Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMCC3 Gene

protein-coding   GIFtS: 48
GCID: GC12M094960

Transmembrane And Coiled-Coil Domain Family 3

(Previous name: transmembrane and coiled-coil domains 3)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane And Coiled-Coil Domain Family 31 2
Transmembrane And Coiled-Coil Domains 31 2
Transmembrane And Coiled-Coil Domains Protein 32
KIAA11453

External Ids:    HGNC: 291991   Entrez Gene: 574582   Ensembl: ENSG000000577047   UniProtKB: Q9ULS53   

Export aliases for TMCC3 gene to outside databases

Previous GC identifers: GC12M093465 GC12M092028


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMCC3 Gene:
TMCC3 (transmembrane and coiled-coil domain family 3) is a protein-coding gene. Diseases associated with TMCC3 include endotheliitis. An important paralog of this gene is TEX28P1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMCC3 gene promoter:
         NF-1/L   NF-1   Pax-5   FOXO3   MyoD   STAT5A   FOXO3b   FOXO4   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMCC3 promoter sequence
   Search Chromatin IP Primers for TMCC3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMCC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q22   Ensembl cytogenetic band:  12q22   HGNC cytogenetic band: 12q22

TMCC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMCC3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M094960:  view genomic region     (about GC identifiers)

Start:
94,960,900 bp from pter      End:
95,044,338 bp from pter
Size:
83,439 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TMCC3_HUMAN, Q9ULS5 (See protein sequence)
Recommended Name: Transmembrane and coiled-coil domains protein 3  
Size: 477 amino acids; 53785 Da
Secondary accessions: Q8IWB2

Explore the universe of human proteins at neXtProt for TMCC3: NX_Q9ULS5

Explore proteomics data for TMCC3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMCC3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065749.2  
    ENSEMBL proteins: 
     ENSP00000261226   ENSP00000449888   ENSP00000450078  

    TMCC3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMCC3
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMCC3
    GenScript Custom Purified and Recombinant Proteins Services for TMCC3
    Novus Biologicals TMCC3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMCC3

    TMCC3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMCC3
    Novus Biologicals TMCC3 Antibodies
    Abcam antibodies for TMCC3
    Cloud-Clone Corp. Antibodies for TMCC3
    Search ThermoFisher Antibodies for TMCC3
    LSBio Antibodies in human, mouse, rat for TMCC3

    TMCC3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMCC3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMCC3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMCC3
    Cloud-Clone Corp. CLIAs for TMCC3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    TMCC: Transmembrane and coiled-coil domain containing

    1 InterPro protein domain:
     IPR019394 Predicted_TM_coiled-coil_2

    Graphical View of Domain Structure for InterPro Entry Q9ULS5

    ProtoNet protein and cluster: Q9ULS5

    UniProtKB/Swiss-Prot: TMCC3_HUMAN, Q9ULS5
    Similarity: Belongs to the TEX28 family


    TMCC3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMCC3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMCC3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMCC3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMCC3

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMCC3:
    hsa-mir-26a-5p (MIRT050114), hsa-mir-335-5p (MIRT017797), hsa-mir-92a-3p (MIRT049619)

    Block miRNA regulation of human, mouse, rat TMCC3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMCC3 (see all 59):
    hsa-miR-21* hsa-miR-548j hsa-miR-1197 hsa-miR-139-5p hsa-miR-25 hsa-miR-3653 hsa-miR-449a hsa-miR-124
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMCC3
    Predesigned siRNA for gene silencing in human, mouse, rat TMCC3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMCC3

    Clone
    Products:
         
    OriGene clones in human, mouse for TMCC3 (see all 9)
    OriGene ORF clones in mouse, rat for TMCC3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMCC3 (NM_020698)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMCC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCC3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMCC3
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMCC3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCC3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TMCC3_HUMAN, Q9ULS5: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    nucleus2
    cytosol1
    endoplasmic reticulum1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    TMCC3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMCC3
    Interactions:

        Search GeneGlobe Interaction Network for TMCC3

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMCC3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMCC3 gene: 
    NM_020698.2  

    Unigene Cluster for TMCC3:

    Transmembrane and coiled-coil domain family 3
    Hs.370410  [show with all ESTs]
    Unigene Representative Sequence: NM_020698
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261226(uc001tdi.2 uc001tdj.2) ENST00000551457 ENST00000548918
    ENST00000552239
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMCC3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMCC3 (see all 59):
    hsa-miR-21* hsa-miR-548j hsa-miR-1197 hsa-miR-139-5p hsa-miR-25 hsa-miR-3653 hsa-miR-449a hsa-miR-124
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMCC3
    Predesigned siRNA for gene silencing in human, mouse, rat TMCC3
    Clone
    Products:
         
    OriGene clones in human, mouse for TMCC3 (see all 9)
    OriGene ORF clones in mouse, rat for TMCC3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMCC3 (NM_020698)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMCC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCC3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMCC3
    OriGene qSTAR qPCR primer pairs in human, mouse for TMCC3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMCC3
      QuantiTect SYBR Green Assays in human, mouse, rat TMCC3
      QuantiFast Probe-based Assays in human, mouse, rat TMCC3

    Additional mRNA sequence: 

    AB032971.1 AB073655.1 BC040535.1 

    4 DOTS entries:

    DT.110475  DT.100777026  DT.121156019  DT.100662041 

    Selected AceView cDNA sequences (see all 107):

    BQ778054 AA515537 AW024937 AI003069 CB156294 AA505358 BU952590 CK824030 
    BU751975 BM876167 BQ777749 N51805 AW954349 CR620972 T32874 CA771998 
    BF971213 BE219769 BF433078 AI279253 AA318843 BQ025083 BQ024175 AI601145 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for TMCC3    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:        -     -     -     -                     
    SP2:                    -     -                     
    SP3:                                                


    ECgene alternative splicing isoforms for TMCC3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMCC3 expression in normal human tissues (normalized intensities)      TMCC3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAGCCTAAA
    TMCC3 Expression
    About this image


    TMCC3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Myelinating Oligodendrocyte Cells Forebrain White Matter
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Cushion Mesenchymal Cells Endocardium
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Adult Endothelial Cells Blood Brain Barrier
     
     Neurons
             Type1 Off Cone Bipolar Cells Inner Nuclear Layer
     
     Epiblast (Early Embryonic Tissues)
             Epiblast-like cells
    TMCC3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMCC3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.370410
        Custom PCR Arrays for TMCC3
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMCC3
    OriGene qSTAR qPCR primer pairs in human, mouse for TMCC3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMCC3
    QuantiTect SYBR Green Assays in human, mouse, rat TMCC3
    QuantiFast Probe-based Assays in human, mouse, rat TMCC3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCC3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for TMCC3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmcc31 , 5 transmembrane and coiled coil domains 31, 5 87.56(n)1
    94.13(a)1
      10 (48.88 cM)5
    3198801  NM_172051.31  NP_742048.21 
     943119495 
    chicken
    (Gallus gallus)
    Aves TMCC31 transmembrane and coiled-coil domain family 3 77.35(n)
    86.2(a)
      417905  XM_416147.3  XP_416147.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMCC36
    transmembrane and coiled-coil domain family 3
    82(a)
    1 ↔ 1
    5(31151841-31158579)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.168092 Transcribed sequence with moderate similarity to protein more 78.13(n)    141991834 
    zebrafish
    (Danio rerio)
    Actinopterygii tmcc31 transmembrane and coiled-coil domain family 3 62.57(n)
    61.05(a)
      556763  NM_001044813.2  NP_001038278.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG10216
    --
    26(a)
    1 → many
    3R(2214884-2231613)
    worm
    (Caenorhabditis elegans)
    Secernentea C15H9.46
    Protein C15H9.4 (C15H9.4) mRNA, complete cds
    21(a)
    1 → many
    X(6101215-6105462) WBGene00015800


    ENSEMBL Gene Tree for TMCC3 (if available)
    TreeFam Gene Tree for TMCC3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMCC3 gene
    TEX28P12  TEX28P22  TMCC12  TEX282  TMCC22  
    4 SIMAP similar genes for TMCC3 using alignment to 3 protein entries:     TMCC3_HUMAN (see all proteins):
    TMCC2    TMCC1    DKFZp686H13261    TEX28

    TMCC3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMCC3 (see all 2025)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1461703821,2
    --92113128(+) TGCCAC/TCATTT 1 -- int10--------
    rs1838924831,2
    --92113255(+) AAAATA/CCCCAT 1 -- int10--------
    rs15739911,2
    C,F,H--92113289(+) TATACC/TAGACC 1 -- int114Minor allele frequency- T:0.41NS EA NA WA CSA 786
    rs1131575111,2
    C--94960506(+) AAATTG/AACTAC 1 -- ds50012Minor allele frequency- A:0.07CSA WA 119
    rs1465863601,2
    C--94960517(+) AGCGGA/GAGAGG 1 -- ds50010--------
    rs1412840451,2
    --94960659(+) TGAACC/TTTGGA 1 -- ds50010--------
    rs1454700191,2
    --94960680(+) TGTCAA/GTGCAG 1 -- ds50010--------
    rs732242301,2
    C--94960724(+) GGGAAA/TTATCG 1 -- ds50010--------
    rs787101851,2
    C--94960728(+) AATATC/TGCTAA 1 -- ds50013Minor allele frequency- T:0.05CSA WA EA 239
    rs1916828651,2
    --94960861(+) TCACAC/TACACA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for TMCC3 (94960900 - 95044338 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TMCC3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv507666CNV Insertion20534489
    nsv899444CNV Gain21882294
    nsv7234OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMCC3
    DNA2.0 Custom Variant and Variant Library Synthesis for TMCC3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for TMCC3:    About MalaCards
    endotheliitis


    TMCC3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TMCC3
    Human Genome Epidemiology (HuGE) Navigator: TMCC3 (2 documents)

    Export disorders for TMCC3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMCC3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMCC3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (DNA Res. 1999)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. A three-stage genome-wide association study of general cognitive ability: hunting the small effects. (PubMed id 20306291)1 Davis O.S....Plomin R. (Behav. Genet. 2010)
    5. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    6. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    9. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1 Nagase T.... Ohara O. (DNA Res. 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 57458 HGNC: 29199 AceView: KIAA1145 Ensembl:ENSG00000057704 euGenes: HUgn57458
    ECgene: TMCC3 H-InvDB: TMCC3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA1145

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMCC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMCC3 gene:
    Search GeneIP for patents involving TMCC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMCC3  
     OriGene qPCR primer pairs and template standards for TMCC3   OriGene Protein Over-expression Lysate for TMCC3  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMCC3  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMCC3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMCC3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMCC3   OriGene Custom Protein Services for TMCC3  

     
     
     Block miRNA regulation of human, mouse, rat TMCC3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMCC3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMCC3 Predesigned siRNA for gene silencing in human, mouse, rat TMCC3
     QuantiFast Probe-based Assays in human, mouse, rat TMCC3 QuantiTect SYBR Green Assays in human, mouse, rat TMCC3
     Custom PCR Arrays for TMCC3 Search Chromatin IP Primers for TMCC3
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMCC3  Search GeneGlobe Interaction Network for TMCC3
     Regulatory tfbs in TMCC3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMCC3 GenScript cDNA clones with any tag delivered in your preferred vector for TMCC3
     GenScript Custom Assay Services for TMCC3 GenScript Custom overexpressing Cell Line Services for TMCC3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMCC3
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMCC3 antibodies
     TMCC3 lysates
     Antibodies for TMCC3
     See all of Abcam's Antibodies, Kits and Proteins for TMCC3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMCC3
     Antibodies for TMCC3
     ELISAs for TMCC3
     CLIAs for TMCC3



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMCC3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMCC3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TMCC3
     SwitchGear Promoter luciferase reporter plasmids for TMCC3
     Search ThermoFisher Antibodies for TMCC3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMCC3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMCC3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMCC3
     LSBio Antibodies in human, mouse, rat for TMCC3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMCC3 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4