Aliases for TMED9 Gene
External Ids for TMED9 Gene
Previous GeneCards Identifiers for TMED9 Gene
This gene is a member of a family of genes encoding transport proteins located in the endoplasmic reticulum and the Golgi. A similar gene in mouse is the target of microRNA miR-296, which is part of an imprinted cluster. [provided by RefSeq, Jul 2016]
GeneCards Summary for TMED9 Gene
TMED9 (Transmembrane P24 Trafficking Protein 9) is a Protein Coding gene. Among its related pathways are Golgi-to-ER retrograde transport and Transport to the Golgi and subsequent modification. GO annotations related to this gene include syntaxin binding. An important paralog of this gene is TMED4.
UniProtKB/Swiss-Prot for TMED9 Gene
Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.