Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM116 Gene

protein-coding   GIFtS: 38
GCID: GC12M112369

Transmembrane Protein 116

  Search for TMEM116
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 1161 2

External Ids:    HGNC: 250841   Entrez Gene: 898942   Ensembl: ENSG000001982707   UniProtKB: Q8NCL83   

Export aliases for TMEM116 gene to outside databases

Previous GC identifers: GC12M110832 GC12M109382


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM116 Gene:
TMEM116 (transmembrane protein 116) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM116 gene promoter:
         AML1a   Pbx1a   GATA-3   POU3F1   MyoD   POU3F2 (N-Oct-5a)   Cdc5   E47   FOXO4   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM116 promoter sequence
   Search Chromatin IP Primers for TMEM116

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM116


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.13   Ensembl cytogenetic band:  12q24.13   HGNC cytogenetic band: 12q24.13

TMEM116 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM116 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M112369:  view genomic region     (about GC identifiers)

Start:
112,369,086 bp from pter      End:
112,451,023 bp from pter
Size:
81,938 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TM116_HUMAN, Q8NCL8 (See protein sequence)
Recommended Name: Transmembrane protein 116  
Size: 245 amino acids; 27464 Da
Secondary accessions: G3V1W7 G5E985 Q6NSH5 Q8IZ66
Alternative splicing: 3 isoforms:  Q8NCL8-1   Q8NCL8-2   Q8NCL8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM116: NX_Q8NCL8

Explore proteomics data for TMEM116 at MOPED


See TMEM116 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts): 
NP_001180382.1  NP_001180460.1  NP_612350.1  

ENSEMBL proteins: 
 ENSP00000450377   ENSP00000347620   ENSP00000448413   ENSP00000447731   ENSP00000449163  
 ENSP00000474027   ENSP00000446516   ENSP00000447425   ENSP00000446491   ENSP00000449774  
 ENSP00000446766   ENSP00000450060   ENSP00000346883   ENSP00000395861  

TMEM116 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for TMEM116
OriGene Custom MassSpec
OriGene Custom Protein Services for TMEM116
GenScript Custom Purified and Recombinant Proteins Services for TMEM116
Novus Biologicals TMEM116 Protein
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for TMEM116

 
Search eBioscience for Proteins for TMEM116 

TMEM116 Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for TMEM116
Novus Biologicals TMEM116 Antibody
Abcam antibodies for TMEM116
Cloud-Clone Corp. Antibodies for TMEM116
Search ThermoFisher Antibodies for TMEM116
LSBio Antibodies in human, mouse, rat for TMEM116

TMEM116 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for TMEM116
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for TMEM116
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for TMEM116
Cloud-Clone Corp. CLIAs for TMEM116
Search eBioscience for ELISAs for TMEM116 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

ProtoNet protein and cluster: Q8NCL8


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
Find genes that share ontologies with TMEM116           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM116
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM116

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM116
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM116

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat TMEM116 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate TMEM116:
hsa-miR-3688-3p
SwitchGear 3'UTR luciferase reporter plasmidTMEM116 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for TMEM116
Predesigned siRNA for gene silencing in human, mouse, rat TMEM116

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for TMEM116

Clone
Products:
     
OriGene clones in human, mouse for TMEM116 (see all 13)
OriGene ORF clones in mouse, rat for TMEM116
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 3): TMEM116 (NM_001193531)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM116
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM116

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for TMEM116
Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM116 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM116


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot
TM116_HUMAN, Q8NCL8: Membrane; Multi-pass membrane protein (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane3
cytoskeleton1
nucleus1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0016021integral component of membrane IEA--

Find genes that share ontologies with TMEM116           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM116
Interactions:

    Search GeneGlobe Interaction Network for TMEM116

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for TMEM116 (ENSP000003468834) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
InteractantInteraction Details
GeneCardExternal ID(s)
HIRAENSP000002632084STRING: ENSP00000263208
PSMC4ENSP000001578124STRING: ENSP00000157812
AASDHENSP000002052144STRING: ENSP00000205214
COPB1ENSP000002499234STRING: ENSP00000249923
KIAA0368ENSP000002593354STRING: ENSP00000259335
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008150biological_process ND--

Find genes that share ontologies with TMEM116           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for TMEM116 (TM116)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for TMEM116 gene (3 alternative transcripts): 
NM_001193453.1  NM_001193531.1  NM_138341.2  

Unigene Cluster for TMEM116:

Transmembrane protein 116
Hs.506815  [show with all ESTs]
Unigene Representative Sequence: AL833501
Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
ENST00000550831 ENST00000355445 ENST00000547878 ENST00000552374 ENST00000549537
ENST00000552801 ENST00000548283(uc001tti.2) ENST00000550800 ENST00000550037
ENST00000551297 ENST00000550020 ENST00000546537 ENST00000549425 ENST00000552839
ENST00000546962 ENST00000550233 ENST00000552800 ENST00000354825(uc001ttd.2 uc001tte.2 uc001ttf.2 uc001ttc.2)

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat TMEM116 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate TMEM116:
hsa-miR-3688-3p
SwitchGear 3'UTR luciferase reporter plasmidTMEM116 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for TMEM116
Predesigned siRNA for gene silencing in human, mouse, rat TMEM116
Clone
Products:
     
OriGene clones in human, mouse for TMEM116 (see all 13)
OriGene ORF clones in mouse, rat for TMEM116
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 3): TMEM116 (NM_001193531)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM116
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM116
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM116
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM116
  QuantiTect SYBR Green Assays in human, mouse, rat TMEM116
  QuantiFast Probe-based Assays in human, mouse, rat TMEM116

Additional mRNA sequence: 

AK074648.1 AK092832.1 AL833501.1 BC000282.1 BC022360.1 BC048796.1 BC070135.1 

19 DOTS entries:

DT.92424246  DT.100791616  DT.102842866  DT.100791618  DT.91979887  DT.95166602  DT.314641  DT.100791619 
DT.121204569  DT.92424251  DT.75129791  DT.121204505  DT.95166601  DT.95166604  DT.121204518  DT.121204568 
DT.92424250  DT.91676912  DT.95166603 

Selected AceView cDNA sequences (see all 123):

BI755241 BQ309764 AA417315 CR612135 BC022360 BM699193 AI208862 BU631241 
BC000282 BM669855 BU607883 BU607447 BU676857 AA442345 F03154 BM979996 
T34718 CD672216 AA904123 N52034 BC048796 AA600964 N54649 AA401532 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

TMEM116 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCCCTTTATG
TMEM116 Expression
About this image

TMEM116 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

TMEM116 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.506815
    Custom PCR Arrays for TMEM116
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM116
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM116
QuantiTect SYBR Green Assays in human, mouse, rat TMEM116
QuantiFast Probe-based Assays in human, mouse, rat TMEM116
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM116

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of chordates.

Orthologs for TMEM116 gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tmem1161 , 5 transmembrane protein 1161, 5 78.34(n)1
70.03(a)1
  5 (61.81 cM)5
774621  NM_001161627.11  NP_001155099.11 
 1214518935 
chicken
(Gallus gallus)
Aves TMEM1161 transmembrane protein 116 63.44(n)
58.12(a)
  416881  XM_004945604.1  XP_004945661.1 
lizard
(Anolis carolinensis)
Reptilia TMEM1166
transmembrane protein 116
53(a)
1 ↔ 1
GL343282.1(75210-95564)
tropical clawed frog
(Xenopus tropicalis)
Amphibia LOC1004873151 transmembrane protein 116-like 54.15(n)
43.69(a)
  100487315  XM_002940124.2  XP_002940170.2 
zebrafish
(Danio rerio)
Actinopterygii si:ch211-157p22.101 si:ch211-157p22.10 53.4(n)
44.75(a)
  100003849  NM_001114707.1  NP_001108179.1 


ENSEMBL Gene Tree for TMEM116 (if available)
TreeFam Gene Tree for TMEM116 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for TMEM116 (see all 1268)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs753530961,2
C,F--112368653(+) TGTTCA/CTACTG 3 -- int11Minor allele frequency- C:0.01NA 120
rs1840506121,2
--112368783(+) TAAATC/TTTATT 3 -- int10--------
rs777163201,2
F--112368822(+) AGTATT/GCTAGA 3 -- int11Minor allele frequency- G:0.01WA 118
rs110660921,2
C,F,H--112368871(+) TGAACA/GTATGA 3 -- int112Minor allele frequency- G:0.28NS EA NA WA 800
rs1455117191,2
--112368872(+) GAACAC/TATGAG 3 -- int10--------
rs123215681,2
F,H--112368927(+) TAGTAG/ATTCTC 3 -- int13Minor allele frequency- A:0.00EA NS 290
rs1425163601,2
C--112369011(+) AGTAAC/TAGCAA 3 -- int10--------
rs101615211,2
C,F,H--112369084(+) AGACAG/ACTTTG 3 -- spd15Minor allele frequency- A:0.02NS EA WA 538
rs169417751,2
C,F,H--112369334(+) ATAGTT/CAGAAA 3 -- ut3111Minor allele frequency- C:0.02NA NS WA 1280
rs2002989811,2
C--112369445(+) AGTACT/AGGCAG 6 /S /C mis11Minor allele frequency- A:0.00EU 1323

HapMap Linkage Disequilibrium report for TMEM116 (112369086 - 112451023 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for TMEM116:    About this table    
Variant IDTypeSubtypePubMed ID
esv2746360CNV Deletion23290073
nsv887CNV Loss18451855

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing TMEM116
DNA2.0 Custom Variant and Variant Library Synthesis for TMEM116

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for TMEM116 gene integrated from 10 sources:
(articles sorted by number of sources associating them with TMEM116)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  6. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 89894 HGNC: 25084 AceView: LOC89894 Ensembl:ENSG00000198270 euGenes: HUgn89894
ECgene: TMEM116 H-InvDB: TMEM116

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for TMEM116 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for TMEM116 gene:
Search GeneIP for patents involving TMEM116

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM116  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TMEM116  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM116  
 OriGene qSTAR qPCR primer pairs in human, mouse for TMEM116   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for TMEM116   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for TMEM116   OriGene Custom Protein Services for TMEM116  

 
 
 Block miRNA regulation of human, mouse, rat TMEM116 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM116
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM116 Predesigned siRNA for gene silencing in human, mouse, rat TMEM116
 QuantiFast Probe-based Assays in human, mouse, rat TMEM116 QuantiTect SYBR Green Assays in human, mouse, rat TMEM116
 Custom PCR Arrays for TMEM116 Search Chromatin IP Primers for TMEM116
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM116  Search GeneGlobe Interaction Network for TMEM116
 Regulatory tfbs in TMEM116 promoter
 GenScript Custom Purified and Recombinant Proteins Services for TMEM116 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM116
 GenScript Custom Assay Services for TMEM116 GenScript Custom overexpressing Cell Line Services for TMEM116
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for TMEM116 (TM116)
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 TMEM116 antibodies
 TMEM116 proteins
 Antibodies for TMEM116
 See all of Abcam's Antibodies, Kits and Proteins for TMEM116
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for TMEM116
 Antibodies for TMEM116
 ELISAs for TMEM116
 CLIAs for TMEM116



 Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM116
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM116
 SwitchGear 3'UTR luciferase reporter plasmids for TMEM116
 SwitchGear Promoter luciferase reporter plasmids for TMEM116
 Search ThermoFisher Antibodies for TMEM116
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM116
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM116
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM116
 LSBio Antibodies in human, mouse, rat for TMEM116
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for TMEM116
  Search eBioscience for proteins for TMEM116
  Search eBioscience for elisas for TMEM116
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      TMEM116 gene at Home site.
Version: 3.12.212 17 Sep 2014
hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4