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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM115 Gene

protein-coding   GIFtS: 46
GCID: GC03M050392

transmembrane protein 115
 Explore 3 diseases affiliated with
TMEM115 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TMEM115    

Aliases
for TMEM115 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Transmembrane Protein 1151 2
PL61 2 3
Placental Protein 62 3
PP62 3
Protein PL63

External Ids:    HGNC: 300551   Entrez Gene: 110702   Ensembl: ENSG000001260627   OMIM: 6070695   UniProtKB: Q128933   

Export aliases for TMEM115 gene to outside databases

Previous GC identifer: GC03M050368


Summaries
for TMEM115 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for TMEM115 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM115 gene promoter:
         AhR   c-Jun   Nkx2-5   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMEM115 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMEM115

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM115


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.31

TMEM115 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM115 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M050392:  view genomic region     (about GC identifiers)

Start:
 50,392,180 bp from pter      End:
 50,397,041 bp from pter
Size:
 4,862 bases      Orientation:
 minus strand

Proteins
for TMEM115 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TM115_HUMAN, Q12893 (See protein sequence)
Recommended Name: Transmembrane protein 115  
Size: 351 amino acids; 38197 Da
Subcellular location: Membrane; Multi-pass membrane protein (Probable)
Sequence caution: Sequence=AAB67308.1; Type=Erroneous gene model prediction;
Secondary accessions: A2IDB7 O14568 Q6IAY4 Q9UIX3

Explore the universe of human proteins at neXtProt for TMEM115: NX_Q12893

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q12893

    • TMEM115 Protein expression data from MOPED and PaxDb:    About this image 
    TMEM115 Protein Expression
    REFSEQ proteins: NP_008955.1  
    ENSEMBL proteins: 
     ENSP00000266025  

    Human Recombinant Protein Products for TMEM115: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate: TMEM115
    OriGene Custom Protein Services for TMEM115 
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    Novus Biologicals TMEM115 Protein
    Novus Biologicals TMEM115 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TMEM115

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA17973242
    GO:0005794Golgi apparatus IDA17973242
    GO:0016021integral to membrane IEA--

    TMEM115 for ontologies           About GeneDecksing



    TMEM115 Antibody Products: 
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    Uscn ELISAs and CLIAs for TMEM115

    Protein Domains /
    Families
    for TMEM115 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TMEM115 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR013861 DUF1751_Mem_euk

    Graphical View of Domain Structure for InterPro Entry Q12893

    ProtoNet protein and cluster: Q12893

    1 Blocks protein family: IPB013861 Protein of unknown function DUF1751


    Function
    for TMEM115 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    TMEM115 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TMEM115 

    miRNA
    Products:            		 OriGene 3'-UTR Clone: TMEM115
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM115
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM115 (see all 18):
    hsa-miR-140-5p hsa-miR-142-3p hsa-miR-642a hsa-miR-185* hsa-miR-4288 hsa-miR-1271 hsa-miR-632 hsa-miR-24
    SwitchGear 3'UTR luciferase reporter plasmid: TMEM115 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM115 (see all 7)
    OriGene shRNA RFP: TMEM115
    OriGene siRNA: TMEM115
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM115
    Sirion Biotech Custom design and validation of potent shRNA sequences against TMEM115 

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TMEM115
    Sirion Biotech Customized adenovirus for overexpression of TMEM115 
    Sirion Biotech Customized adenovirus for potent knockdown of TMEM115

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM115 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM115
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TMEM115 (NM_007024)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM115
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM115 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for TMEM115
    Search LifeMap BioReagents cell lines for TMEM115
    Sirion Biotech Customized stable knockdown cell line services for TMEM115 
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    Sirion Biotech Customized inducible overexpressing cell line services for TMEM115

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM115


    Pathways & Interactions
    for TMEM115 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM115

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/7 Interacting proteins for TMEM115 (Q128933 ENSP000002660254) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K7O433183, ENSP000003583354I2D: score=1 STRING: ENSP00000358335
    TAB2Q9NYJ83, ENSP000002863324I2D: score=1 STRING: ENSP00000286332
    GIPC1O149083I2D: score=2 
    CREB3O438893I2D: score=1 
    TNFP013753I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001302replicative cell aging ----
    GO:0008285negative regulation of cell proliferation NAS17973242

    TMEM115 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TMEM115 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM115
    Search CenterWatch for drugs/clinical trials and news about TMEM115 / TM115 

    Transcripts
    for TMEM115 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TMEM115 gene: 
    NM_007024.4  

    Unigene Cluster for TMEM115:

    Transmembrane protein 115
    Hs.91566  [show with all ESTs]
    Unigene Representative Sequence: NM_007024
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000266025(uc003dan.1)

    miRNA
    Products:             		 OriGene 3'-UTR Clone: TMEM115
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM115
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM115 (see all 18):
    hsa-miR-140-5p hsa-miR-142-3p hsa-miR-642a hsa-miR-185* hsa-miR-4288 hsa-miR-1271 hsa-miR-632 hsa-miR-24
    SwitchGear 3'UTR luciferase reporter plasmid: TMEM115 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM115 (see all 7)
    OriGene shRNA RFP: TMEM115
    OriGene siRNA: TMEM115
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM115
    Sirion Biotech Custom design and validation of potent shRNA sequences against TMEM115 
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM115 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM115
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TMEM115 (NM_007024)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM115
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM115 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM115
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM115
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM115
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM115

    Additional cDNA sequence: 

    AK314166.1 BC011948.1 BC017367.2 CR457020.1 U09584.1 

    9 DOTS entries:

    DT.456391  DT.100759142  DT.95120336  DT.100797508  DT.100797501  DT.100797503  DT.100649100  DT.100698623 
    DT.120873153 

    24/194 AceView cDNA sequences (see all 194):

    AW583719 BU541135 AI857851 CA417128 NM_007024 BQ636103 AI934503 AA456583 
    BQ006065 CR605338 BU620150 CA309470 BC011948 CR599068 CR457020 AA335695 
    BM727875 CD370141 CF132346 AA631003 CR592998 BM994890 AI075355 AI570629 

    GeneLoc Exon Structure


    Expression
    for TMEM115 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMEM115 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCTTCTGCT
    TMEM115 Expression
    About this image

    TMEM115 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    HeartAtrioventricular CanalAtrioventricular Canal CellsMyocardium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TMEM115 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMEM115

    SOURCE GeneReport for Unigene cluster: Hs.91566

    UniProtKB/Swiss-Prot: TM115_HUMAN, Q12893
    Tissue specificity: Expressed strongly in kidney and skeletal muscle, followed by liver, placenta, pancreas, and lung,
    with low amounts in heart and only traces in brain

        SABiosciences Custom PCR Arrays for TMEM115
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM115
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM115
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM115

    Orthologs
    for TMEM115 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TMEM115 gene from 10/30 species (see all 30)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Tmem1151 , 5 transmembrane protein 1151, 5 88.31(n)1
    94.83(a)1    		   9 (58.12 cM)5
    563951  NM_019704.21  NP_062678.11 
     1075339455 
    chicken
    (Gallus gallus)    		 Aves TMEM1151 transmembrane protein 115 77.83(n)
    78.26(a)    		   429757  XM_003641970.1  XP_003642018.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TMEM1156
    		 --
    		 78(a)
    		 1 ↔ 1
    		 2(150125883-150132452)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia 1419972512   -- 75.21(n)    141997251 
    zebrafish
    (Danio rerio)    		 Actinopterygii BM140792.12   -- 71.47(n)    BM140792.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG95361 CG9536 52.68(n)
    40.27(a)    		   33904  NM_001201777.1  NP_001188706.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea F11A10.61 Protein F11A10.6 40.07(n)
    28.31(a)    		   178149  NM_069891.5  NP_502292.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes (YOL107W)4
    YOL107W1    		 Putative protein of unknown function; green fluorescent more4
    hypothetical protein1    		 40.69(n)1
    27.92(a)1    		   15(112102-113130)4
    8540431, 4  NP_014534.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G079501 rhomboid protein-like protein 45.02(n)
    35.46(a)    		   819986  NM_111674.2  NP_566326.1 
    rice
    (Oryza sativa)    		 Liliopsida Os07g06554001 hypothetical protein 43.96(n)
    34.07(a)    		   4344140  NM_001067031.1  NP_001060496.1 


    ENSEMBL Gene Tree for TMEM115 (if available)
    TreeFam Gene Tree for TMEM115 (if available) 

    Paralogs
    for TMEM115 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for TMEM115 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/106 NCBI SNPs in TMEM115 are shown (see all 106)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1453837111,2
    		--50392035(+) ATGTGA/GTGGTG 1 -- int10--------
    rs768216011,2
    		F--50392049(+) GTGGCG/AGTGGT 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1877115801,2
    		--50392218(+) CGAGCC/G/TTGGGC 2 -- ut310--------
    rs10518451,2
    		C--50392251(-) ATTTTC/TTACAG 1 -- ut31 ese32Minor allele frequency- T:0.00MN NA 186
    rs1922585481,2
    		--50392282(+) CTGGTC/TCAGAA 1 -- ut310--------
    rs1143896841,2
    		C,F--50392370(+) CAGGTC/TGGCTC 1 -- ut311Minor allele frequency- T:0.02WA 118
    rs1172409081,2
    		--50392440(+) CGGCAA/GCCAGT 1 -- ut311Minor allele frequency- G:0.01EA 120
    rs1844082511,2
    		--50392459(+) TGAGGA/GCCGGC 1 -- ut310--------
    rs790125481,2
    		--50392469(+) CCCAGG/CAGCTG 1 -- ut311Minor allele frequency- C:0.50CSA 2
    rs1424803591,2
    		--50392473(+) GGAGCC/TGTGGC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TMEM115 (50392180 - 50397041 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for TMEM115
         3 CNVs: 30176 4335 4336

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM115
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM115

    Disorders / Diseases
    for TMEM115 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TMEM115 for disorders           About GeneDecksing

    OMIM gene information: 607069    OMIM disorders: --

    3 diseases for TMEM115:    About MalaCards
    renal clear cell carcinoma    lung cancer    carcinoma


    Export disorders for TMEM115 gene to outside databases

    Publications
    for TMEM115 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM115 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TMEM115)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. (PubMed id 11085536)1, 2, 3 Lerman M.I. and Minna J.D. (2000)
    2. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)1, 2 Muzny D.M....Gibbs R.A. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    5. Loss of PL6 protein expression in renal clear cell carcinomas and other VHL-deficient tumours. (PubMed id 17973242)1 Ivanova A.V....Lerman M.I. (2008)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
    8. A family of cAMP-binding proteins that directly activate rap1. (PubMed id 9856955)1 Kawasaki H.... Graybiel A.M. (1998)

    External Searches for TMEM115 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
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    Genome Databases showing TMEM115 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11070 HGNC: 30055 AceView: PL6 Ensembl:ENSG00000126062 euGenes: HUgn11070
    ECgene: TMEM115 H-InvDB: TMEM115

    Other Databases showing TMEM115 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TMEM115 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM115 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TMEM115 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TMEM115 gene:
    Search GeneIP for patents involving TMEM115

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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    About This Section

     
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     TMEM115 Proteins, Antibodies, CLIAs, and ELISAs
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    Sirion Biotech Customized:
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