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TMEM11 Gene

protein-coding   GIFtS: 51
GCID: GC17M021042

Transmembrane Protein 11

(Previous name: chromosome 17 open reading frame 35)
(Previous symbol: C17orf35)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 111 2     Putative Receptor Protein2
C17orf351 2 3     Transmembrane Protein 11, Mitochondrial2
PM12 3     Protein PM13
Chromosome 17 Open Reading Frame 351     Protein PMI3
PMI2     TMEM1145

External Ids:    HGNC: 168231   Entrez Gene: 88342   Ensembl: ENSG000001783077   OMIM: 6115795   UniProtKB: P171523   

Export aliases for TMEM11 gene to outside databases

Previous GC identifer: GC17M020303


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM11 Gene:
TMEM11 (transmembrane protein 11) is a protein-coding gene. Diseases associated with TMEM11 include trench fever, and klatskin's tumor.

UniProtKB/Swiss-Prot: TMM11_HUMAN, P17152
Function: Plays a role in mitochondrial morphogenesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010718.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM11 gene promoter:
         Max1   USF1   Tal-1   SREBP-1c   E47   YY1   POU2F1   USF-1   POU2F1a   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM11 promoter sequence
   Search Chromatin IP Primers for TMEM11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p11.2   Ensembl cytogenetic band:  17p11.2   HGNC cytogenetic band: 17p11.1

TMEM11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM11 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M021042:  view genomic region     (about GC identifiers)

Start:
21,100,593 bp from pter      End:
21,117,937 bp from pter
Size:
17,345 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TMM11_HUMAN, P17152 (See protein sequence)
Recommended Name: Transmembrane protein 11, mitochondrial  
Size: 192 amino acids; 21541 Da
Secondary accessions: Q53YB2

Explore the universe of human proteins at neXtProt for TMEM11: NX_P17152

Explore proteomics data for TMEM11 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys142
  • Modification sites at PhosphoSitePlus

  • See TMEM11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003867.1  
    ENSEMBL proteins: 
     ENSP00000319992  

    TMEM11 Human Recombinant Protein Products:

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    TMEM11 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for TMEM11
    Cloud-Clone Corp. CLIAs for TMEM11


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026120 TMEM11

    Graphical View of Domain Structure for InterPro Entry P17152

    ProtoNet protein and cluster: P17152

    UniProtKB/Swiss-Prot: TMM11_HUMAN, P17152
    Similarity: Belongs to the TMEM11 family


    TMEM11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TMM11_HUMAN, P17152
    Function: Plays a role in mitochondrial morphogenesis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI16189514
         
    TMEM11 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TMEM11:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Tmem11 (no phenotypes)

    TMEM11 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM11
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM11

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM11
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM11

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM11:
    hsa-mir-186-5p (MIRT045019)

    Block miRNA regulation of human, mouse, rat TMEM11 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TMEM11
    SwitchGear 3'UTR luciferase reporter plasmidTMEM11 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TMEM11
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM11

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for TMEM11

    Clone
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    OriGene clones in human, mouse for TMEM11 (see all 8)
    OriGene ORF clones in mouse, rat for TMEM11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM11 (NM_003876)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM11

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM11 
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM11


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TMM11_HUMAN, P17152: Mitochondrion inner membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    plasma membrane5
    nucleus2
    peroxisome2
    endoplasmic reticulum1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005887integral component of plasma membrane NAS2110658
    GO:0031305integral component of mitochondrial inner membrane IDA--

    TMEM11 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM11
    Interactions:

        Search GeneGlobe Interaction Network for TMEM11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for TMEM11 (P171521, 2, 3 ENSP000003199924) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSPD1P108092, 3, ENSP000003400194MINT-8152379 MINT-8152405 MINT-8152389 I2D: score=1 STRING: ENSP00000340019
    BNIP3Q129831, 2, 3, ENSP000003576254EBI-723946,EBI-749464 MINT-67537 I2D: score=6 STRING: ENSP00000357625
    BNIP3LO602382, 3, ENSP000003700034MINT-67952 I2D: score=5 STRING: ENSP00000370003
    SCMH1Q96GD32, 3, ENSP000003180944MINT-63513 I2D: score=4 STRING: ENSP00000318094
    ATP5A1P257053, ENSP000002820504I2D: score=1 STRING: ENSP00000282050
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007005mitochondrion organization IMP--

    TMEM11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM11 (TMM11)

    1 Novoseek inferred chemical compound relationship for TMEM11 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 0 2 15258259 (1), 10913346 (1)



    TMEM11 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TMEM11 gene: 
    NM_003876.2  

    Unigene Cluster for TMEM11:

    Transmembrane protein 11
    Hs.592945  [show with all ESTs]
    Unigene Representative Sequence: NR_024547
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000317635(uc002gyq.2 uc002gyp.2) ENST00000584432 ENST00000577419
    ENST00000583264 ENST00000583929 ENST00000584732
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM11 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TMEM11
    SwitchGear 3'UTR luciferase reporter plasmidTMEM11 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM11
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM11
    Clone
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    OriGene clones in human, mouse for TMEM11 (see all 8)
    OriGene ORF clones in mouse, rat for TMEM11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM11 (NM_003876)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM11
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM11
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM11
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM11
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM11
      QuantiFast Probe-based Assays in human, mouse, rat TMEM11

    Additional mRNA sequence: 

    AK311965.1 BC002819.2 BC005268.1 BC020815.1 BC035874.1 BT006768.1 NR_024547.1 X51804.1 

    6 DOTS entries:

    DT.446669  DT.97785235  DT.92428976  DT.100691825  DT.40206372  DT.95091220 

    Selected AceView cDNA sequences (see all 288):

    BF115001 CR606340 AI434762 BX646938 BM825743 CK822359 CR623488 CR611577 
    AI421096 BI858662 AA342588 BM824339 CA423011 BI253680 CR625355 AA702837 
    BQ937961 BQ430679 BG258157 CD172380 F04782 BU732945 BQ447545 BU169297 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM11    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c
    SP1:                                -                     
    SP2:                                                      
    SP3:                          -     -                     
    SP4:                    -     -     -                     


    ECgene alternative splicing isoforms for TMEM11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGATCTACAA
    TMEM11 Expression
    About this image

    TMEM11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.592945
        Custom PCR Arrays for TMEM11
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TMEM11 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem111 , 5 transmembrane protein 111, 5 91.23(n)1
    97.89(a)1
      11 (37.90 cM)5
    2168211  NM_173453.31  NP_775655.11 
     608644525 
    chicken
    (Gallus gallus)
    Aves TMEM111 transmembrane protein 11 87.5(n)
    95.83(a)
      427663  NM_001031466.1  NP_001026637.1 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM116
    transmembrane protein 11
    90(a)
    1 ↔ 1
    GL343385.1(837192-842904)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.149272 Xenopus laevis transcribed sequence with moderate similarity to protein pirS15930 (H.sapiens) S15930 hypothetical 21.5K G protein-coupled receptor - human less 81.23(n)    BM180707.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.168782 Transcribed sequence with moderate similarity to protein pirS15930 (H.sapiens) S15930 hypothetical 21.5K G protein-coupled receptor - human less 79.89(n)    CD751605.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pmi1 Pmi 54.78(n)
    46.5(a)
      3772100  NM_001031939.2  NP_001027110.2 


    ENSEMBL Gene Tree for TMEM11 (if available)
    TreeFam Gene Tree for TMEM11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM11 (see all 408)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1476691281,2
    C--21100793(+) AGGCC-/AGGGGG 2 -- ds50010--------
    rs1888800721,2
    --21100806(+) CTTCCA/TAGATT 2 -- ds50010--------
    rs1161049061,2
    C,F--21100839(+) CCTAGG/AGCAAT 2 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1147816411,2
    F--21100845(+) GCAATG/AGGTTA 2 -- ds50011Minor allele frequency- A:0.01WA 118
    rs669742581,2
    C,F--21100934(+) CTGGAG/ACCCAG 2 -- ds50018Minor allele frequency- A:0.37NA WA CSA EA 370
    rs1123705751,2
    C--21100987(+) GCCTCG/ATCACC 2 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1390215061,2
    --21101028(+) GGCAGC/TGATGG 2 -- ds50010--------
    rs1813515411,2
    --21101080(+) CTGGGC/TGGGGT 2 -- ds50010--------
    rs783695181,2
    F--21101202(+) GCAAGC/ACGCCA 2 -- ds50011Minor allele frequency- A:0.04WA 118
    rs778890551,2
    C,F--21101206(+) GCCGCC/AACCCA 2 -- ds50012Minor allele frequency- A:0.06WA 120

    HapMap Linkage Disequilibrium report for TMEM11 (21100593 - 21117937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TMEM11:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2665619CNV Deletion23128226
    nsv907885CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM11
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611579    OMIM disorders: --

    10 diseases for TMEM11:    About MalaCards
    trench fever    klatskin's tumor    neuronal ceroid lipofuscinosis    polymyositis
    polycystic kidney disease    dermatomyositis    kidney disease    malaria
    neuronitis    leukemia

    2 diseases from the University of Copenhagen DISEASES database for TMEM11:
    Dermatomyositis     Klatskin's tumor

    TMEM11 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for TMEM11 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia 7.44 1 8397366 (1)

    Genetic Association Database (GAD): TMEM11
    Human Genome Epidemiology (HuGE) Navigator: TMEM11 (1 document)

    Export disorders for TMEM11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM11 gene, integrated from 10 sources (see all 36):
    (articles sorted by number of sources associating them with TMEM11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways. (PubMed id 21274005)1, 2, 3 Rival T.... Royet J. (EMBO Rep. 2011)
    2. Nucleotide sequence of a cDNA encoding a protein with primary structural similarity to G-protein coupled receptors. (PubMed id 2110658)1, 2, 3 Murphy P.M. and Malech H.L. (Nucleic Acids Res. 1990)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis. (PubMed id 23142642)1 Passantino R....Guarneri P. (Biochim. Biophys. Acta 2013)
    6. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    7. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8834 HGNC: 16823 AceView: C17orf35andMGC33894 Ensembl:ENSG00000178307 euGenes: HUgn8834
    ECgene: TMEM11 H-InvDB: TMEM11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM11 gene:
    Search GeneIP for patents involving TMEM11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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