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TMEFF1 Gene

protein-coding   GIFtS: 53
GCID: GC09P103235

Transmembrane Protein With EGF-Like And Two Follistatin-Like...


(Previous symbol: C9orf2)
  See TMEFF1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein With EGF-Like And Two Follistatin-Like Domains
11 2
     Cancer/Testis Antigen Family 1201
C9orf21 2 3     Member 11
tomoregulin-11 2     CT120.12
Transmembrane Protein With EGF-Like And One Follistatin-Like Domain2 3     Cancer/Testis Antigen Family 120, Member 12
H73652 3     C9ORF25
TR-12 3     

External Ids:    HGNC: 118661   Entrez Gene: 85772   Ensembl: ENSG000002416977   OMIM: 6034215   UniProtKB: Q8IYR63   

Export aliases for TMEFF1 gene to outside databases

Previous GC identifers: GC09P094036 GC09P094979 GC09P096693 GC09P098584 GC09P098570 GC09P100284 GC09P100315 GC09P102230 GC09P103204 GC09P072834


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEFF1 Gene:
TMEFF1 (transmembrane protein with EGF-like and two follistatin-like domains 1) is a protein-coding gene. Diseases associated with TMEFF1 include brain cancer. An important paralog of this gene is MSANTD3-TMEFF1.

UniProtKB/Swiss-Prot: TEFF1_HUMAN, Q8IYR6
Function: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor
in brain cancers




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008470.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEFF1 gene promoter:
         Max1   STAT1   Spz1   Pax-5   p300   FOXD1   STAT1beta   STAT1alpha   Pax-4a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEFF1 promoter sequence
   Search Chromatin IP Primers for TMEFF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEFF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q31   Ensembl cytogenetic band:  9q31.1   HGNC cytogenetic band: 9q31

TMEFF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEFF1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P103235:  view genomic region     (about GC identifiers)

Start:
103,204,560 bp from pter      End:
103,339,918 bp from pter
Size:
135,359 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TEFF1_HUMAN, Q8IYR6 (See protein sequence)
Recommended Name: Tomoregulin-1 precursor  
Size: 380 amino acids; 40934 Da
Subunit: May interact with ST14
Sequence caution: Sequence=AAA64622.1; Type=Frameshift; Positions=293, 297; Sequence=CAA58791.1; Type=Frameshift;
Positions=293, 297;
Secondary accessions: Q13086 Q8N3T8
Alternative splicing: 2 isoforms:  Q8IYR6-1   Q8IYR6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEFF1: NX_Q8IYR6

Explore proteomics data for TMEFF1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMEFF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003683.2  
    ENSEMBL proteins: 
     ENSP00000364013   ENSP00000334447  

    TMEFF1 Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for TMEFF1
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for TMEFF1 

     
    antibodies-online proteins for TMEFF1 (9 products) 

     
    antibodies-online peptides for TMEFF1

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    antibodies-online antibodies for TMEFF1 (30 products) 

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    Search eBioscience for ELISAs for TMEFF1 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR002350 Kazal_dom
     IPR000742 EG-like_dom
     IPR013032 EGF-like_CS

    Graphical View of Domain Structure for InterPro Entry Q8IYR6

    ProtoNet protein and cluster: Q8IYR6

    1 Blocks protein domain: IPB006210 Type I EGF

    UniProtKB/Swiss-Prot: TEFF1_HUMAN, Q8IYR6
    Similarity: Belongs to the tomoregulin family
    Similarity: Contains 1 EGF-like domain
    Similarity: Contains 2 Kazal-like domains


    Find genes that share domains with TMEFF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TEFF1_HUMAN, Q8IYR6
    Function: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor
    in brain cancers

         Genatlas biochemistry entry for TMEFF1:
    transmembrane protein with an EGF-like domain and two follistatin modules in the extra-cellular region

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TMEFF1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TMEFF1:
     Synthetic lethal with imatinib 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TMEFF1

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEFF1:
    hsa-mir-192-5p (MIRT026556), hsa-mir-215-5p (MIRT024807)

    Block miRNA regulation of human, mouse, rat TMEFF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEFF1 (see all 20):
    hsa-miR-30c hsa-miR-3607-3p hsa-miR-128 hsa-miR-30d hsa-miR-138-2* hsa-miR-373* hsa-miR-570 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidTMEFF1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TMEFF1

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    GenScript: all cDNA clones in your preferred vector: TMEFF1 (NM_003692)
    Sino Biological Human cDNA Clone for TMEFF1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEFF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEFF1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEFF1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TEFF1_HUMAN, Q8IYR6: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    endoplasmic reticulum1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEFF1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TMEFF1 About    
    See pathways by source

    SuperPathContained pathways About
    1TGF-beta Signaling Pathway (sino)
    TGF-beta Signaling Pathway


    1 Sino Biological Pathway for TMEFF1
        TGF-beta Signaling Pathway


        Pathway & Disease-focused RT2 Profiler PCR Array including TMEFF1: 
              Epithelial to Mesenchymal Transition (EMT) in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TMEFF1

    1 Interacting protein for TMEFF1 (Q8IYR63) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAC1P630003I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--

    Find genes that share ontologies with TMEFF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEFF1 (TEFF1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEFF1 gene: 
    NM_003692.4  

    Unigene Cluster for TMEFF1:

    Transmembrane protein with EGF-like and two follistatin-like domains 1
    Hs.598100  [show with all ESTs]
    Unigene Representative Sequence: NM_003692
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374879(uc004baz.2) ENST00000334943
    miRNA
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    Block miRNA regulation of human, mouse, rat TMEFF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEFF1 (see all 20):
    hsa-miR-30c hsa-miR-3607-3p hsa-miR-128 hsa-miR-30d hsa-miR-138-2* hsa-miR-373* hsa-miR-570 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidTMEFF1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TMEFF1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEFF1
    Primer
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    OriGene qPCR primer pairs and template standards for TMEFF1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEFF1
      QuantiTect SYBR Green Assays in human, mouse, rat TMEFF1
      QuantiFast Probe-based Assays in human, mouse, rat TMEFF1

    Additional mRNA sequence: 

    BC021991.1 BC035056.1 

    9 DOTS entries:

    DT.440817  DT.100750187  DT.95366242  DT.121152621  DT.315057  DT.100793021  DT.75153038  DT.91751400 
    DT.99992052 

    Selected AceView cDNA sequences (see all 207):

    CB215453 AY598327 AI623842 CA429959 CD364475 BM718343 CR616245 BM854314 
    BU681367 AF074684 BE018216 BM914752 AA193462 AA262346 BE328260 BF436262 
    BM857515 AW050404 BG033503 AI288886 AI718525 BU619044 BU741931 AA584272 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEFF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATAATATA
    TMEFF1 Expression
    About this image


    TMEFF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Presumptive Podocytes Podocyte Layer
             Metanephros
     
     Epithelial Cells
             Presumptive Podocytes Podocyte Layer
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Midbrain tegmentum
     
     Peripheral Nervous System (Nervous System)
             Schwann Precursor Cells Peripheral Nerve Domain
    TMEFF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEFF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.598100

    UniProtKB/Swiss-Prot: TEFF1_HUMAN, Q8IYR6
    Tissue specificity: Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle.
    Down-regulated in brain tumors as compared to control brain tissues

        Pathway & Disease-focused RT2 Profiler PCR Array including TMEFF1: 
              Epithelial to Mesenchymal Transition (EMT) in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEFF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TMEFF1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmeff11 , 5 transmembrane protein with EGF-like and two follistatin-like more1, 5 87.69(n)1
    94.34(a)1
      4 (26.15 cM)5
    2301571  NM_021436.21  NP_067411.11 
     485851745 
    chicken
    (Gallus gallus)
    Aves TMEFF11 transmembrane protein with EGF-like and two follistatin-like more 85.55(n)
    91.77(a)
      420985  XM_419072.4  XP_419072.4 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    80(a)
    1 → many
    4(67664325-67815251)
    African clawed frog
    (Xenopus laevis)
    Amphibia orf2 X.laevis mRNA for transmembrane protein containing more 79.84(n)    U19879.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmeff1b1 transmembrane protein with EGF-like and two follistatin-like more 61.45(n)
    59.42(a)
      553511  NM_001025301.1  NP_001020472.1 


    ENSEMBL Gene Tree for TMEFF1 (if available)
    TreeFam Gene Tree for TMEFF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEFF1 gene
    MSANTD3-TMEFF12  TMEFF22  
    1 SIMAP similar gene for TMEFF1 using alignment to 1 protein entry:     TEFF1_HUMAN:
    TMEFF2

    Find genes that share paralogs with TMEFF1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    3 SNPs for TMEFF1    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1461100041,2
    C--103245782(+) TCAAA-/AAAC/ 
    AAACAAAC
    AAACA
    1 -- int10--------
    rs1461596631,2
    C--103265818(+) CAGAA-/ACACACA 1 -- int10--------
    rs356246031,2,4
    ----see VAR_0320602 mis40--------

    HapMap Linkage Disequilibrium report for TMEFF1 (103204560 - 103339918 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TMEFF1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6639CNV Insertion18451855
    nsv893623CNV Gain21882294
    nsv825012CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEFF1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603421    OMIM disorders: --

    1 disease for TMEFF1:    
    About MalaCards
    brain cancer


    Find genes that share disorders with TMEFF1           About GenesLikeMe

    Genetic Association Database (GAD): TMEFF1
    Human Genome Epidemiology (HuGE) Navigator: TMEFF1 (1 document)

    Export disorders for TMEFF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEFF1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEFF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. (PubMed id 20583170)1, 4 Letra A....Vieira A.R. (Am. J. Med. Genet. A 2010)
    2. TMEFF1 and brain tumors. (PubMed id 12743596)1, 2 Gery S.... Koeffler H.P. (Oncogene 2003)
    3. Assignment1 of H7365 (C9orf2) to human chromosome band 9q31 by somatic cell hybrid analysis and fluorescence in situ hybridization. (PubMed id 9730596)1, 3 Eib D.W....Cremers F.P. (Cytogenet. Cell Genet. 1998)
    4. A novel transmembrane protein with epidermal growth factor and follistatin domains expressed in the hypothalamo-hypophysial axis of Xenopus laevis. (PubMed id 8752111)1, 2 Eib D.W. and Martens G.J.M. (J. Neurochem. 1996)
    5. Protein interaction analysis of ST14 domains and their point and deletion mutants. (PubMed id 16407223)2, 9 Ge W.... Zheng S. (J. Biol. Chem. 2006)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (Nature 2004)
    9. Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto. (PubMed id 14563676)1 Harms P.W. and Chang C. (amp 2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8577 HGNC: 11866 AceView: TMEFF1andMGC17337 Ensembl:ENSG00000241697 euGenes: HUgn8577
    ECgene: TMEFF1 H-InvDB: TMEFF1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEFF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEFF1 gene:
    Search GeneIP for patents involving TMEFF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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