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TMEM107 Gene

protein-coding   GIFtS: 42
GCID: GC17M008187

Transmembrane Protein 107

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Transmembrane Protein 1071 2
GRVS6382
PRO12682

External Ids:    HGNC: 281281   Entrez Gene: 843142   Ensembl: ENSG000001790297   UniProtKB: Q6UX403   
ORGUL members:         

Export aliases for TMEM107 gene to outside databases

Previous GC identifers: GC17M008027 GC17M008028 GC17M008077 GC17M008080 GC17M008082 GC17M008085 GC17M008113


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM107 Gene:
TMEM107 (transmembrane protein 107) is a protein-coding gene. Diseases associated with TMEM107 include neuronal ceroid lipofuscinosis, and neuronitis.

UniProtKB/Swiss-Prot: TM107_HUMAN, Q6UX40
Function: Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh)
signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate
neuronal cell types (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010718.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM107 gene promoter:
         Pbx1a   AP-1   NF-YC   MIF-1   CUTL1   Nkx2-5   CBF-A   Zic3   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM107 promoter sequence
   Search Chromatin IP Primers for TMEM107

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM107


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

TMEM107 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM107 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M008187:  view genomic region     (about GC identifiers)

Start:
8,076,296 bp from pter      End:
8,079,717 bp from pter
Size:
3,422 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TM107_HUMAN, Q6UX40 (See protein sequence)
Recommended Name: Transmembrane protein 107  
Size: 140 amino acids; 15503 Da
Sequence caution: Sequence=AAK38512.1; Type=Frameshift; Positions=63, 82;
Secondary accessions: A0PJV7 Q6NSE3 Q6ZRX9 Q96T82
Alternative splicing: 4 isoforms:  Q6UX40-1   Q6UX40-2   Q6UX40-3   Q6UX40-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM107: NX_Q6UX40

Explore proteomics data for TMEM107 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn79

  • See TMEM107 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_115730.2  NP_898888.1  

    ENSEMBL proteins: 
     ENSP00000404753   ENSP00000433148   ENSP00000402732   ENSP00000436674   ENSP00000314116  
     ENSP00000389420  

    TMEM107 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM107
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    Novus Biologicals TMEM107 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM107

    TMEM107 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for TMEM107
    Cloud-Clone Corp. Antibodies for TMEM107
    Search ThermoFisher Antibodies for TMEM107
    LSBio Antibodies in human, mouse, rat for TMEM107

    TMEM107 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for TMEM107
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM107
    Cloud-Clone Corp. CLIAs for TMEM107


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q6UX40


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM107_HUMAN, Q6UX40
    Function: Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh)
    signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate
    neuronal cell types (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    TMEM107 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TMEM107:
     Decreased number of cells in m  Increased gamma-H2AX phosphory 

         12 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Tmem107):
     cellular  craniofacial  digestive/alimentary  embryogenesis  growth/size/body 
     limbs/digits/tail  liver/biliary system  mortality/aging  nervous system  renal/urinary system 
     skeleton  vision/eye 

    TMEM107 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tmem107tm1Lex for TMEM107

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM107
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM107

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM107
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM107

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM107:
    hsa-let-7e-5p (MIRT051417), hsa-mir-652-3p (MIRT039501)

    Block miRNA regulation of human, mouse, rat TMEM107 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM107 (see all 15):
    hsa-miR-520d-5p hsa-miR-324-3p hsa-miR-1224-3p hsa-miR-4297 hsa-miR-4290 hsa-miR-609 hsa-miR-3159 hsa-miR-3667-3p
    SwitchGear 3'UTR luciferase reporter plasmidTMEM107 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM107
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM107

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM107

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM107 (see all 13)
    OriGene ORF clones in mouse, rat for TMEM107
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM107 (NM_032354)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM107
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM107

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM107
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM107 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM107


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM107_HUMAN, Q6UX40: Membrane; Multi-pass membrane protein (Potential)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0016021integral component of membrane IEA--

    TMEM107 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM107
    Interactions:

        Search GeneGlobe Interaction Network for TMEM107

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0021532neural tube patterning IEA--
    GO:0042384cilium assembly ISS--
    GO:0042733embryonic digit morphogenesis IEA--

    TMEM107 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM107 (TM107)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TMEM107 gene (2 alternative transcripts): 
    NM_032354.3  NM_183065.2  

    Unigene Cluster for TMEM107:

    Transmembrane protein 107
    Hs.513933  [show with all ESTs]
    Unigene Representative Sequence: AK127891
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000449985(uc002gkg.4 uc002gkh.4 uc002gki.4 uc002gkj.4)
    ENST00000532998(uc002gkk.2) ENST00000437139 ENST00000533070 ENST00000316425
    ENST00000431792 ENST00000526920 ENST00000529756 ENST00000417073
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM107 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM107 (see all 15):
    hsa-miR-520d-5p hsa-miR-324-3p hsa-miR-1224-3p hsa-miR-4297 hsa-miR-4290 hsa-miR-609 hsa-miR-3159 hsa-miR-3667-3p
    SwitchGear 3'UTR luciferase reporter plasmidTMEM107 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM107
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM107
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM107 (see all 13)
    OriGene ORF clones in mouse, rat for TMEM107
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM107 (NM_032354)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM107
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM107
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM107
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM107
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM107
      QuantiFast Probe-based Assays in human, mouse, rat TMEM107

    Additional mRNA sequence: 

    AF311338.1 AK127891.1 AK315666.1 AY358525.1 BC006292.2 BC070231.1 BC119730.1 BC119731.1 
    BC127649.1 BC127650.1 

    9 DOTS entries:

    DT.100729103  DT.424880  DT.86847997  DT.100787695  DT.307661  DT.95111194  DT.100022875  DT.100787698 
    DT.92037719 

    Selected AceView cDNA sequences (see all 88):

    BF438621 AY358525 AI796088 NM_183065 BX387529 BC006292 AW015797 NM_032354 
    AA364444 AI742969 BM706646 BM768665 BQ022554 BM906606 AA922142 AK027813 
    CD385751 BQ448612 BU852346 BX465148 AI761921 BE049359 BF971873 BF884352 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM107 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e
    SP1:                                            -                                                   
    SP2:                                            -                 -                                 
    SP3:                                -           -                                                   
    SP4:                                -           -                 -                                 
    SP5:                                            -                                                   


    ECgene alternative splicing isoforms for TMEM107

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM107 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAACGTGATT
    TMEM107 Expression
    About this image


    TMEM107 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
    TMEM107 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM107 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513933
        Custom PCR Arrays for TMEM107
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM107
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    QuantiFast Probe-based Assays in human, mouse, rat TMEM107
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM107

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM107 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1071 , 5 transmembrane protein 1071, 5 87.14(n)1
    88.57(a)1
      11 (42.35 cM)5
    669101  NM_025838.21  NP_080114.11 
     690708065 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM1076
    transmembrane protein 107
    68(a)
    1 ↔ 1
    GL343400.1(514729-521124)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.341372 Xenopus laevis transcribed sequences 73.42(n)    AW638348.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem107l1 transmembrane protein 107 like 62.83(n)
    63.31(a)
      559365  XM_682699.4  XP_687791.1 


    ENSEMBL Gene Tree for TMEM107 (if available)
    TreeFam Gene Tree for TMEM107 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM107 (see all 55)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs98941481,2
    C,F,A--8076166(+) GTGAGG/ACTGTC 2 -- ds50015Minor allele frequency- A:0.33NA 12
    rs1434150921,2
    C--8076193(+) AAAAA-/A/CCCAAA 2 -- ds50010--------
    rs98934741,2
    C,A--8076194(+) AAAAAA/CCAAAA 2 -- ds50012Minor allele frequency- C:0.25NA WA 4
    rs1393648371,2
    --8076194(+) AAAAA-/CCAAAAG 2 -- ds50010--------
    rs98934751,2
    C,A--8076195(+) AAAACA/CAAAAG 2 -- ds50011Minor allele frequency- C:0.00NA 2
    rs1113881081,2
    C,F--8076203(+) AAGAGG/CGGGGT 2 -- ds50012Minor allele frequency- C:0.50WA CSA 4
    rs1931355491,2
    --8078912(+) CTCTCA/GTTTTG 2 -- int10--------
    rs80644491,2
    C,F,A,H--8079029(+) GTCCTC/GATAGA 2 -- int1 ese323Minor allele frequency- G:0.44NS EA NA WA CSA EU 3643
    rs2017191101,2
    --8079179(+) GCCTGC/TAGAGA 3 Y C mis1 int10--------
    rs1508363071,2
    C--8079232(+) CTCCAC/TTCCCA 2 -- int10--------

    HapMap Linkage Disequilibrium report for TMEM107 (8076296 - 8079717 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for TMEM107:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1964CNV Insertion18451855
    nsv527475CNV Loss19592680
    nsv833353CNV Loss17160897
    nsv907658CNV Loss21882294
    dgv3056n71CNV Loss21882294
    nsv833352CNV Loss17160897
    nsv827879CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM107
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM107

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for TMEM107:    
    About MalaCards
    neuronal ceroid lipofuscinosis    neuronitis


    TMEM107 for disorders           About GeneDecksing


    Export disorders for TMEM107 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM107 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEM107)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis. (PubMed id 23142642)1 Passantino R....Guarneri P. (Biochim. Biophys. Acta 2013)
    6. Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. (PubMed id 19727342)1 Geisert E.E....Williams R.W. (Mol. Vis. 2009)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    9. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84314 HGNC: 28128 AceView: MGC10744 Ensembl:ENSG00000179029 euGenes: HUgn84314
    ECgene: TMEM107 H-InvDB: TMEM107

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TMEM107 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TMEM107 gene:
    Search GeneIP for patents involving TMEM107

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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