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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM108 Gene

protein-coding   GIFtS: 46
GCID: GC03P132757

transmembrane protein 108
  Search for TMEM108
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TMEM108    

Aliases
for TMEM108 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Transmembrane Protein 1081 2
CT1241 2
MGC30401
Cancer/Testis Antigen 1242
KIAA16903

External Ids:    HGNC: 284511   Entrez Gene: 660002   Ensembl: ENSG000001448687   UniProtKB: Q6UXF13   

Export aliases for TMEM108 gene to outside databases

Previous GC identifers: GC03P134240 GC03P130137


Summaries
for TMEM108 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for TMEM108 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM108 gene promoter:
         Egr-3   Tal-1   NF-kappaB   HNF-1A   C/EBPalpha   E47   Evi-1   AREB6   HNF-1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMEM108 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMEM108

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM108


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21   Ensembl cytogenetic band:  3q22.1   HGNC cytogenetic band: 3q21

TMEM108 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM108 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P132757:  view genomic region     (about GC identifiers)

Start:
 132,757,171 bp from pter      End:
 133,116,636 bp from pter
Size:
 359,466 bases      Orientation:
 plus strand

Proteins
for TMEM108 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TM108_HUMAN, Q6UXF1 (See protein sequence)
Recommended Name: Transmembrane protein 108 precursor  
Size: 575 amino acids; 59948 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: D3DNC9 Q9BQH1 Q9BW81 Q9C0H3
Alternative splicing: 2 isoforms:  Q6UXF1-1   Q6UXF1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM108: NX_Q6UXF1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6UXF1

    • TMEM108 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001129941.1  NP_076432.1  

    ENSEMBL proteins: 
     ENSP00000324651   ENSP00000376838   ENSP00000422072   ENSP00000427447   ENSP00000426301  
     ENSP00000422196   ENSP00000424897   ENSP00000423338   ENSP00000421486  

    Human Recombinant Protein Products: 
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    OriGene Custom Protein Services for TMEM108 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TMEM108

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0016021integral to membrane IEA--


    TMEM108 for ontologies           About GeneDecksing



    TMEM108 Antibody Products: 
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    Uscn Antibodies for TMEM108
    ThermoFisher Antibodies for TMEM108

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    Uscn ELISAs and CLIAs for TMEM108

    Protein Domains /
    Families
    for TMEM108 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q6UXF1


    Function
    for TMEM108 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 2): TMEM108
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM108
    8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM108 (see all 39):
    hsa-miR-576-3p hsa-miR-142-5p hsa-miR-3607-3p hsa-miR-4272 hsa-miR-485-3p hsa-miR-374a hsa-miR-3921 hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmid: TMEM108 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM108 (see all 3)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM108

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TMEM108

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM108 (see all 3)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM108 (NM_023943)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM108
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM108 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for TMEM108
    LifeMap BioReagents: cell line associated with TMEM108: PureStem ES-210, Ecto-ntu Progenitor

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM108

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    TMEM108 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Tmem108tm1Lex for TMEM108
         1 MGI phenotypic allele for Tmem108 (no phenotypes)

    TMEM108 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TMEM108 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM108

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5 Interacting proteins for TMEM108 (Q6UXF12, 3 ENSP000003246514) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARHGEF6Q150522, 3, ENSP000002506174MINT-8249080 I2D: score=2 STRING: ENSP00000250617
    ANXA7P200732, 3MINT-8248794 I2D: score=2 
    SH3GL2Q999622, 3, ENSP000003699814MINT-8270605 I2D: score=2 STRING: ENSP00000369981
    PLSCR1O151623I2D: score=1 
    WDR6Q9NNW53I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--


    TMEM108 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TMEM108 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM108
    Search CenterWatch for drugs/clinical trials and news about TMEM108 / TM108 

    Transcripts
    for TMEM108 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TMEM108 gene (2 alternative transcripts): 
    NM_001136469.1  NM_023943.2  

    Unigene Cluster for TMEM108:

    Transmembrane protein 108
    Hs.191616  [show with all ESTs]
    Unigene Representative Sequence: AB051477
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514529 ENST00000321871(uc003epi.3 uc003eph.3) ENST00000393130
    ENST00000514894 ENST00000512662 ENST00000512137 ENST00000511555 ENST00000508711(uc003epk.3)
    ENST00000515826(uc003epj.1) ENST00000510183 ENST00000511388

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): TMEM108
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM108
    8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM108 (see all 39):
    hsa-miR-576-3p hsa-miR-142-5p hsa-miR-3607-3p hsa-miR-4272 hsa-miR-485-3p hsa-miR-374a hsa-miR-3921 hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmid: TMEM108 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM108 (see all 3)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM108
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM108 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM108 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM108 (NM_023943)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM108
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM108 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM108
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM108
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM108
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM108

    Additional cDNA sequence: 

    AB051477.1 AK095050.1 AL136578.1 AY358381.1 BC000568.2 

    7 DOTS entries:

    DT.210689  DT.92426653  DT.100688001  DT.95235418  DT.100721277  DT.307874  DT.92426658 

    24/102 AceView cDNA sequences (see all 102):

    BU187890 BG721456 BM466403 BC000568 NM_023943 BF727434 BM011053 CR609282 
    BM508041 BM511570 AL136578 CR618323 AI634513 AI348310 BM729904 BI769217 
    AL521386 CD358225 AI377405 AK095050 BM667108 BF313692 AW418761 BQ638156 

    GeneLoc Exon Structure


    Expression
    for TMEM108 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMEM108 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TATATATAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TMEM108 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainCerebral CortexBrain
    BrainChoroid PlexusBrain
    KidneyS-shaped BodyKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor SK17 (Embryonic Progenitor Cell)

    See TMEM108 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMEM108

    SOURCE GeneReport for Unigene cluster: Hs.191616
        SABiosciences Custom PCR Arrays for TMEM108
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM108
    Browse OriGene validated miRNA SYBR primer pairs
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM108
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM108

    Orthologs
    for TMEM108 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM108 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Tmem1081 , 5 transmembrane protein 1081, 5 81.68(n)1
    77.14(a)1    		   9 (55.47 cM)5
    819071  NM_178638.41  NP_848753.11 
     1034829365 
    chicken
    (Gallus gallus)    		 Aves TMEM1081 transmembrane protein 108 61.17(n)
    56.31(a)    		   420692  XM_418792.3  XP_418792.2 
    lizard
    (Anolis carolinensis)    		 Reptilia TMEM1086
    		 --
    		 62(a)
    		 1 ↔ 1
    		 GL343224.1(2360180-2376798)
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.101852 Transcribed sequences 72.88(n)    57080000 


    ENSEMBL Gene Tree for TMEM108 (if available)
    TreeFam Gene Tree for TMEM108 (if available) 

    Paralogs
    for TMEM108 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for TMEM108 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6546 NCBI SNPs in TMEM108 are shown (see all 6546)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1446910571,2
    		C,other133109080(+) CGGAGA/GACAAC 4 N D mis10--------
    rs1130054701,2
    		C--130489812(+) CTGTTC/TCTGGG 1 -- int10--------
    rs1434674691,2
    		--132755196(+) ATGCTC/GAAATG 2 -- us2k10--------
    rs1827836021,2
    		--132755489(+) TGTTGC/TAGAGT 2 -- us2k10--------
    rs1883049971,2
    		--132755519(+) AATGCA/GTCTAT 2 -- us2k10--------
    rs1378884991,2
    		--132755675(+) ATACTA/TACCAT 2 -- us2k10--------
    rs1424121831,2
    		--132755792(+) GAACCA/TTTGCT 2 -- us2k10--------
    rs1157905001,2
    		--132755964(+) CTAAGC/TGACAG 2 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1927882261,2
    		--132756085(+) CACGGC/TGGTAC 2 -- us2k10--------
    rs342987591,2
    		C,--132756105(+) TAATA-/AGAGCTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM108 (132757171 - 133007171 bp, first 250kb of TMEM108)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 9 variations for TMEM108
         6 CNVs: 91566 2474 36069 79912 63595 91565
         3 Indels: 60435 98454 11211

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM108
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM108

    Disorders / Diseases
    for TMEM108 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TMEM108 for disorders           About MalaCards

    TMEM108 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: TMEM108 (3 documents)

    Export disorders for TMEM108 gene to outside databases

    Publications
    for TMEM108 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM108 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with TMEM108)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    5. A genome-wide meta-analysis of genetic variants associ ated with allergic rhinitis and grass sensitization and their interaction with b irth order. (PubMed id 22036096)1 Ramasamy A....Jarvis D.L. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    8. Thirty new loci for age at menarche identified by a m eta-analysis of genome-wide association studies. (PubMed id 21102462)1 Elks C.E....Murray A. (2010)
    9. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1 Uhl G.R....Lerman C. (2008)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    External Searches for TMEM108 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TMEM108 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 66000 HGNC: 28451 AceView: MGC3040 Ensembl:ENSG00000144868 euGenes: HUgn66000
    ECgene: TMEM108 H-InvDB: TMEM108

    Other Databases showing TMEM108 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1690

    Specialized Databases showing TMEM108 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM108 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TMEM108 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TMEM108 gene:
    Search GeneIP for patents involving TMEM108

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     TMEM108 Proteins, Antibodies, CLIAs, and ELISAs
     Cell Line associated with TMEM108: PureStem ES-210, Ecto-ntu Progenitor
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM108
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM108
     SwitchGear Promoter luciferase reporter plasmids for TMEM108
     ThermoFisher Antibodies for TMEM108
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM108
           
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