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TMEM104 Gene

protein-coding   GIFtS: 47
GCID: GC17P072772

Transmembrane Protein 104

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 1041 2

External Ids:    HGNC: 259841   Entrez Gene: 548682   Ensembl: ENSG000001090667   UniProtKB: Q8NE003   

Export aliases for TMEM104 gene to outside databases

Previous GC identifers: GC17P070285 GC17P068182


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM104 Gene:
TMEM104 (transmembrane protein 104) is a protein-coding gene. Diseases associated with TMEM104 include malaria.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM104 gene promoter:
         RREB-1   GCNF   Lmo2   POU2F1   POU2F1a   GCNF-1   ARP-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM104 promoter sequence
   Search Chromatin IP Primers for TMEM104

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM104


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.1

TMEM104 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM104 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P072772:  view genomic region     (about GC identifiers)

Start:
72,772,622 bp from pter      End:
72,835,922 bp from pter
Size:
63,301 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TM104_HUMAN, Q8NE00 (See protein sequence)
Recommended Name: Transmembrane protein 104  
Size: 496 amino acids; 55679 Da
Sequence caution: Sequence=BAB84855.1; Type=Erroneous initiation;
Secondary accessions: Q8TEU1 Q9NT56 Q9NXH1
Alternative splicing: 2 isoforms:  Q8NE00-1   Q8NE00-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM104: NX_Q8NE00

Explore proteomics data for TMEM104 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys381
  • Glycosylation2 at Asn193
  • Modification sites at PhosphoSitePlus

  • See TMEM104 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060198.3  
    ENSEMBL proteins: 
     ENSP00000397676   ENSP00000463774   ENSP00000463205   ENSP00000461922   ENSP00000334849  

    TMEM104 Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for TMEM104

    TMEM104 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Search for Antibodies for TMEM104 at Abcam
    Cloud-Clone Corp. Antibodies for TMEM104
    ThermoFisher Antibodies for TMEM104
    LSBio Antibodies in human, mouse, rat for TMEM104

    TMEM104 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM104
    Cloud-Clone Corp. CLIAs for TMEM104


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR013057 AA_transpt_TM

    Graphical View of Domain Structure for InterPro Entry Q8NE00

    ProtoNet protein and cluster: Q8NE00

    UniProtKB/Swiss-Prot: TM104_HUMAN, Q8NE00
    Similarity: Belongs to the TMEM104 family


    TMEM104 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    TMEM104 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM104
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM104
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM104

    miRNA
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    miRTarBase miRNAs that target TMEM104:
    hsa-mir-124-3p (MIRT022835)

    Block miRNA regulation of human, mouse, rat TMEM104 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM104 (see all 29):
    hsa-miR-644 hsa-miR-3934 hsa-miR-4307 hsa-miR-3194-5p hsa-miR-125a-3p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-449a
    SwitchGear 3'UTR luciferase reporter plasmidTMEM104 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM104
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM104

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM104

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM104 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM104
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM104 (NM_017728)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM104
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM104

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM104 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM104


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM104_HUMAN, Q8NE00: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0016021integral component of membrane IEA--

    TMEM104 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM104
    Interactions:

        Search GeneGlobe Interaction Network for TMEM104

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for TMEM104 (Q8NE003 ENSP000003348494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP36Q9P2753, ENSP000003105904I2D: score=2 STRING: ENSP00000310590
    MAPRE1Q156913I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    TMEM104 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM104 (TM104)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TMEM104 gene: 
    NM_017728.3  

    Unigene Cluster for TMEM104:

    Transmembrane protein 104
    Hs.370262  [show with all ESTs]
    Unigene Representative Sequence: NM_017728
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417024(uc010wrg.1) ENST00000578764 ENST00000582773 ENST00000584246
    ENST00000582330 ENST00000584171 ENST00000335464(uc010wrf.1 uc002jls.4 uc010dfx.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM104 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM104 (see all 29):
    hsa-miR-644 hsa-miR-3934 hsa-miR-4307 hsa-miR-3194-5p hsa-miR-125a-3p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-449a
    SwitchGear 3'UTR luciferase reporter plasmidTMEM104 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM104
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM104
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM104 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM104
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM104 (NM_017728)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM104
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM104
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM104
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM104
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM104
      QuantiFast Probe-based Assays in human, mouse, rat TMEM104

    Additional mRNA sequence: 

    AK000262.1 AK074029.1 AK291159.1 AK296621.1 AL137521.1 BC011552.1 BC037278.1 

    5 DOTS entries:

    DT.409311  DT.120899114  DT.100816826  DT.75143857  DT.75177226 

    Selected AceView cDNA sequences (see all 90):

    AW511302 AW071914 AI017060 CB215304 AA927043 CD721873 BE045696 BQ881559 
    BQ683834 BX119715 BM553264 CN479614 BU754169 CB111554 AW006209 AA479076 
    CA308316 CD672352 AK074029 BQ682253 AI694507 BG056240 CA418392 BE256763 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM104    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12
    SP1:                                      -                                         -     -     -     -         
    SP2:                                      -                                                                     
    SP3:                                      -                                                                     
    SP4:                                                                                                            
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for TMEM104

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM104 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCATTGGGTA
    TMEM104 Expression
    About this image

    TMEM104 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM104 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.370262
        Custom PCR Arrays for TMEM104
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM104
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM104

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TMEM104 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1041 , 5 transmembrane protein 1041, 5 87.77(n)1
    89.72(a)1
      11 (80.69 cM)5
    3205341  NM_001033393.21  NP_001028565.11 
     1151874875 
    chicken
    (Gallus gallus)
    Aves TMEM1041 transmembrane protein 104 77.51(n)
    82.02(a)
      422110  NM_001031107.1  NP_001026278.1 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM1046
    transmembrane protein 104
    77(a)
    1 ↔ 1
    2(115617875-115718430)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem1041 transmembrane protein 104 72.17(n)
    74.95(a)
      548779  NM_001016025.2  NP_001016025.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem1041 transmembrane protein 104 71.69(n)
    74.75(a)
      565387  XM_688664.6  XP_693756.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG52621 CG5262 51.36(n)
    44.89(a)
      40258  NM_001275180.1  NP_001262109.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C03A3.21 C03A3.2 49.07(n)
    42.06(a)
      181315  NM_077478.5  NP_509879.2 


    ENSEMBL Gene Tree for TMEM104 (if available)
    TreeFam Gene Tree for TMEM104 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM104 gene
    1 SIMAP similar gene for TMEM104 using alignment to 3 protein entries:     TM104_HUMAN (see all proteins):
    C8orf17

    TMEM104 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM104 (see all 1354)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1499699411,2
    --72774501(+) CACTGC/TCCTAA 1 -- int10--------
    rs72232321,2
    C,F,A,H--72774558(+) GCCTTG/ATACAT 1 -- int110Minor allele frequency- A:0.41NA CSA WA EA 506
    rs575144291,2
    C,F--72774560(+) CTTGTA/GCATAG 1 -- int17Minor allele frequency- G:0.11WA NA CSA EA 365
    rs129374981,2
    C,F,H--72774677(+) GAAAGC/GCTTCC 1 -- int19Minor allele frequency- G:0.35NS EA NA WA 620
    rs18794551,2
    C,F,O,A,H--72774738(-) AGAAGC/GCTCCT 1 -- int118Minor allele frequency- G:0.47NS EA NA WA CSA 886
    rs670881021,2
    C--72774804(+) TTTTT-/T/TTT 
            
    GAGAC
    2 -- int1 cds12NA 4
    rs1453146201,2
    C--72774922(+) CCTGC-/CCC   
       ACCCT
    CCCAA
    1 -- int10--------
    rs579254871,2
    C--72774926(+) CCCCA-/CCC   
       TCCCA
    AGTAG
    1 -- int10--------
    rs38378091,2
    C--72774929(-) TTGGG-/AGG   
       GTGGG
    GCAGG
    1 -- int10--------
    rs1450723761,2
    --72774954(+) AGGCAC/TGCACC 1 -- int10--------

    HapMap Linkage Disequilibrium report for TMEM104 (72772622 - 72835922 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TMEM104 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2716234CNV Deletion23290073
    esv2716233CNV Deletion23290073
    esv1113079CNV Insertion17803354
    esv1000943CNV Insertion20482838
    nsv518292CNV Loss19592680
    nsv833540CNV Loss17160897
    dgv3253n71CNV Loss21882294
    nsv908744CNV Loss21882294
    nsv457907CNV Loss19166990
    nsv908743CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM104
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM104

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for TMEM104:    
    About MalaCards
    malaria


    TMEM104 for disorders           About GeneDecksing


    Export disorders for TMEM104 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM104 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with TMEM104)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. Defining the human deubiquitinating enzyme interaction landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (Cell 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54868 HGNC: 25984 AceView: FLJ20255 Ensembl:ENSG00000109066 euGenes: HUgn54868
    ECgene: TMEM104 H-InvDB: TMEM104

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TMEM104 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TMEM104 gene:
    Search GeneIP for patents involving TMEM104

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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