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Aliases for TMEM110 Gene

Aliases for TMEM110 Gene

  • Transmembrane Protein 110 2 3

External Ids for TMEM110 Gene

Previous GeneCards Identifiers for TMEM110 Gene

  • GC03M052843
  • GC03M052823
  • GC03M052849
  • GC03M052870

Summaries for TMEM110 Gene

GeneCards Summary for TMEM110 Gene

TMEM110 (Transmembrane Protein 110) is a Protein Coding gene. An important paralog of this gene is TMEM110-MUSTN1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM110 Gene

Genomics for TMEM110 Gene

Regulatory Elements for TMEM110 Gene

Genomic Location for TMEM110 Gene

Start:
52,836,219 bp from pter
End:
52,897,596 bp from pter
Size:
61,378 bases
Orientation:
Minus strand

Genomic View for TMEM110 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM110 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM110 Gene

Proteins for TMEM110 Gene

  • Protein details for TMEM110 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86TL2-TM110_HUMAN
    Recommended name:
    Transmembrane protein 110
    Protein Accession:
    Q86TL2
    Secondary Accessions:

    Protein attributes for TMEM110 Gene

    Size:
    294 amino acids
    Molecular mass:
    33187 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM110 Gene

Proteomics data for TMEM110 Gene at MOPED

Post-translational modifications for TMEM110 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM110 Gene

No data available for DME Specific Peptides for TMEM110 Gene

Domains for TMEM110 Gene

Protein Domains for TMEM110 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM110 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM110: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM110 Gene

Function for TMEM110 Gene

Gene Ontology (GO) - Molecular Function for TMEM110 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TMEM110: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM110

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM110 Gene

Localization for TMEM110 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM110 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM110 Gene COMPARTMENTS Subcellular localization image for TMEM110 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM110 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM110: view

Pathways for TMEM110 Gene

SuperPathways for TMEM110 Gene

No Data Available

Interacting Proteins for TMEM110 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000347195%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000347195 for TMEM110 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for TMEM110 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TMEM110: view

No data available for Pathways by source for TMEM110 Gene

Transcripts for TMEM110 Gene

mRNA/cDNA for TMEM110 Gene

Unigene Clusters for TMEM110 Gene

Transmembrane protein 110:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM110

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM110 Gene

No ASD Table

Relevant External Links for TMEM110 Gene

GeneLoc Exon Structure for
TMEM110
ECgene alternative splicing isoforms for
TMEM110

Expression for TMEM110 Gene

mRNA expression in normal human tissues for TMEM110 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM110 Gene

This gene is overexpressed in Whole Blood (5.2).

SOURCE GeneReport for Unigene cluster for TMEM110 Gene Hs.744189

genes like me logo Genes that share expressions with TMEM110: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for TMEM110 Gene

Orthologs for TMEM110 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TMEM110 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM110 36
  • 78 (a)
OneToMany
cow
(Bos Taurus)
Mammalia TMEM110 36
  • 98 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 92 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Tmem110 16
Tmem110 36
  • 98 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 71 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 86 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 81 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 87 (a)
OneToMany
African clawed frog
(Xenopus laevis)
Amphibia Xl.2630 35
zebrafish
(Danio rerio)
Actinopterygii tmem110 36
  • 72 (a)
OneToMany
zgc63630 35
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AAL091C 35
  • 45.79 (n)
  • 32.24 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 26 (a)
OneToMany
YPL162C 35
  • 44.85 (n)
  • 32.46 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C10076g 35
  • 44.08 (n)
  • 30.6 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU02834 35
  • 47.41 (n)
  • 33.47 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 41 (a)
OneToMany
Species with no ortholog for TMEM110:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM110 Gene

ENSEMBL:
Gene Tree for TMEM110 (if available)
TreeFam:
Gene Tree for TMEM110 (if available)

Paralogs for TMEM110 Gene

Paralogs for TMEM110 Gene

Selected SIMAP similar genes for TMEM110 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with TMEM110: view

Variants for TMEM110 Gene

Structural Variations from Database of Genomic Variants (DGV) for TMEM110 Gene

Variant ID Type Subtype PubMed ID
nsv834698 CNV Gain 17160897
nsv508928 CNV Insertion 20534489
nsv876797 CNV Loss 21882294

Relevant External Links for TMEM110 Gene

HapMap Linkage Disequilibrium report
TMEM110
Human Gene Mutation Database (HGMD)
TMEM110

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for TMEM110 Gene

Disorders for TMEM110 Gene

No disorders were found for TMEM110 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM110 Gene

Publications for TMEM110 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) (Nat. Genet. 2011) 3

Products for TMEM110 Gene

Sources for TMEM110 Gene

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