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Aliases for TMEM125 Gene

Aliases for TMEM125 Gene

  • Transmembrane Protein 125 2 3

External Ids for TMEM125 Gene

Summaries for TMEM125 Gene

GeneCards Summary for TMEM125 Gene

TMEM125 (Transmembrane Protein 125) is a Protein Coding gene. Diseases associated with TMEM125 include colorectal cancer.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM125 Gene

Genomics for TMEM125 Gene

Genomic Location for TMEM125 Gene

43,269,994 bp from pter
43,274,002 bp from pter
4,009 bases
Plus strand

Genomic View for TMEM125 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM125 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM125 Gene

Regulatory Elements for TMEM125 Gene

Proteins for TMEM125 Gene

  • Protein details for TMEM125 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 125
    Protein Accession:
    Secondary Accessions:
    • D3DPX1

    Protein attributes for TMEM125 Gene

    219 amino acids
    Molecular mass:
    22172 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM125 Gene

Proteomics data for TMEM125 Gene at MOPED

Post-translational modifications for TMEM125 Gene

No Post-translational modifications

Other Protein References for TMEM125 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM125 Gene

Domains for TMEM125 Gene

Protein Domains for TMEM125 Gene

genes like me logo Genes that share domains with TMEM125: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM125 Gene

Function for TMEM125 Gene

Gene Ontology (GO) - Molecular Function for TMEM125 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TMEM125: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM125 Gene

Localization for TMEM125 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM125 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM125 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM125: view

Pathways for TMEM125 Gene

SuperPathways for TMEM125 Gene

No Data Available

Interacting Proteins for TMEM125 Gene

Gene Ontology (GO) - Biological Process for TMEM125 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TMEM125: view

No data available for Pathways by source for TMEM125 Gene

Transcripts for TMEM125 Gene

Unigene Clusters for TMEM125 Gene

Transmembrane protein 125:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM125 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b
SP1: -
SP3: -

Relevant External Links for TMEM125 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM125 Gene

mRNA expression in normal human tissues for TMEM125 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM125 Gene

This gene is overexpressed in Pancreas (7.3), Lung (5.6), and Brain - Spinal cord (cervical c-1) (4.6).

SOURCE GeneReport for Unigene cluster for TMEM125 Gene Hs.104476

genes like me logo Genes that share expressions with TMEM125: view

Orthologs for TMEM125 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM125 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TMEM125 36
  • 100 (n)
  • 100 (a)
TMEM125 37
  • 100 (a)
(Bos Taurus)
Mammalia TMEM125 36
  • 86.76 (n)
  • 88.58 (a)
TMEM125 37
  • 89 (a)
(Canis familiaris)
Mammalia TMEM125 36
  • 86.05 (n)
  • 88.84 (a)
TMEM125 37
  • 89 (a)
(Mus musculus)
Mammalia Tmem125 36
  • 84.04 (n)
  • 87.32 (a)
Tmem125 16
Tmem125 37
  • 86 (a)
(Monodelphis domestica)
Mammalia TMEM125 37
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM125 37
  • 67 (a)
(Gallus gallus)
Aves TMEM125 36
  • 62.93 (n)
  • 58.16 (a)
(Anolis carolinensis)
Reptilia TMEM125 37
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem125 36
  • 52.45 (n)
  • 45.59 (a)
(Danio rerio)
Actinopterygii CABZ01069519.1 37
  • 41 (a)
tmem125b 37
  • 37 (a)
Species with no ortholog for TMEM125:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM125 Gene

Gene Tree for TMEM125 (if available)
Gene Tree for TMEM125 (if available)

Paralogs for TMEM125 Gene

No data available for Paralogs for TMEM125 Gene

Variants for TMEM125 Gene

Sequence variations from dbSNP and Humsavar for TMEM125 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1212462 -- 43,268,704(+) CGCCC(C/G)Cagac upstream-variant-2KB
rs1334051 -- 43,273,396(-) AAGGA(C/T)GGCTC utr-variant-3-prime
rs3053220 -- 43,270,024(-) AAATG(A/C/T)GCCCC utr-variant-5-prime, upstream-variant-2KB
rs3795726 -- 43,272,301(+) CAGCC(A/G)GGATG utr-variant-5-prime
rs6674706 -- 43,271,851(+) GGCAG(A/G/T)GATGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM125 Gene

Variant ID Type Subtype PubMed ID
nsv829693 CNV Loss 17160897
nsv508009 CNV Loss 20534489

Relevant External Links for TMEM125 Gene

HapMap Linkage Disequilibrium report

Disorders for TMEM125 Gene

(1) MalaCards Diseases for TMEM125 Gene

Search for TMEM125 Gene in MalaCards »
genes like me logo Genes that share disorders with TMEM125: view

No data available for UniProtKB/Swiss-Prot for TMEM125 Gene

Publications for TMEM125 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4
  3. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMEM125 Gene

Sources for TMEM125 Gene

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