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TMED9 Gene

protein-coding   GIFtS: 50
GCID: GC05P177019

Transmembrane Emp24 Protein Transport Domain Containing...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Emp24 Protein Transport Domain Containing 91 2     p252 3
Glycoprotein 25L22 3     HSGP25L2G2
GMP252 3     Gp25L2 Protein2
P24 Family Protein Alpha-22 3     Transmembrane Emp24 Domain-Containing Protein 92
p24alpha22 3     GP25L23

External Ids:    HGNC: 248781   Entrez Gene: 547322   Ensembl: ENSG000001848407   UniProtKB: Q9BVK63   

Export aliases for TMED9 gene to outside databases

Previous GC identifers: GC05P176952 GC05P171938


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMED9 Gene:
TMED9 (transmembrane emp24 protein transport domain containing 9) is a protein-coding gene. GO annotations related to this gene include syntaxin binding. An important paralog of this gene is TMED4.

UniProtKB/Swiss-Prot: TMED9_HUMAN, Q9BVK6
Function: Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI
vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory
pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific
retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2
and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the
ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NC_018916.2  NT_023133.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMED9 gene promoter:
         c-Fos   Max1   ER-alpha   AP-1   AML1a   Fra-1   FosB   E47   c-Jun   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMED9 promoter sequence
   Search Chromatin IP Primers for TMED9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMED9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

TMED9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMED9 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P177019:  view genomic region     (about GC identifiers)

Start:
177,019,159 bp from pter      End:
177,023,125 bp from pter
Size:
3,967 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TMED9_HUMAN, Q9BVK6 (See protein sequence)
Recommended Name: Transmembrane emp24 domain-containing protein 9 precursor  
Size: 235 amino acids; 27277 Da
Subunit: Monomer and homodimer in endoplasmic reticulum. Predominantly monomeric and to lesser extent homodimeric
in endoplasmic reticulum-Golgi intermediate compartment and cis-Golgi network. Probably oligomerizes with other
members of the EMP24/GP25L family such as TMED2, TMED7 and TMED10. Interacts with TMED5. Interacts (via
C-terminus) with COPG1; the interaction involves dimeric TMED9. Interacts with PTPN2 and SPAST. Interacts with
STX17; the interaction is direct
Sequence caution: Sequence=AAL35268.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAA62380.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q14437 Q8WZ61

Explore the universe of human proteins at neXtProt for TMED9: NX_Q9BVK6

Explore proteomics data for TMED9 at MOPED

Post-translational modifications: 

  • N-linked glycosylated containing high mannose1
  • Ubiquitination2 at Lys160, Lys180
  • Glycosylation2 at Asn125
  • Modification sites at PhosphoSitePlus

  • See TMED9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_059980.2  
    ENSEMBL proteins: 
     ENSP00000330945  

    TMED9 Human Recombinant Protein Products:

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    antibodies-online proteins for TMED9 (5 products) 

     
    antibodies-online peptides for TMED9

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009038 GOLD

    Graphical View of Domain Structure for InterPro Entry Q9BVK6

    ProtoNet protein and cluster: Q9BVK6

    1 Blocks protein domain: IPB000348 emp24/gp25L/p24 family

    UniProtKB/Swiss-Prot: TMED9_HUMAN, Q9BVK6
    Similarity: Belongs to the EMP24/GP25L family
    Similarity: Contains 1 GOLD domain


    Find genes that share domains with TMED9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TMED9_HUMAN, Q9BVK6
    Function: Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI
    vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory
    pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific
    retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2
    and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the
    ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16595549
    GO:0019905syntaxin binding IPI--
         
    Find genes that share ontologies with TMED9           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TMED9:
     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TMED9

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMED9:
    hsa-mir-124-3p (MIRT023157), hsa-mir-484 (MIRT042077), hsa-mir-324-3p (MIRT042982), hsa-mir-92a-3p (MIRT049725)

    Block miRNA regulation of human, mouse, rat TMED9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMED9 (see all 28):
    hsa-miR-411* hsa-miR-4291 hsa-miR-495 hsa-miR-125a-5p hsa-miR-379* hsa-miR-29a hsa-miR-29c hsa-miR-200a
    SwitchGear 3'UTR luciferase reporter plasmidTMED9 3' UTR sequence
    Inhib. RNA
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    Sino Biological Human cDNA Clone for TMED9
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMED9

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMED9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TMED9_HUMAN, Q9BVK6: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus,
    cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate
    compartment membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane;
    Single-pass type I membrane protein (By similarity). Note=Cycles between compartments of the early secretatory
    pathway
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    golgi apparatus5
    cytosol1
    extracellular1
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IMP18287528
    GO:0005783endoplasmic reticulum IDA12237308
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005793endoplasmic reticulum-Golgi intermediate compartment IDA12237308
    GO:0005794Golgi apparatus IDA12237308

    Find genes that share ontologies with TMED9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for TMED9
        Alzheimers Disease Pathway



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMED9
    Interactions:

        Search GeneGlobe Interaction Network for TMED9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TMED9 (Q9BVK61, 3 ENSP000003309454) via UniProtKB, MINT, STRING, and/or I2D (see all 61)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TMED10P497553, ENSP000003031454I2D: score=4 STRING: ENSP00000303145
    IKBKEQ141643, ENSP000003560874I2D: score=1 STRING: ENSP00000356087
    ACTBP607093I2D: score=1 
    ACTG1P632613I2D: score=1 
    ATP13A1Q9HD203I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0007030Golgi organization IMP18287528
    GO:0010638positive regulation of organelle organization IMP18287528
    GO:0032527NOT protein exit from endoplasmic reticulum IMP18287528
    GO:0034498NOT early endosome to Golgi transport IMP18287528

    Find genes that share ontologies with TMED9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMED9



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMED9 gene: 
    NM_017510.4  

    Unigene Cluster for TMED9:

    Transmembrane emp24 protein transport domain containing 9
    Hs.279929  [show with all ESTs]
    Unigene Representative Sequence: BX640856
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000332598(uc003mhx.3) ENST00000505521 ENST00000507723 ENST00000513799
    ENST00000507578 ENST00000510499
    miRNA
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    Block miRNA regulation of human, mouse, rat TMED9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMED9 (see all 28):
    hsa-miR-411* hsa-miR-4291 hsa-miR-495 hsa-miR-125a-5p hsa-miR-379* hsa-miR-29a hsa-miR-29c hsa-miR-200a
    SwitchGear 3'UTR luciferase reporter plasmidTMED9 3' UTR sequence
    Inhib. RNA
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMED9 (NM_017510)
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    Primer
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    OriGene qPCR primer pairs and template standards for TMED9
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMED9
      QuantiTect SYBR Green Assays in human, mouse, rat TMED9
      QuantiFast Probe-based Assays in human, mouse, rat TMED9

    Additional mRNA sequence: 

    AF441399.2 AK298435.1 AK313292.1 AY523817.1 BC001123.2 BC115367.1 BX640856.1 X90872.1 

    16 DOTS entries:

    DT.99948337  DT.447638  DT.120811561  DT.92458366  DT.95082477  DT.100886190  DT.95185987  DT.100886196 
    DT.120811559  DT.120811575  DT.100886198  DT.120811564  DT.95082419  DT.95082473  DT.120811552  DT.92407387 

    Selected AceView cDNA sequences (see all 748):

    BE907790 CR595378 AI744342 BF317383 AI656350 BQ957293 BU165101 BI051408 
    CR626796 BF725073 BM468487 CR605327 BM452299 CB068459 CR592044 AI963899 
    CR600863 BM787984 BI088567 BU162410 BE888258 AI625500 BG117087 BU850269 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMED9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTTTCCCAA
    TMED9 Expression
    About this image

    TMED9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMED9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.279929
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TMED9 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmed91 , 5 transmembrane emp24 protein transport domain containing more1, 5 87.52(n)1
    93.62(a)1
      13 (30.06 cM)5
    675111  NM_026211.31  NP_080487.21 
     555931355 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    51(a)
    many ↔ many
    4(84469235-84474602)
    lizard
    (Anolis carolinensis)
    Reptilia TMED96
    transmembrane emp24 protein transport domain conta...
    85(a)
    1 ↔ 1
    2(146098106-146106086)
    African clawed frog
    (Xenopus laevis)
    Amphibia CB197914.22   -- 79.58(n)    CB197914.2 
    zebrafish
    (Danio rerio)
    Actinopterygii sbcb2942 sbcb294 80.17(n)   368330  CF348806.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta eca6
    p24-26
    p24-related-2
    64(a)
    51(a)
    many ↔ many
    many ↔ many
    3R(5510191-5511198)
    3R(5513119-5518516)
    worm
    (Caenorhabditis elegans)
    Secernentea Y60A3A.96
    T08D2.16
    Protein T08D2.1 (T08D2.1) mRNA, complete cds
    67(a)
    55(a)
    many ↔ many
    many ↔ many
    V(19946734-19949095) WBGene00013360
    X(162529-163134) WBGene00011606
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ERP1(YAR002C-A)4 Protein that forms a heterotrimeric complex with Erp2p, more   --   1(154724-154065) 851264  NP_009402.1 


    ENSEMBL Gene Tree for TMED9 (if available)
    TreeFam Gene Tree for TMED9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMED9 gene
    TMED42  
    5 SIMAP similar genes for TMED9 using alignment to 1 protein entry:     TMED9_HUMAN:
    TMED4    TMED10    RNP24    TMED2    TMED7

    Find genes that share paralogs with TMED9           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMED9 (see all 148)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1140196921,2
    F--177017274(+) GAACTC/TCTGGG 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1478832401,2
    C--177017297(+) TCCTGC/TTTCTG 1 -- us2k10--------
    rs1415763031,2
    --177017343(+) CATGCC/TCAGCC 1 -- us2k10--------
    rs1883097961,2
    --177017355(+) ATTTTC/TACTTT 1 -- us2k10--------
    rs1931941911,2
    --177017519(+) ATGACA/GTAGTA 1 -- us2k10--------
    rs1825145481,2
    --177017633(+) TGTCTA/GTTCAA 1 -- us2k10--------
    rs1870267551,2
    C--177017635(+) TCTATC/TCAAGC 1 -- us2k10--------
    rs1911132271,2
    --177017707(+) GCATAG/TTCTGG 1 -- us2k10--------
    rs1836618301,2
    --177017932(+) TTCTAC/TGAGTT 1 -- us2k10--------
    rs287574371,2
    C,F--177018102(+) GGTCTC/ACTTGT 1 -- us2k111Minor allele frequency- A:0.41NA WA CSA EA 374

    HapMap Linkage Disequilibrium report for TMED9 (177019159 - 177023125 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TMED9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv5149CNV Insertion18451855
    nsv883181CNV Loss21882294
    nsv883183CNV Loss21882294
    nsv883182CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMED9
    DNA2.0 Custom Variant and Variant Library Synthesis for TMED9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMED9 gene, integrated from 10 sources (see all 35):
    (articles sorted by number of sources associating them with TMED9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi. (PubMed id 18287528)1, 2 Mitrovic S.... Hauri H.-P. (Mol. Biol. Cell 2008)
    2. Evidence for a role of transmembrane protein p25 in localization of protein tyrosine phosphatase TC48 to the ER. (PubMed id 16595549)1, 2 Gupta V. and Swarup G. (J. Cell Sci. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)1, 2 Zhang H.... Aebersold R. (Nat. Biotechnol. 2003)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Oligomeric state and stoichiometry of p24 proteins in the early secretory pathway. (PubMed id 12237308)1, 2 Jenne N.... Wieland F.T. (J. Biol. Chem. 2002)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    10. SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. (PubMed id 23246001)1 Xu Y....Ye Y. (Cell Rep 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54732 HGNC: 24878 AceView: HSGP25L2G Ensembl:ENSG00000184840 euGenes: HUgn54732
    ECgene: TMED9 H-InvDB: TMED9

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMED9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMED9 gene:
    Search GeneIP for patents involving TMED9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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