Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM120A Gene

protein-coding   GIFtS: 49
GCID: GC07M075618

Transmembrane Protein 120A

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 120A1 2
Transmembrane Protein Induced By Tumor Necrosis Factor Alpha2 3
TMPIT2 3
NET292

External Ids:    HGNC: 216971   Entrez Gene: 838622   Ensembl: ENSG000001890777   UniProtKB: Q9BXJ83   

Export aliases for TMEM120A gene to outside databases

Previous GC identifers: GC07M075455 GC07M070702


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM120A Gene:
TMEM120A (transmembrane protein 120A) is a protein-coding gene. Diseases associated with TMEM120A include malaria. An important paralog of this gene is TMEM120B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000007.14  NC_018918.2  NT_007933.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM120A gene promoter:
         Max1   Pax-5   Egr-1   FOXD3   LCR-F1   c-Ets-1   c-Myb   ZIC2/Zic2   GCNF-2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM120A promoter sequence
   Search Chromatin IP Primers for TMEM120A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM120A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q11.23   Ensembl cytogenetic band:  7q11.23   HGNC cytogenetic band: 7q11.23

TMEM120A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM120A gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M075618:  view genomic region     (about GC identifiers)

Start:
75,616,155 bp from pter      End:
75,623,992 bp from pter
Size:
7,838 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 74,949,219-74,957,056     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: T120A_HUMAN, Q9BXJ8 (See protein sequence)
Recommended Name: Transmembrane protein 120A  
Size: 343 amino acids; 40610 Da
Secondary accessions: Q86TE9 Q8N6P1
Alternative splicing: 2 isoforms:  Q9BXJ8-1   Q9BXJ8-2   

Explore the universe of human proteins at neXtProt for TMEM120A: NX_Q9BXJ8

Explore proteomics data for TMEM120A at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn117
  • Modification sites at PhosphoSitePlus

  • See TMEM120A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_114131.1  
    ENSEMBL proteins: 
     ENSP00000473983  

    TMEM120A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TMEM120A
    OriGene Protein Over-expression Lysate for TMEM120A
    OriGene MassSpec for TMEM120A
    OriGene Custom Protein Services for TMEM120A
    GenScript Custom Purified and Recombinant Proteins Services for TMEM120A
    Novus Biologicals TMEM120A Protein
    Novus Biologicals TMEM120A Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM120A

    TMEM120A Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of TMEM120A
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM120A
    Novus Biologicals TMEM120A Antibodies
    Abcam antibodies for TMEM120A
    Cloud-Clone Corp. Antibodies for TMEM120A
    Search ThermoFisher Antibodies for TMEM120A
    Search LSBio for Antibodies for TMEM120A

    TMEM120A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM120A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM120A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM120A
    Cloud-Clone Corp. CLIAs for TMEM120A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR012926 TMPIT

    Graphical View of Domain Structure for InterPro Entry Q9BXJ8

    ProtoNet protein and cluster: Q9BXJ8

    1 Blocks protein domain: IPB012926 TMPIT-like

    UniProtKB/Swiss-Prot: T120A_HUMAN, Q9BXJ8
    Similarity: Belongs to the TMEM120 family


    TMEM120A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    TMEM120A for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM120A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM120A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM120A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM120A

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM120A:
    hsa-mir-335-5p (MIRT019165)

    Block miRNA regulation of human, mouse, rat TMEM120A using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate TMEM120A:
    hsa-miR-148b* hsa-miR-561 hsa-miR-3918
    SwitchGear 3'UTR luciferase reporter plasmidTMEM120A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM120A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM120A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM120A

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM120A (see all 6)
    OriGene ORF clones in mouse, rat for TMEM120A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM120A (NM_031925)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM120A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM120A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM120A
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM120A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM120A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    T120A_HUMAN, Q9BXJ8: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane2
    cytosol1
    endoplasmic reticulum1
    extracellular1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0016021integral component of membrane IEA--

    TMEM120A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM120A
    Interactions:

        Search GeneGlobe Interaction Network for TMEM120A

    1 Interacting protein for TMEM120A (Q9BXJ82, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GOT1P171742, 3MINT-64803 I2D: score=4 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    TMEM120A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM120A (T120A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM120A gene: 
    NM_031925.2  

    Unigene Cluster for TMEM120A:

    Transmembrane protein 120A
    Hs.488835  [show with all ESTs]
    Unigene Representative Sequence: BM805119
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000338761(uc003ued.3 uc003uec.2) ENST00000417509(uc003ueb.1)
    ENST00000484946 ENST00000490656 ENST00000439537 ENST00000493251 ENST00000460127
    ENST00000440632(uc022agl.1) ENST00000480899 ENST00000493111 ENST00000465989
    ENST00000431867 ENST00000465494 ENST00000480538 ENST00000485200 ENST00000486865
    ENST00000485581
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM120A using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate TMEM120A:
    hsa-miR-148b* hsa-miR-561 hsa-miR-3918
    SwitchGear 3'UTR luciferase reporter plasmidTMEM120A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM120A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM120A
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM120A (see all 6)
    OriGene ORF clones in mouse, rat for TMEM120A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM120A (NM_031925)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM120A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM120A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM120A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM120A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM120A
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM120A
      QuantiFast Probe-based Assays in human, mouse, rat TMEM120A

    Additional mRNA sequence: 

    AF327923.1 BC029487.1 BC040694.1 BC051850.1 

    16 DOTS entries:

    DT.100829178  DT.314204  DT.100797407  DT.121058932  DT.100797411  DT.121058854  DT.100036201  DT.75102554 
    DT.100797402  DT.100797405  DT.100797408  DT.100797410  DT.97794490  DT.100708585  DT.102838685  DT.121058913 

    Selected AceView cDNA sequences (see all 367):

    AI028279 AI928433 CB853481 CA431409 AF327923 BM967133 CD105509 T35406 
    AA431177 BG912682 CB528505 AW593087 CR590394 AF169648 CA425110 H17476 
    BQ421226 AA630057 AA782050 CD366475 AF169647 CR611131 AA961038 BM797251 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM120A    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b
    SP1:                                                  -                                                   
    SP2:                                                                                                      
    SP3:                                                  -                                                   
    SP4:                                -                                                                     
    SP5:                                                                          -     -                     


    ECgene alternative splicing isoforms for TMEM120A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM120A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACCTCACTG
    TMEM120A Expression
    About this image


    TMEM120A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Testis (Reproductive System)
    TMEM120A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM120A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.488835
        Custom PCR Arrays for TMEM120A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM120A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM120A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM120A
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM120A
    QuantiFast Probe-based Assays in human, mouse, rat TMEM120A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM120A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for TMEM120A gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem120a1 , 5 transmembrane protein 120A1, 5 87.76(n)1
    94.75(a)1
      5 (75.38 cM)5
    2152101  NM_172541.21  NP_766129.11 
     1357354855 
    chicken
    (Gallus gallus)
    Aves TMEM120A1 transmembrane protein 120A 79.43(n)
    79.23(a)
      417519  XM_415767.4  XP_415767.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM120A6
    transmembrane protein 120A
    67(a)
    1 ↔ 1
    GL343734.1(117977-131209)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem120a1 transmembrane protein 120A 72.14(n)
    78.42(a)
      548366  NM_001114210.1  NP_001107682.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.143182 Transcribed sequence with weak similarity to protein more 77.03(n)    BI670891.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG327951 CG32795 59.79(n)
    48.62(a)
      31270  NM_001258580.1  NP_001245509.1 
    worm
    (Caenorhabditis elegans)
    Secernentea M01G5.36
    Protein M01G5.3 (M01G5.3) mRNA, complete cds
    38(a)
    1 → many
    III(1508795-1517993) WBGene00019716


    ENSEMBL Gene Tree for TMEM120A (if available)
    TreeFam Gene Tree for TMEM120A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMEM120A gene
    TMEM120B2  
    1 SIMAP similar gene for TMEM120A using alignment to 1 protein entry:     T120A_HUMAN:
    TMEM120B

    TMEM120A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM120A (see all 298)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2021112761,2
    C--75616827(-) GCCTGC/TCTGTC 1 -- int10--------
    rs1114110791,2
    C--75618095(+) CGGGTA/GGGGGG 1 -- int10--------
    rs1120216851,2
    C--75618380(+) GGTTCC/GGGGGG 1 -- int10--------
    rs1864079551,2
    --75618427(+) GGGGGG/TAGGGG 1 -- int10--------
    rs32143341,2
    C--75618822(+) GGGCA-/CCAAGA 1 -- int12Minor allele frequency- C:0.25NA CSA 4
    rs2000933971,2
    --78923925(+) AGAAG-/TACCCA 1 -- int10--------
    rs117678161,2
    C,F,A,H--78923926(+) AGAAGA/TCCCAG 1 -- int13Minor allele frequency- T:0.37NA 124
    rs117664641,2
    C,F,A,H--78923927(+) GAAGAC/ACCAGT 1 -- int14Minor allele frequency- A:0.04NS NA 356
    rs1815535361,2
    C--78923946(+) GAGCCC/TGAAAC 1 -- int10--------
    rs717415661,2
    C--78923966(+) GGACG-/GACA  
            
    GACAG
    1 -- int11Minor allele frequency- GACA:0.00CSA 2

    HapMap Linkage Disequilibrium report for TMEM120A (75616155 - 75623992 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for TMEM120A:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv120n16CNV Deletion17901297
    esv27597CNV Loss19812545
    nsv888386CNV Gain21882294
    nsv528969CNV Gain19592680
    nsv428173CNV Gain18775914
    essv14753CNV CNV17122850
    dgv2103e1CNV Complex17122850
    dgv2104e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing TMEM120A
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM120A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for TMEM120A:    
    About MalaCards
    malaria


    TMEM120A for disorders           About GeneDecksing


    Export disorders for TMEM120A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM120A gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEM120A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    2. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PubMed id 21103663)1 Schaafhausen A....MA1ller C.R. (Thromb. Haemost. 2011)
    3. Identification of the human testis protein phosphatase 1 interactome. (PubMed id 21382349)1 Fardilha M....da Cruz e Silva E.F. (Biochem. Pharmacol. 2011)
    4. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    7. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    8. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 83862 HGNC: 21697 AceView: MK-STYXandTMPIT Ensembl:ENSG00000189077 euGenes: HUgn83862
    ECgene: TMEM120A H-InvDB: TMEM120A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM120A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM120A gene:
    Search GeneIP for patents involving TMEM120A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     Browse Kits and Assays available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of TMEM120A
     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse Small Molecules at EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM120A  
     OriGene qPCR primer pairs and template standards for TMEM120A   OriGene Protein Over-expression Lysate for TMEM120A  
     OriGene MassSpec something-or-other for TMEM120A   OriGene clones in human, mouse for TMEM120A  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM120A   OriGene Purified Protein for TMEM120A  
     OriGene ORF clones in mouse, rat for TMEM120A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM120A   OriGene Custom Protein Services for TMEM120A  

     
     
     Block miRNA regulation of human, mouse, rat TMEM120A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM120A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM120A Predesigned siRNA for gene silencing in human, mouse, rat TMEM120A
     QuantiFast Probe-based Assays in human, mouse, rat TMEM120A QuantiTect SYBR Green Assays in human, mouse, rat TMEM120A
     Custom PCR Arrays for TMEM120A Search Chromatin IP Primers for TMEM120A
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM120A  Search GeneGlobe Interaction Network for TMEM120A
     Regulatory tfbs in TMEM120A promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM120A GenScript cDNA clones with any tag delivered in your preferred vector for TMEM120A
     GenScript Custom Assay Services for TMEM120A GenScript Custom overexpressing Cell Line Services for TMEM120A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM120A (T120A)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM120A antibodies
     TMEM120A proteins
     TMEM120A lysates
     Antibodies for TMEM120A
     See all of Abcam's Antibodies, Kits and Proteins for TMEM120A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM120A
     Antibodies for TMEM120A
     ELISAs for TMEM120A
     CLIAs for TMEM120A



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM120A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM120A
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM120A
     SwitchGear Promoter luciferase reporter plasmids for TMEM120A
     Search ThermoFisher Antibodies for TMEM120A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM120A
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM120A
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM120A
     Search LSBio for Antibodies for TMEM120A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM120A gene at Home site.
    Version: 3.12.162 20 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4