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Aliases for TMEM101 Gene

Aliases for TMEM101 Gene

  • Transmembrane Protein 101 2 3
  • Putative NF-Kappa-B-Activating Protein 130 4

External Ids for TMEM101 Gene

Summaries for TMEM101 Gene

GeneCards Summary for TMEM101 Gene

TMEM101 (Transmembrane Protein 101) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity.

UniProtKB/Swiss-Prot for TMEM101 Gene

  • May activate NF-kappa-B signaling pathways.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM101 Gene

Genomics for TMEM101 Gene

Genomic Location for TMEM101 Gene

Start:
44,011,188 bp from pter
End:
44,023,946 bp from pter
Size:
12,759 bases
Orientation:
Minus strand

Genomic View for TMEM101 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM101 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM101 Gene

Regulatory Elements for TMEM101 Gene

Proteins for TMEM101 Gene

  • Protein details for TMEM101 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96IK0-TM101_HUMAN
    Recommended name:
    Transmembrane protein 101
    Protein Accession:
    Q96IK0
    Secondary Accessions:
    • B2R9N6

    Protein attributes for TMEM101 Gene

    Size:
    257 amino acids
    Molecular mass:
    28795 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM101 Gene

Proteomics data for TMEM101 Gene at MOPED

Post-translational modifications for TMEM101 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMEM101 Gene

Domains for TMEM101 Gene

Protein Domains for TMEM101 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TMEM101: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM101 Gene

Function for TMEM101 Gene

Molecular function for TMEM101 Gene

UniProtKB/Swiss-Prot Function: May activate NF-kappa-B signaling pathways.

Gene Ontology (GO) - Molecular Function for TMEM101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004871 signal transducer activity IMP 12761501
genes like me logo Genes that share ontologies with TMEM101: view
genes like me logo Genes that share phenotypes with TMEM101: view

miRNA for TMEM101 Gene

miRTarBase miRNAs that target TMEM101

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM101 Gene

Localization for TMEM101 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM101 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM101 Gene COMPARTMENTS Subcellular localization image for TMEM101 gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM101: view

Pathways for TMEM101 Gene

SuperPathways for TMEM101 Gene

No Data Available

Interacting Proteins for TMEM101 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000206380%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000380066%0d%0a
Selected Interacting proteins: ENSP00000206380 for TMEM101 Gene via STRING

Gene Ontology (GO) - Biological Process for TMEM101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IMP 12761501
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP 12761501
genes like me logo Genes that share ontologies with TMEM101: view

No data available for Pathways by source for TMEM101 Gene

Transcripts for TMEM101 Gene

Unigene Clusters for TMEM101 Gene

Transmembrane protein 101:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM101 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4
SP1: -
SP2: -
SP3:

Relevant External Links for TMEM101 Gene

GeneLoc Exon Structure for
TMEM101
ECgene alternative splicing isoforms for
TMEM101

Expression for TMEM101 Gene

mRNA expression in normal human tissues for TMEM101 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM101 Gene

SOURCE GeneReport for Unigene cluster for TMEM101 Gene Hs.514211

genes like me logo Genes that share expressions with TMEM101: view

Orthologs for TMEM101 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM101 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM101 36
  • 99.87 (n)
  • 100 (a)
TMEM101 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM101 36
  • 93.26 (n)
  • 97.28 (a)
TMEM101 37
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM101 36
  • 94.42 (n)
  • 98.44 (a)
TMEM101 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem101 36
  • 87.55 (n)
  • 98.05 (a)
Tmem101 16
Tmem101 37
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM101 37
  • 46 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem101 36
  • 88.85 (n)
  • 98.44 (a)
chicken
(Gallus gallus)
Aves LOC100859387 36
  • 78.34 (n)
  • 80.16 (a)
TMEM101 37
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM101 37
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem101 36
  • 71.01 (n)
  • 76.28 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC572154 36
  • 71.47 (n)
  • 72 (a)
tmem101 37
  • 70 (a)
OneToOne
Species with no ortholog for TMEM101:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM101 Gene

ENSEMBL:
Gene Tree for TMEM101 (if available)
TreeFam:
Gene Tree for TMEM101 (if available)

Paralogs for TMEM101 Gene

No data available for Paralogs for TMEM101 Gene

Variants for TMEM101 Gene

Sequence variations from dbSNP and Humsavar for TMEM101 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs12889 -- 44,011,485(+) CACAC(A/G/T)CACTC utr-variant-3-prime
rs170640 -- 44,017,517(-) tcctg(C/T)gttca intron-variant
rs179268 -- 44,015,436(+) tcgcc(C/T)aggct upstream-variant-2KB, intron-variant
rs183463 -- 44,015,551(+) accac(A/G)cccgg upstream-variant-2KB, intron-variant
rs228776 -- 44,010,885(-) ggcat(A/G)agcca downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TMEM101 Gene

Variant ID Type Subtype PubMed ID
nsv833454 CNV Loss 17160897

Relevant External Links for TMEM101 Gene

HapMap Linkage Disequilibrium report
TMEM101

Disorders for TMEM101 Gene

Relevant External Links for TMEM101

Genetic Association Database (GAD)
TMEM101
Human Genome Epidemiology (HuGE) Navigator
TMEM101
genes like me logo Genes that share disorders with TMEM101: view

No data available for UniProtKB/Swiss-Prot for TMEM101 Gene

Publications for TMEM101 Gene

  1. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PMID: 12761501) Matsuda A. … Sugano S. (Oncogene 2003) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. (PMID: 20532202) Naukkarinen J. … Peltonen L. (PLoS Genet. 2010) 3 49
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for TMEM101 Gene

Sources for TMEM101 Gene

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