TMEM106B Gene
protein-coding GIFtS: 46
GCID: GC07P012217
|
|
transmembrane protein 106B
| |
Aliases
for TMEM106B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transmembrane Protein 106B1 2 | | FLJ112731 | | MGC337271 |
Export aliases for TMEM106B gene to outside databasesPrevious GC identifer: GC07P012025 |
Summaries
for TMEM106B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for TMEM106B
|
Genomic Views
for TMEM106B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TMEM106B gene promoter:
ISGF-3 Tal-1beta E4BP4 E47 NF-AT NF-AT4 NF-AT2 NF-AT3 ITF-2 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TMEM106B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM106B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p21.3 Ensembl cytogenetic band: 7p21.3 HGNC cytogenetic band: 7p21.3TMEM106B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P012217: view genomic region
(about GC identifiers)
Start:
|
12,250,848 bp from pter |
End:
|
12,276,890 bp from pter |
Size:
|
26,043 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 12,304,117-12,330,178 |
|
Proteins
for TMEM106B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: T106B_HUMAN, Q9NUM4 (See
protein sequence)Recommended Name: Transmembrane protein 106B Size: 274 amino acids; 31127 Da
Subcellular location: Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass typeII membrane protein
Secondary accessions: A4D108 Q53FL9 Q8N4L0Explore the universe of human proteins at neXtProt for TMEM106B: NX_Q9NUM4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NUM4
TMEM106B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001127704.1 NP_060844.2
ENSEMBL proteins: ENSP00000379902 ENSP00000391016 ENSP00000401302 ENSP00000379901 ENSP00000414810 ENSP00000391985
Human Recombinant Protein Products for TMEM106B:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
TMEM106B for ontologies About GeneDecksing
TMEM106B Antibody Products:
Assay Products for TMEM106B: |
Protein
Domains /
Families
for TMEM106B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TMEM106B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NUM4ProtoNet protein and cluster: Q9NUM4 UniProtKB/Swiss-Prot: T106B_HUMAN, Q9NUM4Similarity: Belongs to the TMEM106 family |
Function
for TMEM106B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
TMEM106B for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM106B (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM106B (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TMEM106B (NM_018374) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM106B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM106B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM106B |
|
Pathways & Interactions
for TMEM106B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM106B
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
TMEM106B for ontologies About GeneDecksing
|
Drugs & Compounds
for TMEM106B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TMEM106B
Search CenterWatch for drugs/clinical trials and news about TMEM106B / T106B
|
Transcripts
for TMEM106B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TMEM106B gene (2 alternative transcripts): NM_001134232.1 NM_018374.3 Unigene Cluster for TMEM106B: Transmembrane protein 106B Hs.396358 [show with all ESTs]Unigene Representative Sequence: NM_0183748 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396668 ENST00000420833 ENST00000444443 ENST00000396667(uc011jxk.2 uc003ssh.3)
ENST00000453686 ENST00000442107 ENST00000492762 ENST00000462754
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM106B (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM106B (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TMEM106B (NM_018374) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM106B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM106B |
Additional cDNA sequence: AK001834.1 AK002135.1 AK090805.1 AK223263.1 AK311651.1 BC028108.1 BC033901.2 BC039741.2 Z36806.1 12 DOTS entries: DT.114295 DT.100025181 DT.100025182 DT.92324152 DT.40114893 DT.100795422 DT.101973565 DT.92430192 DT.95365000 DT.97785316 DT.92058859 DT.99955238 24/244 AceView cDNA sequences (see all 244): CD653871 CF529047 BQ424563 AA719565 AI015782 N50372 N22544 AA730220 AA603809 BE218870 AA504163 BU160544 CK299671 AA128820 AL600186 AA730273 CB250427 BX327814 BM788784 BE048846 AA912824 BU607560 AU138150 AA304566
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM106B (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d |
|---|
|
| SP1: | | | | | | | - | | | | | | | | - | | - | | | | - | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | - | | - | | | | - | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TMEM106B
|
Expression
for TMEM106B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMEM106B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See TMEM106B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM106B
SOURCE GeneReport for Unigene cluster: Hs.396358
UniProtKB/Swiss-Prot: T106B_HUMAN, Q9NUM4Tissue specificity: Expressed in frontal cortex
SABiosciences Custom PCR Arrays for TMEM106B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM106B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM106B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM106B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM106B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM106B |
Orthologs
for TMEM106B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TMEM106B gene from 3/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
TMEM106B1 |
transmembrane protein 106B |
80.17(n)
87.59(a) |
|
420586 NM_001012558.1 NP_001012576.1 |
lizard
(Anolis carolinensis) |
Reptilia |
TMEM106B6 |
-- |
88(a) |
1 ↔ 1 |
6(25623137-25626239) |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc640132 |
hypothetical protein MGC64013 |
78.07(n) |
|
393333 BC053198.1 |
ENSEMBL Gene Tree for TMEM106B (if available)
TreeFam Gene Tree for TMEM106B (if available) |
Paralogs
for TMEM106B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TMEM106B gene
- TMEM106A2 TMEM106C2
5 SIMAP similar genes for TMEM106B using alignment to 5 protein entries: T106B_HUMAN (see all proteins):MRPS28 TMEM106C L3MBTL2 ETFA TMEM106A
TMEM106B for paralogs About GeneDecksing
|
Genomic Variants
for TMEM106B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TMEM106B (12250848 - 12276890 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TMEM106B
1 Indel: 59377 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for TMEM106B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TMEM106B for disorders About GeneDecksing
OMIM gene information: 613413
OMIM disorders: --
UniProtKB/Swiss-Prot: T106B_HUMAN, Q9NUM4
Note=TMEM106B genotype, when containing 3 particular single-nucleotide polymorphisms, is strongly correlatedwith frontotemporal lobar degeneration with TAR DNA-binding protein (TDP-43) inclusions (FTLD-TDP). Frontotemporallobar degeneration (FTLD) is the second most common cause of presenile dementia and 20% of patients with thisneurodegenerative disease have autosomal dominant GRN mutations. Expression of TMEM106B associated with thesepolymorphisms is increased in frontal cortex of patients with FTLD-TDP compared to unaffected controls. Thus,increased TMEM106B expression in the brain may be linked to mechanisms of disease in FTLD-TDP and risk alleles confergenetic susceptibility by increasing gene expression
5  diseases for TMEM106B: About MalaCardsamyotrophic lateral sclerosis frontotemporal dementia lateral sclerosis neurodegenerative disease
dementia
1 disease from the University of Copenhagen DISEASES database for TMEM106B:Frontotemporal dementia Human Genome Epidemiology (HuGE) Navigator: TMEM106B (5 documents)
Export disorders for TMEM106B gene to outside databases
|
Publications
for TMEM106B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMEM106B gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with TMEM106B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration. (PubMed id 22511793)1, 2, 3 Lang C.M.... Haass C. (2012)
- Common variants at 7p21 are associated with frontotem poral lobar degeneration with TDP-43 inclusions. (PubMed id 20154673)1, 2, 3 Van Deerlin V.M....Lee V.M. (2010)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease. (PubMed id 22855871)1 Rutherford N.J....Rademakers R. (2012)
- Genome-wide association study of Tourette's syndrome. (PubMed id 22889924)1 Scharf J.M.... D.L. (2012)
|
External Searches for TMEM106B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TMEM106B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMEM106B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMEM106B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TMEM106B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TMEM106B gene:
Search GeneIP for patents involving TMEM106B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TMEM106B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TMEM106B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM106B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM106B | | | OriGene Protein Over-expression Lysate for TMEM106B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TMEM106B | | OriGene 3'-UTR Clone for TMEM106B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM106B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM106B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMEM106B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM106B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM106B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM106B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM106B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM106B |
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 | | | TMEM106B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM106B |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM106B |
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