TMEM128 Gene
protein-coding GIFtS: 37
GCID: GC04M004237
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|
transmembrane protein 128
| |
Aliases
for TMEM128 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transmembrane Protein 1281 2 | | MGC131591 |
Export aliases for TMEM128 gene to outside databasesPrevious GC identifers: GC04M004288 GC04M004172 |
Summaries
for TMEM128 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TMEM128 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_006051.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TMEM128 gene promoter:
HOXA9 HOXA9B YY1 Evi-1 POU2F1 POU2F1a Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TMEM128
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM128 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p16.3 Ensembl cytogenetic band: 4p16.3 HGNC cytogenetic band: 4p16.3TMEM128 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M004237: view genomic region
(about GC identifiers)
Start:
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4,237,269 bp from pter |
End:
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4,249,950 bp from pter |
Size:
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12,682 bases |
Orientation:
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minus strand |
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Proteins
for TMEM128 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TM128_HUMAN, Q5BJH2 (See
protein sequence)Recommended Name: Transmembrane protein 128 Size: 165 amino acids; 18822 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: B4DHS7 D3DVS3 Q5H9U6 Q96I94Alternative splicing: 2 isoforms: Q5BJH2-1 Q5BJH2-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TMEM128: NX_Q5BJH2
TMEM128 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_116316.1
ENSEMBL proteins: ENSP00000254742 ENSP00000372201 ENSP00000442300 ENSP00000439174
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- | | GO:0016021 | integral to membrane |
IEA | -- |
TMEM128 for ontologies About GeneDecksing
TMEM128 Antibody Products:
Assay Products for TMEM128: |
Protein
Domains /
Families
for TMEM128 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5BJH2 |
Function
for TMEM128 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM128 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM128
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TMEM128 (NM_032927) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM128 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM128 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM128 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
TMEM128 for ontologies About GeneDecksing
|
Pathways & Interactions
for TMEM128 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM128
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
TMEM128 for ontologies About GeneDecksing
|
Drugs & Compounds
for TMEM128 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TMEM128
Search CenterWatch for drugs/clinical trials and news about TMEM128 / TM128
|
Transcripts
for TMEM128 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TMEM128 gene: NM_032927.2 Unigene Cluster for TMEM128: Transmembrane protein 128 Hs.12845 [show with all ESTs]Unigene Representative Sequence: CR9336114 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000254742(uc003ghq.1 uc003ghr.1 uc003ghs.3) ENST00000382753
ENST00000538516(uc011bvv.1 uc011bvw.1) ENST00000540397
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM128 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM128
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TMEM128 (NM_032927) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM128 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM128 |
Additional cDNA sequence: AK001453.1 AK054701.1 AK295248.1 AK296007.1 BC007729.2 BC091482.1 CR933611.1 7 DOTS entries: DT.216224 DT.100751381 DT.92429183 DT.95202682 DT.95325144 DT.121242973 DT.121242966 24/145 AceView cDNA sequences (see all 145): F09519 BM453946 AA555070 AI962753 BX416075 AL519982 AK054701 CA414019 D62868 AW264527 BX499927 AA279404 BI821616 CR600962 BF792179 AA506271 BQ896897 CR621378 CA445436 BQ774244 AI681856 CA943313 CR606526 AA279915
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM128 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for TMEM128
|
Expression
for TMEM128 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMEM128 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCCTTTAAC
About this image
See TMEM128 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM128
SOURCE GeneReport for Unigene cluster: Hs.12845
SABiosciences Custom PCR Arrays for TMEM128
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM128
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM128 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM128 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM128 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM128 |
Orthologs
for TMEM128 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TMEM128 gene from 5/14 species (see all 14) About this table
ENSEMBL Gene Tree for TMEM128 (if available)
TreeFam Gene Tree for TMEM128 (if available) |
Paralogs
for TMEM128 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TMEM128 gene
TMEM128 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for TMEM128
PGOHUM00000234311 PGOHUM00000240765 PGOHUM00000245973
|
Genomic Variants
for TMEM128 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for TMEM128
5 CNVs: 91893 80156 91892 3477 80155 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM128 |
|
Disorders
/ Diseases
for TMEM128 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TMEM128 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMEM128 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TMEM128) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TMEM128 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TMEM128 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMEM128 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMEM128 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TMEM128 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TMEM128 gene:
Search GeneIP for patents involving TMEM128
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TMEM128 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TMEM128 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM128 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM128 | | | OriGene Protein Over-expression Lysate for TMEM128 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TMEM128 | | OriGene 3'-UTR Clone for TMEM128 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM128 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM128 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TMEM128 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMEM128 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM128 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM128 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM128 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM128 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM128 |
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 |  |  |  | |
| | | | Search Tocris compounds for TMEM128 |
| |  |  |  |  | | | | |
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 | | | TMEM128 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM128 |
|  |  |  | | | | Search ThermoFisher Antibodies for TMEM128 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM128 |
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