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Aliases for TMED10 Gene

Aliases for TMED10 Gene

  • Transmembrane P24 Trafficking Protein 10 2 3 5
  • Transmembrane Protein Tmp21 3 4
  • P24 Family Protein Delta-1 3 4
  • S31III125 3 4
  • P24delta1 3 4
  • Tmp-21-I 3 4
  • P24delta 3 4
  • S31I125 3 4
  • TMP21 3 4
  • P23 3 4
  • Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) 2
  • Transmembrane Emp24 Domain-Containing Protein 10 3
  • Transmembrane Emp24-Like Trafficking Protein 10 3
  • 21 KDa Transmembrane Trafficking Protein 3
  • 21 KDa Transmembrane-Trafficking Protein 4
  • Testicular Tissue Protein Li 206 3
  • P24(DELTA) 3
  • P24d1 3

External Ids for TMED10 Gene

Previous GeneCards Identifiers for TMED10 Gene

  • GC14M074668
  • GC14M075598
  • GC14M055766

Summaries for TMED10 Gene

Entrez Gene Summary for TMED10 Gene

  • This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]

GeneCards Summary for TMED10 Gene

TMED10 (Transmembrane P24 Trafficking Protein 10) is a Protein Coding gene. Diseases associated with TMED10 include Early-Onset Familial Alzheimer Disease. Among its related pathways are mRNA Splicing - Major Pathway and Golgi-to-ER retrograde transport. GO annotations related to this gene include protein complex binding and syntaxin binding.

UniProtKB/Swiss-Prot for TMED10 Gene

  • Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1 (By similarity). In COPI vesicle-mediated retrograde transport involved in the biogenesis of COPI vesicles and vesicle coat recruitment. On Golgi membranes, acts as primary receptor for ARF1-GDP which is involved in COPI-vesicle formation. Increases coatomer-dependent GTPase-activating activity of ARFGAP2. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2LR1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Involved in trafficking of amyloid beta A4 protein and soluble APP-beta release (independent of modulation of gamma-secretase activity). As part of the presenilin-dependent gamma-secretase complex regulates gamma-cleavages of the amyloid beta A4 protein to yield amyloid-beta 40 (Abeta40). Involved in organization of the Golgi apparatus.

Gene Wiki entry for TMED10 Gene

Additional gene information for TMED10 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMED10 Gene

Genomics for TMED10 Gene

Regulatory Elements for TMED10 Gene

Enhancers for TMED10 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H075236 1.9 VISTA FANTOM5 Ensembl ENCODE dbSUPER 11.5 -61.6 -61596 3 MXI1 HLF ZSCAN4 CEBPG MEF2D ZFHX2 POLR2A IKZF1 FOXP2 EGR2 TMED10 JDP2 ENSG00000258740 LOC105370571 RNU4ATAC14P
GH14H075293 1.7 FANTOM5 ENCODE dbSUPER 11.9 -119.8 -119792 6 HDGF PKNOX1 ARID4B SIN3A FEZF1 YBX1 ZNF2 YY1 ZNF766 ZNF143 JDP2 TMED10 NEK9 LINC01220 BATF FOS DPPA5P4 SYNDIG1L FLVCR2
GH14H075282 1.6 FANTOM5 ENCODE dbSUPER 10.8 -107.1 -107069 2 ATF1 FOXA2 TBL1XR1 ARID4B SIN3A YY1 ATF7 CREM NFYA SMAD5 TMED10 LINC01220 JDP2 FOS PROX2 GC14P075289 GC14P075290 DPPA5P4
GH14H075309 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.5 -134.5 -134490 2 MAZ RFX1 ZBTB21 MAX SIN3A ZBTB8A ZNF398 BMI1 ZIC2 RFX5 JDP2 TMED10 NEK9 MLH3 ZC2HC1C LINC01220
GH14H075221 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.4 -45.5 -45535 1 KLF1 MAZ NRF1 JUN EBF1 ZNF217 POLR2A EED IKZF1 ETV6 TMED10 JDP2 FOS DLST RNU4ATAC14P LOC105370571
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TMED10 on UCSC Golden Path with GeneCards custom track

Promoters for TMED10 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000070868 446 2401 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for TMED10 Gene

Chromosome:
14
Start:
75,131,468 bp from pter
End:
75,176,646 bp from pter
Size:
45,179 bases
Orientation:
Minus strand

Genomic View for TMED10 Gene

Genes around TMED10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMED10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMED10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMED10 Gene

Proteins for TMED10 Gene

  • Protein details for TMED10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P49755-TMEDA_HUMAN
    Recommended name:
    Transmembrane emp24 domain-containing protein 10
    Protein Accession:
    P49755
    Secondary Accessions:
    • B2R605
    • Q15602
    • Q16536
    • Q86TC2
    • Q86TS5

    Protein attributes for TMED10 Gene

    Size:
    219 amino acids
    Molecular mass:
    24976 Da
    Quaternary structure:
    • Predominantly homodimeric and to lesser extent monomeric in endoplasmic reticulum. Homodimer and monomer in endoplasmic reticulum-Golgi intermediate compartment and cis-Golgi network. Probably oligomerizes with other members of the EMP24/GP25L family such as TMED2, TMED7 and TMED9. Interacts (via GOLD domain) with TMED2 (via GOLD domain). Associates with the COPI vesicle coat (coatomer); TMED10:TMED2 heterotetramers are proposed to be involved in coatomer association. Interacts (via C-terminus) with COPG1; the interaction involves dimeric TMED10. Interacts with ARF1 (GDP-bound); the interaction probably involves a TMED10 oligomer. Interacts with SEC23A; indicative for an association of TMED10 with the COPII vesicle coat. Interacts with CD59, SEC24B, SEC24C and SEC24D (By similarity). Interacts with MPPE1/PGAP5. Interacts with F2LR1. Interacts with KDELR2; the interaction is disrupted by KDELR2 ligand (By similarity). Found in a complex composed at least of SURF4, TMED2 and TMED10. Associates with the presenilin-dependent gamma-secretase complex. Interacts with STX17; the interaction is direct.
    Miscellaneous:
    • Ectopic expression of TMED10 alone does not result in its proper cis-Golgi network localization. Coexpression of TMED2 is necessary, and coexpression of TMED3 and /or TMED9 is facilitating localization.
    SequenceCaution:
    • Sequence=AAC42003.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=CAD66561.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for TMED10 Gene

Post-translational modifications for TMED10 Gene

  • Ubiquitination at posLast=7575, Lys87, Lys127, Lys133, posLast=140140, and posLast=145145
  • Glycosylation at Thr55, posLast=7777, and Asn179
  • Modification sites at PhosphoSitePlus

Other Protein References for TMED10 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for TMED10 (TMED10)

No data available for DME Specific Peptides for TMED10 Gene

Domains & Families for TMED10 Gene

Gene Families for TMED10 Gene

Protein Domains for TMED10 Gene

Suggested Antigen Peptide Sequences for TMED10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P49755

UniProtKB/Swiss-Prot:

TMEDA_HUMAN :
  • The lumenal domain mediates localization to the plasma membrane by partially overriding the ER retention by the cytoplasmic domain.
  • Belongs to the EMP24/GP25L family.
Domain:
  • The lumenal domain mediates localization to the plasma membrane by partially overriding the ER retention by the cytoplasmic domain.
Family:
  • Belongs to the EMP24/GP25L family.
genes like me logo Genes that share domains with TMED10: view

Function for TMED10 Gene

Molecular function for TMED10 Gene

UniProtKB/Swiss-Prot Function:
Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1 (By similarity). In COPI vesicle-mediated retrograde transport involved in the biogenesis of COPI vesicles and vesicle coat recruitment. On Golgi membranes, acts as primary receptor for ARF1-GDP which is involved in COPI-vesicle formation. Increases coatomer-dependent GTPase-activating activity of ARFGAP2. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2LR1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Involved in trafficking of amyloid beta A4 protein and soluble APP-beta release (independent of modulation of gamma-secretase activity). As part of the presenilin-dependent gamma-secretase complex regulates gamma-cleavages of the amyloid beta A4 protein to yield amyloid-beta 40 (Abeta40). Involved in organization of the Golgi apparatus.

Phenotypes From GWAS Catalog for TMED10 Gene

Gene Ontology (GO) - Molecular Function for TMED10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 10359607
GO:0019905 syntaxin binding IPI 21545355
GO:0032403 protein complex binding IEA --
genes like me logo Genes that share ontologies with TMED10: view
genes like me logo Genes that share phenotypes with TMED10: view

Animal Model Products

  • Taconic Biosciences Mouse Models for TMED10

CRISPR Products

miRNA for TMED10 Gene

miRTarBase miRNAs that target TMED10

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TMED10
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMED10 Gene

Localization for TMED10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMED10 Gene

Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Melanosome. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type I membrane protein. Cell membrane. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Cycles between compartments of the early secretatory pathway.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMED10 gene
Compartment Confidence
plasma membrane 5
extracellular 5
endoplasmic reticulum 5
golgi apparatus 5
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TMED10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane TAS --
GO:0005783 endoplasmic reticulum IEA,IDA 12237308
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA 12237308
GO:0005794 Golgi apparatus IDA,IEA 12237308
genes like me logo Genes that share ontologies with TMED10: view

Pathways & Interactions for TMED10 Gene

genes like me logo Genes that share pathways with TMED10: view

Pathways by source for TMED10 Gene

SIGNOR curated interactions for TMED10 Gene

Activates:

Gene Ontology (GO) - Biological Process for TMED10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001822 kidney development IEA --
GO:0006810 transport IEA --
GO:0006886 intracellular protein transport IDA 20427317
GO:0006888 ER to Golgi vesicle-mediated transport TAS 20427317
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS --
genes like me logo Genes that share ontologies with TMED10: view

Drugs & Compounds for TMED10 Gene

No Compound Related Data Available

Transcripts for TMED10 Gene

Unigene Clusters for TMED10 Gene

Transmembrane emp24-like trafficking protein 10 (yeast):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TMED10
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TMED10 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d · 7e
SP1: - - - - -
SP2: - - -
SP3: - - - - -
SP4: - - - -
SP5: - - - - - -
SP6: - - - -
SP7: - -
SP8: - -

Relevant External Links for TMED10 Gene

GeneLoc Exon Structure for
TMED10
ECgene alternative splicing isoforms for
TMED10

Expression for TMED10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMED10 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TMED10 Gene



Protein tissue co-expression partners for TMED10 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TMED10 Gene:

TMED10

SOURCE GeneReport for Unigene cluster for TMED10 Gene:

Hs.74137

mRNA Expression by UniProt/SwissProt for TMED10 Gene:

P49755-TMEDA_HUMAN
Tissue specificity: Ubiquitous.

Evidence on tissue expression from TISSUES for TMED10 Gene

  • Nervous system(5)
  • Liver(4.7)
  • Pancreas(4.7)
  • Intestine(4.6)
  • Muscle(4.4)
  • Lung(3.8)
  • Skin(3.5)
  • Eye(2.4)
  • Gall bladder(2.3)
  • Thyroid gland(2.2)
  • Kidney(2.1)
  • Heart(2)
  • Stomach(2)
genes like me logo Genes that share expression patterns with TMED10: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMED10 Gene

Orthologs for TMED10 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TMED10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMED10 33 34
  • 99.54 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia TMED10 34
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMED10 33 34
  • 92.24 (n)
cow
(Bos Taurus)
Mammalia TMED10 33 34
  • 91.48 (n)
mouse
(Mus musculus)
Mammalia Tmed10 33 34
  • 89.35 (n)
Tmed10-ps 16
rat
(Rattus norvegicus)
Mammalia Tmed10 33
  • 88.74 (n)
oppossum
(Monodelphis domestica)
Mammalia TMED10 34
  • 79 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMED10 33 34
  • 78.66 (n)
lizard
(Anolis carolinensis)
Reptilia TMED10 34
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC549012 33
  • 73.23 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.254 33
zebrafish
(Danio rerio)
Actinopterygii tmed10 33 34
  • 77.36 (n)
Dr.26754 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001064 33
  • 59.42 (n)
fruit fly
(Drosophila melanogaster)
Insecta bai 33 34
  • 57.3 (n)
worm
(Caenorhabditis elegans)
Secernentea F47G9.1 33 34
  • 60.18 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ERV25 33 34 36
  • 48.28 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0B00935g 33
  • 48.23 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G21900 33
  • 48.23 (n)
rice
(Oryza sativa)
Liliopsida Os06g0210100 33
  • 50.9 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8367 34
  • 77 (a)
OneToOne
bread mold
(Neurospora crassa)
Ascomycetes NCU01342 33
  • 49.72 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes erv25 33
  • 45.92 (n)
Species where no ortholog for TMED10 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMED10 Gene

ENSEMBL:
Gene Tree for TMED10 (if available)
TreeFam:
Gene Tree for TMED10 (if available)

Paralogs for TMED10 Gene

(2) SIMAP similar genes for TMED10 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for TMED10 Gene

genes like me logo Genes that share paralogs with TMED10: view

No data available for Paralogs for TMED10 Gene

Variants for TMED10 Gene

Sequence variations from dbSNP and Humsavar for TMED10 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000014550 -- 75,176,877(+) ATTCT(C/T)CTTTA upstream-variant-2KB
rs1000089904 -- 75,163,842(+) CTGGT(A/T)ATGTA intron-variant
rs1000095531 -- 75,173,145(+) CTTTG(A/G)GAGGC intron-variant
rs1000147606 -- 75,173,409(+) GGAGG(G/T)GAGGG intron-variant
rs1000168389 -- 75,136,926(+) TCACA(A/C/T)CAGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMED10 Gene

Variant ID Type Subtype PubMed ID
esv2673828 CNV deletion 23128226
esv3634955 CNV gain 21293372
nsv832833 CNV gain 17160897
nsv85320 CNV deletion 16902084
nsv977488 CNV duplication 23825009

Variation tolerance for TMED10 Gene

Residual Variation Intolerance Score: 31.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.16; 3.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMED10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMED10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMED10 Gene

Disorders for TMED10 Gene

MalaCards: The human disease database

(1) MalaCards diseases for TMED10 Gene - From: GeneCards

Disorder Aliases PubMed IDs
early-onset familial alzheimer disease
  • eofad
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for TMED10

Genetic Association Database (GAD)
TMED10
Human Genome Epidemiology (HuGE) Navigator
TMED10
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMED10
genes like me logo Genes that share disorders with TMED10: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TMED10 Gene

Publications for TMED10 Gene

  1. Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking. (PMID: 8663407) Blum R … Schulz I (The Journal of biological chemistry 1996) 2 3 4 60
  2. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. (PMID: 7596406) Sherrington R … St George-Hyslop PH (Nature 1995) 2 3 4 60
  3. Syntaxin 17 cycles between the ER and ERGIC and is required to maintain the architecture of ERGIC and Golgi. (PMID: 21545355) Muppirala M … Swarup G (Biology of the cell 2011) 3 4 60
  4. Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking. (PMID: 21219331) Luo W … Reiser G (Journal of neurochemistry 2011) 3 4 60
  5. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PMID: 20546612) Zhao J … Grant SF (BMC medical genetics 2010) 3 45 60

Products for TMED10 Gene

Sources for TMED10 Gene

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