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TMEM108 Gene

protein-coding   GIFtS: 50
GCID: GC03P132757

Transmembrane Protein 108

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 1081 2
Cancer/Testis Antigen 1241 2
CT1242
KIAA16903

External Ids:    HGNC: 284511   Entrez Gene: 660002   Ensembl: ENSG000001448687   UniProtKB: Q6UXF13   

Export aliases for TMEM108 gene to outside databases

Previous GC identifers: GC03P134240 GC03P130137


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM108 Gene:
TMEM108 (transmembrane protein 108) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM108 gene promoter:
         Egr-3   Tal-1   NF-kappaB   HNF-1A   C/EBPalpha   E47   Evi-1   AREB6   HNF-1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM108 promoter sequence
   Search Chromatin IP Primers for TMEM108

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM108


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21   Ensembl cytogenetic band:  3q22.1   HGNC cytogenetic band: 3q21

TMEM108 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM108 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P132757:  view genomic region     (about GC identifiers)

Start:
132,757,171 bp from pter      End:
133,116,636 bp from pter
Size:
359,466 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TM108_HUMAN, Q6UXF1 (See protein sequence)
Recommended Name: Transmembrane protein 108 precursor  
Size: 575 amino acids; 59948 Da
Secondary accessions: D3DNC9 Q9BQH1 Q9BW81 Q9C0H3
Alternative splicing: 2 isoforms:  Q6UXF1-1   Q6UXF1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM108: NX_Q6UXF1

Explore proteomics data for TMEM108 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn178, Asn223, Asn261, Asn446
  • Modification sites at PhosphoSitePlus

  • See TMEM108 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001129941.1  NP_001269794.1  NP_076432.1  

    ENSEMBL proteins: 
     ENSP00000324651   ENSP00000376838   ENSP00000422072   ENSP00000427447   ENSP00000426301  
     ENSP00000422196   ENSP00000424897   ENSP00000423338   ENSP00000421486  

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    Cloud-Clone Corp. Proteins for TMEM108

     
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    Search eBioscience for ELISAs for TMEM108 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q6UXF1


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with TMEM108           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Tmem108 (no phenotypes)

    Find genes that share phenotypes with TMEM108           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Tmem108tm1Lex for TMEM108

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM108
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM108

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM108
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM108

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM108:
    hsa-mir-183-5p (MIRT047062)

    Block miRNA regulation of human, mouse, rat TMEM108 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM108 (see all 39):
    hsa-miR-576-3p hsa-miR-142-5p hsa-miR-3607-3p hsa-miR-4272 hsa-miR-485-3p hsa-miR-374a hsa-miR-3921 hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmidTMEM108 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TMEM108
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM108

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for TMEM108 (see all 11)
    OriGene ORF clones in mouse, rat for TMEM108
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    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM108 (NM_023943)
    Sino Biological Human cDNA Clone for TMEM108
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM108

    Cell Line
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    ESI BIO PureStem Progenitor for TMEM108: 
    PureStem ES-210, Ecto-ntu Progenitor
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM108


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM108_HUMAN, Q6UXF1: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM108           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM108
    Interactions:

        Search GeneGlobe Interaction Network for TMEM108

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5 Interacting proteins for TMEM108 (Q6UXF12, 3 ENSP000003246514) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARHGEF6Q150522, 3, ENSP000002506174MINT-8249080 I2D: score=2 STRING: ENSP00000250617
    ANXA7P200732, 3MINT-8248794 I2D: score=2 
    SH3GL2Q999622, 3, ENSP000003699814MINT-8270605 I2D: score=2 STRING: ENSP00000369981
    PLSCR1O151623I2D: score=1 
    WDR6Q9NNW53I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with TMEM108           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM108 (TM108)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM108 gene (3 alternative transcripts): 
    NM_001136469.2  NM_001282865.1  NM_023943.3  

    Unigene Cluster for TMEM108:

    Transmembrane protein 108
    Hs.191616  [show with all ESTs]
    Unigene Representative Sequence: AB051477
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514529 ENST00000321871(uc003epi.3 uc003eph.3) ENST00000393130
    ENST00000514894 ENST00000512662 ENST00000512137 ENST00000511555 ENST00000508711(uc003epk.3)
    ENST00000515826(uc003epj.1) ENST00000510183 ENST00000511388
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM108 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM108 (see all 39):
    hsa-miR-576-3p hsa-miR-142-5p hsa-miR-3607-3p hsa-miR-4272 hsa-miR-485-3p hsa-miR-374a hsa-miR-3921 hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmidTMEM108 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM108
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM108
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    OriGene clones in human, mouse for TMEM108 (see all 11)
    OriGene ORF clones in mouse, rat for TMEM108
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM108 (NM_023943)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM108
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM108
    Primer
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    OriGene qPCR primer pairs and template standards for TMEM108
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM108
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM108
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM108
      QuantiFast Probe-based Assays in human, mouse, rat TMEM108

    Additional mRNA sequence: 

    AB051477.1 AK095050.1 AL136578.1 AY358381.1 BC000568.2 

    7 DOTS entries:

    DT.210689  DT.92426653  DT.100688001  DT.95235418  DT.100721277  DT.307874  DT.92426658 

    Selected AceView cDNA sequences (see all 102):

    NM_023943 BM466403 CR618323 BI769217 BM508041 CD358225 BM729904 AI348310 
    AL136578 BF727434 AI634513 BG721456 BC000568 AL521386 BM011053 CR609282 
    BU187890 BM511570 AA894466 BE220565 BG911598 BI544535 BE220400 AW418761 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM108 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATATATAAA
    TMEM108 Expression
    About this image


    TMEM108 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Epithelial Cells
             Podocytes Podocyte Layer
     
     Kidney (Urinary System)
             Podocytes Podocyte Layer
     
     Eye (Sensory Organs)
             Retina
    TMEM108 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM108 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.191616
        Custom PCR Arrays for TMEM108
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM108

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM108 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1081 , 5 transmembrane protein 1081, 5 81.24(n)1
    75.78(a)1
      9 (55.47 cM)5
    819071  NM_178638.41  NP_848753.11 
     1034829365 
    chicken
    (Gallus gallus)
    Aves TMEM1081 transmembrane protein 108 63.04(n)
    60.6(a)
      420692  XM_004939451.1  XP_004939508.1 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM1086
    transmembrane protein 108
    51(a)
    1 ↔ 1
    GL343224.1(2360180-2388381)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem1081 transmembrane protein 108 62.03(n)
    62.55(a)
      100488312  XM_002937746.2  XP_002937792.2 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.101852 Transcribed sequences 72.88(n)    57080000 


    ENSEMBL Gene Tree for TMEM108 (if available)
    TreeFam Gene Tree for TMEM108 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM108 (see all 7604)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1446910571,2
    Cuntested1133109080(+) CGGAGA/GACAAC 4 N D mis10--------
    rs716240111,2
    C--130370019(+) AATGT-/AC    
       
    /ACAC
    ACACA
    2 -- int11NA 2
    rs1434674691,2
    --132755196(+) ATGCTC/GAAATG 2 -- us2k10--------
    rs1827836021,2
    --132755489(+) TGTTGC/TAGAGT 2 -- us2k10--------
    rs1883049971,2
    --132755519(+) AATGCA/GTCTAT 2 -- us2k10--------
    rs1378884991,2
    --132755675(+) ATACTA/TACCAT 2 -- us2k10--------
    rs1424121831,2
    --132755792(+) GAACCA/TTTGCT 2 -- us2k10--------
    rs1157905001,2
    C,F--132755964(+) CTAAGC/TGACAG 2 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1927882261,2
    --132756085(+) CACGGC/TGGTAC 2 -- us2k10--------
    rs342987591,2
    C--132756105(+) TAATA-/AGAGCTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM108 (132757171 - 133007171 bp, first 250kb of TMEM108)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TMEM108 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2725937CNV Deletion23290073
    esv2725936CNV Deletion23290073
    esv2659873CNV Deletion23128226
    esv2669013CNV Deletion23128226
    esv2635909CNV Insertion19546169
    esv32760CNV Loss17666407
    esv28544CNV Loss19812545
    nsv460857CNV Loss19166990
    nsv4016CNV Loss18451855
    esv9637CNV Gain19470904

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM108
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM108

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TMEM108           About GenesLikeMe

    Genetic Association Database (GAD): TMEM108
    Human Genome Epidemiology (HuGE) Navigator: TMEM108 (3 documents)

    Export disorders for TMEM108 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM108 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with TMEM108)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (PubMed id 21102462)1, 4 Elks C.E....Murray A. (Nat. Genet. 2010)
    4. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (Arch. Gen. Psychiatry 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    8. A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. (PubMed id 21529783)1 Heath A.C....Montgomery G.W. (Biol. Psychiatry 2011)
    9. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    10. A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. (PubMed id 22036096)1 Ramasamy A....Jarvis D.L. (J. Allergy Clin. Immunol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 66000 HGNC: 28451 AceView: MGC3040 Ensembl:ENSG00000144868 euGenes: HUgn66000
    ECgene: TMEM108 H-InvDB: TMEM108

    (According to HUGE)
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    HUGE: KIAA1690

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM108 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TMEM108 gene:
    Search GeneIP for patents involving TMEM108

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     PureStem Progenitor for TMEM108: PureStem ES-210, Ecto-ntu Progenitor
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