsa-miR-378b hsa-miR-422a hsa-miR-124 hsa-miR-506 hsa-miR-378c

		SwitchGear 3'UTR luciferase reporter plasmid: TMEM129 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for TMEM129
		Predesigned siRNA for gene silencing in human, mouse, rat TMEM129

Clone Products:		OriGene clones in human, mouse for TMEM129 (see all 12) OriGene ORF clones in mouse, rat for TMEM129 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): TMEM129 (NM_001127266)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM129
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM129

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for TMEM129
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat TMEM129
		QuantiTect SYBR Green Assays in human, mouse, rat TMEM129
		QuantiFast Probe-based Assays in human, mouse, rat TMEM129

Additional mRNA sequence:

AK098466.1 AK303880.1 AK310320.1 BC009331.2 BC018921.2 BC126370.1

13 DOTS entries:

DT.451775 DT.100755368 DT.100755370 DT.121216962 DT.99970945 DT.100755366 DT.121217001 DT.121216979

DT.92432167 DT.95082332 DT.95129749 DT.95129750 DT.97844837

Selected AceView cDNA sequences (see all 206):

BC009331 BM977729 AI927198 AI393916 AI240436 BQ447161 CR596458 AI573144

BQ675936 CA488731 AI332525 AI474764 AA911788 CF127642 AI762150 AI800358

BM671734 F04500 BC018921 CA311600 BI820666 NM_138385 BU738417 D55809

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM129 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6a	·	6b	·	6c	^	7a	·	7b	·	7c	·	7d
SP1:							-		-						-		-
SP2:
SP3:							-		-						-		-		-
SP4:															-
SP5:

ECgene alternative splicing isoforms for TMEM129

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

TMEM129 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GCCGGGAGCC

About this image

TMEM129 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

TMEM129 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.518562

Custom PCR Arrays for TMEM129

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for TMEM129
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat TMEM129
		QuantiTect SYBR Green Assays in human, mouse, rat TMEM129
		QuantiFast Probe-based Assays in human, mouse, rat TMEM129

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM129

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of animals.

Orthologs for TMEM129 gene from Selected species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Details
mouse (Mus musculus)	Mammalia	Tmem129^{1 , 5}	transmembrane protein 129^{1, 5}	84.35(n)¹ 89.23(a)¹	5 (17.83 cM)⁵ 68366¹ NM_026698.2¹ NP_080974.2¹ 33653216⁵
chicken (Gallus gallus)	Aves	TMEM129¹	transmembrane protein 129	73.2(n) 75.41(a)	422900 NM_001031168.1 NP_001026339.1
tropical clawed frog (Xenopus tropicalis)	Amphibia	tmem129¹	transmembrane protein 129	72.65(n) 74.86(a)	548871 NM_001016117.3 NP_001016117.2
zebrafish (Danio rerio)	Actinopterygii	wufc17d07²	Danio rerio cDNA clone MGC63798 IMAGE3815098, complete more	76.47(n)	BC058876.1
fruit fly (Drosophila melanogaster)	Insecta	CG14646¹	CG14646	49.2(n) 34.08(a)	40555 NM_141205.3 NP_649462.1
worm (Caenorhabditis elegans)	Secernentea	C34F6.7¹	C34F6.7	39.49(n) 27.69(a)	181310 NM_077473.6 NP_509874.1

ENSEMBL Gene Tree for TMEM129 (if available)
TreeFam Gene Tree for TMEM129 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

TryGeneCards Plus

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

SNP ID	Valid	Clinical significance	Chr 4 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs145294949^1,2	C	--	1717745(+)	`AAAAC-/TAAG TAACT`	2	--	ut3¹		0	--	--	--	--
rs798752^1,2,4		--	--	see VAR_032803	2		mis⁴		0	--	--	--	--
rs374625535^1,2	--	--	1717748(+)	`ACTAA-/GTAA CTTAT`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TMEM129 (1717679 - 1723085 bp)

Structural Variations
Database of Genomic Variants (DGV) Selected variations for TMEM129 (see all 15): About this table

Variant ID	Type	Subtype	PubMed ID
esv2726832	CNV	Deletion	23290073
nsv508989	CNV	Insertion	20534489
dgv5416n71	CNV	Loss	21882294
nsv878347	CNV	Loss	21882294
nsv292653	CNV	Loss	16902084
nsv822437	CNV	Loss	20364138
nsv470000	CNV	Loss	18288195
nsv878328	CNV	Loss	21882294
nsv878393	CNV	Loss	21882294
dgv5408n71	CNV	Loss	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing TMEM129

DNA2.0 Custom Variant and Variant Library Synthesis for TMEM129

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus

1 disease for TMEM129: About MalaCards

malaria

TMEM129 for disorders About GeneDecksing

Genetic Association Database (GAD): TMEM129
Human Genome Epidemiology (HuGE) Navigator: TMEM129 (1 document)

Export disorders for TMEM129 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for TMEM129 gene integrated from 10 sources:
(articles sorted by number of sources associating them with TMEM129)

Utopia: connect your pdf to the dynamic
world of online information

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (Mol. Med. 2010)
Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (Mol. Cell 2011)
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. (PubMed id 20348956)¹ Kiemeney L.A....Stefansson K. (Nat. Genet. 2010)
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. (PubMed id 20972438)¹ Rothman N....Chanock S.J. (Nat. Genet. 2010)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)² Hillier L.W.... Wilson R.K. (Nature 2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S.... Malek J. (Genome Res. 2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus

Entrez Gene: 92305	HGNC: 25137	AceView: LOC92305	Ensembl:ENSG00000168936	euGenes: HUgn92305
ECgene: TMEM129	H-InvDB: TMEM129

(According to HUGE)
About This Section

TryGeneCards Plus

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus

Name	Description
PharmGKB entry for TMEM129	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TMEM129 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

TryGeneCards Plus

Patent Information for TMEM129 gene:
Search GeneIP for patents involving TMEM129

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus


	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Enzyme Activity Assays/Reagents
	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for TMEM129
	Browse OriGene qPCR primer pairs and template standards		OriGene Protein Over-expression Lysate for TMEM129
	OriGene Custom Mass Spec		OriGene clones in human, mouse for TMEM129
	OriGene qSTAR qPCR primer pairs in human, mouse for TMEM129		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for TMEM129		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for TMEM129		OriGene Custom Protein Services for TMEM129

	Block miRNA regulation of human, mouse, rat TMEM129 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing TMEM129
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM129		Predesigned siRNA for gene silencing in human, mouse, rat TMEM129
	QuantiFast Probe-based Assays in human, mouse, rat TMEM129		QuantiTect SYBR Green Assays in human, mouse, rat TMEM129
	Custom PCR Arrays for TMEM129		Search Chromatin IP Primers for TMEM129
	Pre-validated RT² qPCR Primer Assay in human, mouse, rat TMEM129		Search GeneGlobe Interaction Network for TMEM129
	Regulatory tfbs in TMEM129 promoter

	GenScript Custom Purified and Recombinant Proteins Services for TMEM129		GenScript cDNA clones with any tag delivered in your preferred vector for TMEM129
	GenScript Custom Assay Services for TMEM129		GenScript Custom overexpressing Cell Line Services for TMEM129
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

Search for Antibodies & Assays

Search Tocris compounds for TMEM129 (TM129)

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	TMEM129 antibodies

	Search for Antibodies for TMEM129 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for TMEM129
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for TMEM129
	Antibodies for TMEM129
	ELISAs for TMEM129
	CLIAs for TMEM129

Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM129

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM129

	SwitchGear 3'UTR luciferase reporter plasmids for TMEM129
	SwitchGear Promoter luciferase reporter plasmids for TMEM129

Search ThermoFisher Antibodies for TMEM129

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM129

	inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM129
	inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM129

Search LSBio for Antibodies for TMEM129

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

Browse compounds at ApexBio

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category			(GIFtS: )
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes TMEM129 gene at Home site.

Version: 3.12.136 22 July 2014
hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4

GeneCards Plus

Advanced Search

Export list of displayed genes

TMEM129 Gene

Transmembrane Protein 129

Aliases
for TMEM129 gene

Summaries
for TMEM129 gene

Genomic Views
for TMEM129 gene

Proteins
for TMEM129 gene

TMEM129 Human Recombinant Protein Products:

TMEM129 Antibody Products:

TMEM129 Assay Products:

Domains /
Families
for TMEM129 gene

Function
for TMEM129 gene

Localization
for TMEM129 gene

Pathways & Interactions
for TMEM129 gene

Drugs & Compounds
for TMEM129 gene

Transcripts
for TMEM129 gene

Expression
for TMEM129 gene

Orthologs
for TMEM129 gene

Paralogs
for TMEM129 gene

Genomic Variants
for TMEM129 gene

Disorders / Diseases
for TMEM129 gene

Publications
for TMEM129 gene

External Searches for TMEM129 gene

Genome Databases showing TMEM129 gene

Other Databases showing TMEM129 gene

Specialized Databases showing TMEM129 gene

Intellectual Property
for TMEM129 gene

Products
for TMEM129 gene

View Random Gene

GeneCards Plus

Advanced Search

Export list of displayed genes

TMEM129 Gene

Transmembrane Protein 129

Aliasesfor TMEM129 gene

Summariesfor TMEM129 gene

Genomic Viewsfor TMEM129 gene

Proteinsfor TMEM129 gene

TMEM129 Human Recombinant Protein Products:

TMEM129 Antibody Products:

TMEM129 Assay Products:

Domains /Familiesfor TMEM129 gene

Functionfor TMEM129 gene

Localizationfor TMEM129 gene

Pathways & Interactionsfor TMEM129 gene

Drugs & Compoundsfor TMEM129 gene

Transcriptsfor TMEM129 gene

Expression for TMEM129 gene

Orthologsfor TMEM129 gene

Paralogsfor TMEM129 gene

Genomic Variantsfor TMEM129 gene

Disorders / Diseasesfor TMEM129 gene

Publicationsfor TMEM129 gene

External Searches for TMEM129 gene

Genome Databases showing TMEM129 gene

Other Databases showing TMEM129 gene

Specialized Databases showing TMEM129 gene

Intellectual Propertyfor TMEM129 gene

Productsfor TMEM129 gene

View Random Gene

Aliases
for TMEM129 gene

Summaries
for TMEM129 gene

Genomic Views
for TMEM129 gene

Proteins
for TMEM129 gene

Domains /
Families
for TMEM129 gene

Function
for TMEM129 gene

Localization
for TMEM129 gene

Pathways & Interactions
for TMEM129 gene

Drugs & Compounds
for TMEM129 gene

Transcripts
for TMEM129 gene

Expression
for TMEM129 gene

Orthologs
for TMEM129 gene

Paralogs
for TMEM129 gene

Genomic Variants
for TMEM129 gene

Disorders / Diseases
for TMEM129 gene

Publications
for TMEM129 gene

Intellectual Property
for TMEM129 gene

Products
for TMEM129 gene