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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMCO1 Gene

protein-coding   GIFtS: 49
GCID: GC01M165693

transmembrane and coiled-coil domains 1

(Previous name: transmembrane and coiled-coil domains 4 )
(Previous symbol: TMCC4)
 Explore 10 diseases affiliated with
TMCO1 via our new
 Human Malady Compendium 
Biological research products
for TMCO1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Transmembrane And Coiled-Coil Domains 11 2     PNAS-1362
TMCC41 2 3     RP11-466F5.72
HP101221 2     Putative Membrane Protein2
Transmembrane And Coiled-Coil Domains 41 2     Transmembrane And Coiled-Coil Domain-Containing Protein 12
Xenogeneic Cross-Immune Protein PCIA32 3     Transmembrane And Coiled-Coil Domains Protein 43
PCIA32     

External Ids:    HGNC: 181881   Entrez Gene: 544992   Ensembl: ENSG000001431837   OMIM: 6141235   UniProtKB: Q9UM003   

Export aliases for TMCO1 gene to outside databases

Previous GC identifers: GC01M162429 GC01M163962 GC01M136941


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TMCO1:
This locus encodes a transmembrane protein. Mutations at this locus have been associated with craniofacial dysmorphism,
skeletal anomalies, and mental retardation. Mutations at this locus have also been associated with open angle glaucoma
blindness. Alternatively spliced transcript variants have been described. (provided by RefSeq, Jan 2012)

Gene Wiki entry for TMCO1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMCO1 gene promoter:
         AhR   Elk-1   GATA-2   Meis-1b   PPAR-gamma1   Meis-1a   PPAR-gamma2   Pax-4a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMCO1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMCO1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMCO1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22-q25   Ensembl cytogenetic band:  1q24.1   HGNC cytogenetic band: 1q22-q25

TMCO1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMCO1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M165693:  view genomic region     (about GC identifiers)

Start:
165,693,528 bp from pter      End:
165,796,992 bp from pter
Size:
103,465 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TMCO1_HUMAN, Q9UM00 (See protein sequence)
Recommended Name: Transmembrane and coiled-coil domain-containing protein 1  
Size: 188 amino acids; 21175 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass
membrane protein
Sequence caution: Sequence=AAC25388.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAK07514.1; Type=Frameshift; Positions=Several; Sequence=AAK07549.1; Type=Frameshift; Positions=Several;
Secondary accessions: B2REA0 O75545 Q9BZS3 Q9BZU8
Alternative splicing: 2 isoforms:  Q9UM00-1   Q9UM00-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMCO1: NX_Q9UM00

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UM00

  • TMCO1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001243093.1  NP_001243094.1  NP_061899.2  

    ENSEMBL proteins: 
     ENSP00000356856   ENSP00000462588   ENSP00000463951   ENSP00000464127   ENSP00000462300  
     ENSP00000463105   ENSP00000375975  

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    Uscn Proteins for TMCO1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--


    TMCO1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TMCO1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR008559 UCP023322_TM_euk
     IPR002809 DUF106_TM

    Graphical View of Domain Structure for InterPro Entry Q9UM00

    ProtoNet protein and cluster: Q9UM00

    UniProtKB/Swiss-Prot: TMCO1_HUMAN, Q9UM00
    Similarity: Belongs to the TMCO1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMCO1:
    hsa-mir-30a (MIRT005185)

    OriGene 3'-UTR Clone: TMCO1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMCO1
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate TMCO1 (see all 18):
    hsa-miR-485-5p hsa-miR-378b hsa-miR-374a* hsa-miR-186 hsa-miR-155* hsa-miR-378 hsa-miR-548c-3p hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidTMCO1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCO1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMCO1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/10 Interacting proteins for TMCO1 (Q9UM003 ENSP000003568564) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GH1P012413, ENSP000003126734I2D: score=1 STRING: ENSP00000312673
    UNC93B1Q9H1C43, ENSP000002274714I2D: score=1 STRING: ENSP00000227471
    TMBIM4Q9HC243, ENSP000003509654I2D: score=1 STRING: ENSP00000350965
    GSTK1Q9Y2Q33I2D: score=1 
    TBC1D24Q9ULP93I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMCO1
    Search CenterWatch for drugs/clinical trials and news about TMCO1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMCO1 gene (3 alternative transcripts): 
    NM_001256164.1  NM_001256165.1  NM_019026.4  

    Unigene Cluster for TMCO1:

    Transmembrane and coiled-coil domains 1
    Hs.31498  [show with all ESTs]
    Unigene Representative Sequence: NM_001256165
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367881 ENST00000580248 ENST00000464650 ENST00000476143 ENST00000481278
    ENST00000465705 ENST00000392129(uc001gdk.4 uc001gdj.4 uc001gdn.4)


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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMCO1
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate TMCO1 (see all 18):
    hsa-miR-485-5p hsa-miR-378b hsa-miR-374a* hsa-miR-186 hsa-miR-155* hsa-miR-378 hsa-miR-548c-3p hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidTMCO1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMCO1 (see all 7)
    OriGene shRNA RFP: TMCO1
    OriGene siRNA: TMCO1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMCO1
    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMCO1
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    Additional cDNA sequence: 

    AB020980.1 AF070626.1 AF274935.1 AF277194.1 AK298614.1 AK316080.1 AK316610.1 AY359027.1 
    AY763589.1 BC000104.2 NR_045818.1 

    24 DOTS entries:

    DT.92458695  DT.91683188  DT.100845495  DT.100845481  DT.451618  DT.100031970  DT.95277973  DT.100845488 
    DT.121359493  DT.40233117  DT.121359658  DT.311719  DT.100845490  DT.121359702  DT.100845494  DT.100044554 
    DT.121359689  DT.121359735  DT.100833035  DT.100845485  DT.121359695  DT.311718  DT.100798708  DT.311720 

    4 AceView cDNA sequences:

    BG231693 BM551788 BC041651 AI140608 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TMCO1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c · 8d
    SP1:                                      -                 -                                                         
    SP2:                                -     -                 -                                                         
    SP3:                                                        -                                                         
    SP4:                                      -                 -                       -                                 
    SP5:                                      -           -     -                                                         


    ECgene alternative splicing isoforms for TMCO1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMCO1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGCCAGGAAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See TMCO1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMCO1

    SOURCE GeneReport for Unigene cluster: Hs.31498

    UniProtKB/Swiss-Prot: TMCO1_HUMAN, Q9UM00
    Tissue specificity: Widely expressed in adult and fetal tissues, with higher levels in thymus, prostate, testis and
    small intestine and lower levels in brain, placenta, lung and kidney

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TMCO1 gene from 9/27 species (see all 27)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmco11 , 5 transmembrane and coiled-coil domains 11, 5 90.6(n)1
    100(a)1
      1 (74.69 cM)5
    689441  NM_001039483.11  NP_001034572.11 
     1673086705 
    chicken
    (Gallus gallus)
    Aves TMCO11 transmembrane and coiled-coil domains 1 83.87(n)
    96.81(a)
      427100  XM_424693.3  XP_424693.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMCO16
    --
    93(a)
    1 ↔ 1
    4(73812906-73827466)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.252312 Xenopus laevis transcribed sequence with weak similarity more 78.46(n)    BJ038891.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sbcb7292 sbcb729 77.88(n)   378980  BQ093784.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG104701 CG10470 65.74(n)
    75.98(a)
      35174  NM_136092.1  NP_609936.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F22B5.101 Protein F22B5.10 61.99(n)
    64.04(a)
      174352  NM_063385.4  NP_495786.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G066601 hypothetical protein 52.85(n)
    48.62(a)
      830554  NM_120749.2  NP_196284.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g07214001 hypothetical protein 49.82(n)
    45.6(a)
      4333937  NM_001057639.1  NP_001051104.1 


    ENSEMBL Gene Tree for TMCO1 (if available)
    TreeFam Gene Tree for TMCO1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/975 NCBI SNPs in TMCO1 are shown (see all 975    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs115867111,2
    C,F,H,--136983660(+) gtgaaG/Agtaaa 1 -- us2k16Minor allele frequency- A:0.01NS EA NA 534
    rs557677041,2
    C,F,--136984164(+) AAACTC/TGGCTT 1 -- us2k14Minor allele frequency- T:0.06WA CSA 124
    rs791587821,2
    C,F,--136984601(+) GGCTGG/ATGTCA 1 -- us2k14Minor allele frequency- A:0.06WA CSA 124
    rs730146561,2
    C,F,--136984677(+) GCCAGA/GTTGAA 1 -- us2k15Minor allele frequency- G:0.07WA CSA 126
    rs773138371,2
    --136984768(+) GCATAA/GAAGTC 1 -- us2k12Minor allele frequency- G:0.04CSA WA 120
    rs626228031,2
    C,F,--136985529(+) AGTGAA/GGCGAA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs758408471,2
    C,--136985553(+) GACTCC/TGCCAC 1 -- us2k12Minor allele frequency- T:0.21CSA WA 120
    rs730146581,2
    C,F,--136985658(+) CACGAG/CAGTCT 1 -- nc-transcript-variant4Minor allele frequency- C:0.06WA CSA 124
    rs772913891,2
    C,F,--136986058(+) NNNNTG/ACATAC 1 -- nc-transcript-variant1Minor allele frequency- A:0.03NA 120
    rs113516681,2
    C,--136987246(+) ATAGA-/GGTATT 1 -- int10--------

    HapMap Linkage Disequilibrium report for TMCO1 (165693528 - 165796992 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for TMCO1
         1 CNV: 97539
         5 Indels: 39666 42214 60901 11422 44464
    Human Gene Mutation Database (HGMD): TMCO1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMCO1
    DNA2.0 Custom Variant and Variant Library Synthesis for TMCO1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TMCO1 for disorders           About GeneDecksing

    OMIM gene information: 614123    OMIM disorders: --

    UniProtKB/Swiss-Prot: TMCO1_HUMAN, Q9UM00
  • Defects in TMCO1 are the cause of craniofacial dysmorphism skeletal anomalies and mental retardation syndrome
  • (CFSMR) [MIM:614132]. A disorder characterized by craniofacial and skeletal anomalies, associated with mental
    retardation. Typical craniofacial dysmorphism include brachycephaly, highly arched bushy eyebrows, synophrys, long
    eyelashes, low-set ears, microdontism of primary teeth, and generalized gingival hyperplasia, whereas Sprengel
    deformity of scapula, fusion of spine, rib abnormities, pectus excavatum, and pes planus represent skeletal anomalies

    10 diseases for TMCO1:    About MalaCards
    open-angle glaucoma    glaucoma    sprengel deformity    mental retardation syndrome
    blindness    essential hypertension    hypertension    gingivitis
    malaria    prostatitis

    Human Genome Epidemiology (HuGE) Navigator: TMCO1 (1 document)

    Export disorders for TMCO1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMCO1 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with TMCO1)
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    1. Homozygous frameshift mutation in TMCO1 causes a synd rome with craniofacial dysmorphism, skeletal anomalies, and mental retardation. (PubMed id 20018682)1, 2 Xin B....Wang H. (2010)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. Multi-ubiquintination of a nascent membrane protein produced in a rabbit reticulocyte lysate. (PubMed id 10393320)1, 2 Iwamuro S.... Kato S. (1999)
    8. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (1997)
    9. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (1996)
    10. Common genetic determinants of intraocular pressure an d primary open-angle glaucoma. (PubMed id 22570627)1 van Koolwijk L.M....van Duijn C.M. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54499 HGNC: 18188 AceView: LOC54499.1 Ensembl:ENSG00000143183 euGenes: HUgn54499
    ECgene: TMCO1 H-InvDB: TMCO1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMCO1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMCO1 gene:
    Search GeneIP for patents involving TMCO1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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