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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMCO3 Gene

protein-coding   GIFtS: 48
GCID: GC13P114145

Transmembrane And Coiled-Coil Domains 3

(Previous name: chromosome 13 open reading frame 11)
(Previous symbol: C13orf11)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane And Coiled-Coil Domains 31 2
C13orf111 2 3
Putative LAG1-Interacting Protein2 3
Chromosome 13 Open Reading Frame 111
B230339H12Rik2
Transmembrane And Coiled-Coil Domain-Containing Protein 32

External Ids:    HGNC: 203291   Entrez Gene: 550022   Ensembl: ENSG000001504037   UniProtKB: Q6UWJ13   

Export aliases for TMCO3 gene to outside databases

Previous GC identifers: GC13P113194 GC13P094584


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TMCO3 Gene: 
TMCO3 (transmembrane and coiled-coil domains 3) is a protein-coding gene. Diseases associated with TMCO3 include tuberculosis. GO annotations related to this gene include solute:hydrogen antiporter activity.

UniProtKB/Swiss-Prot: TMCO3_HUMAN, Q6UWJ1
Function: Probable Na(+)/H(+) antiporter (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NT_027140.6  NC_018924.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMCO3 gene promoter:
         GCNF   HTF   HNF-4alpha2   AP-4   GATA-1   HNF-4alpha1   IRF-7A   c-Myb   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMCO3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMCO3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMCO3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q34   Ensembl cytogenetic band:  13q34   HGNC cytogenetic band: 13q34

TMCO3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMCO3 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P114145:  view genomic region     (about GC identifiers)

Start:
114,145,308 bp from pter      End:
114,204,544 bp from pter
Size:
59,237 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TMCO3_HUMAN, Q6UWJ1 (See protein sequence)
Recommended Name: Transmembrane and coiled-coil domain-containing protein 3 precursor  
Size: 677 amino acids; 75598 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAM92892.1; Type=Frameshift; Positions=367, 378; Sequence=BAB85074.1; Type=Erroneous
initiation;
Secondary accessions: Q5JSB1 Q6NUN1 Q8NG29 Q8TCI6 Q96EA6 Q9NWT2
Alternative splicing: 3 isoforms:  Q6UWJ1-1   Q6UWJ1-2   Q6UWJ1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMCO3: NX_Q6UWJ1

Explore proteomics data for TMCO3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6UWJ1

  • TMCO3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMCO3 Protein Expression
    REFSEQ proteins: NP_060375.4  
    ENSEMBL proteins: 
     ENSP00000389399   ENSP00000364540  

    Human Recombinant Protein Products for TMCO3: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMCO3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    TMCO3 for ontologies           About GeneDecksing



    TMCO3 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for TMCO3 
    Cloud-Clone Corp. CLIAs for TMCO3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR006153 Cation/H_exchanger

    Graphical View of Domain Structure for InterPro Entry Q6UWJ1

    ProtoNet protein and cluster: Q6UWJ1

    1 Blocks protein domain: IPB006153 Sodium/hydrogen exchanger

    UniProtKB/Swiss-Prot: TMCO3_HUMAN, Q6UWJ1
    Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family


    TMCO3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TMCO3_HUMAN, Q6UWJ1
    Function: Probable Na(+)/H(+) antiporter (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015299solute:hydrogen antiporter activity IEA--
         
    TMCO3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TMCO3:
     Increased Salmonella enterica   Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Tmco3 (no phenotypes)

    TMCO3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tmco3tm1Lex for TMCO3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMCO3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMCO3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMCO3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMCO3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMCO3
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TMCO3:
    hsa-miR-33a* hsa-miR-124 hsa-miR-513a-3p hsa-miR-186 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidTMCO3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMCO3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMCO3

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of TMCO3

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TMCO3 (see all 5)
    OriGene ORF clones in mouse, rat for TMCO3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMCO3 (NM_017905)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMCO3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCO3
    Sirion Biotech Customized lentivirus for stable overexpression of TMCO3 
                         Customized lentivirus expression plasmids for stable overexpression of TMCO3 

    Cell Line
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    Search LifeMap BioReagents cell lines for TMCO3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCO3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMCO3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TMCO3 (Q6UWJ13 ENSP000003893994) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EGFRP005333, ENSP000002754934I2D: score=2 STRING: ENSP00000275493
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0055085transmembrane transport ----

    TMCO3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMCO3

    Search CenterWatch for drugs/clinical trials and news about TMCO3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMCO3 gene: 
    NM_017905.4  

    Unigene Cluster for TMCO3:

    Transmembrane and coiled-coil domains 3
    Hs.317593  [show with all ESTs]
    Unigene Representative Sequence: NM_017905
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000434316(uc001vtu.4) ENST00000375391 ENST00000474393(uc001vtt.4)
    ENST00000473287 ENST00000462877 ENST00000465556 ENST00000460039 ENST00000491166

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMCO3
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TMCO3:
    hsa-miR-33a* hsa-miR-124 hsa-miR-513a-3p hsa-miR-186 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidTMCO3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMCO3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMCO3
    Clone
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    OriGene clones in human, mouse for TMCO3 (see all 5)
    OriGene ORF clones in mouse, rat for TMCO3
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    GenScript: all cDNA clones in your preferred vector: TMCO3 (NM_017905)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMCO3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCO3
    Sirion Biotech Customized lentivirus for stable overexpression of TMCO3 
                         Customized lentivirus expression plasmids for stable overexpression of TMCO3 
    Primer
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    OriGene qPCR primer pairs and template standards for TMCO3
    OriGene qSTAR qPCR primer pairs in human, mouse for TMCO3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMCO3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMCO3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMCO3

    Additional mRNA sequence: 

    AF209505.1 AK000630.1 AK074415.1 AY358768.1 BC012564.1 BC068515.1 

    17 DOTS entries:

    DT.100786436  DT.95097569  DT.100786438  DT.86849611  DT.120792420  DT.120792423  DT.213962  DT.100786434 
    DT.95097571  DT.95148673  DT.100762436  DT.100843675  DT.120792430  DT.65285106  DT.91653010  DT.95097564 
    DT.99953873 

    24/136 AceView cDNA sequences (see all 136):

    BU543645 CB105050 AY358768 AI174442 AI916612 AI086982 CR601002 AL553005 
    CA489567 AA137198 BM763274 BM983620 BI092950 BU621123 CA389430 NM_017905 
    AA322989 AI753707 BX361910 BX332198 BC068515 AL544525 AI686666 AK074415 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for TMCO3 (see all 15)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d ^ 14a · 14b · 14c ^ 15 ^ 16 ^ 17 ^
    SP1:              -                                                           -     -     -                             -     -                 -     -         
    SP2:              -                                                           -     -     -                                                                     
    SP3:                                                                          -     -     -           -     -     -     -     -                 -     -         
    SP4:                                                                                                                                                            
    SP5:                                                                    -     -     -     -     -     -                 -     -                                 

    ExUns: 18 ^ 19a · 19b · 19c ^ 20a · 20b · 20c · 20d · 20e ^ 21 ^ 22a · 22b · 22c ^ 23
    SP1:  -                                                                                 
    SP2:                                                                                    
    SP3:  -                                                                                 
    SP4:                                      -     -     -           -           -         
    SP5:                                                                                    


    ECgene alternative splicing isoforms for TMCO3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMCO3 expression in normal human tissues (normalized intensities)      TMCO3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTATAATTAA
    TMCO3 Expression
    About this image


    TMCO3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Testis (Reproductive System)
             sperm   
     
     Brain (Nervous System)
             Medulla Oblongata

    See TMCO3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMCO3

    SOURCE GeneReport for Unigene cluster: Hs.317593
        SABiosciences Custom PCR Arrays for TMCO3
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMCO3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCO3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TMCO3 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmco31 , 5 transmembrane and coiled-coil domains 31, 5 83.16(n)1
    89.51(a)1
      8 (5.73 cM)5
    2340761  NM_172282.21  NP_758486.11 
     132880135 
    chicken
    (Gallus gallus)
    Aves TMCO31 transmembrane and coiled-coil domains 3 76.97(n)
    87.72(a)
      395675  NM_204867.2  NP_990198.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMCO36
    Uncharacterized protein
    79(a)
    1 ↔ 1
    3(106223839-106245468)
    zebrafish
    (Danio rerio)
    Actinopterygii tmco31 transmembrane and coiled-coil domains 3 67.24(n)
    70.53(a)
      564309  XM_002660320.2  XP_002660366.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons KEA51 K(+) efflux antiporter 5 44.35(n)
    31.53(a)
      835245  NM_124550.1  NP_568763.1 


    ENSEMBL Gene Tree for TMCO3 (if available)
    TreeFam Gene Tree for TMCO3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1892 SNPs in TMCO3 are shown (see all 1892)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1878545431,2
    --94582399(+) AATTAC/TTAAGG 1 -- us2k10--------
    rs1867958141,2
    --114147042(+) ACACCA/GTCTCT 1 -- int10--------
    rs1907956481,2
    C--114147085(+) GCGAGC/GGCCTG 1 -- int10--------
    rs1830287491,2
    --114147262(+) GTGTCA/TTTTTA 1 -- int10--------
    rs791609481,2
    C,F--114147331(+) TAGTCA/CGTAGG 1 -- int13Minor allele frequency- C:0.06NA WA 240
    rs1865226281,2
    --114147357(+) TTGAAA/GATAAA 1 -- int10--------
    rs350079081,2
    C--114147419(+) TTCAG-/TTTTCA 1 -- int10--------
    rs1909656771,2
    --114147433(+) TATGAA/GTATGT 1 -- int10--------
    rs73352661,2
    C,A--114147578(+) ATTCAC/TACATG 1 -- int13Minor allele frequency- T:0.06NA WA 240
    rs1459367091,2
    C--114147620(+) AAAATC/TCATCA 1 -- int10--------

    HapMap Linkage Disequilibrium report for TMCO3 (114145308 - 114204544 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/31 variations for TMCO3 (see all 31):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2748318CNV Deletion23290073
    esv2748312CNV Deletion23290073
    esv2748304CNV Deletion23290073
    esv2748299CNV Deletion23290073
    esv2748321CNV Deletion23290073
    dgv281e201CNV Deletion23290073
    esv2748305CNV Deletion23290073
    esv2748316CNV Deletion23290073
    esv2748314CNV Deletion23290073
    esv2748322CNV Deletion23290073

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for TMCO3:    About MalaCards
    tuberculosis    


    TMCO3 for disorders           About GeneDecksing


    Export disorders for TMCO3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMCO3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TMCO3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    7. Regulation of epidermal growth factor receptor traffi cking by lysine deacetylase HDAC6. (PubMed id 20029029)1 Deribe Y.L....Dikic I. (2009)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55002 HGNC: 20329 AceView: C13orf11 Ensembl:ENSG00000150403 euGenes: HUgn55002
    ECgene: TMCO3 H-InvDB: TMCO3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMCO3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMCO3 gene:
    Search GeneIP for patents involving TMCO3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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