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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMCO6 Gene

protein-coding   GIFtS: 46
GCID: GC05P140019

Transmembrane And Coiled-Coil Domains 6

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane And Coiled-Coil Domains 61 2
Transmembrane And Coiled-Coil Domain-Containing Protein 62

External Ids:    HGNC: 288141   Entrez Gene: 553742   Ensembl: ENSG000001131197   UniProtKB: Q96DC73   

Export aliases for TMCO6 gene to outside databases

Previous GC identifers: GC05P140000 GC05P140001 GC05P135164


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TMCO6 Gene: 
TMCO6 (transmembrane and coiled-coil domains 6) is a protein-coding gene. Diseases associated with TMCO6 include meningioma, and leukemia. GO annotations related to this gene include protein transporter activity.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_029289.11  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMCO6 gene promoter:
         CREB   AP-1   ATF-2   deltaCREB   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMCO6 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMCO6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMCO6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.3   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31.3

TMCO6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMCO6 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P140019:  view genomic region     (about GC identifiers)

Start:
140,019,012 bp from pter      End:
140,024,993 bp from pter
Size:
5,982 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TMCO6_HUMAN, Q96DC7 (See protein sequence)
Recommended Name: Transmembrane and coiled-coil domain-containing protein 6  
Size: 493 amino acids; 54442 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAF69602.1; Type=Miscellaneous discrepancy; Note=Chimeric cDNA; Sequence=AAH01910.1;
Type=Erroneous initiation; Sequence=AAH09618.1; Type=Erroneous initiation; Sequence=EAW62034.1; Type=Erroneous
gene model prediction;
Secondary accessions: Q9BUU0 Q9P198
Alternative splicing: 2 isoforms:  Q96DC7-1   Q96DC7-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMCO6: NX_Q96DC7

Explore proteomics data for TMCO6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96DC7

  • TMCO6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMCO6 Protein Expression
    REFSEQ proteins: NP_060972.3  
    ENSEMBL proteins: 
     ENSP00000378166   ENSP00000421613   ENSP00000424937   ENSP00000422154   ENSP00000445469  
     ENSP00000443223   ENSP00000423297   ENSP00000426221   ENSP00000252100   ENSP00000444474  

    Human Recombinant Protein Products for TMCO6: 
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMCO6
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TMCO6
    GenScript Custom Purified and Recombinant Proteins Services for TMCO6
    Novus Biologicals TMCO6 Protein
    Novus Biologicals TMCO6 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMCO6 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0016021integral to membrane IEA--

    TMCO6 for ontologies           About GeneDecksing



    TMCO6 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    OriGene Custom Antibody Services for TMCO6
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    Novus Biologicals TMCO6 Antibodies
    Abcam antibodies for TMCO6
    Cloud-Clone Corp. Antibodies for TMCO6 
    ThermoFisher Antibodies for TMCO6
    LSBio Antibodies in human, mouse, rat for TMCO6 

    Assay Products for TMCO6: 
    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMCO6
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMCO6 
    Cloud-Clone Corp. CLIAs for TMCO6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR011989 ARM-like
     IPR000225 Armadillo
     IPR002652 Importin-a_IBB
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q96DC7

    ProtoNet protein and cluster: Q96DC7


    TMCO6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
    GO:0008565protein transporter activity IEA--
         
    TMCO6 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMCO6 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMCO6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMCO6 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMCO6 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMCO6
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMCO6:
    hsa-miR-3163 hsa-miR-296-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidTMCO6 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMCO6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMCO6

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMCO6
    Sirion Biotech Customized adenovirus for overexpression of TMCO6

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TMCO6 (see all 7)
    OriGene ORF clones in mouse, rat for TMCO6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMCO6 (NM_018502)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMCO6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCO6
    Sirion Biotech Customized lentivirus for stable overexpression of TMCO6 
                         Customized lentivirus expression plasmids for stable overexpression of TMCO6 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMCO6
    Search LifeMap BioReagents cell lines for TMCO6
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCO6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMCO6

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for TMCO6 (Q96DC72, 3 ENSP000003781664) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBQLN1Q9UMX02, 3, ENSP000003655764MINT-66792 I2D: score=5 STRING: ENSP00000365576
    ELOF1P600023I2D: score=1 
    UBQLN2ENSP000003451954STRING: ENSP00000345195
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006606protein import into nucleus IEA--

    TMCO6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMCO6

    Search CenterWatch for drugs/clinical trials and news about TMCO6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMCO6 gene: 
    NM_018502.3  

    Unigene Cluster for TMCO6:

    Transmembrane and coiled-coil domains 6
    Hs.534333  [show with all ESTs]
    Unigene Representative Sequence: BC065828
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000394671(uc003lgl.3 uc003lgm.3 uc010jft.3) ENST00000513002
    ENST00000509217 ENST00000511410(uc011czj.1) ENST00000394669 ENST00000504069
    ENST00000515653 ENST00000514449 ENST00000505086 ENST00000252100(uc003lgo.3)
    ENST00000510336(uc003lgn.3) ENST00000509605 ENST00000515265 ENST00000509269
    ENST00000537378
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMCO6
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMCO6:
    hsa-miR-3163 hsa-miR-296-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidTMCO6 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMCO6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMCO6
    Clone
    Products:
         
    OriGene clones in human, mouse for TMCO6 (see all 7)
    OriGene ORF clones in mouse, rat for TMCO6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMCO6 (NM_018502)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMCO6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCO6
    Sirion Biotech Customized lentivirus for stable overexpression of TMCO6 
                         Customized lentivirus expression plasmids for stable overexpression of TMCO6 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMCO6
    OriGene qSTAR qPCR primer pairs in human, mouse for TMCO6
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMCO6
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMCO6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMCO6

    Additional mRNA sequence: 

    AK097088.1 AK289495.1 AK301502.1 AK308722.1 BC001910.1 BC009618.1 BC065828.1 

    14 DOTS entries:

    DT.92459893  DT.100839141  DT.100839136  DT.120833486  DT.95375434  DT.112834  DT.101980046  DT.100839131 
    DT.120833464  DT.100024343  DT.100839133  DT.102825302  DT.95375431  DT.97843997 

    24/533 AceView cDNA sequences (see all 533):

    BQ958092 BQ053593 AI420339 CR594879 AW028860 BE257207 BM794663 BM838118 
    NM_017706 BQ066786 BQ679277 BF724326 BX283942 BP352013 BQ889695 BQ072286 
    AA505575 BI769664 CB850945 BQ648469 BM450688 AW269612 BQ642413 BQ675134 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TMCO6    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7
    SP1:                                                      
    SP2:                                                      
    SP3:                          -     -                     
    SP4:                                                      


    ECgene alternative splicing isoforms for TMCO6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMCO6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TMCO6 Expression
    About this image


    See TMCO6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMCO6

    SOURCE GeneReport for Unigene cluster: Hs.534333
        SABiosciences Custom PCR Arrays for TMCO6
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMCO6
    OriGene qSTAR qPCR primer pairs in human, mouse for TMCO6
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMCO6
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMCO6
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMCO6
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCO6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TMCO6 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmco61 , 5 transmembrane and coiled-coil domains 61, 5 85.03(n)1
    83.67(a)1
      18 (19.46 cM)5
    719831  NM_028036.31  NP_082312.31 
     367350705 
    chicken
    (Gallus gallus)
    Aves TMCO61 transmembrane and coiled-coil domains 6 63.56(n)
    59.09(a)
      416135  XM_414468.3  XP_414468.3 
    lizard
    (Anolis carolinensis)
    Reptilia TMCO66
    Uncharacterized protein
    51(a)
    1 ↔ 1
    4(77816425-77831707)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1622401 zgc:162240 54.11(n)
    48.7(a)
      559069  NM_001089537.1  NP_001083006.1 


    ENSEMBL Gene Tree for TMCO6 (if available)
    TreeFam Gene Tree for TMCO6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/223 SNPs in TMCO6 are shown (see all 223)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1816935701,2
    --140017071(+) AAAGCA/TAAAAT 1 -- us2k10--------
    rs1447529071,2
    --140017151(+) AAACCC/TGAGTG 1 -- us2k10--------
    rs1482579511,2
    --140017152(+) AACCCA/GAGTGA 1 -- us2k10--------
    rs1115038001,2
    C--140017460(+) GTCCCGCTT/-  
            
    GCCTT
    1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs2012531321,2
    C--140017462(+) CCCGC-/TTGC  
            
    CTTTC
    1 -- us2k10--------
    rs1413069571,2
    --140017523(+) CCTTCC/TTCCTT 1 -- us2k10--------
    rs1451682331,2
    --140017555(+) TCTTT-/TCTCC 
            
    CTTTC
    1 -- us2k10--------
    rs3767036221,2
    C--140017559(+) TCTCC-/CTTT  
            
    CTTTC
    1 -- us2k10--------
    rs68645801,2
    C,A--140017583(+) ttcttC/Tcttcc 1 -- us2k1 trp31Minor allele frequency- T:0.50CSA 2
    rs68645831,2
    A--140017587(+) tccttC/Tctttc 1 -- us2k1 trp30--------

    HapMap Linkage Disequilibrium report for TMCO6 (140019012 - 140024993 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TMCO6: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TMCO6
    DNA2.0 Custom Variant and Variant Library Synthesis for TMCO6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for TMCO6:    About MalaCards
    meningioma    leukemia


    TMCO6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TMCO6
    Human Genome Epidemiology (HuGE) Navigator: TMCO6 (5 documents)

    Export disorders for TMCO6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMCO6 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TMCO6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (2010)
    2. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (2010)
    3. Candidate gene polymorphisms for ischemic stroke. (PubMed id 19729601)1, 4 Matarin M....Meschia J.F. (2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    6. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)1 Rajaraman P....Chanock S.J. (2009)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55374 HGNC: 28814 AceView: IK Ensembl:ENSG00000113119 euGenes: HUgn55374
    ECgene: TMCO6 H-InvDB: TMCO6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMCO6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMCO6 gene:
    Search GeneIP for patents involving TMCO6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMCO6
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     Regulatory tfbs in TMCO6 promoter
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     Proteins for TMCO6
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     ThermoFisher Antibodies for TMCO6
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCO6
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TMCO6
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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