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Aliases for TMCO5B Gene

Aliases for TMCO5B Gene

  • Transmembrane And Coiled-Coil Domains 5B (Pseudogene) 2 3 5
  • Transmembrane And Coiled-Coil Domains 5B 2

External Ids for TMCO5B Gene

Previous GeneCards Identifiers for TMCO5B Gene

  • GC00U922816
  • GC15U900969
  • GC15M031315
  • GC15M033527

Summaries for TMCO5B Gene

GeneCards Summary for TMCO5B Gene

TMCO5B (Transmembrane And Coiled-Coil Domains 5B (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMCO5B Gene

Genomics for TMCO5B Gene

Regulatory Elements for TMCO5B Gene

Enhancers for TMCO5B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F033241 1.1 Ensembl ENCODE 12.6 +4.1 4119 4.6 CTCF JUN INSM2 RAD21 FOS MAFK TCF7L2 ZNF639 RFX1 ZNF654 TMCO5B RYR3 LOC105370759
GH15F033278 0.8 Ensembl ENCODE 5.5 -31.7 -31706 1.7 CTCF JUN ZIC2 HIC1 JUND GLIS2 ZNF692 PATZ1 GLIS1 FOSL2 RYR3 ENSG00000212415 TMCO5B LOC101928134
GH15F032700 0.2 ENCODE 5.3 +546.2 546211 1.2 CTCF TFAP4 SAP130 FEZF1 RAD21 YY1 GATA3 RERE SMC3 NR2F6 LOC105370757 SCG5 ENSG00000212415 TMCO5B LOC105370756 GREM1
GH15F033293 0.2 Ensembl 4.7 -46.4 -46380 0.4 YY1 TMCO5B LOC101928134
GH15F033226 1.3 Ensembl ENCODE 0.3 +20.9 20917 0.2 CTCF FEZF1 RAD21 TMCO5B LOC105370759
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TMCO5B on UCSC Golden Path with GeneCards custom track

Genomic Location for TMCO5B Gene

Chromosome:
15
Start:
33,235,552 bp from pter
End:
33,247,621 bp from pter
Size:
12,070 bases
Orientation:
Minus strand

Genomic View for TMCO5B Gene

Genes around TMCO5B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMCO5B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMCO5B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMCO5B Gene

Proteins for TMCO5B Gene

  • Protein details for TMCO5B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MYB1-TMC5B_HUMAN
    Recommended name:
    Transmembrane and coiled-coil domain-containing protein 5B
    Protein Accession:
    A8MYB1

    Protein attributes for TMCO5B Gene

    Size:
    307 amino acids
    Molecular mass:
    35763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMCO5B Gene

Post-translational modifications for TMCO5B Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMCO5B Gene

Domains & Families for TMCO5B Gene

Protein Domains for TMCO5B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMCO5B Gene

Graphical View of Domain Structure for InterPro Entry

A8MYB1

UniProtKB/Swiss-Prot:

TMC5B_HUMAN :
  • Belongs to the TMCO5 family.
Family:
  • Belongs to the TMCO5 family.
genes like me logo Genes that share domains with TMCO5B: view

No data available for Gene Families for TMCO5B Gene

Function for TMCO5B Gene

Phenotypes for TMCO5B Gene

GenomeRNAi human phenotypes for TMCO5B:
genes like me logo Genes that share phenotypes with TMCO5B: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMCO5B Gene

Localization for TMCO5B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMCO5B Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMCO5B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMCO5B: view

No data available for Subcellular locations from COMPARTMENTS for TMCO5B Gene

Pathways & Interactions for TMCO5B Gene

SuperPathways for TMCO5B Gene

No Data Available

Interacting Proteins for TMCO5B Gene

Gene Ontology (GO) - Biological Process for TMCO5B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMCO5B Gene

Transcripts for TMCO5B Gene

mRNA/cDNA for TMCO5B Gene

(2) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMCO5B Gene

Transmembrane and coiled-coil domains 5B, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMCO5B Gene

No ASD Table

Relevant External Links for TMCO5B Gene

GeneLoc Exon Structure for
TMCO5B
ECgene alternative splicing isoforms for
TMCO5B

Expression for TMCO5B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TMCO5B Gene

mRNA differential expression in normal tissues according to GTEx for TMCO5B Gene

This gene is overexpressed in Testis (x51.7).

Protein differential expression in normal tissues from HIPED for TMCO5B Gene

This gene is overexpressed in Blymphocyte (52.7) and Frontal cortex (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMCO5B Gene



Protein tissue co-expression partners for TMCO5B Gene

NURSA nuclear receptor signaling pathways regulating expression of TMCO5B Gene:

TMCO5B

SOURCE GeneReport for Unigene cluster for TMCO5B Gene:

Hs.439998
genes like me logo Genes that share expression patterns with TMCO5B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMCO5B Gene

Orthologs for TMCO5B Gene

Evolution for TMCO5B Gene

ENSEMBL:
Gene Tree for TMCO5B (if available)
TreeFam:
Gene Tree for TMCO5B (if available)

No data available for Orthologs for TMCO5B Gene

Paralogs for TMCO5B Gene

(1) SIMAP similar genes for TMCO5B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMCO5B: view

No data available for Paralogs for TMCO5B Gene

Variants for TMCO5B Gene

Sequence variations from dbSNP and Humsavar for TMCO5B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10519736 -- 33,245,901(+) GTCTG(C/G)TACCT nc-transcript-variant
rs111275148 -- 33,243,070(+) GGCCT(A/C)CTGAC intron-variant
rs1113180 -- 33,249,037(+) gcaca(C/T)gaaca upstream-variant-2KB
rs1113181 -- 33,249,261(+) TCTGC(C/T)CTAAA upstream-variant-2KB
rs111627597 -- 33,248,453(+) TTTTT(-/TT/TTT)AGCTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TMCO5B Gene

Variant ID Type Subtype PubMed ID
dgv4456n54 CNV gain 21841781
esv33337 CNV gain+loss 17666407
esv3892662 CNV gain 25118596
nsv1052620 CNV gain 25217958
nsv832963 CNV gain 17160897

Relevant External Links for TMCO5B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMCO5B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TMCO5B Gene

Disorders for TMCO5B Gene

Relevant External Links for TMCO5B

Human Genome Epidemiology (HuGE) Navigator
TMCO5B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMCO5B

No disorders were found for TMCO5B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMCO5B Gene

Publications for TMCO5B Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 64
  2. Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients. (PMID: 19096130) Kitahara K. … Ota M. (Dis. Markers 2008) 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for TMCO5B Gene

Sources for TMCO5B Gene

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